Lista de obras - Dariusz Matosiuk - Dominio Público Uruguay

1-(3-Chloro-phen-yl)-3-(1-p-tolyl-imidazolidin-2-yl-idene)urea

artículo científico publicado en 2008

6-(2-Chloro-benz-yl)-1-(4-chloro-phen-yl)-7-hy-droxy-2,3-dihydro-1H-imidazo[1,2-a]pyrimidin-5-one.

artículo científico publicado en 2010

Activation and Allosteric Modulation of Human μ Opioid Receptor in Molecular Dynamics

artículo científico publicado en 2015

Antinociceptive activity of new imidazolidine carbonyl derivatives. Part 4. Synthesis and pharmacological activity of 8-aryl-3,4-dioxo-2H,8H-6,7-dihydroimidazo[2,1-c] [1,2,4]triazines

artículo científico publicado en 2005

Application of Raman spectroscopy for direct analysis of Carlina acanthifolia subsp. utzka root essential oil.

artículo científico publicado en 2017

Autophagic cell death and premature senescence: New mechanism of 5-fluorouracil and sulforaphane synergistic anticancer effect in MDA-MB-231 triple negative breast cancer cell line.

artículo científico publicado en 2017

Biased agonism of clinically approved μ-opioid receptor agonists and TRV130 is not controlled by binding and signaling kinetics

scientific article published on 24 July 2019

Click chemistry for drug development and diverse chemical-biology applications.

artículo científico

Comparative molecular field analysis and molecular dynamics studies of the dopamine D2 receptor antagonists without a protonatable nitrogen atom.

artículo científico publicado en 2018

Comparison of retention of aromatic hydrocarbons with polar groups in binary reversed-phase high-performance liquid chromatography systems.

artículo científico publicado en 2002

Computational methods for studying G protein-coupled receptors (GPCRs).

artículo científico publicado en 2015

Corrigendum to 'Autophagic cell death and premature senescence: New mechanism of 5-fluorouracil and sulforaphane synergistic anticancer effect in MDA-MB-231 triple negative breast cancer cell line' Food Chem Toxicol. 111 (2018) 1-8

scientific article published on 04 May 2018

Crystal Structure of 1-(4-Chlorophenyl)-5(1H)-oxo-2,3-dihydroimidazo[1,2-a]-pyrimidine-6-carbonitrile

Determination of affinity and efficacy of acetylcholinesterase inhibitors using isothermal titration calorimetry.

artículo científico publicado en 2015

Discovery of nitroaryl urea derivatives with antiproliferative properties

artículo científico publicado en 2015

Distributed Drug Discovery, Part 2: global rehearsal of alkylating agents for the synthesis of resin-bound unnatural amino acids and virtual D(3) catalog construction.

artículo científico publicado en 2009

Effects of the Positive Allosteric Modulator of Metabotropic Glutamate Receptor 5, VU-29, on Maintenance Association between Environmental Cues and Rewarding Properties of Ethanol in Rats

artículo científico publicado en 2020

Electron ionisation induced fragmentation of ethyl 5(1H)-oxo- and 7(1H)-oxo-1-aryl-2,3-dihydroimidazo[1,2-a]-pyrimidine-6-carboxylates: evidence for an unusually regioselective rearrangement of M(+*) ions

artículo científico publicado en 2001

Electron ionization mass spectra of 8-aryl-3,4-dioxo-2H,8H-6,7-dihydroimidazo[2,1-c][1,2,4]triazines. Do they exhibit tautomerism in the gas phase?

artículo científico publicado en 2006

Electron ionization mass spectra of aryl- and benzyl-substituted 2,3-dihydroimidazo[1,2-a]pyrimidine-5,7(1H,6H)-diones.

artículo científico publicado en 2007

Experimental and computational studies on the tautomerism of N-substituted 3-amino-5-oxo-4-phenyl-1H-pyrazolo-1-carboxamides with antibacterial activity

Experimental and theoretical investigations on the keto–enol tautomerism of 4-substituted 3-[1-methylpyrrol-2-yl)methyl]-4,5-dihydro-1H-1,2,4-triazol-5-one derivatives

