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Lista de obras de Robert P Giugliano

2004 ACC/AHA guideline for the management of patients with STEMI: the implications for clinicians

artículo científico publicado en 2005

A Randomized, Blinded Study of Two Doses of Novastan(R) (Brand of Argatroban) Versus Heparin as Adjunctive Therapy to Recombinant Tissue Plasminogen Activator (Accelerated Administration) in Acute Myocardial Infarction: Rationale and Design of the M

artículo científico publicado en 1998

A multicenter, randomized study of argatroban versus heparin as adjunct to tissue plasminogen activator (TPA) in acute myocardial infarction: myocardial infarction with novastan and TPA (MINT) study

artículo científico publicado en 1999

A novel approach indirectly comparing benefit-risk balance across anti-thrombotic therapies in patients with atrial fibrillation

artículo científico publicado en 2015

A novel risk prediction score in atrial fibrillation for a net clinical outcome from the ENGAGE AF-TIMI 48 randomized clinical trial

artículo científico publicado en 2017

A polygenic risk score predicts atrial fibrillation in cardiovascular disease

scientific article published in 2022

A review of low-density lipoprotein cholesterol, treatment strategies, and its impact on cardiovascular disease morbidity and mortality

artículo científico publicado en 2016

A strategy of using enoxaparin as adjunctive antithrombin therapy reduces death and recurrent myocardial infarction in patients who achieve early ST-segment resolution after fibrinolytic therapy: the ExTRACT-TIMI 25 ECG study

artículo científico publicado en 2007

AMG 145, a monoclonal antibody against PCSK9, facilitates achievement of national cholesterol education program-adult treatment panel III low-density lipoprotein cholesterol goals among high-risk patients: an analysis from the LAPLACE-TIMI 57 trial

artículo científico publicado en 2013

AMG145, a monoclonal antibody against proprotein convertase subtilisin kexin type 9, significantly reduces lipoprotein(a) in hypercholesterolemic patients receiving statin therapy: an analysis from the LDL-C Assessment with Proprotein Convertase Sub

artículo científico publicado en 2013

Abciximab facilitates the rate and extent of thrombolysis: results of the thrombolysis in myocardial infarction (TIMI) 14 trial. The TIMI 14 Investigators

scientific article published on 01 June 1999

Abciximab improves both epicardial flow and myocardial reperfusion in ST-elevation myocardial infarction. Observations from the TIMI 14 trial

scientific article published on 01 January 2000

Achievement of dual low-density lipoprotein cholesterol and high-sensitivity C-reactive protein targets more frequent with the addition of ezetimibe to simvastatin and associated with better outcomes in IMPROVE-IT.

artículo científico

Achievement of guideline-concordant care and in-hospital outcomes in patients with coronary artery disease in teaching and nonteaching hospitals: results from the Get With The Guidelines-Coronary Artery Disease program

artículo científico publicado en 2012

Adjunctive pharmacologic therapy in percutaneous coronary intervention: part I antiplatelet therapy.

artículo científico publicado en 2011

Adjunctive pharmacologic therapy in percutaneous coronary intervention: part II anticoagulant therapy.

artículo científico publicado en 2011

Adjunctive use of anticoagulants at the time of percutaneous coronary intervention in patients with an acute coronary syndrome treated with fondaparinux: a multinational retrospective review.

artículo científico publicado en 2017

Advances in the field of proprotein convertase subtilisin kexin type 9 inhibitors.

artículo científico publicado en 2016

Age, treatment, and outcomes in high-risk non-ST-segment elevation acute coronary syndrome patients: insights from the EARLY ACS trial

artículo científico publicado en 2012

An update on the IMProved reduction of outcomes: Vytorin Efficacy International Trial (IMPROVE-IT) design

artículo científico publicado en 2010

Angiographic and clinical outcomes among patients with acute coronary syndromes presenting with isolated anterior ST-segment depression: a TRITON-TIMI 38 (Trial to Assess Improvement in Therapeutic Outcomes by Optimizing Platelet Inhibition With Pra

artículo científico publicado en 2010

Angiographic and clinical outcomes associated with direct versus conventional stenting among patients treated with fibrinolytic therapy for ST-elevation acute myocardial infarction

artículo científico publicado en 2005

Angiographic outcomes with early eptifibatide therapy in non-ST-segment elevation acute coronary syndrome (from the EARLY ACS Trial).

artículo científico publicado en 2014

Angiographic perfusion score: an angiographic variable that integrates both epicardial and tissue level perfusion before and after facilitated percutaneous coronary intervention in acute myocardial infarction

artículo científico publicado en 2004

Antibiotic treatment of Chlamydia pneumoniae after acute coronary syndrome

scientific article published on April 2005

Anticoagulation After Heart Valve Replacement or Transcatheter Valve Implantation.

artículo científico publicado en 2016

Anticoagulation-related nephropathy

artículo científico

Antiplatelet and Anticoagulation Treatment in Patients With Non-ST-Segment Elevation Acute Coronary Syndrome: Comparison of the Updated North American and European Guidelines

artículo científico

Antiplatelet therapy in percutaneous coronary intervention: integration of prasugrel into clinical practice.

artículo científico publicado en 2009

Antithrombotics in acute coronary syndromes

artículo científico publicado en 2009

Antithrombotics in acute coronary syndromes: updates from the past year.

artículo científico publicado en 2010

Are PCSK9 Inhibitors the Next Breakthrough in the Cardiovascular Field?

