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Lista de obras de Urban Lendahl

2015 Nobel Prize in Physiology or Medicine. Better health for millions of people thanks to drugs against parasites

artículo científico publicado en 2015

A 1.8kb GFAP-promoter fragment is active in specific regions of the embryonic CNS.

artículo científico publicado en 2001

A CADASIL-mutated Notch 3 receptor exhibits impaired intracellular trafficking and maturation but normal ligand-induced signaling.

artículo científico publicado en 2002

A critical role for Sox9 in notch-induced astrogliogenesis and stem cell maintenance

artículo científico publicado en 2013

A growing family of Notch ligands ⬇️

artículo científico publicado el 1 de febrero de 1998

A molecular atlas of cell types and zonation in the brain vasculature

artículo científico publicado en 2018

A nine-transmembrane domain topology for presenilin 1

artículo científico publicado en 2005

A rod end deletion in the intermediate filament protein nestin alters its subcellular localization in neuroepithelial cells of transgenic mice

artículo científico publicado en 1998

A sensitive and quantitative assay for measuring cleavage of presenilin substrates

artículo científico publicado en 2001

Abnormal reaction to central nervous system injury in mice lacking glial fibrillary acidic protein and vimentin

artículo científico publicado en 1999

Adult nestin-expressing subependymal cells differentiate to astrocytes in response to brain injury

artículo científico publicado en 1997

Altered Notch signaling resulting from expression of a WAMTP1-MAML2 gene fusion in mucoepidermoid carcinomas and benign Warthin's tumors

artículo científico publicado en 2004

Altered expression after expansion of a v-erbA transgene in transgenic mice

artículo científico publicado en 1995

Alzheimer's disease: presenilin 2-sparing γ-secretase inhibition is a tolerable Aβ peptide-lowering strategy

artículo científico publicado en 2012

An Eya1-Notch axis specifies bipotential epibranchial differentiation in mammalian craniofacial morphogenesis

artículo científico publicado en 2017

An evolutionarily conserved region in the second intron of the human nestin gene directs gene expression to CNS progenitor cells and to early neural crest cells

artículo científico publicado en 1997

Aph-1 interacts at the cell surface with proteins in the active gamma-secretase complex and membrane-tethered Notch.

artículo científico publicado en 2005

Author Correction: A molecular atlas of cell types and zonation in the brain vasculature

artículo científico publicado en 2018

Author Correction: Specification of CNS macrophage subsets occurs postnatally in defined niches

artículo científico publicado en 2022

BDNF regulates reelin expression and Cajal-Retzius cell development in the cerebral cortex

artículo científico publicado en 1998

Brain-derived neurotrophic factor expression in vivo is under the control of neuron-restrictive silencer element

artículo científico publicado en 1999

Canonical Notch signaling is dispensible for adult steady-state and stress myelo-erythropoiesis

artículo científico publicado en 2018

Cell surface antigen profiling using a novel type of antibody array immobilised to plasma ion-implanted polycarbonate

artículo científico publicado en 2014

Central nervous system stem cells in the embryo and adult

artículo científico publicado en 1998

Cerebrospinal fluid of newborn infants contains a deglycosylated form of the intermediate filament nestin

artículo científico publicado en 1996

Characterization of Notch3-deficient mice: normal embryonic development and absence of genetic interactions with a Notch1 mutation

artículo científico publicado en 2003

Characterization of intermediate steps in amyloid beta (Aβ) production under near-native conditions

artículo científico publicado en 2013

Cholangiopathies - Towards a molecular understanding

artículo científico publicado en 2018

Co-expressed presenilin 1 NTF and CTF form functional gamma-secretase complexes in cells devoid of full-length protein

artículo científico publicado en 2004

Coexpression of platelet-derived growth factor alpha and beta receptors on medulloblastomas and other primitive neuroectodermal tumors is consistent with an immature stem cell and neuronal derivation

artículo científico publicado en 1996

Colocalization of nestin and vimentin/desmin in skeletal muscle cells demonstrated by three-dimensional fluorescence digital imaging microscopy

artículo científico publicado en 1994

Combined expression of pTalpha and Notch3 in T cell leukemia identifies the requirement of preTCR for leukemogenesis

artículo científico publicado en 2002

Complementary and combinatorial patterns of Notch gene family expression during early mouse development

artículo científico publicado en 1995

Constitutive activation of NF-kappaB and T-cell leukemia/lymphoma in Notch3 transgenic mice

