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A Comprehensive Human Gastric Cancer Organoid Biobank Captures Tumor Subtype Heterogeneity and Enables Therapeutic Screening

artículo científico publicado en 2018

A simplified Bcl-2 network model reveals quantitative determinants of cell-to-cell variation in sensitivity to anti-mitotic chemotherapeutics.

artículo científico publicado en 2016

Alocasia cucullata exhibits strong antitumor effect in vivo by activating antitumor immunity

artículo científico publicado en 2013

An indirubin derivative, E804, exhibits potent angiosuppressive activity

scientific article published on 09 December 2011

Application of single-molecule spectroscopy in studying enzyme kinetics and mechanism.

artículo científico publicado en 2008

Cell death response to anti-mitotic drug treatment in cell culture, mouse tumor model and the clinic

artículo científico publicado en 2017

Cell death when the SAC is out of commission

scientific article published on 01 June 2010

Cell type variation in responses to antimitotic drugs that target microtubules and kinesin-5.

artículo científico publicado en 2008

Cell type-dependent bimodal p53 activation engenders a dynamic mechanism of chemoresistance

artículo científico publicado en 2018

Comparative in vitro cytotoxicity study on uncoated magnetic nanoparticles: effects on cell viability, cell morphology, and cellular uptake.

artículo científico publicado en 2012

DNA damage strength modulates a bimodal switch of p53 dynamics for cell-fate control

artículo científico publicado en 2013

Evidence that mitotic exit is a better cancer therapeutic target than spindle assembly.

artículo científico publicado en 2009

Fas ligand and lytic granule differentially control cytotoxic dynamics of natural killer cell against cancer target

artículo científico publicado en 2016

Influence of engineered surface on cell directionality and motility

artículo científico publicado en 2014

Is inflammatory micronucleation the key to a successful anti-mitotic cancer drug?

artículo científico publicado en 2017

Lysyl oxidase-like 2 is critical to tumor microenvironment and metastatic niche formation in hepatocellular carcinoma.

artículo científico publicado en 2014

MiR-200b/200c/429 subfamily negatively regulates Rho/ROCK signaling pathway to suppress hepatocellular carcinoma metastasis

artículo científico publicado en 2015

Navitoclax (ABT-263) accelerates apoptosis during drug-induced mitotic arrest by antagonizing Bcl-xL.

artículo científico publicado en 2011

Network dynamics-based cancer panel stratification for systemic prediction of anticancer drug response.

artículo científico publicado en 2017

Post-slippage multinucleation renders cytotoxic variation in anti-mitotic drugs that target the microtubules or mitotic spindle

artículo científico publicado en 2014

Quantitative live imaging of cancer and normal cells treated with Kinesin-5 inhibitors indicates significant differences in phenotypic responses and cell fate

artículo científico publicado en 2008

Rac1/ROCK-driven membrane dynamics promote natural killer cell cytotoxicity via granzyme-induced necroptosis

artículo científico publicado en 2021

Resonance versus linear responses to alternating electric fields induce mechanistically distinct mammalian cell death.

artículo científico publicado en 2013

Stochastic competition between mechanistically independent slippage and death pathways determines cell fate during mitotic arrest

artículo científico publicado en 2010