artículo científico publicado en 2015

Association Between Circulating Baseline Proprotein Convertase Subtilisin Kexin Type 9 Levels and Efficacy of Evolocumab

artículo científico publicado en 2017

Association Between Lowering LDL-C and Cardiovascular Risk Reduction Among Different Therapeutic Interventions: A Systematic Review and Meta-analysis

artículo científico publicado en 2016

Association between angiographic complications and clinical outcomes among patients with acute coronary syndrome undergoing percutaneous coronary intervention: an EARLY ACS (Early Glycoprotein IIb/IIIa Inhibition in Non-ST-Segment Elevation Acute Co

scientific article published on 01 September 2012

Association between bleeding and mortality among women and men with high-risk acute coronary syndromes: insights from the Early versus Delayed, Provisional Eptifibatide in Acute Coronary Syndromes (EARLY ACS) trial

artículo científico publicado en 2013

Association between edoxaban dose, concentration, anti-Factor Xa activity, and outcomes: an analysis of data from the randomised, double-blind ENGAGE AF-TIMI 48 trial

artículo científico publicado en 2015

Association of a history of systemic hypertension with mortality, thrombotic, and bleeding complications following non-ST-segment elevation acute coronary syndrome

artículo científico publicado en 2006

Association of a negative residual stenosis following rescue/adjunctive percutaneous coronary intervention with impaired myocardial perfusion and adverse outcomes among ST-segment elevation myocardial infarction patients

artículo científico publicado en 2005

Association of a pulsatile blood flow pattern on coronary arteriography and short-term clinical outcomes in acute myocardial infarction

artículo científico publicado en 2004

Association of creatinine and creatinine clearance on presentation in acute myocardial infarction with subsequent mortality

artículo científico publicado en 2003

Association of culprit lesion calcium with angiographic and clinical outcomes in patients with ST-elevation myocardial infarction treated with fibrinolytic therapy

artículo científico publicado en 2005

Association of duration of symptoms at presentation with angiographic and clinical outcomes after fibrinolytic therapy in patients with ST-segment elevation myocardial infarction

scientific article published on 01 September 2004

Association of epicardial and tissue-level reperfusion with left ventricular end-diastolic pressures in ST-elevation myocardial infarction

scientific article published on 01 June 2004

Association of glomerular filtration rate on presentation with subsequent mortality in non-ST-segment elevation acute coronary syndrome; observations in 13,307 patients in five TIMI trials

artículo científico publicado en 2004

Association of hemoglobin levels with clinical outcomes in acute coronary syndromes

scientific article published on 11 April 2005

Association of metabolic syndrome and its individual components with outcomes among patients with high-risk non-ST-segment elevation acute coronary syndromes

artículo científico publicado en 2014

Association of platelet count with residual thrombus in the myocardial infarct-related coronary artery among patients treated with fibrinolytic therapy for ST-segment elevation acute myocardial infarction

artículo científico publicado en 2004

Association of smoking with improved myocardial perfusion and the angiographic characterization of myocardial tissue perfusion after fibrinolytic therapy for ST-segment elevation myocardial infarction

artículo científico publicado en 2005

Association of the timing of ST-segment resolution with TIMI myocardial perfusion grade in acute myocardial infarction

artículo científico publicado en 2004

Association of unstable angina guideline care with improved survival.

artículo científico publicado en 2000

Atherothrombotic Risk Stratification and Ezetimibe for Secondary Prevention

artículo científico publicado en 2017

Atrial Fibrillation, Type 2 Diabetes, and Non-Vitamin K Antagonist Oral Anticoagulants: A Review.

artículo científico publicado en 2017

Atrial fibrillation and prior MI: searching for balance in ischaemic and bleeding events in patients treated with factor-specific anticoagulants.

artículo científico publicado en 2013

Atrial fibrillation and the 'other drug problem': reducing non-adherence with technology.

artículo científico publicado en 2013

Availability of on-site catheterization and clinical outcomes in patients receiving fibrinolysis for ST-elevation myocardial infarction

artículo científico publicado en 2001

Baseline low-density lipoprotein cholesterol is an important predictor of the benefit of intensive lipid-lowering therapy: a PROVE IT-TIMI 22 (Pravastatin or Atorvastatin Evaluation and Infection Therapy-Thrombolysis In Myocardial Infarction 22) ana

artículo científico publicado en 2008

Baseline troponin in acute coronary syndromes managed invasively

artículo científico publicado en 2004

Benefit of Adding Ezetimibe to Statin Therapy on Cardiovascular Outcomes and Safety in Patients With Versus Without Diabetes Mellitus: Results From IMPROVE-IT (Improved Reduction of Outcomes: Vytorin Efficacy International Trial).

artículo científico publicado en 2017

Biomarkers and Clinical Cardiovascular Outcomes With Ezetimibe in the IMPROVE-IT Trial

artículo científico publicado en 2019

Bridging therapy after recent stent implantation: case report and review of data.

artículo científico publicado en 2011

Caeteris paribus - all things being equal

scientific article published on 01 December 2001

Can we predict outcomes in atrial fibrillation?

artículo científico

Cardiac troponin after percutaneous coronary intervention and 1-year mortality in non-ST-segment elevation acute coronary syndrome using systematic evaluation of biomarker trends

artículo científico

Cardiovascular Biomarker Score and Clinical Outcomes in Patients With Atrial Fibrillation: A Subanalysis of the ENGAGE AF-TIMI 48 Randomized Clinical Trial

artículo científico

Cardiovascular Risk Reduction in Patients with Nonalcoholic Fatty Liver Disease: The Potential Role of Ezetimibe.

artículo científico publicado en 2016

Cardiovascular safety and efficacy of the PCSK9 inhibitor evolocumab in patients with and without diabetes and the effect of evolocumab on glycaemia and risk of new-onset diabetes: a prespecified analysis of the FOURIER randomised controlled trial.

artículo científico publicado en 2017

Cardioversion of Atrial Fibrillation in ENGAGE AF-TIMI 48.

artículo científico publicado en 2016

Care concordant with guidelines predicts decreased long-term mortality in patients with unstable angina pectoris and non-ST-elevation myocardial infarction.

artículo científico publicado en 2004

Cerebrovascular events in 21 105 patients with atrial fibrillation randomized to edoxaban versus warfarin: Effective Anticoagulation with Factor Xa Next Generation in Atrial Fibrillation-Thrombolysis in Myocardial Infarction 48.

artículo científico

Cholesterol levels and the association of statins with in-hospital mortality of myocardial infarction patients insights from a Chilean registry of myocardial infarction.

artículo científico publicado en 2013

Chronic anticoagulation in non-valvular atrial fibrillation: Where things stand

artículo científico publicado en 2016

Circadian variation in patient characteristics and outcomes in ST-segment elevation myocardial infarction

artículo científico publicado en 2012

Circadian variation of stent thrombosis and the effect of more robust platelet inhibition: a post hoc analysis of the TRITON-TIMI 38 trial

artículo científico publicado en 2013

Clinical Application of a Novel Genetic Risk Score for Ischemic Stroke in Patients with Cardiometabolic Disease

artículo científico publicado en 2020

Clinical Benefit of Evolocumab by Severity and Extent of Coronary Artery Disease: Analysis From FOURIER

artículo científico publicado en 2018

Clinical Efficacy and Safety of Evolocumab in High-Risk Patients Receiving a Statin: Secondary Analysis of Patients With Low LDL Cholesterol Levels and in Those Already Receiving a Maximal-Potency Statin in a Randomized Clinical Trial.

