Lista de obras - Aashish Manglik - Dominio Público Uruguay

A Genetically Encoded Biosensor Reveals Location Bias of Opioid Drug Action

artículo científico publicado en 2018

A comparison of chemical shift sensitivity of trifluoromethyl tags: optimizing resolution in ¹⁹F NMR studies of proteins.

artículo científico publicado en 2015

A new class of amphiphiles bearing rigid hydrophobic groups for solubilization and stabilization of membrane proteins

artículo científico publicado en 2012

Activation and allosteric modulation of a muscarinic acetylcholine receptor

artículo científico publicado en 2013

Adrenaline-activated structure of β2-adrenoceptor stabilized by an engineered nanobody

artículo científico publicado en 2013

Allosteric nanobodies reveal the dynamic range and diverse mechanisms of G-protein-coupled receptor activation

scientific article published on 13 July 2016

An ultra-high affinity synthetic nanobody blocks SARS-CoV-2 infection by locking Spike into an inactive conformation

scientific article published on 10 August 2020

An ultrapotent synthetic nanobody neutralizes SARS-CoV-2 by stabilizing inactive Spike

artículo científico publicado en 2020

Applications of molecular replacement to G protein-coupled receptors

artículo científico publicado en 2013

Bivalent binding of a fully human IgG to the SARS-CoV-2 spike proteins reveals mechanisms of potent neutralization

artículo científico publicado en 2020

Comparative host-coronavirus protein interaction networks reveal pan-viral disease mechanisms

artículo científico publicado en 2020

Covalent agonists for studying G protein-coupled receptor activation

artículo científico publicado en 2014

Crystal structure of the µ-opioid receptor bound to a morphinan antagonist

artículo científico publicado en 2012

Engineering high-affinity PD-1 variants for optimized immunotherapy and immuno-PET imaging

artículo científico publicado en 2015

Evaluation of SARS-CoV-2 serology assays reveals a range of test performance

artículo científico publicado en 2020

G Protein-coupled Receptor Kinases of the GRK4 Protein Subfamily Phosphorylate Inactive G Protein-coupled Receptors (GPCRs).

artículo científico publicado en 2015

Goniometer-based femtosecond crystallography with X-ray free electron lasers

artículo científico publicado en 2014

Hedgehog pathway activation through nanobody-mediated conformational blockade of the Patched sterol conduit

artículo científico publicado en 2020

High-density grids for efficient data collection from multiple crystals

artículo científico publicado en 2016

Nanobodies to Study G Protein-Coupled Receptor Structure and Function

artículo científico publicado en 2016

Propagation of conformational changes during μ-opioid receptor activation

artículo científico publicado en 2015

Protein design and variant prediction using autoregressive generative models

artículo científico

Role of detergents in conformational exchange of a G protein-coupled receptor

artículo científico publicado en 2012

SIGNAL TRANSDUCTION. Structural basis for nucleotide exchange in heterotrimeric G proteins

artículo científico publicado en 2015

Selective G protein signaling driven by substance P-neurokinin receptor dynamics

artículo científico publicado en 2021

Sortase ligation enables homogeneous GPCR phosphorylation to reveal diversity in β-arrestin coupling

artículo científico publicado en 2018

Structural Insights into the Dynamic Process of β2-Adrenergic Receptor Signaling

artículo científico publicado en 2015

Structural basis of odorant recognition by a human odorant receptor ⬇️

Structural insights into µ-opioid receptor activation

artículo científico publicado en 2015

Structure of active β-arrestin-1 bound to a G-protein-coupled receptor phosphopeptide

artículo científico publicado en 2013

Structure of hepcidin-bound ferroportin reveals iron homeostatic mechanisms

artículo científico publicado en 2020

Structure of the δ-opioid receptor bound to naltrindole

artículo científico publicado en 2012

Structure-based discovery of opioid analgesics with reduced side effects

artículo científico publicado en 2016

The dynamic process of β(2)-adrenergic receptor activation

artículo científico publicado en 2013

The role of ligands on the equilibria between functional states of a G protein-coupled receptor

artículo científico publicado en 2013

The role of protein dynamics in GPCR function: insights from the β2AR and rhodopsin

artículo científico publicado en 2014

Yeast surface display platform for rapid discovery of conformationally selective nanobodies.

artículo científico publicado en 2018

Lista de obras de Aashish Manglik

A Genetically Encoded Biosensor Reveals Location Bias of Opioid Drug Action

A comparison of chemical shift sensitivity of trifluoromethyl tags: optimizing resolution in ¹⁹F NMR studies of proteins.

A new class of amphiphiles bearing rigid hydrophobic groups for solubilization and stabilization of membrane proteins

Activation and allosteric modulation of a muscarinic acetylcholine receptor

Adrenaline-activated structure of β2-adrenoceptor stabilized by an engineered nanobody

Allosteric nanobodies reveal the dynamic range and diverse mechanisms of G-protein-coupled receptor activation

An ultra-high affinity synthetic nanobody blocks SARS-CoV-2 infection by locking Spike into an inactive conformation

An ultrapotent synthetic nanobody neutralizes SARS-CoV-2 by stabilizing inactive Spike

Applications of molecular replacement to G protein-coupled receptors

Bivalent binding of a fully human IgG to the SARS-CoV-2 spike proteins reveals mechanisms of potent neutralization

Comparative host-coronavirus protein interaction networks reveal pan-viral disease mechanisms

Covalent agonists for studying G protein-coupled receptor activation

Crystal structure of the µ-opioid receptor bound to a morphinan antagonist

Engineering high-affinity PD-1 variants for optimized immunotherapy and immuno-PET imaging

Evaluation of SARS-CoV-2 serology assays reveals a range of test performance

G Protein-coupled Receptor Kinases of the GRK4 Protein Subfamily Phosphorylate Inactive G Protein-coupled Receptors (GPCRs).

Goniometer-based femtosecond crystallography with X-ray free electron lasers

Hedgehog pathway activation through nanobody-mediated conformational blockade of the Patched sterol conduit

High-density grids for efficient data collection from multiple crystals

Nanobodies to Study G Protein-Coupled Receptor Structure and Function

Propagation of conformational changes during μ-opioid receptor activation

Protein design and variant prediction using autoregressive generative models

Role of detergents in conformational exchange of a G protein-coupled receptor

SIGNAL TRANSDUCTION. Structural basis for nucleotide exchange in heterotrimeric G proteins

Selective G protein signaling driven by substance P-neurokinin receptor dynamics

Sortase ligation enables homogeneous GPCR phosphorylation to reveal diversity in β-arrestin coupling

Structural Insights into the Dynamic Process of β2-Adrenergic Receptor Signaling

Structural basis of odorant recognition by a human odorant receptor ⬇️

Structural insights into µ-opioid receptor activation

Structure of active β-arrestin-1 bound to a G-protein-coupled receptor phosphopeptide

Structure of hepcidin-bound ferroportin reveals iron homeostatic mechanisms

Structure of the δ-opioid receptor bound to naltrindole

Structure-based discovery of opioid analgesics with reduced side effects

The dynamic process of β(2)-adrenergic receptor activation

The role of ligands on the equilibria between functional states of a G protein-coupled receptor

The role of protein dynamics in GPCR function: insights from the β2AR and rhodopsin

Yeast surface display platform for rapid discovery of conformationally selective nanobodies.