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Lista de obras de Lisa M Butler

A Novel Class of Hsp90 C-Terminal Modulators Have Pre-Clinical Efficacy in Prostate Tumor Cells Without Induction of a Heat Shock Response

artículo científico publicado en 2016

A ZEB1-miR-375-YAP1 pathway regulates epithelial plasticity in prostate cancer.

artículo científico publicado en 2016

A feedback loop between the androgen receptor and 6-phosphogluoconate dehydrogenase (6PGD) drives prostate cancer growth

artículo científico publicado en 2021

A gene signature identified using a mouse model of androgen receptor-dependent prostate cancer predicts biochemical relapse in human disease

artículo científico publicado en 2012

A patient-derived explant (PDE) model of hormone-dependent cancer

artículo científico publicado en 2018

Altered endosome biogenesis in prostate cancer has biomarker potential

artículo científico publicado en 2014

An Analysis of a Multiple Biomarker Panel to Better Predict Prostate Cancer Metastasis After Radical Prostatectomy

artículo científico publicado en 2018

An androgen receptor mutation in the MDA-MB-453 cell line model of molecular apocrine breast cancer compromises receptor activity

artículo científico publicado en 2012

Androgen control of lipid metabolism in prostate cancer: novel insights and future applications

artículo científico publicado en 2016

Antiproliferative actions of the synthetic androgen, mibolerone, in breast cancer cells are mediated by both androgen and progesterone receptors.

artículo científico publicado en 2008

Assessment of Periprostatic and Subcutaneous Adipose Tissue Lipolysis and Adipocyte Size from Men with Localized Prostate Cancer

artículo científico publicado en 2020

Bringing androgens up a NOTCH in breast cancer

artículo científico publicado en 2014

Characterization of the prostate cancer susceptibility gene KLF6 in human and mouse prostate cancers.

artículo científico publicado en 2012

Circulating microRNAs: macro-utility as markers of prostate cancer?

artículo científico publicado en 2012

Co-targeting AR and HSP90 suppresses prostate cancer cell growth and prevents resistance mechanisms

artículo científico publicado en 2015

Constitutively-active androgen receptor variants function independently of the HSP90 chaperone but do not confer resistance to HSP90 inhibitors.

artículo científico publicado en 2013

Corepressor effect on androgen receptor activity varies with the length of the CAG encoded polyglutamine repeat and is dependent on receptor/corepressor ratio in prostate cancer cells.

artículo científico publicado en 2011

Differential effects of exogenous androgen and an androgen receptor antagonist in the peri- and postpubertal murine mammary gland.

artículo científico publicado en 2011

Drug-Induced Epigenomic Plasticity Reprograms Circadian Rhythm Regulation to Drive Prostate Cancer toward Androgen Independence

artículo científico publicado en 2022

Dual roles of PARP-1 promote cancer growth and progression

artículo científico publicado en 2012

Dysregulated fibronectin trafficking by Hsp90 inhibition restricts prostate cancer cell invasion

artículo científico publicado en 2018

Effect of FAK inhibitor VS-6063 (defactinib) on docetaxel efficacy in prostate cancer.

artículo científico publicado en 2018

Endosomal gene expression: a new indicator for prostate cancer patient prognosis?

artículo científico publicado en 2015

Erratum to: IκBα mediates prostate cancer cell death induced by combinatorial targeting of the androgen receptor

artículo científico publicado en 2016

Evaluation of Small Molecule Drug Uptake in Patient-Derived Prostate Cancer Explants by Mass Spectrometry

scientific article published on 18 October 2019

Evidence for efficacy of new Hsp90 inhibitors revealed by ex vivo culture of human prostate tumors.

artículo científico publicado en 2012

Ex vivo culture of human prostate tissue and drug development

artículo científico

Extracellular Fatty Acids Are the Major Contributor to Lipid Synthesis in Prostate Cancer

artículo científico publicado en 2019

Fatty acid oxidation is an adaptive survival pathway induced in prostate tumors by heat shock protein 90 inhibition

artículo científico publicado en 2020

Finding the place of histone deacetylase inhibitors in prostate cancer therapy.