artículo científico publicado en 2017

Clinical benefits of evolocumab appear less than hoped - Authors' reply

artículo científico publicado en 2018

Clinical efficacy and safety of achieving very low LDL-cholesterol concentrations with the PCSK9 inhibitor evolocumab: a prespecified secondary analysis of the FOURIER trial.

artículo científico

Clinical events after interruption of anticoagulation in patients with atrial fibrillation: An analysis from the ENGAGE AF-TIMI 48 trial

artículo científico publicado en 2018

Clinical implications and correlates of Q waves in patients with ST-elevation myocardial infarction treated with fibrinolysis: observations from the CLARITY-TIMI 28 trial.

artículo científico publicado en 2014

Clinical problem-solving. When past is prologue.

artículo científico publicado en 2009

Cognitive Function in a Randomized Trial of Evolocumab

artículo científico publicado en 2017

Combination reperfusion therapy with abciximab and reduced dose reteplase: results from TIMI 14. The Thrombolysis in Myocardial Infarction (TIMI) 14 Investigators

artículo científico publicado en 2000

Combination reperfusion therapy with eptifibatide and reduced-dose tenecteplase for ST-elevation myocardial infarction: results of the integrilin and tenecteplase in acute myocardial infarction (INTEGRITI) Phase II Angiographic Trial

artículo científico publicado en 2003

Combined assessment of thrombolysis in myocardial infarction flow grade, myocardial perfusion grade, and ST-segment resolution to evaluate epicardial and myocardial reperfusion

artículo científico publicado en 2004

Comparison of Argatroban and Hirudin for the Reperfusion of Thrombotic Arterial Occlusion by Tissue Plasminogen Activator

artículo científico publicado en 1998

Comparison of LDL-C Reduction Using Different Evolocumab Doses and Intervals: Biological Insights and Treatment Implications

artículo científico publicado en 2018

Comparison of Low-Density Lipoprotein Cholesterol Assessment by Martin/Hopkins Estimation, Friedewald Estimation, and Preparative Ultracentrifugation: Insights From the FOURIER Trial.

artículo científico publicado en 2018

Comparison of ST-segment resolution with combined fibrinolytic and glycoprotein IIb/IIIa inhibitor therapy versus fibrinolytic alone (data from four clinical trials).

artículo científico publicado en 2005

Comparison of a 60- versus 90-minute determination of ST-segment resolution after thrombolytic therapy for acute myocardial infarction. In TIME-II Investigators. Intravenous nPA for Treatment of Infarcting Myocardium Early-II

artículo científico publicado en 2000

Comparison of the efficacy and safety of new oral anticoagulants with warfarin in patients with atrial fibrillation: a meta-analysis of randomised trials

artículo científico publicado en 2013

Comparison of the phase III clinical trial designs of novel oral anticoagulants versus warfarin for the treatment of nonvalvular atrial fibrillation: implications for clinical practice.

artículo científico

Comparison of the prognosis of spontaneous and percutaneous coronary intervention-related myocardial infarction.

artículo científico publicado en 2012

Competing Risks of Cardiovascular Versus Noncardiovascular Death During Long-Term Follow-Up After Acute Coronary Syndromes

artículo científico publicado en 2017

Complementary prognostic values of ST segment deviation and Thrombolysis In Myocardial Infarction (TIMI) risk score in non-ST elevation acute coronary syndromes: Insights from the Platelet Receptor Inhibition in Ischemic Syndrome Management in Patie

artículo científico publicado en 2009

Concomitant Use of Single Antiplatelet Therapy With Edoxaban or Warfarin in Patients With Atrial Fibrillation: Analysis From the ENGAGE AF-TIMI48 Trial

artículo científico publicado en 2016

Coronary artery stents: advances in technology.

artículo científico publicado en 2014

Cost-Effectiveness of Edoxaban vs. Warfarin in Patients with Atrial Fibrillation Based on Results of the ENGAGE AF - TIMI 48 Trial: Taiwanese Perspective

artículo científico publicado en 2017

Cost-effectiveness of Evolocumab Therapy for Reducing Cardiovascular Events in Patients With Atherosclerotic Cardiovascular Disease.

artículo científico publicado en 2017

Cost-effectiveness of edoxaban vs warfarin in patients with atrial fibrillation based on results of the ENGAGE AF-TIMI 48 trial

artículo científico publicado en 2015

Current and developing strategies for monitoring and reversing direct oral anticoagulants in patients with non-valvular atrial fibrillation.

artículo científico publicado en 2015

Current and new oral antithrombotics in non-valvular atrial fibrillation: a network meta-analysis of 79 808 patients.

artículo científico publicado en 2013

Dabigatran: a review of clinical and pharmacoeconomic evidence.

artículo científico publicado en 2011

Day 1 care in patients with non-ST-segment elevation myocardial infarction.

artículo científico publicado en 2010

Degree of residual stenosis in the culprit coronary artery after thrombolytic administration (Thrombolysis In Myocardial Infarction [TIMI] trials)

artículo científico publicado en 2000

Design and rationale of the EBBINGHAUS trial: A phase 3, double-blind, placebo-controlled, multicenter study to assess the effect of evolocumab on cognitive function in patients with clinically evident cardiovascular disease and receiving statin bac

artículo científico publicado en 2017

Design and rationale of the LAPLACE-TIMI 57 trial: a phase II, double-blind, placebo-controlled study of the efficacy and tolerability of a monoclonal antibody inhibitor of PCSK9 in subjects with hypercholesterolemia on background statin therapy

artículo científico publicado en 2012

Determinants of improvement in epicardial flow and myocardial perfusion for ST elevation myocardial infarction; insights from TIMI 14 and InTIME-II

artículo científico publicado en 2002

Differential expression of cardiac biomarkers by gender in patients with unstable angina/non-ST-elevation myocardial infarction: a TACTICS-TIMI 18 (Treat Angina with Aggrastat and determine Cost of Therapy with an Invasive or Conservative Strategy-T

artículo científico publicado en 2004

Digoxin Use and Subsequent Clinical Outcomes in Patients With Atrial Fibrillation With or Without Heart Failure in the ENGAGE AF-TIMI 48 Trial

artículo científico publicado en 2017

Drug Class, Renal Elimination, and Outcomes of Direct Oral Anticoagulants in Asian Patients: A Meta-Analysis.

