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Lista de obras de Huda Akil

3xTg-AD Mice Exhibit an Activated Central Stress Axis During Early-Stage Pathology ⬇️

artículo científico publicado el 1 de enero de 2013

A 6-hydroxydopamine lesion of the mesostriatal dopamine system decreases the expression of corticotropin releasing hormone and neurotensin mRNAs in the amygdala and bed nucleus of the stria terminalis.

artículo científico publicado en 2002

A new role for FGF2 as an endogenous inhibitor of anxiety

artículo científico publicado en 2009

A selective role for dopamine in stimulus-reward learning

artículo científico publicado en 2010

A task to manipulate attentional load, set-shifting, and inhibitory control: convergent validity and test-retest reliability of the Parametric Go/No-Go Test

artículo científico publicado en 2006

Adaptation to single housing is dynamic: Changes in hormone levels, gene expression, signaling in the brain, and anxiety-like behavior in adult male C57Bl/6J mice

artículo científico publicado en 2019

Adolescent cocaine exposure enhances goal-tracking behavior and impairs hippocampal cell genesis selectively in adult bred low-responder rats

artículo científico publicado en 2017

Altered DNA Methylation in the Developing Brains of Rats Genetically Prone to High versus Low Anxiety

scientific article published on 25 January 2019

Altered choroid plexus gene expression in major depressive disorder

artículo científico publicado en 2014

Amphetamine-evoked c-fos mRNA expression in the caudate-putamen: the effects of DA and NMDA receptor antagonists vary as a function of neuronal phenotype and environmental context.

artículo científico publicado en 2003

Amphetamine-induced c-fos mRNA expression in the caudate-putamen and subthalamic nucleus: interactions between dose, environment, and neuronal phenotype

artículo científico publicado en 2003

An animal model of genetic vulnerability to behavioral disinhibition and responsiveness to reward-related cues: implications for addiction.

artículo científico publicado en 2010

Analysis of miR-137 expression and rs1625579 in dorsolateral prefrontal cortex

scientific article published on 17 June 2013

Analyzing gene expression in depression.

artículo científico publicado en 2009

Anatomical and biochemical studies of the opioid peptides and related substances in the brain

Antecedents and consequences of drug abuse in rats selectively bred for high and low response to novelty ⬇️

artículo científico publicado el 29 de abril de 2013

Antidepressant-like effects of intracerebroventricular FGF2 in rats

artículo científico publicado en 2008

Application of microarray technology in primate behavioral neuroscience research

artículo científico publicado en 2006

Basal microRNA expression patterns in reward circuitry of selectively bred high-responder and low-responder rats vary by brain region and genotype

artículo científico publicado en 2014

Behavioral Neurochemistry: Neuroregulators and Behavioral States ⬇️

artículo científico publicado el 26 de mayo de 1978

Beta1 adrenergic receptors in the bed nucleus of stria terminalis mediate differential responses to opiate withdrawal

artículo científico publicado en 2006

Binding and GTPgammaS autoradiographic analysis of preproorphanin precursor peptide products at the ORL1 and opioid receptors

artículo científico publicado en 2003

Blockade of the cholecystokinin CCK-2 receptor prevents the normalization of anxiety levels in the rat

scientific article published on 14 September 2019

Bruce McEwen, 1938-2020

scientific article published on 11 March 2020

Building Bridges through Science.

artículo científico publicado en 2017

CREB deficient mice show inhibition and low activity in novel environments without changes in stress reactivity

artículo científico publicado en 2004

Challenges and opportunities in mining neuroscience data

artículo científico publicado en 2011

Chronic stress in adolescence differentially affects cocaine vulnerability in adulthood in a selectively bred rat model of individual differences: role of accumbal dopamine signaling

artículo científico publicado en 2020

Circadian patterns of gene expression in the human brain and disruption in major depressive disorder

artículo científico publicado en 2013

Cocaine Withdrawal Causes Delayed Dysregulation of Stress Genes in the Hippocampus ⬇️

artículo científico publicado el 30 de julio de 2012

Cocaine interacts with the novelty-seeking trait to modulate FGFR1 gene expression in the rat.

artículo científico publicado en 2008

Cognitive Control as a 5-HT-Based Domain That Is Disrupted in Major Depressive Disorder

scholarly article by Scott A Langenecker et al published 2019 in Frontiers in Psychology

