Lista de obras - Anne S Robinson - Dominio Público Uruguay

Aggregates of α-chymotrypsinogen anneal to access more stable states

artículo científico publicado en 2013

Analysis of ER resident proteins in Saccharomyces cerevisiae: implementation of H/KDEL retrieval sequences.

artículo científico publicado en 2013

Analysis of adenosine A₂a receptor stability: effects of ligands and disulfide bonds.

artículo científico publicado en 2010

Analysis of unfolded protein response during single-chain antibody expression in Saccaromyces cerevisiae reveals different roles for BiP and PDI in folding.

artículo científico publicado en 2005

BiP clustering facilitates protein folding in the endoplasmic reticulum

artículo científico publicado en 2014

C-terminal hydrophobic interactions play a critical role in oligomeric assembly of the P22 tailspike trimer.

artículo científico publicado en 2003

Cassette series designed for live-cell imaging of proteins and high-resolution techniques in yeast.

artículo científico publicado en 2012

Coarse-grained model for colloidal protein interactions, B(22), and protein cluster formation

artículo científico publicado en 2013

Competing aggregation pathways for monoclonal antibodies

artículo científico publicado en 2014

Computational design and biophysical characterization of aggregation-resistant point mutations for γD crystallin illustrate a balance of conformational stability and intrinsic aggregation propensity.

artículo científico publicado en 2011

Conformational features of tau fibrils from Alzheimer's disease brain are faithfully propagated by unmodified recombinant protein

artículo científico publicado en 2013

Conformational stability as a design target to control protein aggregation.

artículo científico publicado en 2014

Conserved disulfide bond is not essential for the adenosine A2A receptor: Extracellular cysteines influence receptor distribution within the cell and ligand-binding recognition.

artículo científico publicado en 2014

Controllability analysis of protein glycosylation in CHO cells

artículo científico publicado en 2014

Controlling the Glycosylation Profile in mAbs Using Time-Dependent Media Supplementation

artículo científico publicado en 2017

Decreased Secretion and Unfolded Protein Response Upregulation ⬇️

artículo científico publicado el 1 de enero de 2011

Decreased protein expression and intermittent recoveries in BiP levels result from cellular stress during heterologous protein expression in Saccharomyces cerevisiae.

artículo científico publicado en 2002

Decreases in yeast expression yields of the human adenosine A2a receptor are a result of translational or post-translational events.

artículo científico publicado en 2004

Development of at-line assay to monitor charge variants of MAbs during production

artículo científico publicado en 2013

Dissociation of intermolecular disulfide bonds in P22 tailspike protein intermediates in the presence of SDS

artículo científico publicado en 2006

Disulphide-bonded intermediate on the folding and assembly pathway of a non-disulphide bonded protein

artículo científico publicado en 1997

Elevated expression temperature in a mesophilic host results in increased secretion of a hyperthermophilic enzyme and decreased cell stress.

artículo científico publicado en 2005

Enhanced insulin-like growth factor-I (IGF-I) cell association at reduced pH is dependent on IGF binding protein-3 (IGFBP-3) interaction.

artículo científico publicado en 2007

Exceptional total and functional yields of the human adenosine (A2a) receptor expressed in the yeast Saccharomyces cerevisiae.

artículo científico publicado en 2005

Functional Expression of Adenosine A3 Receptor in Yeast Utilizing a Chimera with the A2AR C-Terminus

artículo científico publicado en 2020

Heparan Sulfate Proteoglycans (HSPGs) Serve as the Mediator Between Monomeric Tau and Its Subsequent Intracellular ERK1/2 Pathway Activation

artículo científico publicado en 2022

Identification of manipulated variables for a glycosylation control strategy

artículo científico publicado en 2014

Identifying a robust design space for glycosylation during monoclonal antibody production

artículo científico publicado en 2016

Impact of purification conditions and history on A2A adenosine receptor activity: The role of CHAPS and lipids.