artículo científico publicado en 2017

Drug Interaction Between Clopidogrel and Ranitidine or Omeprazole in Stable Coronary Artery Disease: A Double-Blind, Double Dummy, Randomized Study

artículo científico publicado en 2016

ED to catheterization laboratory: a roundtable integrating trials with practice ⬇️

artículo científico publicado el 23 de octubre de 2010

EMBRACE STEMI study: a Phase 2a trial to evaluate the safety, tolerability, and efficacy of intravenous MTP-131 on reperfusion injury in patients undergoing primary percutaneous coronary intervention

artículo científico publicado en 2015

Early and long-term clinical outcomes associated with reinfarction following fibrinolytic administration in the Thrombolysis in Myocardial Infarction trials

artículo científico publicado en 2003

Early coronary intervention following pharmacologic therapy for acute myocardial infarction (the combined TIMI 10B-TIMI 14 experience)

artículo científico publicado en 2001

Early noninvasive detection of failed epicardial reperfusion after fibrinolytic therapy

artículo científico publicado en 2001

Early versus delayed, provisional eptifibatide in acute coronary syndromes

artículo científico publicado en 2009

Edoxaban Versus Warfarin in Atrial Fibrillation Patients at Risk of Falling: ENGAGE AF-TIMI 48 Analysis

artículo científico publicado en 2016

Edoxaban Versus Warfarin in Latin American Patients With Atrial Fibrillation: The ENGAGE AF-TIMI 48 Trial

artículo científico publicado en 2018

Edoxaban or standard therapy with warfarin for stroke prevention in patients with atrial fibrillation?

artículo científico publicado en 2014

Edoxaban vs warfarin in patients with nonvalvular atrial fibrillation in the US Food and Drug Administration approval population: An analysis from the Effective Anticoagulation with Factor Xa Next Generation in Atrial Fibrillation-Thrombolysis in My

artículo científico publicado en 2015

Edoxaban vs. Warfarin in East Asian Patients With Atrial Fibrillation　- An ENGAGE AF-TIMI 48 Subanalysis

artículo científico publicado en 2016

Edoxaban vs. warfarin in vitamin K antagonist experienced and naive patients with atrial fibrillation†

artículo científico publicado en 2015

Edoxaban: Review of pharmacology and key phase I to III clinical trials.

artículo científico publicado en 2014

Edoxaban: pharmacological principles, preclinical and early-phase clinical testing.

artículo científico

Effect of Simvastatin-Ezetimibe Compared With Simvastatin Monotherapy After Acute Coronary Syndrome Among Patients 75 Years or Older: A Secondary Analysis of a Randomized Clinical Trial

scientific article published on 17 July 2019

Effect of rescue or adjunctive percutaneous coronary intervention of the culprit artery after fibrinolytic administration on epicardial flow in nonculprit arteries

artículo científico publicado en 2004

Effectiveness and safety of percutaneous coronary intervention after fibrinolytic therapy for ST-segment elevation acute myocardial infarction.

artículo científico publicado en 2011

Effects of Regional Differences in Asia on Efficacy and Safety of Edoxaban Compared With Warfarin--Insights From the ENGAGE AF-TIMI 48 Trial.

artículo científico publicado en 2015

Effects of tirofiban plus heparin versus heparin alone on troponin I levels in patients with acute coronary syndromes

scientific article published on 01 October 2000

Efficacy and Safety of Adding Ezetimibe to Statin Therapy Among Women and Men: Insight From IMPROVE-IT (Improved Reduction of Outcomes: Vytorin Efficacy International Trial).

artículo científico publicado en 2017

Efficacy and Safety of Edoxaban in Elderly Patients With Atrial Fibrillation in the ENGAGE AF-TIMI 48 Trial

artículo científico publicado en 2016

Efficacy and Safety of Edoxaban in Patients With Active Malignancy and Atrial Fibrillation: Analysis of the ENGAGE AF - TIMI 48 Trial

Efficacy and Safety of Further Lowering of Low-Density Lipoprotein Cholesterol in Patients Starting With Very Low Levels: A Meta-analysis

artículo científico publicado en 2018

Efficacy and Safety of Non-Vitamin K Antagonist Oral Anticoagulants After Cardioversion for Nonvalvular Atrial Fibrillation.

artículo científico publicado en 2016

Efficacy and Safety of Novel Oral Anticoagulants in Patients With Atrial Fibrillation and Heart Failure: A Meta-Analysis.

artículo científico publicado en 2016

Efficacy and safety of edoxaban compared with warfarin in patients with atrial fibrillation and heart failure: insights from ENGAGE AF-TIMI 48.

artículo científico publicado en 2016

Efficacy and safety of evolocumab (AMG 145), a fully human monoclonal antibody to PCSK9, in hyperlipidaemic patients on various background lipid therapies: pooled analysis of 1359 patients in four phase 2 trials

artículo científico publicado en 2014

Efficacy and safety of evolocumab in reducing lipids and cardiovascular events.

artículo científico publicado en 2015

Efficacy and safety of longer-term administration of evolocumab (AMG 145) in patients with hypercholesterolemia: 52-week results from the Open-Label Study of Long-Term Evaluation Against LDL-C (OSLER) randomized trial

artículo científico publicado en 2013

Elevated serum creatinine is associated with 1-year mortality after acute myocardial infarction.

artículo científico publicado en 2002

Emerging antithrombotic drugs for acute coronary syndrome.

artículo científico publicado en 2013

Evaluating cardiovascular event reduction with ezetimibe as an adjunct to simvastatin in 18,144 patients after acute coronary syndromes: final baseline characteristics of the IMPROVE-IT study population

artículo científico publicado en 2014

Evaluation of the novel factor Xa inhibitor edoxaban compared with warfarin in patients with atrial fibrillation: design and rationale for the Effective aNticoaGulation with factor xA next GEneration in Atrial Fibrillation-Thrombolysis In Myocardial

artículo científico publicado en 2010

Evaluation of the time saved by prehospital initiation of reteplase for ST-elevation myocardial infarction: results of The Early Retavase-Thrombolysis in Myocardial Infarction (ER-TIMI) 19 trial

artículo científico publicado en 2002

Evolocumab and Clinical Outcomes in Patients with Cardiovascular Disease

artículo científico publicado en 2017

ExTRACT-TIMI 25 in perspective: key lessons regarding enoxaparin as an adjunct to fibrinolytic therapy.