artículo científico publicado en 2000

Control of Notch-ligand endocytosis by ligand-receptor interaction

scientific article published on 01 September 2010

Corrigendum to "Cholangiopathies - Towards a molecular understanding" [EBioMedicine 35 (2018) 381-393]

artículo científico publicado en 2018

Cross-talk between notch and the estrogen receptor in breast cancer suggests novel therapeutic approaches

artículo científico publicado en 2008

Cross-talk between the Notch and TGF-beta signaling pathways mediated by interaction of the Notch intracellular domain with Smad3

artículo científico publicado en 2003

Decoding breast cancer tissue-stroma interactions using species-specific sequencing

artículo científico publicado en 2015

Delta-notch signaling in odontogenesis: correlation with cytodifferentiation and evidence for feedback regulation

artículo científico publicado en 1998

Differentiation and heterogeneity in T-antigen immortalized precursor cell lines from mouse cerebellum ⬇️

artículo científico publicado el 1 de diciembre de 1991

Distribution of nestin in the developing mouse limb bud in vivo and in micro-mass cultures of cells isolated from limb buds

artículo científico publicado en 1997

Domain-specific control of neurogenesis achieved through patterned regulation of Notch ligand expression

scientific journal article

E- and N-cadherin distribution in developing and functional human teeth under normal and pathological conditions

artículo científico publicado en 2002

Elevated expression levels of an Ig transgene in mice links the IgH 3' enhancer to the regulation of IgH expression

artículo científico publicado en 1996

Emerging links between cerebrovascular and neurodegenerative diseases-a special role for pericytes

scientific article published on 16 October 2019

Endogenous APP accumulates in synapses after BACE1 inhibition

artículo científico publicado en 2016

Evidence for dimeric BACE-mediated APP processing.

artículo científico publicado en 2010

Expression of Notch 1, 2 and 3 is regulated by epithelial-mesenchymal interactions and retinoic acid in the developing mouse tooth and associated with determination of ameloblast cell fate

artículo científico publicado en 1995

Expression of Trk receptors during cartilage differentiation

artículo científico publicado en 1996

Expression of activated Notch3 in transgenic mice enhances generation of T regulatory cells and protects against experimental autoimmune diabetes

artículo científico publicado en 2003

Expression of c-fos, tyrosine hydroxylase, and neuropeptide mRNA in the rat brain around birth: effects of hypoxia and hypothermia

artículo científico publicado en 1995

Expression of the Notch 3 intracellular domain in mouse central nervous system progenitor cells is lethal and leads to disturbed neural tube development

artículo científico publicado en 1996

Expression of the class VI intermediate filament nestin in human central nervous system tumors

artículo científico publicado en 1992

Expression of the intermediate filament nestin during rodent tooth development

artículo científico publicado en 1995

Expression of the intermediate filament nestin in gastrointestinal stromal tumors and interstitial cells of Cajal

artículo científico publicado en 2001

Expression pattern of notch1, 2 and 3 and Jagged1 and 2 in lymphoid and stromal thymus components: distinct ligand-receptor interactions in intrathymic T cell development

artículo científico publicado en 1999

Fetal ventral mesencephalon of human and rat origin maintained in vitro and transplanted to 6-hydroxydopamine-lesioned rats gives rise to grafts rich in dopaminergic neurons.

artículo científico publicado en 1996

Frequency and distribution of Notch mutations in tumor cell lines

artículo científico publicado en 2015

Functional Notch signaling is required for BMP4-induced inhibition of myogenic differentiation.

artículo científico publicado en 2003

Functional domains in presenilin 1: the Tyr-288 residue controls gamma-secretase activity and endoproteolysis

artículo científico publicado en 2004

Gene regulation in the formation of the central nervous system ⬇️

artículo científico publicado el 1 de julio de 1997

Generalized potential of adult neural stem cells

artículo científico publicado en 2000

Generating specificity and diversity in the transcriptional response to hypoxia

artículo científico publicado en 2009

Generation and phenotypic characterization of a galanin overexpressing mouse

scientific article published on 01 January 2005

Genetic breakthrough within neuroresearch. Notch 3-gene reveals hereditary multiinfarction dementia

artículo científico publicado en 1997

H-2 allele-specific protection from NK cell lysis in vitro for lymphoblasts but not tumor targets. Protection mediated by alpha 1/alpha 2 domains.

