Lista de obras -

A brain-based pain facilitation mechanism contributes to painful diabetic polyneuropathy.

artículo científico publicado en 2018

A clinically relevant rodent model of the HIV antiretroviral drug stavudine induced painful peripheral neuropathy ⬇️

artículo científico publicado el 11 de enero de 2013

A comparison of RNA-seq and exon arrays for whole genome transcription profiling of the L5 spinal nerve transection model of neuropathic pain in the rat.

artículo científico publicado en 2014

A distinct subgroup of small DRG cells express GDNF receptor components and GDNF is protective for these neurons after nerve injury.

artículo científico publicado en 1998

A fovea for pain at the fingertips.

artículo científico publicado en 2013

A genome-wide association analysis identifies 16 novel susceptibility loci for carpal tunnel syndrome

artículo científico publicado en 2019

A novel SOD1-ALS mutation separates central and peripheral effects of mutant SOD1 toxicity

artículo científico publicado en 2014

A novel human pain insensitivity disorder caused by a point mutation in ZFHX2.

artículo científico publicado en 2017

A rodent model of HIV protease inhibitor indinavir induced peripheral neuropathy.

artículo científico publicado en 2016

Altered potassium channel distribution and composition in myelinated axons suppresses hyperexcitability following injury.

artículo científico publicado en 2016

Analysis of motor dysfunction in Down Syndrome reveals motor neuron degeneration.

artículo científico publicado en 2018

Anti-MuSK antibodies in a case of ocular myasthenia gravis.

artículo científico publicado en 2006

Artemin has potent neurotrophic actions on injured C-fibres.

artículo científico publicado en 2006

Autoimmune pain: an emerging concept

artículo científico publicado en 2012

Axonal neuregulin 1 is a rate limiting but not essential factor for nerve remyelination.

artículo científico publicado en 2013

Axonally derived neuregulin-1 is required for remyelination and regeneration after nerve injury in adulthood.

artículo científico publicado en 2011

Bace1 and Neuregulin-1 cooperate to control formation and maintenance of muscle spindles

artículo científico publicado en 2013

Botulinum toxin-A treatment reduces human mechanical pain sensitivity and mechanotransduction

artículo científico publicado en 2014

Brain-derived neurotrophic factor is an endogenous modulator of nociceptive responses in the spinal cord

artículo científico publicado en 1999

CXCL5 mediates UVB irradiation-induced pain

artículo científico publicado en 2011

Canomad presenting without ophthalmoplegia and responding to intravenous immunoglobulin

artículo científico publicado en 2011

Characterisation and mechanisms of bradykinin-evoked pain in man using iontophoresis.

artículo científico publicado en 2013

Characterisation of a peripheral neuropathic component of the rat monoiodoacetate model of osteoarthritis

artículo científico publicado en 2012

Chemokine expression in peripheral tissues from the monosodium iodoacetate model of chronic joint pain.

artículo científico publicado en 2013

Chronic non-freezing cold injury results in neuropathic pain due to a sensory neuropathy

artículo científico publicado en 2017

Circuitry and plasticity of the dorsal horn--toward a better understanding of neuropathic pain.

artículo científico publicado en 2015

Co-cultures with stem cell-derived human sensory neurons reveal regulators of peripheral myelination.

artículo científico publicado en 2017

Comprehensive analysis of Long non-coding RNA expression in dorsal root ganglion reveals cell type specificity and dysregulation following nerve injury

artículo científico publicado en 2019

Conduction failure following spinal cord injury: functional and anatomical changes from acute to chronic stages

artículo científico publicado en 2011

Crosstalk between the nociceptive and immune systems in host defence and disease

artículo científico publicado en 2015

Defining the Functional Role of Na1.7 in Human Nociception

artículo científico publicado en 2019

Development of MRC Centre MRI calf muscle fat fraction protocol as a sensitive outcome measure in Hereditary Sensory Neuropathy Type 1

scientific article published on 17 April 2019

Disruption of the Sensory System Affects Sterile Cutaneous Inflammation In Vivo

artículo científico publicado en 2019

Endogenous nerve growth factor regulates the sensitivity of nociceptors in the adult rat

scientific article published on 01 April 1998

Erratum: Corrigendum: Transcriptional regulator PRDM12 is essential for human pain perception

artículo científico publicado en 2015

Evaluation of tubulin polymerization and chronic inhibition of proteasome as citotoxicity mechanisms in bortezomib-induced peripheral neuropathy.