artículo científico publicado en 2008

Extent of ST-segment resolution after fibrinolysis adds improved risk stratification to clinical risk score for ST-segment elevation myocardial infarction

artículo científico publicado en 2010

Extracranial arterial and venous thromboembolism in patients with atrial fibrillation: A meta-analysis of randomized controlled trials

artículo científico publicado en 2017

Ezetimibe Added to Statin Therapy after Acute Coronary Syndromes

artículo científico publicado en 2015

Fasting glucose, NT-proBNP, treatment with eptifibatide, and outcomes in non-ST-segment elevation acute coronary syndromes: An analysis from EARLY ACS.

artículo científico

First report of an intravenous and oral glycoprotein IIb/IIIa inhibitor (RPR 109891) in patients with recent acute coronary syndromes: results of the TIMI 15A and 15B trials.

artículo científico publicado en 2000

Frequency, clinical and angiographic characteristics, and outcomes of high-risk non-ST-segment elevation acute coronary syndromes patients with left circumflex culprit lesions

artículo científico publicado en 2015

Genetics and the clinical response to warfarin and edoxaban: findings from the randomised, double-blind ENGAGE AF-TIMI 48 trial

artículo científico publicado en 2015

Genotype-guided dosing of warfarin

artículo científico publicado en 2014

Glycoprotein IIb-IIIa inhibitors in the emergency department for patients with non-ST-elevation acute coronary syndromes: principles and practices.

artículo científico publicado en 2008

Heart-type fatty acid binding protein as a marker of reperfusion after thrombolytic therapy

artículo científico publicado en 2000

High-degree atrioventricular block, asystole, and electro-mechanical dissociation complicating non-ST-segment elevation myocardial infarction

artículo científico publicado en 2015

Highlights from the fifth international symposium of thrombosis and anticoagulation (ISTA V), October 18-19, 2012, Belo Horizonte, Minas Gerais, Brazil

artículo científico publicado en 2013

Icosapent Ethyl Reduces Ischemic Events in Patients With a History of Previous Coronary Artery Bypass Grafting: REDUCE-IT CABG

artículo científico publicado en 2021

Identification of patients at high risk for death and cardiac ischemic events after hospital discharge

artículo científico publicado en 2002

Impact of Ezetimibe on the Rate of Cardiovascular-Related Hospitalizations and Associated Costs Among Patients With a Recent Acute Coronary Syndrome: Results From the IMPROVE-IT Trial (Improved Reduction of Outcomes: Vytorin Efficacy International T

artículo científico

Impact of Renal Function on Outcomes With Edoxaban in the ENGAGE AF-TIMI 48 Trial

artículo científico

Impact of time of presentation on process performance and outcomes in ST-segment-elevation myocardial infarction: a report from the American Heart Association: Mission Lifeline program

artículo científico publicado en 2014

Improving antithrombotic treatment in patients after myocardial infarction

artículo científico publicado en 2003

In patients with acute myocardial infarction, the impact of hyperglycemia as a risk factor for mortality is not homogeneous across age-groups.

artículo científico publicado en 2011

Incidence, treatment, and outcomes of atrial fibrillation complicating non-ST-segment elevation acute coronary syndromes

artículo científico publicado en 2013

Individual Patient Data from the Pivotal Randomized Controlled Trials of Non-Vitamin K Antagonist Oral Anticoagulants in Patients with Atrial Fibrillation (COMBINE AF): Design and Rationale: From the COMBINE AF (A COllaboration between Multiple inst

scientific article published on 06 December 2020

Inflammatory and Cholesterol Risk in the FOURIER Trial (Further Cardiovascular Outcomes Research With PCSK9 Inhibition in Patients With Elevated Risk).

artículo científico publicado en 2018

Influence of proven oral therapies in the very old with acute coronary syndromes: A 15 year experience

artículo científico publicado en 2015

Left atrial structure and function in atrial fibrillation: ENGAGE AF-TIMI 48.

artículo científico publicado en 2013

Left bundle branch block in non-ST-segment elevation acute coronary syndromes. Incidence, angiographic characteristics, and clinical outcomes.

artículo científico publicado en 2013

Linking Endogenous Factor Xa Activity, a Biologically Relevant Pharmacodynamic Marker, to Edoxaban Plasma Concentrations and Clinical Outcomes in the ENGAGE AF-TIMI 48 Trial

artículo científico publicado en 2018

Long-term Low-Density Lipoprotein Cholesterol-Lowering Efficacy, Persistence, and Safety of Evolocumab in Treatment of Hypercholesterolemia: Results Up to 4 Years From the Open-Label OSLER-1 Extension Study.

artículo científico

Long-term Safety and Efficacy of Achieving Very Low Levels of Low-Density Lipoprotein Cholesterol : A Prespecified Analysis of the IMPROVE-IT Trial

artículo científico

Low-Density Lipoprotein Cholesterol Lowering With Evolocumab and Outcomes in Patients With Peripheral Artery Disease: Insights From the FOURIER Trial (Further Cardiovascular Outcomes Research With PCSK9 Inhibition in Subjects With Elevated Risk).

artículo científico publicado en 2017

Low-Density Lipoprotein Cholesterol Treatment in the Proprotein Convertase Subtilisin/Kexin Type 9 Inhibitor Era: Getting Back on Target

artículo científico publicado en 2017

Low-density lipoprotein lowering in 2013 by nonstatin agents: the discovery and development of promising novel targeted therapies.

artículo científico

Low-molecular-weight heparins for the treatment of acute coronary syndromes.

artículo científico publicado en 2003

Major Bleeding in Patients With Diabetes and Atrial Fibrillation Treated With New Oral Anticoagulants-Reply

artículo científico publicado en 2017

Management of LDL-cholesterol after an acute coronary syndrome: Key comparisons of the American and European clinical guidelines to the attention of the healthcare providers

artículo científico publicado en 2020

Management of ST-elevation myocardial infarction: an update on pharmacoinvasive recanalization.

artículo científico publicado en 2008

Management of ST-segment elevation myocardial infarction: Comparison of the updated guidelines from North America and Europe.