In Vitro Evaluation of Sulforaphane and a Natural Analog as Potent Inducers of 5-Fluorouracil Anticancer Activity

article published in 2018

Influence of carboxylic ion-pairing reagents on retention of peptides in thin-layer chromatography systems with C18 silica-based adsorbents

artículo científico publicado en 2016

Interplay between Two Allosteric Sites and Their Influence on Agonist Binding in Human μ Opioid Receptor

artículo científico publicado en 2016

Inversion of type of separation system in planar chromatography of peptides, using C18 silica-based adsorbents.

artículo científico publicado en 2016

Isothermal titration calorimetry in membrane protein research.

artículo científico

Microwave-assisted preparation, structural characterization, lipophilicity, and anti-cancer assay of some hydroxycoumarin derivatives.

artículo científico publicado en 2014

Modeling of glutamate GluR6 receptor and its interactions with novel noncompetitive antagonists

artículo científico publicado en 2009

Modeling the Active Conformation of Human µ Opioid Receptor

Molecular mechanisms of allosteric probe dependence in μ opioid receptor

artículo científico publicado en 2017

Molecular structure of ionotropic glutamate receptors.

artículo científico publicado en 2010

Non-peptide Opioid Receptor Ligands - Recent Advances. Part I - Agonists

Non-peptide opioid receptor ligands - recent advances. Part I - agonists

artículo científico publicado en 2002

Non-peptide opioid receptor ligands - recent advances. Part II - antagonists

artículo científico publicado en 2002

Novel Positive Allosteric Modulators of µ Opioid Receptor-Insight from In Silico and In Vivo Studies

artículo científico publicado en 2020

Nuclear estrogen receptors co-activation mechanisms

artículo científico publicado en 2013

Opportunities and Challenges in the Discovery of Allosteric Modulators of GPCRs

artículo científico publicado en 2018

Potential future of new glutamate agonists and antagonists development.

artículo científico publicado en 2018

Preferential Coupling of Dopamine D2S and D2L Receptor Isoforms with Gi1 and Gi2 Proteins-In Silico Study

artículo científico publicado en 2020

Protein-Protein Docking in Drug Design and Discovery.

artículo científico publicado en 2018

Recent Advances and Applications of Molecular Docking to G Protein-Coupled Receptors

artículo científico publicado en 2017

Role of N-terminus in function and dynamics of sirtuin 7: an in silico study

scientific article published on 26 April 2019

Signaling within Allosteric Machines: Signal Transmission Pathways Inside G Protein-Coupled Receptors.

artículo científico

Structural Studies on N-(1-naphthyl)-3-amino-5-oxo-4-phenyl-1Hpyrazole- 1-carboxamide with Antibacterial Activity

Structural and molecular docking studies of 4-benzyl-3-[(1-methylpyrrol- 2-yl)methyl]-4,5-dihydro-1H-1,2,4-triazol-5-one with anticancer activity

artículo científico publicado en 2013

Structural investigations of a series of 1,6-aryl-7-hydroxy-2,3-dihydroimidazo[1,2-a]pyrimidin-5(1H)-ones with potential antinociceptive activity

artículo científico publicado en 2015

Structural studies, homology modeling and molecular docking of novel non-competitive antagonists of GluK1/GluK2 receptors

artículo científico publicado en 2013

Structure-based virtual screening for novel inhibitors of Japanese encephalitis virus NS3 helicase/nucleoside triphosphatase

artículo científico publicado en 2009

Synthesis and Pharmacological Evaluation of Novel 1-(1,4-Alkylaryldisubstituted-4,5-dihydro-1H-imidazo)-3-substituted Urea Derivatives

artículo científico publicado en 2016

Synthesis and antiviral activity of 1-(1,3-disubstitutedimidazolidyn-2-ylidene)-3-ethoxycarbonylmethylurea derivatives

artículo científico publicado en 2015

Synthesis and molecular docking of indole and carbazole derivatives with potential pharmacological activity

scholarly article by Agnieszka Kaczor et al published 1 January 2014 in Heterocyclic Communications

