Lista de obras - Andrew Donson - Dominio Público Uruguay

Aurora kinase A as a rational target for therapy in glioblastoma.

artículo científico

Autophagy inhibition improves chemosensitivity in BRAF(V600E) brain tumors

artículo científico publicado en 2014

Autophagy inhibition overcomes multiple mechanisms of resistance to BRAF inhibition in brain tumors

artículo científico publicado en 2017

CD200 in CNS tumor-induced immunosuppression: the role for CD200 pathway blockade in targeted immunotherapy

artículo científico publicado en 2014

Characterization of distinct immunophenotypes across pediatric brain tumor types

scientific article published on 27 September 2013

Checkpoint kinase 1 expression is an adverse prognostic marker and therapeutic target in MYC-driven medulloblastoma

artículo científico publicado en 2016

Clinical and molecular characteristics of congenital glioblastoma

artículo científico publicado en 2012

Diffuse intrinsic pontine tumors: a study of primitive neuroectodermal tumors versus the more common diffuse intrinsic pontine gliomas

artículo científico publicado en 2012

EP-04ACTIVATION OF THE IL6/STAT3 PATHWAY IN CHILDHOOD EPENDYMOMA IS ASSOCIATED WITH A PRO-INFLAMMATORY TUMOR MICROENVIRONMENT AND A POOR PROGNOSIS.

artículo científico publicado en 2015

EPN-25ACTIVATION OF THE IL6/STAT3 PATHWAY IN CHILDHOOD EPENDYMOMA IS ASSOCIATED WITH A PRO-INFLAMMATORY TUMOR MICROENVIRONMENT AND A POOR PROGNOSIS.

artículo científico publicado en 2016

Genomic analysis of diffuse intrinsic pontine gliomas identifies three molecular subgroups and recurrent activating ACVR1 mutations

artículo científico publicado en 2014

Glycation of Glutamate Cysteine Ligase by 2-Deoxy-d-Ribose and its Potential Impact on Chemoresistance in Glioblastoma ⬇️

artículo científico publicado el 7 de junio de 2013

High expression of BMP pathway genes distinguishes a subset of atypical teratoid/rhabdoid tumors associated with shorter survival ⬇️

artículo científico publicado el 23 de septiembre de 2011

Histone deacetylase inhibition decreases proliferation and potentiates the effect of ionizing radiation in atypical teratoid/rhabdoid tumor cells.

artículo científico publicado en 2011

IM-01ANTI-TUMOR EFFECT OF TRASTUZUMAB, GM-CSF AND IL-2 COMBINATORIAL THERAPY IN PEDIATRIC EPENDYMOMA.

artículo científico publicado en 2015

IM-08INFLAMMATION DRIVER, NF-kB, IS ASSOCIATED WITH POOR OUTCOME GROUP A EPENDYMOMA AND REGULATES A KEY IMMUNE SUPPRESSIVE SIGNALING PATHWAY INVOLVED IN THE TUMOR MICROENVIRONMENT.

artículo científico publicado en 2015

Identification of targets for rational pharmacological therapy in childhood craniopharyngioma

artículo científico publicado en 2015

Immune gene and cell enrichment is associated with a good prognosis in ependymoma.

artículo científico publicado en 2009

Increased immune gene expression and immune cell infiltration in high-grade astrocytoma distinguish long-term from short-term survivors.

artículo científico publicado en 2012

Inhibition of Aurora Kinase A enhances chemosensitivity of medulloblastoma cell lines.

artículo científico publicado en 2010

Inhibition of Mer and Axl receptor tyrosine kinases in astrocytoma cells leads to increased apoptosis and improved chemosensitivity

artículo científico publicado en 2010

Inhibition of cyclin-dependent kinase 6 suppresses cell proliferation and enhances radiation sensitivity in medulloblastoma cells

artículo científico publicado en 2012

Insulin-like growth factor 2 mRNA binding protein 3 expression is an independent prognostic factor in pediatric pilocytic and pilomyxoid astrocytoma.

artículo científico publicado en 2013

Integrated genomic analysis identifies the mitotic checkpoint kinase WEE1 as a novel therapeutic target in medulloblastoma.

artículo científico publicado en 2014

Interleukin-6/STAT3 Pathway Signaling Drives an Inflammatory Phenotype in Group A Ependymoma

artículo científico publicado en 2015

MB-22CHECKPOINT KINASE 1 EXPRESSION IS AN ADVERSE PROGNOSTIC MARKER AND THERAPEUTIC TARGET IN MYC-DRIVEN MEDULLOBLASTOMA.

artículo científico publicado en 2015

MPS1 kinase as a potential therapeutic target in medulloblastoma.

artículo científico publicado en 2016

Molecular sub-group-specific immunophenotypic changes are associated with outcome in recurrent posterior fossa ependymoma

artículo científico publicado en 2013

Pediatric brainstem gangliogliomas show BRAF(V600E) mutation in a high percentage of cases

artículo científico publicado en 2013

Pediatric brainstem gangliogliomas show overexpression of neuropeptide prepronociceptin (PNOC) by microarray and immunohistochemistry

artículo científico publicado en 2012

Pediatric rhabdoid tumors of kidney and brain show many differences in gene expression but share dysregulation of cell cycle and epigenetic effector genes

artículo científico publicado en 2013

Polo-like Kinase 1 as a potential therapeutic target in Diffuse Intrinsic Pontine Glioma

artículo científico publicado en 2016

Polo-like kinase 1 (PLK1) inhibition suppresses cell growth and enhances radiation sensitivity in medulloblastoma cells

artículo científico publicado en 2012

Survey of MicroRNA expression in pediatric brain tumors

artículo científico publicado en 2010

Unique molecular characteristics of pediatric myxopapillary ependymoma

artículo científico publicado en 2010

Lista de obras de Andrew Donson

Aurora kinase A as a rational target for therapy in glioblastoma.