artículo científico publicado en 2009

Medication Discontinuation in the IMPROVE-IT Trial

scientific article published on 01 January 2019

Modes and timing of death in 66 252 patients with non-ST-segment elevation acute coronary syndromes enrolled in 14 TIMI trials

scientific article published on 01 November 2018

Mortality in Patients with Atrial Fibrillation Randomized to Edoxaban or Warfarin: Insights from the ENGAGE AF-TIMI 48 Trial

artículo científico publicado en 2016

Neural network assessment of perioperative cardiac risk in vascular surgery patients.

artículo científico publicado en 1998

Neural networks, logistic regression, and calibration: a reply.

artículo científico publicado en 1998

New oral anticoagulants in patients with atrial fibrillation - Authors'reply

artículo científico publicado en 2014

Niacin at 56 years of age--time for an early retirement?

artículo científico publicado en 2011

Non-Vitamin K Antagonist Oral Anticoagulants for Mechanical Heart Valves

scientific article published on 01 September 2018

Non-Vitamin K Antagonist Oral Anticoagulants in Atrial Fibrillation

artículo científico publicado en 2016

Non-Vitamin K Antagonist Oral Anticoagulants in Patients With Atrial Fibrillation and Valvular Heart Disease.

artículo científico publicado en 2017

Nonvitamin K Anticoagulant Agents in Patients With Advanced Chronic Kidney Disease or on Dialysis With AF.

artículo científico publicado en 2016

North American Thrombosis Forum, AF Action Initiative Consensus Document

artículo científico publicado en 2016

Novel biomarkers in cardiovascular disease: update 2010.

artículo científico publicado en 2010

Novel oral anticoagulants in atrial fibrillation: a meta-analysis of large, randomized, controlled trials vs warfarin

artículo científico

Obesity, Diabetes, and Acute Coronary Syndrome: Differences Between Asians and Whites

artículo científico publicado en 2017

On-treatment analysis of the Improved Reduction of Outcomes: Vytorin Efficacy International Trial (IMPROVE-IT).

artículo científico publicado en 2016

Once- or twice-daily non-vitamin K antagonist oral anticoagulants in Asian patients with atrial fibrillation: A meta-analysis of randomized controlled trials.

artículo científico publicado en 2017

One-year outcomes after a strategy using enoxaparin vs. unfractionated heparin in patients undergoing fibrinolysis for ST-segment elevation myocardial infarction: 1-year results of the ExTRACT-TIMI 25 trial

artículo científico publicado en 2010

Oral Anticoagulation in Patients With Liver Disease.

artículo científico publicado en 2018

Outcomes With Edoxaban Versus Warfarin in Patients With Previous Cerebrovascular Events: Findings From ENGAGE AF-TIMI 48 (Effective Anticoagulation With Factor Xa Next Generation in Atrial Fibrillation-Thrombolysis in Myocardial Infarction 48).

artículo científico

Outcomes among non-ST-segment elevation acute coronary syndromes patients with no angiographically obstructive coronary artery disease: observations from 37,101 patients

scientific article published on 09 May 2013

Overcoming global challenges in stroke prophylaxis in atrial fibrillation: The role of non-vitamin K antagonist oral anticoagulants

artículo científico publicado en 2016

Overview of Oral Antithrombotic Treatment in Elderly Patients with Atrial Fibrillation

article

PCSK9 inhibition-mediated reduction in Lp(a) with evolocumab: an analysis of 10 clinical trials and the LDL receptor's role

artículo científico publicado en 2016

PCSK9 inhibitors for prevention of atherosclerotic cardiovascular disease

artículo científico publicado en 2018

PCSK9 inhibitors for treating dyslipidemia in patients at different cardiovascular risk: a systematic review and a meta-analysis.

artículo científico publicado en 2017

Patterns and predictors of lipid-lowering therapy in patients with atherosclerotic cardiovascular disease and/or diabetes mellitus in 2014: Insights from a large US managed-care population

artículo científico publicado en 2016

Performance of the thrombolysis in myocardial infarction risk index in the National Registry of Myocardial Infarction-3 and -4: a simple index that predicts mortality in ST-segment elevation myocardial infarction

artículo científico publicado en 2004

Peri-operative Adverse Outcomes in Patients with Atrial Fibrillation Taking Warfarin or Edoxaban: Analysis of the ENGAGE AF-TIMI 48 Trial

scientific article published on 03 May 2018

Perioperative management of target-specific oral anticoagulants

artículo científico publicado en 2014

Perspectives on the 2009 focused updates on the management of ST-segment elevation myocardial infarction and percutaneous intervention.

scientific article published on September 2010

Polyvascular disease, type 2 diabetes, and long-term vascular risk: a secondary analysis of the IMPROVE-IT trial

artículo científico publicado en 2018

Poor outcomes after fibrinolytic therapy for ST-segment elevation myocardial infarction: impact of age (a meta-analysis of a decade of trials)

artículo científico publicado en 2006

Predicting Benefit From Evolocumab Therapy in Patients With Atherosclerotic Disease Using a Genetic Risk Score: Results From the FOURIER Trial

artículo científico publicado en 2019

Predictors of bleeding and time dependence of association of bleeding with mortality: insights from the Trial to Assess Improvement in Therapeutic Outcomes by Optimizing Platelet Inhibition With Prasugrel--Thrombolysis in Myocardial Infarction 38 (T

artículo científico

Predictors of long-term mortality after hospitalization for primary unstable angina pectoris and non-ST-elevation myocardial infarction.

artículo científico publicado en 2003

Prevalence and clinical outcomes of undiagnosed diabetes mellitus and prediabetes among patients with high-risk non-ST-segment elevation acute coronary syndrome

artículo científico publicado en 2013

Prevention of Stroke with the Addition of Ezetimibe to Statin Therapy in Patients With Acute Coronary Syndrome in IMPROVE-IT (Improved Reduction of Outcomes: Vytorin Efficacy International Trial).

artículo científico publicado en 2017

Prior aspirin use and outcomes in acute coronary syndromes

artículo científico publicado en 2010

Prognostic and Practical Validation of Current Definitions of Myocardial Infarction Associated With Percutaneous Coronary Intervention.