Synthesis and molecular docking of novel non-competitive antagonists of GluK2 receptor

artículo científico publicado en 2014

Synthesis and pharmacological activity of new carbonyl derivatives of 1-aryl-2-iminoimidazolidine. Part 1. Synthesis and pharmacological activity of chain derivatives of 1-aryl-2-iminoimidazolidine containing urea moiety.

artículo científico publicado en 2001

Synthesis and pharmacological activity of new carbonyl derivatives of 1-aryl-2-iminoimidazolidine. Part 3. Synthesis and pharmacological activity of 1-aryl-5,6(1H)dioxo-2,3-dihydroimidazo[1,2-a]imidazoles

artículo científico publicado en 2002

Synthesis and pharmacological activity of new carbonyl derivatives of 1-aryl-2-iminoimidazolidine: part 2. Synthesis and pharmacological activity of 1,6-diaryl-5,7(1H)dioxo-2,3-dihydroimidazo[1,2-a][1,3,5]triazines.

artículo científico publicado en 2002

Synthesis of new 1-aryl-6-benzylimidazo[1,2-a][1,3,5]triazines with potential pharmacological activity

artículo científico publicado en 2012

Synthesis, Experimental and Computational Spectroscopic Studies, and Formation Thermodynamics of Diethyl [[2-(1-Aryl-4,5-dihydro-1H-imidazol- 2-yl)hydrazinyl]methylene]propanedioates

Synthesis, Structural Studies and Molecular Modelling of a Novel Imidazoline Derivative with Antifungal Activity.

artículo científico publicado en 2015

Synthesis, Structural and Thermal Studies of 3-(1-Benzyl-1,2,3,6-tetrahydropyridin-4-yl)-5-ethoxy-1-indole (D2AAK1_3) as Dopamine D₂ Receptor Ligand

artículo científico publicado en 2018

Synthesis, antiviral activity and structure-activity relationship of 1-(1-aryl-4,5-dihydro-1H-imidazoline)-3-chlorosulfonylureas and products of their cyclization.

artículo científico publicado en 2015

Synthesis, central nervous system activity and structure-activity relationship of N-substituted derivatives of 1-arylimidazolidyn-2-ylideneurea and products of their cyclization

artículo científico publicado en 2015

Synthesis, central nervous system activity and structure-activity relationships of novel 1-(1-Alkyl-4-aryl-4,5-dihydro-1H-imidazo)-3-substituted urea derivatives.

artículo científico publicado en 2015

Synthesis, central nervous system activity, and structure-activity relationship of 1-aryl-6-benzyl-7-hydroxy-2,3-dihydroimidazo[1,2-a]pyrimidine-5(1H)-ones

artículo científico publicado en 2014

Synthesis, in vitro and in vivo studies, and molecular modeling of N-alkylated dextromethorphan derivatives as non-competitive inhibitors of α3β4 nicotinic acetylcholine receptor

artículo científico publicado en 2014

Synthesis, pharmacological activity and molecular modeling of 1-aryl-7- hydroxy-2,3-dihydroimidazo[1,2-a]pyrimidine-5(1H)-ones and their 6-substituted derivatives.

artículo científico publicado en 2014

Synthesis, pharmacological and structural studies of 5-substituted-3-(1-arylmethyl-1,2,3,6-tetrahydropyridin-4-yl)-1H-indoles as multi-target ligands of aminergic GPCRs

artículo científico publicado en 2019

The Antipsychotic D2AAK1 as a Memory Enhancer for Treatment of Mental and Neurodegenerative Diseases

artículo científico publicado en 2020

The Universal 3D QSAR Model for Dopamine D2 Receptor Antagonists

scientific article published on 14 September 2019

The effect of statins on psoriasis severity: a meta-analysis of randomized clinical trials

artículo científico publicado en 2019

The pseudo-Michael reaction of 1-aryl-4,5-dihydro-1H-imidazol-2-amines with ethyl ethoxymethylenecyanoacetate

artículo científico publicado en 2013

The xanthophyll cycle pigments, violaxanthin and zeaxanthin, modulate molecular organization of the photosynthetic antenna complex LHCII.