artículo científico publicado en 2013

Extracellular histone H1 is neurotoxic and drives a pro-inflammatory response in microglia

artículo científico publicado en 2013

Feasibility of Diffusion Tensor and Morphologic Imaging of Peripheral Nerves at Ultra-High Field Strength

artículo científico publicado en 2018

Following nerve injury neuregulin-1 drives microglial proliferation and neuropathic pain via the MEK/ERK pathway.

artículo científico publicado en 2011

Genes, molecules and patients—Emerging topics to guide clinical pain research ⬇️

artículo científico publicado el 13 de marzo de 2013

Germline selection shapes human mitochondrial DNA diversity

scientific article published on 23 May 2019

Handedness, language areas and neuropsychiatric diseases: insights from brain imaging and genetics

artículo científico publicado en 2019

Hepatocyte growth factor, colony-stimulating factor 1, CD40, and 11 other inflammation-related proteins are associated with pain in diabetic neuropathy: exploration and replication serum data from the Pain in Neuropathy Study

artículo científico publicado en 2022

Hereditary sensory neuropathy type 1-associated deoxysphingolipids cause neurotoxicity, acute calcium handling abnormalities and mitochondrial dysfunction in vitro

scientific article published on 18 May 2018

Identification of patients with neuropathic pain using electronic primary care records

artículo científico publicado en 2011

Imaging the neural correlates of neuropathic pain and pleasurable relief associated with inherited erythromelalgia in a single subject with quantitative arterial spin labelling.

artículo científico publicado en 2012

Immune or Genetic-Mediated Disruption of CASPR2 Causes Pain Hypersensitivity Due to Enhanced Primary Afferent Excitability

artículo científico publicado en 2018

Informed drug choices for neuropathic pain

artículo científico publicado en 2015

Intermediate Charcot-Marie-Tooth disease due to a novel Trp101Stop myelin protein zero mutation associated with debilitating neuropathic pain.

artículo científico publicado en 2012

Membrane metallo-endopeptidase is dispensable for repair after nerve injury

scientific article published on 24 July 2019

Mexiletine as a treatment for primary erythromelalgia: normalization of biophysical properties of mutant L858F NaV 1.7 sodium channels.

artículo científico publicado en 2014

Microdeletion in a FAAH pseudogene identified in a patient with high anandamide concentrations and pain insensitivity

scientific article published on 28 March 2019

Morphological and functional properties distinguish the substance P and gastrin-releasing peptide subsets of excitatory interneuron in the spinal cord dorsal horn

scientific article published on 01 February 2019

NGF but not NT-3 or BDNF prevents the A fiber sprouting into lamina II of the spinal cord that occurs following axotomy

artículo científico publicado en 1996

Negative Neurodynamic Tests Do Not Exclude Neural Dysfunction in Patients With Entrapment Neuropathies.

artículo científico publicado en 2016

Nerve Growth Factor and Pain Mechanisms

artículo científico publicado en 2017

Nerve growth factor treatment increases brain-derived neurotrophic factor selectively in TrkA-expressing dorsal root ganglion cells and in their central terminations within the spinal cord

artículo científico publicado en 1997

Neuregulin-1 controls an endogenous repair mechanism after spinal cord injury.

artículo científico publicado en 2016

Neuroinflammation and the generation of neuropathic pain.

artículo científico

Neuropathic pain

Neuropathic pain drives anxiety behavior in mice, results consistent with anxiety levels in diabetic neuropathy patients.

artículo científico publicado en 2018

Neutralization of endogenous NGF prevents the sensitization of nociceptors supplying inflamed skin

artículo científico publicado en 1999

New Horizons in Diabetic Neuropathy: Mechanisms, Bioenergetics, and Pain

artículo científico publicado en 2017

Null mutation in SCN9A in which noxious stimuli can be detected in the absence of pain.

