Lista de obras - Kwok Wai Lo - Dominio Público Uruguay

AMOTL1 enhances YAP1 stability and promotes YAP1-driven gastric oncogenesis

artículo científico publicado en 2020

Activation of sterol regulatory element-binding protein 1 (SREBP1)-mediated lipogenesis by the Epstein-Barr virus-encoded latent membrane protein 1 (LMP1) promotes cell proliferation and progression of nasopharyngeal carcinoma

artículo científico publicado en 2018

Alterations of RAS signalling in Chinese multiple myeloma patients: absent BRAF and rare RAS mutations, but frequent inactivation of RASSF1A by transcriptional silencing or expression of a non-functional variant transcript.

artículo científico publicado en 2003

Analysis of cell cycle regulators: p16INK4A, pRb, and CDK4 in low- and high-grade meningiomas

artículo científico publicado en 1998

Are special read alignment strategies necessary and cost-effective when handling sequencing reads from patient-derived tumor xenografts?

artículo científico publicado en 2014

BS69, a specific adaptor in the latent membrane protein 1-mediated c-Jun N-terminal kinase pathway

artículo científico publicado en 2006

CD24, CD44 and EpCAM enrich for tumour-initiating cells in a newly established patient-derived xenograft of nasopharyngeal carcinoma.

artículo científico publicado en 2017

CD44+ cancer stem-like cells in EBV-associated nasopharyngeal carcinoma.

artículo científico publicado en 2012

Cancer stem-like cells in Epstein-Barr virus-associated nasopharyngeal carcinoma

artículo científico

Characterization of a new EBV-associated nasopharyngeal carcinoma cell line.

artículo científico

Clinical implications of promoter hypermethylation in RASSF1A and MGMT in retinoblastoma

artículo científico publicado en 2005

Complete genomic sequence of Epstein-Barr virus in nasopharyngeal carcinoma cell line C666-1.

artículo científico publicado en 2013

Comprehensive characterization of the patient-derived xenograft and the paralleled primary hepatocellular carcinoma cell line

artículo científico publicado en 2016

Constitutive activation of distinct NF-κB signals in EBV-associated nasopharyngeal carcinoma.

artículo científico publicado en 2013

Copy number gain of granulin-epithelin precursor (GEP) at chromosome 17q21 associates with overexpression in human liver cancer.

artículo científico publicado en 2015

Deciphering the molecular genetic basis of NPC through molecular, cytogenetic, and epigenetic approaches

artículo científico publicado en 2012

Detection of recurrent chromosomal gains and losses in primary nasopharyngeal carcinoma by comparative genomic hybridisation

artículo científico publicado en 1999

Dysregulation of microRNA-204 mediates migration and invasion of endometrial cancer by regulating FOXC1.

artículo científico publicado en 2011

EBV-encoded miRNAs can sensitize nasopharyngeal carcinoma to chemotherapeutic drugs by targeting BRCA1

artículo científico publicado en 2020

EBV-encoded miRNAs target ATM-mediated response in nasopharyngeal carcinoma

artículo científico publicado en 2017

Enhanced IL-6/IL-6R Signaling Promotes Growth and Malignant Properties in EBV-Infected Premalignant and Cancerous Nasopharyngeal Epithelial Cells ⬇️

artículo científico publicado el 1 de enero de 2013

Epigenetic inactivation of inositol polyphosphate 4-phosphatase B (INPP4B), a regulator of PI3K/AKT signaling pathway in EBV-associated nasopharyngeal carcinoma

artículo científico publicado en 2014

Epigenetic inactivation of the deleted in lung and esophageal cancer 1 gene in nasopharyngeal carcinoma.

artículo científico publicado en 2007

Epstein-Barr Virus-Encoded Latent Membrane Protein 1 Upregulates Glucose Transporter 1 Transcription via the mTORC1/NF-κB Signaling Pathways

artículo científico publicado en 2017

Epstein-Barr virus infection and nasopharyngeal carcinoma

artículo científico publicado en 2017

Epstein-Barr virus infection and persistence in nasopharyngeal epithelial cells

artículo científico

Epstein-Barr virus infection in immortalized nasopharyngeal epithelial cells: regulation of infection and phenotypic characterization.

artículo científico publicado en 2010

Establishment and characterization of new tumor xenografts and cancer cell lines from EBV-positive nasopharyngeal carcinoma

artículo científico publicado en 2018

Etiological factors of nasopharyngeal carcinoma

artículo científico publicado en 2014

Exome and genome sequencing of nasopharynx cancer identifies NF-κB pathway activating mutations

artículo científico publicado en 2017

FGF18, a prominent player in FGF signaling, promotes gastric tumorigenesis through autocrine manner and is negatively regulated by miR-590-5p.

