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Lista de obras de Hidetsugu Asada

Bulky high-mannose-type N-glycan blocks the taste-modifying activity of miraculin

artículo científico publicado en 2010

Cloning, expression and purification of the anion exchanger 1 homologue from the basidiomycete Phanerochaete chrysosporium

artículo científico publicado en 2011

Combination vaccine of dendritic cells (DCs) and T cells effectively suppressed preestablished malignant melanoma in mice.

artículo científico publicado en 2005

Comparison of functional non-glycosylated GPCRs expression in Pichia pastoris

artículo científico publicado en 2009

Crystal structure of the human angiotensin II type 2 receptor bound to an angiotensin II analog

artículo científico publicado en 2018

Cysteine-to-serine shuffling using a Saccharomyces cerevisiae expression system improves protein secretion: case of a nonglycosylated mutant of miraculin, a taste-modifying protein.

artículo científico publicado en 2010

Electro-transfer of small interfering RNA ameliorated arthritis in rats.

artículo científico publicado en 2005

Electrochemo-gene therapy of cancer: intratumoral delivery of interleukin-12 gene and bleomycin synergistically induced therapeutic immunity and suppressed subcutaneous and metastatic melanomas in mice.

artículo científico publicado en 2003

Evaluation of the Pichia pastoris expression system for the production of GPCRs for structural analysis

artículo científico publicado en 2011

Fluorescence-based optimization of human bitter taste receptor expression in Saccharomyces cerevisiae

artículo científico publicado en 2009

Highly efficient gene transfer into murine liver achieved by intravenous administration of naked Epstein-Barr virus (EBV)-based plasmid vectors.

artículo científico publicado en 2001

In vivo electroporation-mediated transfer of interleukin-12 and interleukin-18 genes induces significant antitumor effects against melanoma in mice.

artículo científico publicado en 2001

Interleukin (IL)-21 and IL-15 genetic transfer synergistically augments therapeutic antitumor immunity and promotes regression of metastatic lymphoma.

artículo científico publicado en 2003

Interleukin-12 genetic administration suppressed metastatic liver tumor unsusceptible to CTL.

artículo científico publicado en 2004

Interleukin-21 triggers both cellular and humoral immune responses leading to therapeutic antitumor effects against head and neck squamous cell carcinoma

scientific article published on 01 January 2006

Intravascular insulin gene delivery as potential therapeutic intervention in diabetes mellitus.

artículo científico publicado en 2003

Intravascular naked DNA vaccine encoding glycoprotein B induces protective humoral and cellular immunity against herpes simplex virus type 1 infection in mice.

artículo científico publicado en 2003

Ligand binding to human prostaglandin E receptor EP4 at the lipid-bilayer interface

artículo científico publicado en 2018

Platform for the rapid construction and evaluation of GPCRs for crystallography in Saccharomyces cerevisiae

artículo científico publicado en 2012

Proteoliposome-based selection of a recombinant antibody fragment against the human M2 muscarinic acetylcholine receptor

artículo científico publicado en 2014

Sequence-specific gene silencing in murine muscle induced by electroporation-mediated transfer of short interfering RNA.

artículo científico publicado en 2004

Significant Antitumor Effects Obtained by Autologous Tumor Cell Vaccine Engineered to Secrete Interleukin (IL)-12 and IL-18 by Means of the EBV/Lipoplex

artículo científico publicado en 2002

Soluble TRAIL gene and actinomycin D synergistically suppressed multiple metastasis of TRAIL-resistant colon cancer in the liver

artículo científico publicado en 2006

Structure of the dopamine D<sub>2</sub> receptor in complex with the antipsychotic drug spiperone

artículo científico publicado en 2020

Structure of the human M2 muscarinic acetylcholine receptor bound to an antagonist

artículo científico publicado en 2012

Structures of the 5-HT2A receptor in complex with the antipsychotics risperidone and zotepine

scientific article published on 04 February 2019

The Crystal Structure of Angiotensin II Type 2 Receptor with Endogenous Peptide Hormone

scientific article published on 30 December 2019

The effect of apoptosis signal-regulating kinase 1 gene transfer on rat collagen induced arthritis.

artículo científico publicado en 2005

Transthoracic direct current shock facilitates intramyocardial transfection of naked plasmid DNA infused via coronary vessels in canines.

artículo científico publicado en 2006