artículo científico publicado en 2014

Pain and the immune system: emerging concepts of IgG-mediated autoimmune pain and immunotherapies

scientific article published on 17 September 2018

Painful and painless channelopathies.

artículo científico

Pathogenic mechanisms in inflammatory and paraproteinaemic peripheral neuropathies

artículo científico publicado en 2014

Persistent microglial activation and synaptic loss with behavioral abnormalities in mouse offspring exposed to CASPR2-antibodies in utero.

artículo científico publicado en 2017

Postnatal changes in the expression of the trkA high-affinity NGF receptor in primary sensory neurons

artículo científico publicado en 1996

Postsynaptic effects of long-range afferents in distant segments caudal to their entry point in rat spinal cord under the influence of picrotoxin or strychnine

artículo científico publicado en 1994

Potent analgesic effects of GDNF in neuropathic pain states.

artículo científico publicado en 2000

Preoperative ultraviolet B inflammation in skin: Modelling individual differences in acute postoperative pain and neuro-immune interactions

artículo científico publicado en 2017

RalGTPases contribute to Schwann cell repair after nerve injury via regulation of process formation

scientific article published on 14 June 2019

Rare Nav1.7 variants associated with painful diabetic peripheral neuropathy.

artículo científico publicado en 2017

Recessive dystrophic epidermolysis bullosa results in painful small fibre neuropathy

artículo científico publicado en 2017

Relationship between dry eye symptoms and pain sensitivity.

artículo científico publicado en 2013

Reply: Non-freezing cold injury: a multi-faceted syndrome.

artículo científico publicado en 2018

Sensory neuron fate is developmentally perturbed by Gars mutations causing human neuropathy

Sensory processing of deep tissue nociception in the rat spinal cord and thalamic ventrobasal complex.

artículo científico publicado en 2017

Sustained MAPK/ERK Activation in Adult Schwann Cells Impairs Nerve Repair.

artículo científico publicado en 2017

Synthesis of lipid mediators during UVB-induced inflammatory hyperalgesia in rats and mice

artículo científico publicado en 2013

Systemic inflammatory markers in neuropathic pain, nerve injury, and recovery

artículo científico publicado en 2022

TRP-channels as key integrators of lipid pathways in nociceptive neurons.

artículo científico publicado en 2013

The Genetics of Neuropathic Pain from Model Organisms to Clinical Application

artículo científico publicado en 2019

The Novel Activity of Carbamazepine as an Activation Modulator Extends from NaV1.7 Mutations to the NaV1.8-S242T Mutant Channel from a Patient with Painful Diabetic Neuropathy

scientific article published on 22 August 2018

The Role of Neuregulin-1 In the Response To Nerve Injury ⬇️

artículo científico publicado el 1 de noviembre de 2011

The Role of Voltage-Gated Sodium Channels in Pain Signaling

artículo científico publicado en 2019

The biological effects of endogenous nerve growth factor on adult sensory neurons revealed by a trkA-IgG fusion molecule

scientific article published on 01 August 1995

The clinical approach to small fibre neuropathy and painful channelopathy

artículo científico publicado en 2014

The glial cell line-derived neurotrophic factor family receptor components are differentially regulated within sensory neurons after nerve injury.

artículo científico

The mechanisms of microgliosis and pain following peripheral nerve injury.

artículo científico publicado en 2011

The relationship of nerve fibre pathology to sensory function in entrapment neuropathy.

artículo científico publicado en 2014

The role of the immune system in the generation of neuropathic pain ⬇️

artículo científico publicado el 1 de julio de 2012

The use of nerve and muscle biopsy in the diagnosis of vasculitis: a 5 year retrospective study.

artículo científico publicado en 2008

The world through tinted glasses

scientific article published on 01 July 2004

Trk receptor signaling and sensory neuron fate are perturbed in human neuropathy caused by Gars mutations.