artículo científico publicado en 1994

H-2Dp transgene alters natural killer cell specificity at the target and effector cell levels. Comparison with an H-2Dd transgene

artículo científico publicado en 1996

High levels of Notch signaling down-regulate Numb and Numblike

artículo científico publicado en 2006

Human Fis1 regulates mitochondrial dynamics through inhibition of the fusion machinery

artículo científico publicado en 2019

Human MIEF1 recruits Drp1 to mitochondrial outer membranes and promotes mitochondrial fusion rather than fission

artículo científico publicado en 2011

Hypo- and hyperactivated Notch signaling induce a glycolytic switch through distinct mechanisms.

artículo científico publicado en 2011

Hypoxia requires notch signaling to maintain the undifferentiated cell state

artículo científico publicado en 2005

Hypoxia-induced arterial differentiation requires adrenomedullin and notch signaling

artículo científico publicado en 2013

Identification of a neural stem cell in the adult mammalian central nervous system

artículo científico publicado en 1999

Identification of both general and region-specific embryonic CNS enhancer elements in the nestin promoter

artículo científico publicado en 1999

Identification of brain-derived neurotrophic factor promoter regions mediating tissue-specific, axotomy-, and neuronal activity-induced expression in transgenic mice

artículo científico publicado en 1995

Immunohistochemical detection of nestin in pediatric brain tumors.

artículo científico publicado en 2002

Induction of astrocytic nestin expression by depolarization in rats

artículo científico publicado en 2001

Influence of glycosylphosphatidylinositol-linked H-2Dd molecules on target cell protection and natural killer cell specificity in transgenic mice

artículo científico publicado en 1996

Interaction with factor inhibiting HIF-1 defines an additional mode of cross-coupling between the Notch and hypoxia signaling pathways

artículo científico publicado en 2008

Interactions between Notch- and hypoxia-induced transcriptomes in embryonic stem cells

article published in 2010

Intermediate Filament Nestin is Present in the Cerebrospinal Fluid of Children. 97

artículo científico publicado en 1996

Ion fluxes and neurotransmitters signaling in neural development

artículo científico publicado en 2008

Limb proprioceptive deficits without neuronal loss in transgenic mice overexpressing neurotrophin-3 in the developing nervous system

Lorenz Poellinger MD, PhD (1957-2016).

artículo científico publicado en 2017

Loss of CSL Unlocks a Hypoxic Response and Enhanced Tumor Growth Potential in Breast Cancer Cells

artículo científico publicado en 2016

Ly49A expression on T cells alters T cell selection

scientific article published on 01 February 2000

MHC class I mosaic mice reveal insights into control of Ly49C inhibitory receptor expression in NK cells

article

MHC class I-Ly49 interactions shape the Ly49 repertoire on murine NK cells

artículo científico publicado en 2001

MIEF1/2 function as adaptors to recruit Drp1 to mitochondria and regulate the association of Drp1 with Mff.

artículo científico publicado en 2017

Mice carrying a R142C Notch 3 knock-in mutation do not develop a CADASIL-like phenotype

artículo científico publicado en 2005

Mice over-expressing galanin have elevated heat nociceptive threshold

artículo científico publicado en 2001

Microdialysis in freely moving mice: determination of acetylcholine, serotonin and noradrenaline release in galanin transgenic mice.

artículo científico publicado en 2001

Mitotic reorganization of the intermediate filament protein nestin involves phosphorylation by cdc2 kinase

artículo científico publicado en 2001

Modelling cell lineage using a meta-Boolean tree model with a relation to gene regulatory networks.

artículo científico publicado en 2010

Modulating Notch signaling by pathway-intrinsic and pathway-extrinsic mechanisms.

artículo científico publicado en 2008

Modulation of vascular gene expression by hypoxia

artículo científico publicado en 2007

Motch A and motch B--two mouse Notch homologues coexpressed in a wide variety of tissues

artículo científico publicado en 1993

Mouse Model of Alagille Syndrome and Mechanisms of Jagged1 Missense Mutations.

artículo científico publicado en 2017

Mouse Notch 3 expression in the pre- and postnatal brain: relationship to the stroke and dementia syndrome CADASIL.

artículo científico publicado en 2002

Mouse Serrate-1 (Jagged-1): expression in the developing tooth is regulated by epithelial-mesenchymal interactions and fibroblast growth factor-4.

artículo científico publicado en 1997

Mouse Serrate-1 and Notch genes differ in their response to signaling molecules during odontogenesis

artículo científico publicado en 1996

Nestin distribution in the developing limb bud in vivo and in vitro

artículo científico publicado en 1996

Nestin enhancer requirements for expression in normal and injured adult CNS.

