Lista de obras - Thomas Poulos - Dominio Público Uruguay

Computational analysis of the tryptophan cation radical energetics in peroxidase Compound I

artículo científico publicado en 2022

Conformational Response of N-Terminally Truncated Cytochrome P450 3A4 to Ligand Binding in Solution

scientific article published on 06 September 2019

Correction to Improvement of Cell Permeability of Human Neuronal Nitric Oxide Synthase Inhibitors Using Potent and Selective 2-Aminopyridine-Based Scaffolds with a Fluorobenzene Linker

scientific article published on 28 December 2018

Correction to Nitrile in the Hole: Discovery of a Small Auxiliary Pocket in Neuronal Nitric Oxide Synthase Leading to the Development of Potent and Selective 2-Aminoquinoline Inhibitors

artículo científico publicado en 2019

Effect of Redox Partner Binding on Cytochrome P450 Conformational Dynamics.

artículo científico publicado en 2017

First Contact: 7-Phenyl-2-Aminoquinolines, Potent and Selective Neuronal Nitric Oxide Synthase Inhibitors That Target an Isoform-Specific Aspartate

scientific article published on 17 April 2020

Hydrophilic, Potent, and Selective 7-Substituted 2-Aminoquinolines as Improved Human Neuronal Nitric Oxide Synthase Inhibitors.

artículo científico publicado en 2017

Improvement of Cell Permeability of Human Neuronal Nitric Oxide Synthase Inhibitors Using Potent and Selective 2-Aminopyridine-Based Scaffolds with a Fluorobenzene Linker.

artículo científico publicado en 2017

Inhibition Mechanisms of Human Indoleamine 2,3 Dioxygenase 1.

artículo científico publicado en 2018

Insights into the Dynamics and Dissociation Mechanism of a Protein Redox Complex Using Molecular Dynamics.

artículo científico publicado en 2017

Ligand and Redox Partner Binding Generates a New Conformational State in Cytochrome P450cam (CYP101A1)

scientific article published on 31 January 2019

Nitrile in the Hole: Discovery of a Small Auxiliary Pocket in Neuronal Nitric Oxide Synthase Leading to the Development of Potent and Selective 2-Aminoquinoline Inhibitors

artículo científico publicado en 2017

Optimization of Blood-Brain Barrier Permeability with Potent and Selective Human Neuronal Nitric Oxide Synthase Inhibitors Having a 2-Aminopyridine Scaffold

scientific article published on 25 February 2019

Structural Basis for Isoform Selective Nitric Oxide Synthase Inhibition by Thiophene-2-carboximidamides

artículo científico publicado en 2018

Substrate Dependent Allosteric Regulation in Cytochrome P450cam (CYP101A1)

artículo científico publicado en 2018

Testing the N-Terminal Velcro Model of CooA Carbon Monoxide Activation

artículo científico publicado en 2018

Ultrafast CO Kinetics in Heme Proteins: Adiabatic Ligand Binding and Heavy Atom Tunneling.

artículo científico publicado en 2017

Lista de obras de Thomas Poulos

Computational analysis of the tryptophan cation radical energetics in peroxidase Compound I

Conformational Response of N-Terminally Truncated Cytochrome P450 3A4 to Ligand Binding in Solution

Correction to Improvement of Cell Permeability of Human Neuronal Nitric Oxide Synthase Inhibitors Using Potent and Selective 2-Aminopyridine-Based Scaffolds with a Fluorobenzene Linker

Correction to Nitrile in the Hole: Discovery of a Small Auxiliary Pocket in Neuronal Nitric Oxide Synthase Leading to the Development of Potent and Selective 2-Aminoquinoline Inhibitors

Effect of Redox Partner Binding on Cytochrome P450 Conformational Dynamics.

First Contact: 7-Phenyl-2-Aminoquinolines, Potent and Selective Neuronal Nitric Oxide Synthase Inhibitors That Target an Isoform-Specific Aspartate

Hydrophilic, Potent, and Selective 7-Substituted 2-Aminoquinolines as Improved Human Neuronal Nitric Oxide Synthase Inhibitors.

Improvement of Cell Permeability of Human Neuronal Nitric Oxide Synthase Inhibitors Using Potent and Selective 2-Aminopyridine-Based Scaffolds with a Fluorobenzene Linker.

Inhibition Mechanisms of Human Indoleamine 2,3 Dioxygenase 1.

Insights into the Dynamics and Dissociation Mechanism of a Protein Redox Complex Using Molecular Dynamics.

Ligand and Redox Partner Binding Generates a New Conformational State in Cytochrome P450cam (CYP101A1)

Nitrile in the Hole: Discovery of a Small Auxiliary Pocket in Neuronal Nitric Oxide Synthase Leading to the Development of Potent and Selective 2-Aminoquinoline Inhibitors

Optimization of Blood-Brain Barrier Permeability with Potent and Selective Human Neuronal Nitric Oxide Synthase Inhibitors Having a 2-Aminopyridine Scaffold

Structural Basis for Isoform Selective Nitric Oxide Synthase Inhibition by Thiophene-2-carboximidamides

Substrate Dependent Allosteric Regulation in Cytochrome P450cam (CYP101A1)

Testing the N-Terminal Velcro Model of CooA Carbon Monoxide Activation

Ultrafast CO Kinetics in Heme Proteins: Adiabatic Ligand Binding and Heavy Atom Tunneling.