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A subgroup of malignant fibrous histiocytomas is associated with genetic changes similar to those of well-differentiated liposarcomas.

artículo científico publicado en 2002

Constitutive activation of RAS/MAPK pathway cooperates with trisomy 21 and is therapeutically exploitable in Down syndrome B-cell leukemia

scientific article published on 27 March 2020

DYRK1A controls the transition from proliferation to quiescence during lymphoid development by destabilizing Cyclin D3

artículo científico publicado en 2015

ETO2-GLIS2 Hijacks Transcriptional Complexes to Drive Cellular Identity and Self-Renewal in Pediatric Acute Megakaryoblastic Leukemia.

artículo científico publicado en 2017

Gain of chromosome 21 in hematological malignancies: lessons from studying leukemia in children with Down syndrome

scientific article published on 20 May 2020

Genetic characterization of TET1, TET2, and TET3 alterations in myeloid malignancies

artículo científico publicado en 2009

Ikaros inhibits megakaryopoiesis through functional interaction with GATA-1 and NOTCH signaling

artículo científico publicado en 2013

Increased dosage of the chromosome 21 ortholog Dyrk1a promotes megakaryoblastic leukemia in a murine model of Down syndrome.

artículo científico publicado en 2012

Insights into the manifestations, outcomes, and mechanisms of leukemogenesis in Down syndrome

artículo científico publicado en 2009

Molecular pathways driven by ETO2-GLIS2 in aggressive pediatric leukemia.

artículo científico publicado en 2017

Mutational analysis of candidate tumor-associated genes in acute megakaryoblastic leukemia

artículo científico publicado en 2009

Notch: of mice and men? ⬇️

artículo científico publicado el 16 de diciembre de 2010

Nucleophosmin status may influence the therapeutic decision in de novo acute myeloid leukemia with normal karyotype

artículo científico publicado en 2006

Ontogenic Changes in Hematopoietic Hierarchy Determine Pediatric Specificity and Disease Phenotype in Fusion Oncogene-Driven Myeloid Leukemia

scientific article published on 29 October 2019

Pediatric Acute Megakaryoblastic Leukemia: Multitasking Fusion Proteins and Oncogenic Cooperations.

artículo científico publicado en 2017

Targeting megakaryocytic-induced fibrosis in myeloproliferative neoplasms by AURKA inhibition.

artículo científico publicado en 2015

The mitochondrial respiratory chain is essential for haematopoietic stem cell function.

artículo científico publicado en 2017

Triplication of a 21q22 region contributes to B cell transformation through HMGN1 overexpression and loss of histone H3 Lys27 trimethylation

artículo científico publicado en 2014

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