artículo científico publicado en 2016

Media supplementation for targeted manipulation of monoclonal antibody galactosylation and fucosylation

artículo científico publicado en 2020

Modulating non-native aggregation and electrostatic protein-protein interactions with computationally designed single-point mutations

artículo científico publicado en 2016

New tools for breaking barriers to GPCR expression in E. coli.

artículo científico publicado en 2011

P22 tailspike trimer assembly is governed by interchain redox associations.

artículo científico publicado en 2004

Pressure treatment of tailspike aggregates rapidly produces on-pathway folding intermediates.

artículo científico publicado en 2003

Protein disulfide isomerase overexpression increases secretion of foreign proteins in Saccharomyces cerevisiae

artículo científico publicado en 1994

Protein folding and secretion: mechanistic insights advancing recombinant protein production in S. cerevisiae.

artículo científico

Rapid refolding and polishing of single-chain antibodies from Escherichia coli inclusion bodies

artículo científico publicado en 2002

Recombinant G protein-coupled receptor expression in Saccharomyces cerevisiae for protein characterization.

artículo científico

Recombinant protein expression and purification: a comprehensive review of affinity tags and microbial applications

artículo científico publicado en 2012

Reduction of BiP levels decreases heterologous protein secretion in Saccharomyces cerevisiae.

artículo científico publicado en 1996

Refolding of G protein alpha subunits from inclusion bodies expressed in Escherichia coli.

artículo científico publicado en 2007

Role for cysteine residues in the in vivo folding and assembly of the phage P22 tailspike

artículo científico publicado en 2001

Spatial localisation of chaperone distribution in the endoplasmic reticulum of yeast ⬇️

artículo científico publicado el 1 de abril de 2012

Structure-function studies with G protein-coupled receptors as a paradigm for improving drug discovery and development of therapeutics.

artículo científico

The C-terminus of the P22 tailspike protein acts as an independent oligomerization domain for monomeric proteins.

artículo científico publicado en 2009

The Saccharomyces cerevisiae YFR041C/ERJ5 gene encoding a type I membrane protein with a J domain is required to preserve the folding capacity of the endoplasmic reticulum.

artículo científico publicado en 2007

The Specificity of Downstream Signaling for A<sub>1</sub> and A<sub>2A</sub>R Does Not Depend on the C-Terminus, Despite the Importance of This Domain in Downstream Signaling Strength

artículo científico publicado en 2020

The morphology and composition of cholesterol-rich micellar nanostructures determine transmembrane protein (GPCR) activity.

artículo científico publicado en 2011

Three amino acids that are critical to formation and stability of the P22 tailspike trimer.

artículo científico publicado en 2005

Toward rational design of protein detergent complexes: determinants of mixed micelles that are critical for the in vitro stabilization of a G-protein coupled receptor.

artículo científico publicado en 2011

Vulnerabilities in the tau network and the role of ultrasensitive points in tau pathophysiology

artículo científico publicado en 2010

Weak protein interactions and pH- and temperature-dependent aggregation of human Fc1.

artículo científico publicado en 2015

Lista de obras de Anne S Robinson

Aggregates of α-chymotrypsinogen anneal to access more stable states

Analysis of ER resident proteins in Saccharomyces cerevisiae: implementation of H/KDEL retrieval sequences.

Analysis of adenosine A₂a receptor stability: effects of ligands and disulfide bonds.

Analysis of unfolded protein response during single-chain antibody expression in Saccaromyces cerevisiae reveals different roles for BiP and PDI in folding.

BiP clustering facilitates protein folding in the endoplasmic reticulum

C-terminal hydrophobic interactions play a critical role in oligomeric assembly of the P22 tailspike trimer.

Cassette series designed for live-cell imaging of proteins and high-resolution techniques in yeast.

Coarse-grained model for colloidal protein interactions, B(22), and protein cluster formation

Competing aggregation pathways for monoclonal antibodies

Computational design and biophysical characterization of aggregation-resistant point mutations for γD crystallin illustrate a balance of conformational stability and intrinsic aggregation propensity.

Conformational features of tau fibrils from Alzheimer's disease brain are faithfully propagated by unmodified recombinant protein

Conformational stability as a design target to control protein aggregation.

