Lista de obras -

Bp44mT: an orally active iron chelator of the thiosemicarbazone class with potent anti‐tumour efficacy ⬇️

artículo científico publicado el 1 de enero de 2012

Cellular iron depletion stimulates the JNK and p38 MAPK signaling transduction pathways, dissociation of ASK1-thioredoxin, and activation of ASK1.

artículo científico publicado en 2011

Chelators at the cancer coalface: desferrioxamine to Triapine and beyond.

artículo científico publicado en 2006

Chelators to the Rescue: Different Horses for Different Courses!

artículo científico publicado en 2011

Design, synthesis, and characterization of novel iron chelators: structure-activity relationships of the 2-benzoylpyridine thiosemicarbazone series and their 3-nitrobenzoyl analogues as potent antitumor agents.

artículo científico publicado en 2007

Drug repositioning of mevalonate pathway inhibitors as antitumor agents for ovarian cancer.

artículo científico publicado en 2017

Inactivation of Arid1a in the endometrium is associated with endometrioid tumorigenesis through transcriptional reprogramming

artículo científico publicado en 2020

Inhibition of Spleen Tyrosine Kinase Potentiates Paclitaxel-Induced Cytotoxicity in Ovarian Cancer Cells by Stabilizing Microtubules.

artículo científico publicado en 2015

Inhibition of ovarian tumor cell invasiveness by targeting SYK in the tyrosine kinase signaling pathway.

artículo científico publicado en 2018

Iron chelators for the treatment of cancer.

artículo científico

Kinase Targets for Mycolic Acid Biosynthesis in Mycobacterium tuberculosis

artículo científico publicado en 2019

Mechanism of the induction of endoplasmic reticulum stress by the anti-cancer agent, di-2-pyridylketone 4,4-dimethyl-3-thiosemicarbazone (Dp44mT): Activation of PERK/eIF2α, IRE1α, ATF6 and calmodulin kinase

artículo científico publicado en 2016

Mechanisms underlying acquired platinum resistance in high grade serous ovarian cancer - a mini review

scientific article published on 10 November 2018

Melanotransferrin: search for a function.

artículo científico

Ovarian cancer stem cells and their role in drug resistance

artículo científico publicado en 2018

Pericytes promote skin regeneration by inducing epidermal cell polarity and planar cell divisions

Proteome-wide Tyrosine Phosphorylation Analysis Reveals Dysregulated Signaling Pathways in Ovarian Tumors

scientific article published on 06 December 2018

Role of glutaredoxin1 and glutathione in regulating the activity of the copper-transporting P-type ATPases, ATP7A and ATP7B.

artículo científico publicado en 2010

Spleen tyrosine kinase activity regulates epidermal growth factor receptor signaling pathway in ovarian cancer

scientific article published on 03 September 2019

The medicinal chemistry of novel iron chelators for the treatment of cancer.

artículo científico publicado en 2011

The potent and novel thiosemicarbazone chelators di-2-pyridylketone-4,4-dimethyl-3-thiosemicarbazone and 2-benzoylpyridine-4,4-dimethyl-3-thiosemicarbazone affect crucial thiol systems required for ribonucleotide reductase activity.

artículo científico publicado en 2011

Therapeutic Inducers of Apoptosis in Ovarian Cancer

scientific article published on 13 November 2019

Thiosemicarbazones from the old to new: iron chelators that are more than just ribonucleotide reductase inhibitors.

artículo científico publicado en 2009

Tuning cell cycle regulation with an iron key.

artículo científico publicado en 2007

Lista de obras de

Bp44mT: an orally active iron chelator of the thiosemicarbazone class with potent anti‐tumour efficacy ⬇️

Cellular iron depletion stimulates the JNK and p38 MAPK signaling transduction pathways, dissociation of ASK1-thioredoxin, and activation of ASK1.

Chelators at the cancer coalface: desferrioxamine to Triapine and beyond.

Chelators to the Rescue: Different Horses for Different Courses!

Design, synthesis, and characterization of novel iron chelators: structure-activity relationships of the 2-benzoylpyridine thiosemicarbazone series and their 3-nitrobenzoyl analogues as potent antitumor agents.

Drug repositioning of mevalonate pathway inhibitors as antitumor agents for ovarian cancer.

Inactivation of Arid1a in the endometrium is associated with endometrioid tumorigenesis through transcriptional reprogramming

Inhibition of Spleen Tyrosine Kinase Potentiates Paclitaxel-Induced Cytotoxicity in Ovarian Cancer Cells by Stabilizing Microtubules.

Inhibition of ovarian tumor cell invasiveness by targeting SYK in the tyrosine kinase signaling pathway.

Iron chelators for the treatment of cancer.

Kinase Targets for Mycolic Acid Biosynthesis in Mycobacterium tuberculosis

Mechanism of the induction of endoplasmic reticulum stress by the anti-cancer agent, di-2-pyridylketone 4,4-dimethyl-3-thiosemicarbazone (Dp44mT): Activation of PERK/eIF2α, IRE1α, ATF6 and calmodulin kinase

Mechanisms underlying acquired platinum resistance in high grade serous ovarian cancer - a mini review

Melanotransferrin: search for a function.

Ovarian cancer stem cells and their role in drug resistance

Pericytes promote skin regeneration by inducing epidermal cell polarity and planar cell divisions

Proteome-wide Tyrosine Phosphorylation Analysis Reveals Dysregulated Signaling Pathways in Ovarian Tumors

Role of glutaredoxin1 and glutathione in regulating the activity of the copper-transporting P-type ATPases, ATP7A and ATP7B.

Spleen tyrosine kinase activity regulates epidermal growth factor receptor signaling pathway in ovarian cancer

The medicinal chemistry of novel iron chelators for the treatment of cancer.

The potent and novel thiosemicarbazone chelators di-2-pyridylketone-4,4-dimethyl-3-thiosemicarbazone and 2-benzoylpyridine-4,4-dimethyl-3-thiosemicarbazone affect crucial thiol systems required for ribonucleotide reductase activity.

Therapeutic Inducers of Apoptosis in Ovarian Cancer

Thiosemicarbazones from the old to new: iron chelators that are more than just ribonucleotide reductase inhibitors.

Tuning cell cycle regulation with an iron key.