Lista de obras - Monther A Khanfar - Dominio Público Uruguay

3D-QSAR studies of latrunculin-based actin polymerization inhibitors using CoMFA and CoMSIA approaches ⬇️

artículo científico publicado el 12 de mayo de 2010

4-(4-Chloro-phen-yl)-1-(2-hydr-oxy-2,2-di-phenyl-acet-yl)thio-semicarbazide.

artículo científico publicado en 2008

A New Eudesmane Type Sesquiterpene from Inula Viscosa ⬇️

artículo científico publicado el 1 de abril de 2003

A prodrug approach to enhance azelaic acid percutaneous availability.

artículo científico publicado en 2016

Bioactive natural, biocatalytic, and semisynthetic tobacco cembranoids.

artículo científico publicado en 2010

Combining docking-based comparative intermolecular contacts analysis and k-nearest neighbor correlation for the discovery of new check point kinase 1 inhibitors

artículo científico publicado en 2015

Computer-aided discovery of new FGFR-1 inhibitors followed by in vitro validation.

artículo científico publicado en 2016

Design and Evaluation of 3-(Benzylthio)benzamide Derivatives as Potent and Selective SIRT2 Inhibitors

artículo científico publicado en 2015

Design of semisynthetic analogues and 3D-QSAR study of eunicellin-based diterpenoids as prostate cancer migration and invasion inhibitors.

artículo científico publicado en 2011

Development and characterization of 3-(benzylsulfonamido)benzamides as potent and selective SIRT2 inhibitors

artículo científico publicado en 2014

Diaryldichalcogenide radical cations.

artículo científico publicado en 2014

Discovery of Novel GSK-3β Inhibitors with Potent in Vitro and in Vivo Activities and Excellent Brain Permeability Using Combined Ligand- and Structure-Based Virtual Screening ⬇️

artículo científico publicado el 17 de noviembre de 2010

Discovery of Potent Bruton's Tyrosine Kinase Inhibitors Using Ligand Based Modeling.

artículo científico publicado en 2016

Discovery of nanomolar phosphoinositide 3-kinase gamma (PI3Kγ) inhibitors using ligand-based modeling and virtual screening followed by in vitro analysis.

artículo científico publicado en 2014

Discovery of new heat shock protein 90 inhibitors using virtual co-crystallized pharmacophore generation

artículo científico publicado en 2016

Discovery of novel urokinase plasminogen activator (uPA) inhibitors using ligand-based modeling and virtual screening followed by in vitro analysis.

artículo científico publicado en 2014

Discovery of potent NEK2 inhibitors as potential anticancer agents using structure-based exploration of NEK2 pharmacophoric space coupled with QSAR analyses

artículo científico publicado en 2016

Discovery of potent adenosine A2a antagonists as potential anti-Parkinson disease agents. Non-linear QSAR analyses integrated with pharmacophore modeling

artículo científico publicado en 2016

Discovery of potent polyphosphate kinase 1 (PPK1) inhibitors using structure-based exploration of PPK1Pharmacophoric space coupled with docking analyses.

artículo científico publicado en 2018

Discovery, design, and synthesis of anti-metastatic lead phenylmethylene hydantoins inspired by marine natural products.

artículo científico publicado en 2008

Divergent Strategy for Diastereocontrolled Synthesis of Small- and Medium-Ring Architectures

artículo científico publicado en 2020

Elaborate ligand-based modeling coupled with multiple linear regression and k nearest neighbor QSAR analyses unveiled new nanomolar mTOR inhibitors.

artículo científico publicado en 2013

Gas chromatography/trace analysis of derivatized azelaic acid as a stability marker ⬇️

artículo científico publicado el 21 de agosto de 2013

Halogenated benzene cation radicals.

artículo científico publicado en 2012

Marine sponge-derived sipholane triterpenoids reverse P-glycoprotein (ABCB1)-mediated multidrug resistance in cancer cells

artículo científico publicado en 2010

Methods for evaluation of structural and biological properties of antiinvasive natural products.

artículo científico publicado en 2011

Multidirectional desymmetrization of pluripotent building block en route to diastereoselective synthesis of complex nature-inspired scaffolds

artículo científico publicado en 2018

One-Pot Synthesis of Diverse Collections of Benzoxazepine and Indolopyrazine Fused to Heterocyclic Systems

artículo científico publicado en 2019

Pharmacophore modeling, homology modeling, and in silico screening reveal mammalian target of rapamycin inhibitory activities for sotalol, glyburide, metipranolol, sulfamethizole, glipizide, and pioglitazone.

artículo científico publicado en 2013

Phenylmethylene hydantoins as prostate cancer invasion and migration inhibitors. CoMFA approach and QSAR analysis.

artículo científico publicado en 2010

Protective activity of (1S,2E,4R,6R,7E,11E)-2,7,11-cembratriene-4,6-diol analogues against diisopropylfluorophosphate neurotoxicity: preliminary structure-activity relationship and pharmacophore modeling.

scientific article published on 24 May 2013

Rational design and semisynthesis of betulinic acid analogues as potent topoisomerase inhibitors.

artículo científico publicado en 2009

Sequencing [4 + 1]-Cycloaddition and Aza-Michael Addition Reactions: A Diastereoselective Cascade for the Rapid Access of Pyrido[2',1':2,3]/Thiazolo[2',3':2,3]imidazo[1,5-a]quinolone Scaffolds as Potential Antibacterial and Anticancer Motifs

scientific article published on 31 October 2019

Synthesis and characterization of new derivatives of alginic acid and evaluation of their iron(III)-crosslinked beads as potential controlled release matrices

artículo científico publicado en 2013

Synthesis, Characterization and Biological Evaluation of Metal Adamantyl 2-Pyridylhydrazone Complexes

artículo científico publicado en 2020

Synthesis, Characterization, Crystal Structure, and DFT Study of a New Square Planar Cu(II) Complex Containing Bulky Adamantane Ligand.

