Lista de obras - Yoonjoo Choi - Dominio Público Uruguay

A Chimeric Antigen Receptor That Binds to a Conserved Site on MICA

artículo científico publicado en 2020

Antibody humanization by structure-based computational protein design.

artículo científico publicado en 2015

B-SIDER: Computational Algorithm for the Design of Complementary β-Sheet Sequences

artículo científico publicado en 2019

Computationally driven antibody engineering enables simultaneous humanization and thermostabilization.

artículo científico publicado en 2016

Computationally driven deletion of broadly distributed T cell epitopes in a biotherapeutic candidate.

artículo científico publicado en 2014

Computationally-driven identification of antibody epitopes.

artículo científico publicado en 2017

Computer-guided binding mode identification and affinity improvement of an LRR protein binder without structure determination

scientific article published on 31 August 2020

Deimmunization of flagellin for repeated administration as a vaccine adjuvant

artículo científico publicado en 2021

Depletion of T cell epitopes in lysostaphin mitigates anti-drug antibody response and enhances antibacterial efficacy in vivo.

artículo científico publicado en 2015

Developing stochastic models for spatial inference: bacterial chemotaxis

artículo científico publicado en 2010

DisruPPI: structure-based computational redesign algorithm for protein binding disruption.

artículo científico publicado en 2018

Effective inhibition of C3a-mediated pro-inflammatory response by a human C3a-specific protein binder

scientific article published on 18 February 2020

EpiSweep: Computationally Driven Reengineering of Therapeutic Proteins to Reduce Immunogenicity While Maintaining Function

artículo científico publicado en 2017

FREAD revisited: Accurate loop structure prediction using a database search algorithm.

artículo científico publicado en 2010

Fragment-based modeling of membrane protein loops: successes, failures, and prospects for the future

artículo científico publicado en 2013

Gene and protein sequence optimization for high-level production of fully active and aglycosylated lysostaphin in Pichia pastoris.

artículo científico publicado en 2014

GradDock: Rapid Simulation and Tailored Ranking Functions for Peptide-MHC Class I Docking.

artículo científico publicado en 2017

How long is a piece of loop?

artículo científico publicado en 2013

Mapping the Pareto optimal design space for a functionally deimmunized biotherapeutic candidate

artículo científico publicado en 2015

Predicting antibody complementarity determining region structures without classification ⬇️

artículo científico publicado el 20 de octubre de 2011

Protein Modeling and Structural Prediction

Protein deimmunization via structure-based design enables efficient epitope deletion at high mutational loads

artículo científico publicado en 2015

Repeat Module-Based Rational Design of a Photoswitchable Protein for Light-Driven Control of Biological Processes

artículo científico publicado en 2018

Structure-based redesign of lysostaphin yields potent antistaphylococcal enzymes that evade immune cell surveillance.

artículo científico publicado en 2015

Structure-guided deimmunization of therapeutic proteins

artículo científico publicado en 2013

Structure‐based redesign of proteins for minimal T‐cell epitope content ⬇️

artículo científico publicado el 8 de enero de 2013

Lista de obras de Yoonjoo Choi

A Chimeric Antigen Receptor That Binds to a Conserved Site on MICA

Antibody humanization by structure-based computational protein design.

B-SIDER: Computational Algorithm for the Design of Complementary β-Sheet Sequences

Computationally driven antibody engineering enables simultaneous humanization and thermostabilization.

Computationally driven deletion of broadly distributed T cell epitopes in a biotherapeutic candidate.

Computationally-driven identification of antibody epitopes.

Computer-guided binding mode identification and affinity improvement of an LRR protein binder without structure determination

Deimmunization of flagellin for repeated administration as a vaccine adjuvant

Depletion of T cell epitopes in lysostaphin mitigates anti-drug antibody response and enhances antibacterial efficacy in vivo.

Developing stochastic models for spatial inference: bacterial chemotaxis

DisruPPI: structure-based computational redesign algorithm for protein binding disruption.

Effective inhibition of C3a-mediated pro-inflammatory response by a human C3a-specific protein binder

EpiSweep: Computationally Driven Reengineering of Therapeutic Proteins to Reduce Immunogenicity While Maintaining Function

FREAD revisited: Accurate loop structure prediction using a database search algorithm.

Fragment-based modeling of membrane protein loops: successes, failures, and prospects for the future

Gene and protein sequence optimization for high-level production of fully active and aglycosylated lysostaphin in Pichia pastoris.

GradDock: Rapid Simulation and Tailored Ranking Functions for Peptide-MHC Class I Docking.

How long is a piece of loop?

Mapping the Pareto optimal design space for a functionally deimmunized biotherapeutic candidate

Predicting antibody complementarity determining region structures without classification ⬇️

Protein Modeling and Structural Prediction

Protein deimmunization via structure-based design enables efficient epitope deletion at high mutational loads

Repeat Module-Based Rational Design of a Photoswitchable Protein for Light-Driven Control of Biological Processes

Structure-based redesign of lysostaphin yields potent antistaphylococcal enzymes that evade immune cell surveillance.

Structure-guided deimmunization of therapeutic proteins

Structure‐based redesign of proteins for minimal T‐cell epitope content ⬇️