artículo científico publicado en 2016

Theoretical studies on the structure and symmetry of the transmembrane region of glutamatergic GluR5 receptor

artículo científico publicado en 2008

Thyroid Peroxidase Activity is Inhibited by Phenolic Compounds-Impact of Interaction

artículo científico publicado en 2019

Toxicity of Carlina Oxide-A Natural Polyacetylene from the Carlina acaulis Roots-In Vitro and In Vivo Study

scientific article published on 09 April 2020

Tuning Down the Pain - an Overview of Allosteric Modulation of Opioid Receptors: Mechanisms of Modulation, Allosteric Sites, Modulator Syntheses.

artículo científico publicado en 2020

Use of binary and ternary mobile phases in reversed-phase high performance liquid chromatographic separation of chiral compounds

scientific article published on 01 March 2004

Usefulness of reversed-phase HPLC enriched with room temperature imidazolium based ionic liquids for lipophilicity determination of the newly synthesized analgesic active urea derivatives

artículo científico publicado en 2012

Lista de obras de Dariusz Matosiuk

1-(3-Chloro-phen-yl)-3-(1-p-tolyl-imidazolidin-2-yl-idene)urea

6-(2-Chloro-benz-yl)-1-(4-chloro-phen-yl)-7-hy-droxy-2,3-dihydro-1H-imidazo[1,2-a]pyrimidin-5-one.

Activation and Allosteric Modulation of Human μ Opioid Receptor in Molecular Dynamics

Antinociceptive activity of new imidazolidine carbonyl derivatives. Part 4. Synthesis and pharmacological activity of 8-aryl-3,4-dioxo-2H,8H-6,7-dihydroimidazo[2,1-c] [1,2,4]triazines

Application of Raman spectroscopy for direct analysis of Carlina acanthifolia subsp. utzka root essential oil.

Autophagic cell death and premature senescence: New mechanism of 5-fluorouracil and sulforaphane synergistic anticancer effect in MDA-MB-231 triple negative breast cancer cell line.

Biased agonism of clinically approved μ-opioid receptor agonists and TRV130 is not controlled by binding and signaling kinetics

Click chemistry for drug development and diverse chemical-biology applications.

Comparative molecular field analysis and molecular dynamics studies of the dopamine D2 receptor antagonists without a protonatable nitrogen atom.

Comparison of retention of aromatic hydrocarbons with polar groups in binary reversed-phase high-performance liquid chromatography systems.

Computational methods for studying G protein-coupled receptors (GPCRs).

Corrigendum to 'Autophagic cell death and premature senescence: New mechanism of 5-fluorouracil and sulforaphane synergistic anticancer effect in MDA-MB-231 triple negative breast cancer cell line' Food Chem Toxicol. 111 (2018) 1-8

Crystal Structure of 1-(4-Chlorophenyl)-5(1H)-oxo-2,3-dihydroimidazo[1,2-a]-pyrimidine-6-carbonitrile

Determination of affinity and efficacy of acetylcholinesterase inhibitors using isothermal titration calorimetry.

Discovery of nitroaryl urea derivatives with antiproliferative properties

Distributed Drug Discovery, Part 2: global rehearsal of alkylating agents for the synthesis of resin-bound unnatural amino acids and virtual D(3) catalog construction.

Effects of the Positive Allosteric Modulator of Metabotropic Glutamate Receptor 5, VU-29, on Maintenance Association between Environmental Cues and Rewarding Properties of Ethanol in Rats

Electron ionisation induced fragmentation of ethyl 5(1H)-oxo- and 7(1H)-oxo-1-aryl-2,3-dihydroimidazo[1,2-a]-pyrimidine-6-carboxylates: evidence for an unusually regioselective rearrangement of M(+*) ions

Electron ionization mass spectra of 8-aryl-3,4-dioxo-2H,8H-6,7-dihydroimidazo[2,1-c][1,2,4]triazines. Do they exhibit tautomerism in the gas phase?