artículo científico publicado en 2017

Tumefactive neuro-Behcet disease

scientific article published on 01 August 2004

Using an engineered glutamate-gated chloride channel to silence sensory neurons and treat neuropathic pain at the source

artículo científico publicado en 2017

Using stratified medicine to understand, diagnose, and treat neuropathic pain

scientific article published on 01 September 2018

Variable phenotypes are associated with PMP22 missense mutations

scientific article published on 30 December 2010

Voltage-gated sodium channel mutations and painful neuropathy: Na(v)1.9 joins the family

artículo científico publicado en 2014

Whippits, nitrous oxide and the dangers of legal highs

artículo científico publicado en 2015

trkA, CGRP and IB4 expression in retrogradely labelled cutaneous and visceral primary sensory neurones in the rat.

artículo científico publicado en 1996

α2δ-1 gene deletion affects somatosensory neuron function and delays mechanical hypersensitivity in response to peripheral nerve damage

artículo científico publicado en 2013

Lista de obras de

A brain-based pain facilitation mechanism contributes to painful diabetic polyneuropathy.

A clinically relevant rodent model of the HIV antiretroviral drug stavudine induced painful peripheral neuropathy ⬇️

A comparison of RNA-seq and exon arrays for whole genome transcription profiling of the L5 spinal nerve transection model of neuropathic pain in the rat.

A distinct subgroup of small DRG cells express GDNF receptor components and GDNF is protective for these neurons after nerve injury.

A fovea for pain at the fingertips.

A genome-wide association analysis identifies 16 novel susceptibility loci for carpal tunnel syndrome

A novel SOD1-ALS mutation separates central and peripheral effects of mutant SOD1 toxicity

A novel human pain insensitivity disorder caused by a point mutation in ZFHX2.

A rodent model of HIV protease inhibitor indinavir induced peripheral neuropathy.

Altered potassium channel distribution and composition in myelinated axons suppresses hyperexcitability following injury.

Analysis of motor dysfunction in Down Syndrome reveals motor neuron degeneration.

Anti-MuSK antibodies in a case of ocular myasthenia gravis.

Artemin has potent neurotrophic actions on injured C-fibres.

Autoimmune pain: an emerging concept

Axonal neuregulin 1 is a rate limiting but not essential factor for nerve remyelination.

Axonally derived neuregulin-1 is required for remyelination and regeneration after nerve injury in adulthood.

Bace1 and Neuregulin-1 cooperate to control formation and maintenance of muscle spindles

Botulinum toxin-A treatment reduces human mechanical pain sensitivity and mechanotransduction

Brain-derived neurotrophic factor is an endogenous modulator of nociceptive responses in the spinal cord

CXCL5 mediates UVB irradiation-induced pain

Canomad presenting without ophthalmoplegia and responding to intravenous immunoglobulin

Characterisation and mechanisms of bradykinin-evoked pain in man using iontophoresis.

Characterisation of a peripheral neuropathic component of the rat monoiodoacetate model of osteoarthritis

Chemokine expression in peripheral tissues from the monosodium iodoacetate model of chronic joint pain.

Chronic non-freezing cold injury results in neuropathic pain due to a sensory neuropathy

Circuitry and plasticity of the dorsal horn--toward a better understanding of neuropathic pain.

Co-cultures with stem cell-derived human sensory neurons reveal regulators of peripheral myelination.

Comprehensive analysis of Long non-coding RNA expression in dorsal root ganglion reveals cell type specificity and dysregulation following nerve injury

Conduction failure following spinal cord injury: functional and anatomical changes from acute to chronic stages

Crosstalk between the nociceptive and immune systems in host defence and disease

Defining the Functional Role of Na1.7 in Human Nociception

Development of MRC Centre MRI calf muscle fat fraction protocol as a sensitive outcome measure in Hereditary Sensory Neuropathy Type 1

Disruption of the Sensory System Affects Sterile Cutaneous Inflammation In Vivo

Endogenous nerve growth factor regulates the sensitivity of nociceptors in the adult rat

Erratum: Corrigendum: Transcriptional regulator PRDM12 is essential for human pain perception

Evaluation of tubulin polymerization and chronic inhibition of proteasome as citotoxicity mechanisms in bortezomib-induced peripheral neuropathy.