Cognitive performance is highly sensitive to prior experience in mice with a learning and memory deficit: failure leads to more failure

artículo científico publicado en 2005

Colocalization of estrogen β-receptor messenger RNA with orphanin FQ, vasopressin and oxytocin in the rat hypothalamic paraventricular and supraoptic nuclei ⬇️

artículo científico publicado el 11 de abril de 2003

Combining laser capture microdissection with quantitative real-time PCR: effects of tissue manipulation on RNA quality and gene expression

artículo científico publicado en 2005

Connective Tissue Growth Factor Is a Novel Prodepressant

article

Correlation of estrogen beta-receptor messenger RNA with endogenous levels of plasma estradiol and progesterone in the female rat hypothalamus, the bed nucleus of stria terminalis and the medial amygdala

artículo científico publicado en 2002

DNA Methylation in the Developing Hippocampus and Amygdala of Anxiety-Prone versus Risk-Taking Rats ⬇️

artículo científico publicado el 8 de mayo de 2012

Decreased proliferation of adult hippocampal stem cells during cocaine withdrawal: possible role of the cell fate regulator FADD.

artículo científico

Delayed effects of chronic variable stress during peripubertal-juvenile period on hippocampal morphology and on cognitive and stress axis functions in rats

artículo científico publicado en 2004

Determinants of ligand selectivity at the kappa-receptor based on the structure of the orphanin FQ receptor

artículo científico publicado en 2002

Developmental underpinnings of differences in rodent novelty-seeking and emotional reactivity

artículo científico publicado en 2011

Distinct populations of presympathetic-premotor neurons express orexin or melanin-concentrating hormone in the rat lateral hypothalamus.

artículo científico publicado en 2007

Diurnal rhythm of agouti-related protein and its relation to corticosterone and food intake

artículo científico publicado en 2002

Diurnal rhythmic expression of the rhythm-related genes, rPeriod1, rPeriod2, and rClock, in the rat brain

artículo científico publicado en 2005

Dysregulated fibroblast growth factor (FGF) signaling in neurological and psychiatric disorders

artículo científico

Early-Life Forebrain Glucocorticoid Receptor Overexpression Increases Anxiety Behavior and Cocaine Sensitization ⬇️

artículo científico publicado el 27 de agosto de 2011

Effect of agonal and postmortem factors on gene expression profile: quality control in microarray analyses of postmortem human brain

artículo científico publicado en 2004

Effect of cocaine on Fas-associated protein with death domain in the rat brain: individual differences in a model of differential vulnerability to drug abuse

scientific journal article

Effects of a selectively bred novelty-seeking phenotype on the motivation to take cocaine in male and female rats

artículo científico publicado en 2011

Effects of early-life FGF2 on ultrasonic vocalizations (USVs) and the mu-opioid receptor in male Sprague-Dawley rats selectively-bred for differences in their response to novelty

artículo científico publicado en 2019

Endogenous Opioids at the Intersection of Opioid Addiction, Pain, and Depression: The Search for a Precision Medicine Approach

scientific article published on 28 February 2020

Evaluation of Affymetrix Gene Chip sensitivity in rat hippocampal tissue using SAGE analysis. Serial Analysis of Gene Expression

artículo científico publicado en 2002

Evidence for alterations of the glial syncytial function in major depressive disorder

artículo científico publicado en 2015

Evidence for transcriptional factor dysregulation in the dorsal raphe nucleus of patients with major depressive disorder.

artículo científico publicado en 2012

Evidence of allelic imbalance in the schizophrenia susceptibility gene ZNF804A in human dorsolateral prefrontal cortex

artículo científico publicado en 2013

Evolving gene/transcript definitions significantly alter the interpretation of GeneChip data

artículo científico publicado en 2005

Exon expression in lymphoblastoid cell lines from subjects with schizophrenia before and after glucose deprivation.

artículo científico publicado en 2009

Exploratory locomotion, a predictor of addiction vulnerability, is oligogenic in rats selected for this phenotype

scientific article published on 10 June 2019

Expression of c-fos gene activation during rough and tumble play in juvenile rats

artículo científico publicado en 2002

Expression patterns of corticotropin-releasing factor, arginine vasopressin, histidine decarboxylase, melanin-concentrating hormone, and orexin genes in the human hypothalamus.

artículo científico publicado en 2010

FGF2 is a target and a trigger of epigenetic mechanisms associated with differences in emotionality: partnership with H3K9me3.

artículo científico publicado en 2014

Fibroblast Growth Factor 2 Sits at the Interface of Stress and Anxiety

artículo científico publicado en 2016

Fibroblast growth factor 2 alters the oxytocin receptor in a developmental model of anxiety-like behavior in male rat pups

artículo científico publicado en 2016

Fibroblast growth factor 2 regulates activity and gene expression of human post-mitotic excitatory neurons.