artículo científico publicado en 2018

FGF18-FGFR2 signaling triggers the activation of c-Jun-YAP1 axis to promote carcinogenesis in a subgroup of gastric cancer patients and indicates translational potential

scientific article published on 15 September 2020

Frequent c-myc and Int-2 overrepresentations in nasopharyngeal carcinoma

scientific article published on 01 February 2000

Generation of monoclonal antibodies against Hong Kong nasopharyngeal carcinoma-associated Epstein-Barr virus latent membrane protein 1 (LMP1).

artículo científico publicado en 2002

Genetic and epigenetic changes in nasopharyngeal carcinoma.

artículo científico publicado en 2002

Genomic Landscapes of EBV-Associated Nasopharyngeal Carcinoma vs. HPV-Associated Head and Neck Cancer

artículo científico publicado en 2018

Genomic profiles of nasopharyngeal carcinoma: The importance of histological subtyping and Epstein-Barr virus in situ assays.

artículo científico publicado en 2017

Hepatocyte growth factor enhances proteolysis and invasiveness of human nasopharyngeal cancer cells through activation of PI3K and JNK.

artículo científico publicado en 2008

High frequency of p16INK4A gene alterations in hepatocellular carcinoma

artículo científico publicado en 1999

Hypermethylation of the tumor suppressor gene RASSFIA and frequent concomitant loss of heterozygosity at 3p21 in cervical cancers.

artículo científico publicado en 2003

Identification of a novel 12p13.3 amplicon in nasopharyngeal carcinoma

scientific article published on 01 January 2010

Identification of a recurrent transforming UBR5-ZNF423 fusion gene in EBV-associated nasopharyngeal carcinoma.

artículo científico publicado en 2013

Identification of molecular markers and signaling pathway in endometrial cancer in Hong Kong Chinese women by genome-wide gene expression profiling.

artículo científico publicado en 2006

Inhibition of the LKB1-AMPK pathway by the Epstein-Barr virus-encoded LMP1 promotes proliferation and transformation of human nasopharyngeal epithelial cells

artículo científico publicado en 2013

Latent membrane protein 1 and macrophage‐derived <scp>TNFα</scp> synergistically activate and mobilize invadopodia to drive invasion of nasopharyngeal carcinoma

artículo científico publicado en 2023

Loss of heterozygosity and mutations are the major mechanisms of RB1 gene inactivation in Chinese with sporadic retinoblastoma.

artículo científico publicado en 2002

Loss of heterozygosity of chromosome 14q in low- and high-grade meningiomas

scientific article published on 01 July 1997

Loss of heterozygosity on the short arm of chromosome 3 in nasopharyngeal carcinoma

artículo científico publicado en 1991

Metachronous bilateral mammary metaplastic and infiltrating duct carcinomas: a molecular study for clonality

artículo científico publicado en 2002

Multicenter phase II study of the AKT inhibitor MK-2206 in recurrent or metastatic nasopharyngeal carcinoma from patients in the mayo phase II consortium and the cancer therapeutics research group (MC1079).

artículo científico

Nasopharyngeal carcinoma: genetic changes, Epstein-Barr virus infection, or both. A clinical and molecular study of 36 patients.

artículo científico publicado en 1993

Nuclear factor-Y and Epstein Barr virus in nasopharyngeal cancer

artículo científico publicado en 2008

Oncogenic S1P signalling in EBV-associated nasopharyngeal carcinoma activates AKT and promotes cell migration through S1P receptor 3.

artículo científico publicado en 2017

Overexpression of PIN1 Enhances Cancer Growth and Aggressiveness with Cyclin D1 Induction in EBV-Associated Nasopharyngeal Carcinoma

artículo científico publicado en 2016

Photodynamic therapy-mediated modulation of inflammatory cytokine production by Epstein-Barr virus-infected nasopharyngeal carcinoma cells.

artículo científico publicado en 2010

Preclinical evaluation of ribociclib and its synergistic effect in combination with alpelisib in non-keratinizing nasopharyngeal carcinoma.

artículo científico publicado en 2018

Progressive increase of genetic alteration in urinary bladder cancer by combined allelotyping analysis and comparative genomic hybridization

artículo científico publicado en 2009

Promoter hypermethylation of the EDNRB gene in nasopharyngeal carcinoma.