Conserved disulfide bond is not essential for the adenosine A2A receptor: Extracellular cysteines influence receptor distribution within the cell and ligand-binding recognition.

Controllability analysis of protein glycosylation in CHO cells

Controlling the Glycosylation Profile in mAbs Using Time-Dependent Media Supplementation

Decreased Secretion and Unfolded Protein Response Upregulation ⬇️

Decreased protein expression and intermittent recoveries in BiP levels result from cellular stress during heterologous protein expression in Saccharomyces cerevisiae.

Decreases in yeast expression yields of the human adenosine A2a receptor are a result of translational or post-translational events.

Development of at-line assay to monitor charge variants of MAbs during production

Dissociation of intermolecular disulfide bonds in P22 tailspike protein intermediates in the presence of SDS

Disulphide-bonded intermediate on the folding and assembly pathway of a non-disulphide bonded protein

Elevated expression temperature in a mesophilic host results in increased secretion of a hyperthermophilic enzyme and decreased cell stress.

Enhanced insulin-like growth factor-I (IGF-I) cell association at reduced pH is dependent on IGF binding protein-3 (IGFBP-3) interaction.

Exceptional total and functional yields of the human adenosine (A2a) receptor expressed in the yeast Saccharomyces cerevisiae.

Functional Expression of Adenosine A3 Receptor in Yeast Utilizing a Chimera with the A2AR C-Terminus

Heparan Sulfate Proteoglycans (HSPGs) Serve as the Mediator Between Monomeric Tau and Its Subsequent Intracellular ERK1/2 Pathway Activation

Identification of manipulated variables for a glycosylation control strategy

Identifying a robust design space for glycosylation during monoclonal antibody production

Impact of purification conditions and history on A2A adenosine receptor activity: The role of CHAPS and lipids.

Media supplementation for targeted manipulation of monoclonal antibody galactosylation and fucosylation

Modulating non-native aggregation and electrostatic protein-protein interactions with computationally designed single-point mutations

New tools for breaking barriers to GPCR expression in E. coli.

P22 tailspike trimer assembly is governed by interchain redox associations.

Pressure treatment of tailspike aggregates rapidly produces on-pathway folding intermediates.

Protein disulfide isomerase overexpression increases secretion of foreign proteins in Saccharomyces cerevisiae

Protein folding and secretion: mechanistic insights advancing recombinant protein production in S. cerevisiae.

Rapid refolding and polishing of single-chain antibodies from Escherichia coli inclusion bodies

Recombinant G protein-coupled receptor expression in Saccharomyces cerevisiae for protein characterization.

Recombinant protein expression and purification: a comprehensive review of affinity tags and microbial applications

Reduction of BiP levels decreases heterologous protein secretion in Saccharomyces cerevisiae.

Refolding of G protein alpha subunits from inclusion bodies expressed in Escherichia coli.

Role for cysteine residues in the in vivo folding and assembly of the phage P22 tailspike

Spatial localisation of chaperone distribution in the endoplasmic reticulum of yeast ⬇️

Structure-function studies with G protein-coupled receptors as a paradigm for improving drug discovery and development of therapeutics.

The C-terminus of the P22 tailspike protein acts as an independent oligomerization domain for monomeric proteins.

The Saccharomyces cerevisiae YFR041C/ERJ5 gene encoding a type I membrane protein with a J domain is required to preserve the folding capacity of the endoplasmic reticulum.

The Specificity of Downstream Signaling for A<sub>1</sub> and A<sub>2A</sub>R Does Not Depend on the C-Terminus, Despite the Importance of This Domain in Downstream Signaling Strength

The morphology and composition of cholesterol-rich micellar nanostructures determine transmembrane protein (GPCR) activity.

Three amino acids that are critical to formation and stability of the P22 tailspike trimer.

Toward rational design of protein detergent complexes: determinants of mixed micelles that are critical for the in vitro stabilization of a G-protein coupled receptor.

Vulnerabilities in the tau network and the role of ultrasensitive points in tau pathophysiology

Weak protein interactions and pH- and temperature-dependent aggregation of human Fc1.