Electron ionization mass spectra of aryl- and benzyl-substituted 2,3-dihydroimidazo[1,2-a]pyrimidine-5,7(1H,6H)-diones.

Experimental and computational studies on the tautomerism of N-substituted 3-amino-5-oxo-4-phenyl-1H-pyrazolo-1-carboxamides with antibacterial activity

Experimental and theoretical investigations on the keto–enol tautomerism of 4-substituted 3-[1-methylpyrrol-2-yl)methyl]-4,5-dihydro-1H-1,2,4-triazol-5-one derivatives

In Vitro Evaluation of Sulforaphane and a Natural Analog as Potent Inducers of 5-Fluorouracil Anticancer Activity

Influence of carboxylic ion-pairing reagents on retention of peptides in thin-layer chromatography systems with C18 silica-based adsorbents

Interplay between Two Allosteric Sites and Their Influence on Agonist Binding in Human μ Opioid Receptor

Inversion of type of separation system in planar chromatography of peptides, using C18 silica-based adsorbents.

Isothermal titration calorimetry in membrane protein research.

Microwave-assisted preparation, structural characterization, lipophilicity, and anti-cancer assay of some hydroxycoumarin derivatives.

Modeling of glutamate GluR6 receptor and its interactions with novel noncompetitive antagonists

Modeling the Active Conformation of Human µ Opioid Receptor

Molecular mechanisms of allosteric probe dependence in μ opioid receptor

Molecular structure of ionotropic glutamate receptors.

Non-peptide Opioid Receptor Ligands - Recent Advances. Part I - Agonists

Non-peptide opioid receptor ligands - recent advances. Part I - agonists

Non-peptide opioid receptor ligands - recent advances. Part II - antagonists

Novel Positive Allosteric Modulators of µ Opioid Receptor-Insight from In Silico and In Vivo Studies

Nuclear estrogen receptors co-activation mechanisms

Opportunities and Challenges in the Discovery of Allosteric Modulators of GPCRs

Potential future of new glutamate agonists and antagonists development.

Preferential Coupling of Dopamine D2S and D2L Receptor Isoforms with Gi1 and Gi2 Proteins-In Silico Study

Protein-Protein Docking in Drug Design and Discovery.

Recent Advances and Applications of Molecular Docking to G Protein-Coupled Receptors

Role of N-terminus in function and dynamics of sirtuin 7: an in silico study

Signaling within Allosteric Machines: Signal Transmission Pathways Inside G Protein-Coupled Receptors.

Structural Studies on N-(1-naphthyl)-3-amino-5-oxo-4-phenyl-1Hpyrazole- 1-carboxamide with Antibacterial Activity

Structural and molecular docking studies of 4-benzyl-3-[(1-methylpyrrol- 2-yl)methyl]-4,5-dihydro-1H-1,2,4-triazol-5-one with anticancer activity

Structural investigations of a series of 1,6-aryl-7-hydroxy-2,3-dihydroimidazo[1,2-a]pyrimidin-5(1H)-ones with potential antinociceptive activity

Structural studies, homology modeling and molecular docking of novel non-competitive antagonists of GluK1/GluK2 receptors

Structure-based virtual screening for novel inhibitors of Japanese encephalitis virus NS3 helicase/nucleoside triphosphatase

Synthesis and Pharmacological Evaluation of Novel 1-(1,4-Alkylaryldisubstituted-4,5-dihydro-1H-imidazo)-3-substituted Urea Derivatives

Synthesis and antiviral activity of 1-(1,3-disubstitutedimidazolidyn-2-ylidene)-3-ethoxycarbonylmethylurea derivatives

Synthesis and molecular docking of indole and carbazole derivatives with potential pharmacological activity

Synthesis and molecular docking of novel non-competitive antagonists of GluK2 receptor

Synthesis and pharmacological activity of new carbonyl derivatives of 1-aryl-2-iminoimidazolidine. Part 1. Synthesis and pharmacological activity of chain derivatives of 1-aryl-2-iminoimidazolidine containing urea moiety.