artículo científico publicado en 2002

Nestin expression in embryonic and adult human teeth under normal and pathological conditions

artículo científico publicado en 2000

Nestin expression is lost in a neural stem cell line through a mechanism involving the proteasome and Notch signalling

artículo científico publicado en 2004

Nestin mRNA expression correlates with the central nervous system progenitor cell state in many, but not all, regions of developing central nervous system

artículo científico publicado en 1995

Non-canonical Notch signaling activates IL-6/JAK/STAT signaling in breast tumor cells and is controlled by p53 and IKKα/IKKβ.

artículo científico publicado en 2012

Notch -- a goldilocks signaling pathway in disease and cancer therapy

artículo científico publicado en 2016

Notch Signaling in Development, Tissue Homeostasis, and Disease

artículo científico publicado en 2017

Notch and Wnt Dysregulation and Its Relevance for Breast Cancer and Tumor Initiation

scientific article published on 01 November 2018

Notch and neurogenesis

artículo científico publicado en 1998

Notch and the birth of glial cells

artículo científico publicado en 2001

Notch induces cyclin-D1-dependent proliferation during a specific temporal window of neural differentiation in ES cells.

artículo científico publicado en 2010

Notch receptor cleavage depends on but is not directly executed by presenilins

artículo científico publicado en 2002

Notch signaling and its integration with other signaling mechanisms.

artículo científico publicado en 2006

Notch signaling in development and disease.

artículo científico publicado en 2004

Notch signaling induces SKP2 expression and promotes reduction of p27Kip1 in T-cell acute lymphoblastic leukemia cell lines

artículo científico publicado en 2007

Notch signaling maintains neural rosette polarity

artículo científico publicado en 2013

Notch signaling mediates hypoxia-induced tumor cell migration and invasion

artículo científico publicado en 2008

Notch signaling promotes a HIF2α-driven hypoxic response in multiple tumor cell types

article published in 2018

Notch signaling regulates platelet-derived growth factor receptor-beta expression in vascular smooth muscle cells.

artículo científico publicado en 2008

Notch signaling: simplicity in design, versatility in function ⬇️

artículo científico publicado el 1 de septiembre de 2011

Notch signalling controls pancreatic cell differentiation

scientific journal article

Notch signalling regulates epibranchial placode patterning and segregation

scientific article published on 17 February 2020

Notch-1 associates with IKKalpha and regulates IKK activity in cervical cancer cells.

artículo científico publicado en 2008

Notch-related genes in animal development.

artículo científico publicado en 1995

Notch1 signaling promotes neuro-ectodermal differentiation of embryonic stem cells via the Notch target gene Sox9

artículo científico publicado en 2010

Notch2 protein distribution in human teeth under normal and pathological conditions

artículo científico publicado en 2003

Notch3 is necessary for blood vessel integrity in the central nervous system

artículo científico publicado en 2014

Numblike and Numb differentially affect p53 and Sonic Hedgehog signaling

artículo científico publicado en 2011

Oh no, Notch again!

artículo científico publicado en 2001

PKCζ regulates Notch receptor routing and activity in a Notch signaling-dependent manner

artículo científico publicado en 2014

Patterns of nestin and other intermediate filament expression distinguish between gastrointestinal stromal tumors, leiomyomas and schwannomas

scientific article published on 01 June 2002

Pediatric rhabdomyosarcomas express the intermediate filament nestin

artículo científico publicado en 1998

Pen-2 is sequestered in the endoplasmic reticulum and subjected to ubiquitylation and proteasome-mediated degradation in the absence of presenilin

artículo científico publicado en 2004

Phosphorylation of Notch1 by Pim kinases promotes oncogenic signaling in breast and prostate cancer cells.

artículo científico publicado en 2016

Publisher Correction: Single-cell analysis uncovers fibroblast heterogeneity and criteria for fibroblast and mural cell identification and discrimination

artículo científico publicado en 2020

Rapid, widespread, and longlasting induction of nestin contributes to the generation of glial scar tissue after CNS injury

artículo científico publicado en 1995

Recording Notch signaling in real time.