Extracellular histone H1 is neurotoxic and drives a pro-inflammatory response in microglia

Feasibility of Diffusion Tensor and Morphologic Imaging of Peripheral Nerves at Ultra-High Field Strength

Following nerve injury neuregulin-1 drives microglial proliferation and neuropathic pain via the MEK/ERK pathway.

Genes, molecules and patients—Emerging topics to guide clinical pain research ⬇️

Germline selection shapes human mitochondrial DNA diversity

Handedness, language areas and neuropsychiatric diseases: insights from brain imaging and genetics

Hepatocyte growth factor, colony-stimulating factor 1, CD40, and 11 other inflammation-related proteins are associated with pain in diabetic neuropathy: exploration and replication serum data from the Pain in Neuropathy Study

Hereditary sensory neuropathy type 1-associated deoxysphingolipids cause neurotoxicity, acute calcium handling abnormalities and mitochondrial dysfunction in vitro

Identification of patients with neuropathic pain using electronic primary care records

Imaging the neural correlates of neuropathic pain and pleasurable relief associated with inherited erythromelalgia in a single subject with quantitative arterial spin labelling.

Immune or Genetic-Mediated Disruption of CASPR2 Causes Pain Hypersensitivity Due to Enhanced Primary Afferent Excitability

Informed drug choices for neuropathic pain

Intermediate Charcot-Marie-Tooth disease due to a novel Trp101Stop myelin protein zero mutation associated with debilitating neuropathic pain.

Membrane metallo-endopeptidase is dispensable for repair after nerve injury

Mexiletine as a treatment for primary erythromelalgia: normalization of biophysical properties of mutant L858F NaV 1.7 sodium channels.

Microdeletion in a FAAH pseudogene identified in a patient with high anandamide concentrations and pain insensitivity

Morphological and functional properties distinguish the substance P and gastrin-releasing peptide subsets of excitatory interneuron in the spinal cord dorsal horn

NGF but not NT-3 or BDNF prevents the A fiber sprouting into lamina II of the spinal cord that occurs following axotomy

Negative Neurodynamic Tests Do Not Exclude Neural Dysfunction in Patients With Entrapment Neuropathies.

Nerve Growth Factor and Pain Mechanisms

Nerve growth factor treatment increases brain-derived neurotrophic factor selectively in TrkA-expressing dorsal root ganglion cells and in their central terminations within the spinal cord

Neuregulin-1 controls an endogenous repair mechanism after spinal cord injury.

Neuroinflammation and the generation of neuropathic pain.

Neuropathic pain

Neuropathic pain drives anxiety behavior in mice, results consistent with anxiety levels in diabetic neuropathy patients.

Neutralization of endogenous NGF prevents the sensitization of nociceptors supplying inflamed skin

New Horizons in Diabetic Neuropathy: Mechanisms, Bioenergetics, and Pain

Null mutation in SCN9A in which noxious stimuli can be detected in the absence of pain.

Pain and the immune system: emerging concepts of IgG-mediated autoimmune pain and immunotherapies

Painful and painless channelopathies.

Pathogenic mechanisms in inflammatory and paraproteinaemic peripheral neuropathies

Persistent microglial activation and synaptic loss with behavioral abnormalities in mouse offspring exposed to CASPR2-antibodies in utero.

Postnatal changes in the expression of the trkA high-affinity NGF receptor in primary sensory neurons

Postsynaptic effects of long-range afferents in distant segments caudal to their entry point in rat spinal cord under the influence of picrotoxin or strychnine

Potent analgesic effects of GDNF in neuropathic pain states.

Preoperative ultraviolet B inflammation in skin: Modelling individual differences in acute postoperative pain and neuro-immune interactions

RalGTPases contribute to Schwann cell repair after nerve injury via regulation of process formation

Rare Nav1.7 variants associated with painful diabetic peripheral neuropathy.

Recessive dystrophic epidermolysis bullosa results in painful small fibre neuropathy

Relationship between dry eye symptoms and pain sensitivity.

Reply: Non-freezing cold injury: a multi-faceted syndrome.

Sensory neuron fate is developmentally perturbed by Gars mutations causing human neuropathy

Sensory processing of deep tissue nociception in the rat spinal cord and thalamic ventrobasal complex.