Synthesis and pharmacological activity of new carbonyl derivatives of 1-aryl-2-iminoimidazolidine. Part 3. Synthesis and pharmacological activity of 1-aryl-5,6(1H)dioxo-2,3-dihydroimidazo[1,2-a]imidazoles

Synthesis and pharmacological activity of new carbonyl derivatives of 1-aryl-2-iminoimidazolidine: part 2. Synthesis and pharmacological activity of 1,6-diaryl-5,7(1H)dioxo-2,3-dihydroimidazo[1,2-a][1,3,5]triazines.

Synthesis of new 1-aryl-6-benzylimidazo[1,2-a][1,3,5]triazines with potential pharmacological activity

Synthesis, Experimental and Computational Spectroscopic Studies, and Formation Thermodynamics of Diethyl [[2-(1-Aryl-4,5-dihydro-1H-imidazol- 2-yl)hydrazinyl]methylene]propanedioates

Synthesis, Structural Studies and Molecular Modelling of a Novel Imidazoline Derivative with Antifungal Activity.

Synthesis, Structural and Thermal Studies of 3-(1-Benzyl-1,2,3,6-tetrahydropyridin-4-yl)-5-ethoxy-1-indole (D2AAK1_3) as Dopamine D₂ Receptor Ligand

Synthesis, antiviral activity and structure-activity relationship of 1-(1-aryl-4,5-dihydro-1H-imidazoline)-3-chlorosulfonylureas and products of their cyclization.

Synthesis, central nervous system activity and structure-activity relationship of N-substituted derivatives of 1-arylimidazolidyn-2-ylideneurea and products of their cyclization

Synthesis, central nervous system activity and structure-activity relationships of novel 1-(1-Alkyl-4-aryl-4,5-dihydro-1H-imidazo)-3-substituted urea derivatives.

Synthesis, central nervous system activity, and structure-activity relationship of 1-aryl-6-benzyl-7-hydroxy-2,3-dihydroimidazo[1,2-a]pyrimidine-5(1H)-ones

Synthesis, in vitro and in vivo studies, and molecular modeling of N-alkylated dextromethorphan derivatives as non-competitive inhibitors of α3β4 nicotinic acetylcholine receptor

Synthesis, pharmacological activity and molecular modeling of 1-aryl-7- hydroxy-2,3-dihydroimidazo[1,2-a]pyrimidine-5(1H)-ones and their 6-substituted derivatives.

Synthesis, pharmacological and structural studies of 5-substituted-3-(1-arylmethyl-1,2,3,6-tetrahydropyridin-4-yl)-1H-indoles as multi-target ligands of aminergic GPCRs

The Antipsychotic D2AAK1 as a Memory Enhancer for Treatment of Mental and Neurodegenerative Diseases

The Universal 3D QSAR Model for Dopamine D2 Receptor Antagonists

The effect of statins on psoriasis severity: a meta-analysis of randomized clinical trials

The pseudo-Michael reaction of 1-aryl-4,5-dihydro-1H-imidazol-2-amines with ethyl ethoxymethylenecyanoacetate

The xanthophyll cycle pigments, violaxanthin and zeaxanthin, modulate molecular organization of the photosynthetic antenna complex LHCII.

Theoretical studies on the structure and symmetry of the transmembrane region of glutamatergic GluR5 receptor

Thyroid Peroxidase Activity is Inhibited by Phenolic Compounds-Impact of Interaction

Toxicity of Carlina Oxide-A Natural Polyacetylene from the Carlina acaulis Roots-In Vitro and In Vivo Study

Tuning Down the Pain - an Overview of Allosteric Modulation of Opioid Receptors: Mechanisms of Modulation, Allosteric Sites, Modulator Syntheses.

Use of binary and ternary mobile phases in reversed-phase high performance liquid chromatographic separation of chiral compounds

Usefulness of reversed-phase HPLC enriched with room temperature imidazolium based ionic liquids for lipophilicity determination of the newly synthesized analgesic active urea derivatives