artículo científico publicado en 2006

Regenerative medicine for the treatment of heart disease

artículo científico publicado en 2013

Regenerative medicine: a 2009 overview

artículo científico publicado en 2009

Regulation of mitochondrial dynamics: convergences and divergences between yeast and vertebrates

artículo científico

Regulatory region in choline acetyltransferase gene directs developmental and tissue-specific expression in transgenic mice

artículo científico publicado en 1995

Retinoid-X receptor signalling in the developing spinal cord

artículo científico publicado en 1998

Revisiting the peripheral sink hypothesis: inhibiting BACE1 activity in the periphery does not alter β-amyloid levels in the CNS.

artículo científico publicado en 2014

Role of Islet1 in the patterning of murine dentition

scientific journal article

Role of NOTCH3 Mutations in the Cerebral Small Vessel Disease Cerebral Autosomal Dominant Arteriopathy With Subcortical Infarcts and Leukoencephalopathy

artículo científico publicado en 2018

Single-cell RNA sequencing of mouse brain and lung vascular and vessel-associated cell types

artículo científico publicado en 2018

Single-cell analysis uncovers fibroblast heterogeneity and criteria for fibroblast and mural cell identification and discrimination

artículo científico publicado en 2020

SoxB1 transcription factors and Notch signaling use distinct mechanisms to regulate proneural gene function and neural progenitor differentiation

artículo científico publicado en 2008

Specific and innervation-regulated expression of the intermediate filament protein nestin at neuromuscular and myotendinous junctions in skeletal muscle

artículo científico publicado en 1999

Specification of CNS macrophage subsets occurs postnatally in defined niches

artículo científico publicado en 2022

Structural and functional characterization of the rat neurotrophin-4 gene

artículo científico publicado en 1997

Suppressed kindling epileptogenesis in mice with ectopic overexpression of galanin ⬇️

artículo científico publicado el 6 de noviembre de 2001

Sydney Brenner, Robert Horvitz and John Sulston. Winners of the 2002 Nobel Prize in medicine or physiology. Genetic regulation of organ development and programmed cell death

artículo científico publicado en 2002

THE EMBRYONIC INTERMEDIATE FILAMENT PROTEIN NESTIN IS PRESENT IN THE CEREBROSPINAL FLUID OF NICU INFANTS. † 2223

artículo científico publicado en 1996

Targeted expression of a multifunctional chimeric neurotrophin in the lesioned sciatic nerve accelerates regeneration of sensory and motor axons

artículo científico publicado en 1998

The European dimension for the mouse genome mutagenesis program

artículo científico publicado en 2004

The Notch intracellular domain is ubiquitinated and negatively regulated by the mammalian Sel-10 homolog

artículo científico publicado en 2001

The expression of intermediate filament protein nestin as related to vimentin and desmin in regenerating skeletal muscle

artículo científico publicado en 2001

The intermediate filament protein nestin occurs transiently in differentiating testis of rat and mouse

artículo científico publicado en 1997

The interplay between the cellular hypoxic response and Notch signaling

artículo científico publicado en 2017

The mitochondrial elongation factors MIEF1 and MIEF2 exert partially distinct functions in mitochondrial dynamics.

artículo científico publicado en 2013

The notch 3 intracellular domain represses notch 1-mediated activation through Hairy/Enhancer of split (HES) promoters

artículo científico publicado en 1999

The novel conserved mitochondrial inner-membrane protein MTGM regulates mitochondrial morphology and cell proliferation

artículo científico publicado en 2009

The origin of the ankyrin repeat region in Notch intracellular domains is critical for regulation of HES promoter activity

artículo científico publicado en 2001

The tumor suppressor gene hCDC4 is frequently mutated in human T-cell acute lymphoblastic leukemia with functional consequences for Notch signaling

artículo científico publicado en 2007

Therapeutic modulation of Notch signalling--are we there yet?

artículo científico

Thyroid abnormalities and hepatocellular carcinoma in mice transgenic for v-erbA.

artículo científico publicado en 1994

Transgenic analysis of central nervous system development and regeneration ⬇️

artículo científico publicado el 1 de enero de 1997

YB-1 acts as a ligand for Notch-3 receptors and modulates receptor activation

artículo científico publicado en 2009

[Dedifferentiation of specialized cells. New way open for cell therapy and regenerative medicine]

scientific article published on 01 May 2008

gamma-Secretase complexes containing N- and C-terminal fragments of different presenilin origin retain normal gamma-secretase activity

artículo científico publicado en 2005

p300 and PCAF act cooperatively to mediate transcriptional activation from chromatin templates by notch intracellular domains in vitro

artículo científico publicado en 2002

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