artículo científico publicado en 2017

Fibroblast growth factor 9 is a novel modulator of negative affect

artículo científico publicado en 2015

Fibroblast growth factor-2 (FGF2) augmentation early in life alters hippocampal development and rescues the anxiety phenotype in vulnerable animals ⬇️

artículo científico publicado el 25 de abril de 2011

Fibroblast growth factor-2: an endogenous antidepressant and anxiolytic molecule?

artículo científico publicado en 2012

Fluorescent imaging of mitochondrial nitric oxide in living cells

artículo científico publicado en 2002

Frontal and limbic activation during inhibitory control predicts treatment response in major depressive disorder

artículo científico publicado en 2007

G protein-linked signaling pathways in bipolar and major depressive disorders

artículo científico publicado en 2013

Gender-specific disruptions in emotion processing in younger adults with depression

artículo científico publicado en 2009

Gender-specific gene expression in post-mortem human brain: localization to sex chromosomes

artículo científico publicado en 2004

Gene expression changes in the prefrontal cortex, anterior cingulate cortex and nucleus accumbens of mood disorders subjects that committed suicide

artículo científico publicado en 2012

Gene expression profiling of neurochemically defined regions of the human brain by in situ hybridization-guided laser capture microdissection

artículo científico publicado en 2008

Genetic Liability for Internalizing Versus Externalizing Behavior Manifests in the Developing and Adult Hippocampus: Insight From a Meta-analysis of Transcriptional Profiling Studies in a Selectively Bred Rat Model

artículo científico publicado en 2020

Genetic background and epigenetic modifications in the core of the nucleus accumbens predict addiction-like behavior in a rat model.

artículo científico publicado en 2016

Genetic relationship between five psychiatric disorders estimated from genome-wide SNPs

artículo científico publicado en 2013

Genome-wide association and meta-analysis of bipolar disorder in individuals of European ancestry

scientific journal article

Genome-wide association study identifies 30 loci associated with bipolar disorder.

artículo científico publicado en 2019

Genomic Dissection of Bipolar Disorder and Schizophrenia, Including 28 Subphenotypes

article

Glucocorticoid and mineralocorticoid receptor expression in the human hippocampus in major depressive disorder ⬇️

artículo científico publicado el 6 de diciembre de 2012

Glucocorticoid receptor overexpression in forebrain: a mouse model of increased emotional lability

scholarly article

Glucocorticoids and resilience

scientific article published on 24 November 2018

Glutamate transporters: A key piece in the glutamate puzzle of major depressive disorder ⬇️

artículo científico publicado el 24 de mayo de 2013

High novelty-seeking predicts aggression and gene expression differences within defined serotonergic cell groups ⬇️

artículo científico publicado el 22 de agosto de 2011

High novelty-seeking rats are resilient to negative physiological effects of the early life stress ⬇️

artículo científico publicado el 6 de noviembre de 2013

In memory of Elizabeth Young

artículo científico publicado en 2009

Inborn differences in environmental reactivity predict divergent diurnal behavioral, endocrine, and gene expression rhythms ⬇️

artículo científico publicado el 20 de julio de 2011

Individual Differences in Cue-Induced Motivation and Striatal Systems in Rats Susceptible to Diet-Induced Obesity

artículo científico publicado en 2015

Individual differences in novelty-seeking and emotional reactivity correlate with variation in maternal behavior

artículo científico publicado en 2007

Individual differences in the attribution of incentive salience to a reward-related cue: influence on cocaine sensitization

artículo científico publicado en 2007

Individual differences in the attribution of incentive salience to reward-related cues: Implications for addiction

artículo científico publicado en 2008

Individual differences in the improvement of cocaine-induced place preference response by the 5-HT2C receptor antagonist SB242084 in rats ⬇️

artículo científico publicado el 12 de octubre de 2011

Individual differences in the propensity to approach signals vs goals promote different adaptations in the dopamine system of rats

artículo científico publicado en 2006

Inference of cell type content from human brain transcriptomic datasets illuminates the effects of age, manner of death, dissection, and psychiatric diagnosis

artículo científico publicado en 2018

Interaction between alpha-melanocyte-stimulating hormone and corticotropin-releasing hormone in the regulation of feeding and hypothalamo-pituitary-adrenal responses.

artículo científico publicado en 2003

Introduction to Social Neuroscience: Gene, Environment, Brain, Body ⬇️

artículo científico publicado el 1 de agosto de 2011

Lack of association to a NRG1 missense polymorphism in schizophrenia or bipolar disorder in a Costa Rican population

artículo científico publicado en 2011

Lesions of the paraventricular nucleus of the thalamus differentially affect sign- and goal-tracking conditioned responses

artículo científico publicado en 2015

Male rats that differ in novelty exploration demonstrate distinct patterns of sexual behavior ⬇️

artículo científico publicado el 1 de febrero de 2013

Maternal Style Selectively Shapes Amygdalar Development and Social Behavior in Rats Genetically Prone to High Anxiety.