artículo científico publicado en 2018

Three new seco-ursadiene triterpenoids from Salvia syriaca

artículo científico publicado en 2014

Unsupervised pharmacophore modeling combined with QSAR analyses revealed novel low micromolar SIRT2 inhibitors.

artículo científico publicado en 2017

Lista de obras de Monther A Khanfar

3D-QSAR studies of latrunculin-based actin polymerization inhibitors using CoMFA and CoMSIA approaches ⬇️

4-(4-Chloro-phen-yl)-1-(2-hydr-oxy-2,2-di-phenyl-acet-yl)thio-semicarbazide.

A New Eudesmane Type Sesquiterpene from Inula Viscosa ⬇️

A prodrug approach to enhance azelaic acid percutaneous availability.

Bioactive natural, biocatalytic, and semisynthetic tobacco cembranoids.

Combining docking-based comparative intermolecular contacts analysis and k-nearest neighbor correlation for the discovery of new check point kinase 1 inhibitors

Computer-aided discovery of new FGFR-1 inhibitors followed by in vitro validation.

Design and Evaluation of 3-(Benzylthio)benzamide Derivatives as Potent and Selective SIRT2 Inhibitors

Design of semisynthetic analogues and 3D-QSAR study of eunicellin-based diterpenoids as prostate cancer migration and invasion inhibitors.

Development and characterization of 3-(benzylsulfonamido)benzamides as potent and selective SIRT2 inhibitors

Diaryldichalcogenide radical cations.

Discovery of Novel GSK-3β Inhibitors with Potent in Vitro and in Vivo Activities and Excellent Brain Permeability Using Combined Ligand- and Structure-Based Virtual Screening ⬇️

Discovery of Potent Bruton's Tyrosine Kinase Inhibitors Using Ligand Based Modeling.

Discovery of nanomolar phosphoinositide 3-kinase gamma (PI3Kγ) inhibitors using ligand-based modeling and virtual screening followed by in vitro analysis.

Discovery of new heat shock protein 90 inhibitors using virtual co-crystallized pharmacophore generation

Discovery of novel urokinase plasminogen activator (uPA) inhibitors using ligand-based modeling and virtual screening followed by in vitro analysis.

Discovery of potent NEK2 inhibitors as potential anticancer agents using structure-based exploration of NEK2 pharmacophoric space coupled with QSAR analyses

Discovery of potent adenosine A2a antagonists as potential anti-Parkinson disease agents. Non-linear QSAR analyses integrated with pharmacophore modeling

Discovery of potent polyphosphate kinase 1 (PPK1) inhibitors using structure-based exploration of PPK1Pharmacophoric space coupled with docking analyses.

Discovery, design, and synthesis of anti-metastatic lead phenylmethylene hydantoins inspired by marine natural products.

Divergent Strategy for Diastereocontrolled Synthesis of Small- and Medium-Ring Architectures

Elaborate ligand-based modeling coupled with multiple linear regression and k nearest neighbor QSAR analyses unveiled new nanomolar mTOR inhibitors.

Gas chromatography/trace analysis of derivatized azelaic acid as a stability marker ⬇️

Halogenated benzene cation radicals.

Marine sponge-derived sipholane triterpenoids reverse P-glycoprotein (ABCB1)-mediated multidrug resistance in cancer cells

Methods for evaluation of structural and biological properties of antiinvasive natural products.

Multidirectional desymmetrization of pluripotent building block en route to diastereoselective synthesis of complex nature-inspired scaffolds

One-Pot Synthesis of Diverse Collections of Benzoxazepine and Indolopyrazine Fused to Heterocyclic Systems

Pharmacophore modeling, homology modeling, and in silico screening reveal mammalian target of rapamycin inhibitory activities for sotalol, glyburide, metipranolol, sulfamethizole, glipizide, and pioglitazone.

Phenylmethylene hydantoins as prostate cancer invasion and migration inhibitors. CoMFA approach and QSAR analysis.

Protective activity of (1S,2E,4R,6R,7E,11E)-2,7,11-cembratriene-4,6-diol analogues against diisopropylfluorophosphate neurotoxicity: preliminary structure-activity relationship and pharmacophore modeling.

Rational design and semisynthesis of betulinic acid analogues as potent topoisomerase inhibitors.

Sequencing [4 + 1]-Cycloaddition and Aza-Michael Addition Reactions: A Diastereoselective Cascade for the Rapid Access of Pyrido[2',1':2,3]/Thiazolo[2',3':2,3]imidazo[1,5-a]quinolone Scaffolds as Potential Antibacterial and Anticancer Motifs

Synthesis and characterization of new derivatives of alginic acid and evaluation of their iron(III)-crosslinked beads as potential controlled release matrices

Synthesis, Characterization and Biological Evaluation of Metal Adamantyl 2-Pyridylhydrazone Complexes

Synthesis, Characterization, Crystal Structure, and DFT Study of a New Square Planar Cu(II) Complex Containing Bulky Adamantane Ligand.

Three new seco-ursadiene triterpenoids from Salvia syriaca

Unsupervised pharmacophore modeling combined with QSAR analyses revealed novel low micromolar SIRT2 inhibitors.