artículo científico publicado en 2018

Prognostic implications of low level cardiac troponin elevation using high-sensitivity cardiac troponin T

artículo científico publicado en 2015

Prognostic performance of a high-sensitivity cardiac troponin I assay in patients with non-ST-elevation acute coronary syndrome

artículo científico publicado en 2013

Prognostic value of SPECT myocardial perfusion imaging in patients with elevated cardiac troponin I levels and atypical clinical presentation.

artículo científico publicado en 2007

Radial versus femoral access, bleeding and ischemic events in patients with non-ST-segment elevation acute coronary syndrome managed with an invasive strategy

artículo científico publicado en 2013

Rationale and design of IMPROVE-IT (IMProved Reduction of Outcomes: Vytorin Efficacy International Trial): comparison of ezetimbe/simvastatin versus simvastatin monotherapy on cardiovascular outcomes in patients with acute coronary syndromes

artículo científico publicado en 2008

Rationale and design of the EMBRACE STEMI study: a phase 2a, randomized, double-blind, placebo-controlled trial to evaluate the safety, tolerability and efficacy of intravenous Bendavia on reperfusion injury in patients treated with standard therapy

artículo científico publicado en 2013

Rationale and design of the Further cardiovascular OUtcomes Research with PCSK9 Inhibition in subjects with Elevated Risk trial.

artículo científico publicado en 2015

Recombinant nematode anticoagulant protein c2 in patients with non-ST-segment elevation acute coronary syndrome: the ANTHEM-TIMI-32 trial

artículo científico publicado en 2007

Reduction in Total Cardiovascular Events With Ezetimibe/Simvastatin Post-Acute Coronary Syndrome: The IMPROVE-IT Trial

artículo científico publicado en 2016

Reduction in lipoprotein(a) with PCSK9 monoclonal antibody evolocumab (AMG 145): a pooled analysis of more than 1,300 patients in 4 phase II trials.

artículo científico publicado en 2014

Reexamination of the Thrombin Hypothesis: What We Have Learned from TIMI 9B and GUSTO IIb

artículo científico publicado en 1997

Regional patterns of use of a medical management strategy for patients with non-ST-segment elevation acute coronary syndromes: insights from the EARLY ACS Trial

artículo científico publicado en 2012

Relation between time of symptom onset of ST-segment elevation myocardial infarction and patient baseline characteristics: from the National Cardiovascular Data Registry

artículo científico publicado en 2013

Relation of Left Ventricular Mass and Infarct Size in Anterior Wall ST-Segment Elevation Acute Myocardial Infarction (from the EMBRACE STEMI Clinical Trial).

artículo científico publicado en 2016

Relation of impaired Thrombolysis In Myocardial Infarction myocardial perfusion grades to residual thrombus following the restoration of epicardial patency in ST-elevation myocardial infarction

artículo científico publicado en 2005

Relations between bleeding and outcomes in patients with ST-elevation myocardial infarction in the ExTRACT-TIMI 25 trial

artículo científico publicado en 2010

Relationships among race, bleeding, and mortality in coronary reperfusion

artículo científico publicado en 2012

Reply: Adding Ezetimibe to Simvastatin for the Secondary Prevention of Cardiovascular Disease: Is it Useful?

artículo científico publicado en 2016

Reply: Ezetimibe, Risk Stratification, and Secondary Prevention

artículo científico publicado en 2017

Reply: Personalize and Optimize Lipid-Lowering Therapies

artículo científico publicado en 2016

Response by Bohula et al to Letters Regarding Article, "Prevention of Stroke With the Addition of Ezetimibe to Statin Therapy in Patients With Acute Coronary Syndrome in IMPROVE-IT (Improved Reduction of Outcomes: Vytorin Efficacy International Tria

artículo científico publicado en 2018

Response to Letter Regarding Article, "Achievement of Dual Low-Density Lipoprotein Cholesterol and High-Sensitivity C-Reactive Protein Targets More Frequent With the Addition of Ezetimibe to Simvastatin and Associated With Better Outcomes in IMPROVE

artículo científico publicado en 2016

Response to letter regarding article, “sustained ventricular tachycardia and ventricular fibrillation complicating non–ST-segment elevation acute coronary syndromes”

artículo científico publicado en 2013

Risk of thrombocytopenia with glycoprotein IIb/IIIa inhibitors across drugs and patient populations: a meta-analysis of 29 large placebo-controlled randomized trials

artículo científico publicado en 2015

Routine early eptifibatide versus delayed provisional use at percutaneous coronary intervention in high-risk non-ST-segment elevation acute coronary syndromes patients: an analysis from the Early Glycoprotein IIb/IIIa Inhibition in Non-ST-Segment El

artículo científico publicado en 2013

ST-segment resolution and infarct-related artery patency and flow after thrombolytic therapy. Thrombolysis in Myocardial Infarction (TIMI) 14 investigators

artículo científico publicado en 2000

Safety and efficacy of adjusted-dose eptifibatide in patients with acute coronary syndromes and reduced renal function

artículo científico publicado en 2011

Safety and efficacy of prasugrel compared with clopidogrel in different regions of the world

artículo científico publicado en 2010

Selecting an oral anticoagulant for patients with nonvalvular atrial fibrillation

artículo científico publicado en 2015

Selecting the best reperfusion strategy in ST-elevation myocardial infarction: it's all a matter of time

artículo científico publicado en 2003

Sequential risk stratification using TIMI risk score and TIMI flow grade among patients treated with fibrinolytic therapy for ST-segment elevation acute myocardial infarction

artículo científico publicado en 2004

Severity of heart failure, treatments, and outcomes after fibrinolysis in patients with ST-elevation myocardial infarction

artículo científico publicado en 2004

Sex-Stratified Trends in Enrollment, Patient Characteristics, Treatment, and Outcomes Among Non-ST-Segment Elevation Acute Coronary Syndrome Patients: Insights From Clinical Trials Over 17 Years

artículo científico publicado en 2015

Standard dose versus low dose non-vitamin K antagonist oral anticoagulants in Asian patients with atrial fibrillation: A meta-analysis of contemporary randomized controlled trials.

artículo científico publicado en 2016

Stroke and Mortality Risk in Patients With Various Patterns of Atrial Fibrillation: Results From the ENGAGE AF-TIMI 48 Trial (Effective Anticoagulation With Factor Xa Next Generation in Atrial Fibrillation-Thrombolysis in Myocardial Infarction 48).