artículo científico publicado en 2009

GSTP1 DNA methylation and expression status is indicative of 5-aza-2'-deoxycytidine efficacy in human prostate cancer cells

artículo científico publicado en 2011

Global levels of specific histone modifications and an epigenetic gene signature predict prostate cancer progression and development

artículo científico publicado en 2010

High expression of TROP2 characterizes different cell subpopulations in androgen-sensitive and androgen-independent prostate cancer cells.

artículo científico publicado en 2016

Human DECR1 is an androgen-repressed survival factor that regulates PUFA oxidation to protect prostate tumor cells from ferroptosis

scientific article published on 20 July 2020

Human ex vivo prostate tissue model system identifies ING3 as an oncoprotein

artículo científico publicado en 2018

Human seminal fluid as a source of prostate cancer-specific microRNA biomarkers

article

Identification of novel response and predictive biomarkers to Hsp90 inhibitors through mass spectrometry-based proteomic profiling of patient-derived prostate tumor explants.

artículo científico publicado en 2018

Identification of prostate cancer-associated microRNAs in circulation using a mouse model of disease.

artículo científico publicado en 2013

Inhibition of de novo lipogenesis targets androgen receptor signaling in castration-resistant prostate cancer

article published in the Proceedings of the National Academy of Sciences of the United States of America

Knockdown of the cochaperone SGTA results in the suppression of androgen and PI3K/Akt signaling and inhibition of prostate cancer cell proliferation.

artículo científico publicado en 2013

Maximizing the Therapeutic Potential of HSP90 Inhibitors

artículo científico publicado en 2015

MicroRNA-194 Promotes Prostate Cancer Metastasis by Inhibiting SOCS2.

artículo científico publicado en 2016

Molecular and structural basis of androgen receptor responses to dihydrotestosterone, medroxyprogesterone acetate and Δ(4)-tibolone.

artículo científico publicado en 2013

Molecular pathology and prostate cancer therapeutics: from biology to bedside

artículo científico

Multiple nuclear receptor signaling pathways mediate the actions of synthetic progestins in target cells

artículo científico publicado el 16 de septiembre de 2011

New Opportunities for Targeting the Androgen Receptor in Prostate Cancer.

artículo científico publicado en 2018

Osteoblast derived-neurotrophin‑3 induces cartilage removal proteases and osteoclast-mediated function at injured growth plate in rats

scientific article published on 17 August 2018

Patient-derived Models Reveal Impact of the Tumor Microenvironment on Therapeutic Response

scientific article published on 06 June 2018

Peptidomimetic targeting of critical androgen receptor-coregulator interactions in prostate cancer

artículo científico publicado en 2013

Peri-Prostatic Adipose Tissue: The metabolic microenvironment of prostate cancer.

artículo científico publicado en 2018

Precision nanomedicines for prostate cancer

artículo científico publicado en 2018

Prostate cell lines as models for biomarker discovery: performance of current markers and the search for new biomarkers

artículo científico publicado en 2014

Reciprocal signaling between mTORC1 and MNK2 controls cell growth and oncogenesis

artículo científico publicado en 2020

Ski-interacting protein (SKIP) interacts with androgen receptor in the nucleus and modulates androgen-dependent transcription.

artículo científico publicado en 2013

Subdomain structure of the co-chaperone SGTA and activity of its androgen receptor client

scholarly article by Andrew P Trotta published in June 2012

Targeting cell cycle and hormone receptor pathways in cancer.

artículo científico publicado en 2013

The Combination of Metformin and Valproic Acid Induces Synergistic Apoptosis in the Presence of p53 and Androgen Signaling in Prostate Cancer

artículo científico publicado en 2017

The Magnitude of Androgen Receptor Positivity in Breast Cancer Is Critical for Reliable Prediction of Disease Outcome.

artículo científico publicado en 2018

The dynamic and static modification of the epigenome by hormones: a role in the developmental origin of hormone related cancers.

artículo científico publicado en 2009

The inverse relationship between prostate specific antigen (PSA) and obesity

artículo científico publicado en 2018

Therapeutic response to CDK4/6 inhibition in breast cancer defined by ex vivo analyses of human tumors.

artículo científico publicado en 2012