artículo científico publicado en 2015

Medicine. The future of psychiatric research: genomes and neural circuits

artículo científico publicado en 2010

Methodological considerations for gene expression profiling of human brain.

scientific article published on 08 April 2007

Microarray technology: a review of new strategies to discover candidate vulnerability genes in psychiatric disorders

artículo científico publicado en 2003

Mineralocorticoid receptor function in major depression

artículo científico publicado en 2003

Mineralocorticoid receptor overexpression in forebrain decreases anxiety-like behavior and alters the stress response in mice

artículo científico publicado en 2007

Mitochondrial Complex I Deficiency in Schizophrenia and Bipolar Disorder and Medication Influence.

artículo científico publicado en 2017

Mitochondrial involvement in psychiatric disorders

artículo científico publicado en 2008

Mitochondrial mutations in subjects with psychiatric disorders

artículo científico publicado en 2015

Mitochondrial variants in schizophrenia, bipolar disorder, and major depressive disorder

artículo científico publicado en 2009

Neonatal FGF2 alters cocaine self-administration in the adult rat

artículo científico publicado en 2008

Neonatal fibroblast growth factor treatment enhances cocaine sensitization ⬇️

artículo científico publicado el 1 de noviembre de 2012

Neural and environmental factors impacting maternal behavior differences in high- versus low-novelty-seeking rats

artículo científico publicado en 2010

Neural cell adhesion molecule peptide mimetics modulate emotionality: pharmacokinetic and behavioral studies in rats and non-human primates

artículo científico publicado en 2018

Neurobiological correlates of individual differences in novelty-seeking behavior in the rat: differential expression of stress-related molecules

artículo científico publicado en 2000

Neuroscience Training for the 21st Century

artículo científico publicado en 2016

Nociceptin/orphanin FQ and opioid receptor-like receptor mRNA expression in dopamine systems

artículo científico publicado en 2002

Novelty-seeking behavior predicts vulnerability in a rodent model of depression ⬇️

artículo científico publicado el 12 de febrero de 2011

Overexpressing the glucocorticoid receptor in forebrain causes an aging-like neuroendocrine phenotype and mild cognitive dysfunction

artículo científico publicado en 2007

Pattern of forebrain activation in high novelty-seeking rats following aggressive encounter ⬇️

artículo científico publicado el 19 de agosto de 2011

Persistent alterations in cognitive function and prefrontal dopamine D2 receptors following extended, but not limited, access to self-administered cocaine

artículo científico publicado en 2008

Pheromone-induced anorexia in male Syrian hamsters

artículo científico publicado en 2003

Physician-Training Stress and Accelerated Cellular Aging

artículo científico publicado en 2019

Post-mortem molecular profiling of three psychiatric disorders

artículo científico publicado en 2017

Post-mortem molecular profiling of three psychiatric disorders

Prenatal stress does not alter innate novelty-seeking behavioral traits, but differentially affects individual differences in neuroendocrine stress responsivity

artículo científico publicado en 2008

Previous experience affects subsequent anxiety-like responses in rats bred for novelty seeking.

artículo científico publicado en 2007

Protective effects of chronic mild stress during adolescence in the low-novelty responder rat.

artículo científico publicado en 2015

Quantitative Trait Locus and Brain Expression of HLA-DPA1 Offers Evidence of Shared Immune Alterations in Psychiatric Disorders

artículo científico publicado en 2016

Regulation of hippocampal alpha1d adrenergic receptor mRNA by corticosterone in adrenalectomized rats.

artículo científico publicado en 2008

Relationship of presympathetic-premotor neurons to the serotonergic transmitter system in the rat brainstem

artículo científico publicado en 2006

Revealing a latent variable: individual differences in affective response to repeated injections

artículo científico publicado en 2015

Revisiting the Stress Concept: Implications for Affective Disorders

artículo científico publicado en 2020

Risk-assessment and Coping Strategies Segregate with Divergent Intrinsic Aerobic Capacity in Rats ⬇️

artículo científico publicado el 6 de octubre de 2010

Rostral elements of sympatho-motor circuitry: a virally mediated transsynaptic tracing study.

artículo científico publicado en 2006

S100A8/A9 Drives Neuroinflammatory Priming and Protects against Anxiety-like Behavior after Sepsis.