artículo científico

Sudden Cardiac Death in Patients With Atrial Fibrillation: Insights From the ENGAGE AF-TIMI 48 Trial

scientific article published on 08 July 2016

Sustained ventricular tachycardia and ventricular fibrillation complicating non-ST-segment-elevation acute coronary syndromes

artículo científico

Systemic, noncerebral, arterial embolism in 21,105 patients with atrial fibrillation randomized to edoxaban or warfarin: results from the Effective Anticoagulation With Factor Xa Next Generation in Atrial Fibrillation-Thrombolysis in Myocardial Infa

artículo científico publicado en 2015

TIMI Risk Score for ST-Elevation Myocardial Infarction: A Convenient, Bedside, Clinical Score for Risk Assessment at Presentation : An Intravenous nPA for Treatment of Infarcting Myocardium Early II Trial Substudy

artículo científico publicado en 2000

TNK-tissue plasminogen activator compared with front-loaded alteplase in acute myocardial infarction: results of the TIMI 10B trial. Thrombolysis in Myocardial Infarction (TIMI) 10B Investigators

scientific article published on 01 December 1998

Target-specific oral anticoagulants: practice issues for the clinician.

artículo científico

The Early Glycoprotein IIb/IIIa Inhibition in Non–ST-Segment Elevation Acute Coronary Syndrome (EARLY ACS) trial: A randomized placebo-controlled trial evaluating the clinical benefits of early front-loaded eptifibatide in the treatment of patients

article

The Effect of PCSK9 Inhibition on the Risk of Venous Thromboembolism

artículo científico publicado en 2020

The P-glycoprotein transport system and cardiovascular drugs.

artículo científico publicado en 2013

The Prognostic Significance of Cardiac Structure and Function in Atrial Fibrillation: The ENGAGE AF-TIMI 48 Echocardiographic Substudy

artículo científico publicado en 2016

The Risk Score Profile: a novel approach to characterising the risk of populations enrolled in clinical studies

artículo científico publicado en 2004

The Use of Oral Beta-Blockers and Clinical Outcomes in Patients with Non-ST-Segment Elevation Acute Coronary Syndromes: a Long-Term Follow-Up Study

scientific article published on 01 October 2018

The benefit of adding ezetimibe to statin therapy in patients with prior coronary artery bypass graft surgery and acute coronary syndrome in the IMPROVE-IT trial.

artículo científico publicado en 2016

The independent and combined risk of diabetes and non-endstage renal impairment in non-ST-segment elevation acute coronary syndromes

scientific article published on 09 January 2008

The nonalcoholic fatty liver disease (NAFLD) fibrosis score, cardiovascular risk stratification and a strategy for secondary prevention with ezetimibe

artículo científico publicado en 2018

The prognostic value of serum creatinine on admission in fibrinolytic-eligible patients with acute myocardial infarction.

artículo científico publicado en 2003

The relationship between meteorological conditions and index acute coronary events in a global clinical trial

artículo científico publicado en 2013

The role of clopidogrel in early and sustained arterial patency after fibrinolysis for ST-segment elevation myocardial infarction: the ECG CLARITY-TIMI 28 Study

artículo científico publicado en 2006

The role of rivaroxaban in atrial fibrillation and acute coronary syndromes

artículo científico publicado en 2014

The year in non-ST-segment elevation acute coronary syndrome

artículo científico publicado en 2007

The year in non-ST-segment elevation acute coronary syndrome

artículo científico publicado en 2008

The year in non-ST-segment elevation acute coronary syndrome

scientific article published on December 2010

The year in non-ST-segment elevation acute coronary syndromes

artículo científico publicado en 2005

The year in non-ST-segment elevation acute coronary syndromes

artículo científico publicado en 2006

Thiazolidinedione drugs and cardiovascular risks: a science advisory from the American Heart Association and American College Of Cardiology Foundation

artículo científico publicado en 2010

Thiazolidinedione drugs and cardiovascular risks: a science advisory from the American Heart Association and American College of Cardiology Foundation.

scientific article published on 23 February 2010

Thrombolysis in Myocardial Infarction (TIMI) Risk Index predicts long-term mortality and heart failure in patients with ST-elevation myocardial infarction in the TIMI 2 clinical trial

artículo científico publicado en 2009

Ticagrelor for the prevention of ischemic events in patients with prior myocardial infarction and peripheral artery disease.

artículo científico publicado en 2018

Transition of patients from blinded study drug to open-label anticoagulation: the ENGAGE AF-TIMI 48 trial

artículo científico publicado en 2014

Treatment strategies in non-ST-elevation acute coronary syndromes in patients undergoing percutaneous coronary intervention: an evidence-based review of clinical trial results and treatment guidelines: report on a roundtable discussion.

artículo científico publicado en 2008

Trends in Enrollment, Clinical Characteristics, Treatment, and Outcomes According to Age in Non-ST-Segment-Elevation Acute Coronary Syndromes Clinical Trials

artículo científico publicado en 2016

Trends in clinical trials of non-ST-segment elevation acute coronary syndromes over 15 years

artículo científico publicado en 2012

U-shaped relationship of blood glucose with adverse outcomes among patients with ST-segment elevation myocardial infarction

artículo científico publicado en 2005

Updates on Acute Coronary Syndrome: A Review

artículo científico publicado en 2016

Upstream Clopidogrel Use and the Efficacy and Safety of Early Eptifibatide Treatment in Patients With Acute Coronary Syndrome

article

Upstream use of small-molecule glycoprotein iib/iiia inhibitors in patients with non-ST-segment elevation acute coronary syndromes: a systematic overview of randomized clinical trials

artículo científico publicado en 2011

Usefulness of prodromal unstable angina pectoris in predicting better survival and smaller infarct size in acute myocardial infarction (The InTIME-II Prodromal Symptoms Substudy).

artículo científico publicado en 2003

Usefulness of the TIMI Risk Index in Predicting Short- and Long-Term Mortality in Patients With Acute Coronary Syndromes

article

Valvular Heart Disease Patients on Edoxaban or Warfarin in the ENGAGE AF-TIMI 48 Trial.

artículo científico publicado en 2017

Variation in PCSK9 and HMGCR and Risk of Cardiovascular Disease and Diabetes

artículo científico publicado en 2016

Very early risk stratification after thrombolytic therapy with a bedside myoglobin assay and the 12-lead electrocardiogram

scientific article published on 01 September 2000

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