Autophagy inhibition improves chemosensitivity in BRAF(V600E) brain tumors

Autophagy inhibition overcomes multiple mechanisms of resistance to BRAF inhibition in brain tumors

CD200 in CNS tumor-induced immunosuppression: the role for CD200 pathway blockade in targeted immunotherapy

Characterization of distinct immunophenotypes across pediatric brain tumor types

Checkpoint kinase 1 expression is an adverse prognostic marker and therapeutic target in MYC-driven medulloblastoma

Clinical and molecular characteristics of congenital glioblastoma

Diffuse intrinsic pontine tumors: a study of primitive neuroectodermal tumors versus the more common diffuse intrinsic pontine gliomas

EP-04ACTIVATION OF THE IL6/STAT3 PATHWAY IN CHILDHOOD EPENDYMOMA IS ASSOCIATED WITH A PRO-INFLAMMATORY TUMOR MICROENVIRONMENT AND A POOR PROGNOSIS.

EPN-25ACTIVATION OF THE IL6/STAT3 PATHWAY IN CHILDHOOD EPENDYMOMA IS ASSOCIATED WITH A PRO-INFLAMMATORY TUMOR MICROENVIRONMENT AND A POOR PROGNOSIS.

Genomic analysis of diffuse intrinsic pontine gliomas identifies three molecular subgroups and recurrent activating ACVR1 mutations

Glycation of Glutamate Cysteine Ligase by 2-Deoxy-d-Ribose and its Potential Impact on Chemoresistance in Glioblastoma ⬇️

High expression of BMP pathway genes distinguishes a subset of atypical teratoid/rhabdoid tumors associated with shorter survival ⬇️

Histone deacetylase inhibition decreases proliferation and potentiates the effect of ionizing radiation in atypical teratoid/rhabdoid tumor cells.

IM-01ANTI-TUMOR EFFECT OF TRASTUZUMAB, GM-CSF AND IL-2 COMBINATORIAL THERAPY IN PEDIATRIC EPENDYMOMA.

IM-08INFLAMMATION DRIVER, NF-kB, IS ASSOCIATED WITH POOR OUTCOME GROUP A EPENDYMOMA AND REGULATES A KEY IMMUNE SUPPRESSIVE SIGNALING PATHWAY INVOLVED IN THE TUMOR MICROENVIRONMENT.

Identification of targets for rational pharmacological therapy in childhood craniopharyngioma

Immune gene and cell enrichment is associated with a good prognosis in ependymoma.

Increased immune gene expression and immune cell infiltration in high-grade astrocytoma distinguish long-term from short-term survivors.

Inhibition of Aurora Kinase A enhances chemosensitivity of medulloblastoma cell lines.

Inhibition of Mer and Axl receptor tyrosine kinases in astrocytoma cells leads to increased apoptosis and improved chemosensitivity

Inhibition of cyclin-dependent kinase 6 suppresses cell proliferation and enhances radiation sensitivity in medulloblastoma cells

Insulin-like growth factor 2 mRNA binding protein 3 expression is an independent prognostic factor in pediatric pilocytic and pilomyxoid astrocytoma.

Integrated genomic analysis identifies the mitotic checkpoint kinase WEE1 as a novel therapeutic target in medulloblastoma.

Interleukin-6/STAT3 Pathway Signaling Drives an Inflammatory Phenotype in Group A Ependymoma

MB-22CHECKPOINT KINASE 1 EXPRESSION IS AN ADVERSE PROGNOSTIC MARKER AND THERAPEUTIC TARGET IN MYC-DRIVEN MEDULLOBLASTOMA.

MPS1 kinase as a potential therapeutic target in medulloblastoma.

Molecular sub-group-specific immunophenotypic changes are associated with outcome in recurrent posterior fossa ependymoma

Pediatric brainstem gangliogliomas show BRAF(V600E) mutation in a high percentage of cases

Pediatric brainstem gangliogliomas show overexpression of neuropeptide prepronociceptin (PNOC) by microarray and immunohistochemistry

Pediatric rhabdoid tumors of kidney and brain show many differences in gene expression but share dysregulation of cell cycle and epigenetic effector genes

Polo-like Kinase 1 as a potential therapeutic target in Diffuse Intrinsic Pontine Glioma

Polo-like kinase 1 (PLK1) inhibition suppresses cell growth and enhances radiation sensitivity in medulloblastoma cells

Survey of MicroRNA expression in pediatric brain tumors

Unique molecular characteristics of pediatric myxopapillary ependymoma