artículo científico publicado en 2018

SAT-358 Corticosterone Treatment during Sepsis Results in a Primary Adrenal Defect in Male Survivors

artículo científico publicado en 2019

SNPs on Chips: The Hidden Genetic Code in Expression Arrays

scientific article published on 11 May 2006

Sample matching by inferred agonal stress in gene expression analyses of the brain

artículo científico publicado en 2007

Selective breeding for divergence in novelty-seeking traits: heritability and enrichment in spontaneous anxiety-related behaviors.

artículo científico publicado en 2006

Selective down-regulation of hippocampal glucocorticoid receptors during opiate withdrawal

artículo científico publicado en 2003

Selectively Bred Rats Provide a Unique Model of Vulnerability to PTSD-Like Behavior and Respond Differentially to FGF2 Augmentation Early in Life

artículo científico publicado en 2017

Sepsis survivor mice exhibit a behavioral endocrine syndrome with ventral hippocampal dysfunction

scientific article published on 13 April 2020

Serotonin 5-HT1A, 5-HT1B, and 5-HT2A receptor mRNA expression in subjects with major depression, bipolar disorder, and schizophrenia

artículo científico publicado en 2004

Short-Hairpin RNA Silencing of Endogenous Fibroblast Growth Factor 2 in Rat Hippocampus Increases Anxiety Behavior ⬇️

artículo científico publicado el 7 de enero de 2011

Socially-induced brain 'fertilization': play promotes brain derived neurotrophic factor transcription in the amygdala and dorsolateral frontal cortex in juvenile rats

artículo científico publicado en 2003

Splice-Break: exploiting an RNA-seq splice junction algorithm to discover mitochondrial DNA deletion breakpoints and analyses of psychiatric disorders.

artículo científico publicado en 2019

Spontaneous activity, economy of activity, and resistance to diet-induced obesity in rats bred for high intrinsic aerobic capacity

artículo científico publicado en 2010

Stress amplifies sex differences in primate prefrontal profiles of gene expression

artículo científico publicado en 2017

Stressed and depressed

artículo científico publicado en 2005

Syrian hamster proopiomelanocortin cDNA cloning and early seasonal changes in testicular expression

artículo científico publicado en 2003

Systematic changes in gene expression in postmortem human brains associated with tissue pH and terminal medical conditions

artículo científico publicado en 2004

The CCK-system mediates adaptation to novelty-induced stress in the rat: a pharmacological evidence.

artículo científico publicado en 2007

The CCK-system underpins novelty-seeking behavior in the rat: gene expression and pharmacological analyses.

artículo científico publicado en 2008

The ability of amphetamine to evoke arc (Arg 3.1) mRNA expression in the caudate, nucleus accumbens and neocortex is modulated by environmental context

artículo científico publicado en 2002

The critical importance of basic animal research for neuropsychiatric disorders

scientific article published on 02 May 2019

The effects of novelty-seeking phenotypes and sex differences on acquisition of cocaine self-administration in selectively bred High-Responder and Low-Responder rats

artículo científico publicado en 2008

The fibroblast growth factor family: neuromodulation of affective behavior

artículo científico publicado en 2012

The fibroblast growth factor system and mood disorders.

artículo científico publicado en 2006

The fibroblast growth factor system is downregulated following social defeat

artículo científico publicado en 2007

The in Vivo Neurochemical Profile of Selectively Bred High-Responder and Low-Responder Rats Reveals Baseline, Cocaine-Evoked, and Novelty-Evoked Differences in Monoaminergic Systems

artículo científico publicado en 2017

The microRNA network is altered in anterior cingulate cortex of patients with unipolar and bipolar depression

artículo científico publicado en 2016

The neuroscience information framework: a data and knowledge environment for neuroscience

artículo científico publicado en 2008

Tissue-Specific and Substrate-Specific Endoproteolytic Cleavage of Monkey Pro-Opiomelanocortin in Heterologous Endocrine Cells: Processing at Lys-Lys Dibasic Pairs

Transcriptional profiling of the developing rat brain reveals that the most dramatic regional differentiation in gene expression occurs postpartum.

artículo científico publicado en 2006

Treatment resistant depression: A multi-scale, systems biology approach

artículo científico publicado en 2017

Uneven balance of power between hypothalamic peptidergic neurons in the control of feeding

article published in the Proceedings of the National Academy of Sciences of the United States of America

Upregulation of GAD65 mRNA in the medulla of the rat model of metabolic syndrome

artículo científico publicado en 2007

Utilizing a unique animal model to better understand human temperament

artículo científico publicado en 2017

c-fos mRNA induction in acute and chronic audiogenic stress: possible role of the orbitofrontal cortex in habituation

artículo científico publicado en 2002

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