artículo científico publicado en 2002

Putative tumour-suppressor gene DAB2 is frequently down regulated by promoter hypermethylation in nasopharyngeal carcinoma

artículo científico publicado en 2010

RASAL2 promotes tumor progression through LATS2/YAP1 axis of hippo signaling pathway in colorectal cancer

scientific article published on 23 July 2018

Reactivation of Epstein-Barr virus by a dual-responsive fluorescent EBNA1-targeting agent with Zn2+-chelating function

scientific article published on 10 December 2019

Regulation of RASSF1A in nasopharyngeal cells and its response to UV irradiation.

artículo científico publicado en 2009

Silencing of the retinoid response gene TIG1 by promoter hypermethylation in nasopharyngeal carcinoma

artículo científico publicado en 2005

Somatostatin receptor 2 expression in nasopharyngeal cancer is induced by Epstein Barr virus infection: impact on prognosis, imaging and therapy

artículo científico publicado en 2021

Stable expression of EBERs in immortalized nasopharyngeal epithelial cells confers resistance to apoptotic stress.

artículo científico publicado en 2005

Ternary copper(II) complex: NCI60 screening, toxicity studies, and evaluation of efficacy in xenograft models of nasopharyngeal carcinoma

artículo científico publicado en 2018

The role of Epstein-Barr virus in epithelial malignancies

artículo científico

Two distinct regions of deletion on chromosome 13q in primary nasopharyngeal carcinoma

scientific article published on 01 October 1999

Yin Yang 1-mediated epigenetic silencing of tumour-suppressive microRNAs activates nuclear factor-κB in hepatocellular carcinoma.

artículo científico publicado en 2016

miR-31 is consistently inactivated in EBV-associated nasopharyngeal carcinoma and contributes to its tumorigenesis

artículo científico publicado en 2014

Lista de obras de Kwok Wai Lo

AMOTL1 enhances YAP1 stability and promotes YAP1-driven gastric oncogenesis

Activation of sterol regulatory element-binding protein 1 (SREBP1)-mediated lipogenesis by the Epstein-Barr virus-encoded latent membrane protein 1 (LMP1) promotes cell proliferation and progression of nasopharyngeal carcinoma

Alterations of RAS signalling in Chinese multiple myeloma patients: absent BRAF and rare RAS mutations, but frequent inactivation of RASSF1A by transcriptional silencing or expression of a non-functional variant transcript.

Analysis of cell cycle regulators: p16INK4A, pRb, and CDK4 in low- and high-grade meningiomas

Are special read alignment strategies necessary and cost-effective when handling sequencing reads from patient-derived tumor xenografts?

BS69, a specific adaptor in the latent membrane protein 1-mediated c-Jun N-terminal kinase pathway

CD24, CD44 and EpCAM enrich for tumour-initiating cells in a newly established patient-derived xenograft of nasopharyngeal carcinoma.

CD44+ cancer stem-like cells in EBV-associated nasopharyngeal carcinoma.

Cancer stem-like cells in Epstein-Barr virus-associated nasopharyngeal carcinoma

Characterization of a new EBV-associated nasopharyngeal carcinoma cell line.

Clinical implications of promoter hypermethylation in RASSF1A and MGMT in retinoblastoma

Complete genomic sequence of Epstein-Barr virus in nasopharyngeal carcinoma cell line C666-1.

Comprehensive characterization of the patient-derived xenograft and the paralleled primary hepatocellular carcinoma cell line

Constitutive activation of distinct NF-κB signals in EBV-associated nasopharyngeal carcinoma.

Copy number gain of granulin-epithelin precursor (GEP) at chromosome 17q21 associates with overexpression in human liver cancer.

Deciphering the molecular genetic basis of NPC through molecular, cytogenetic, and epigenetic approaches

Detection of recurrent chromosomal gains and losses in primary nasopharyngeal carcinoma by comparative genomic hybridisation

Dysregulation of microRNA-204 mediates migration and invasion of endometrial cancer by regulating FOXC1.

EBV-encoded miRNAs can sensitize nasopharyngeal carcinoma to chemotherapeutic drugs by targeting BRCA1

EBV-encoded miRNAs target ATM-mediated response in nasopharyngeal carcinoma

Enhanced IL-6/IL-6R Signaling Promotes Growth and Malignant Properties in EBV-Infected Premalignant and Cancerous Nasopharyngeal Epithelial Cells ⬇️

Epigenetic inactivation of inositol polyphosphate 4-phosphatase B (INPP4B), a regulator of PI3K/AKT signaling pathway in EBV-associated nasopharyngeal carcinoma

Epigenetic inactivation of the deleted in lung and esophageal cancer 1 gene in nasopharyngeal carcinoma.

Epstein-Barr Virus-Encoded Latent Membrane Protein 1 Upregulates Glucose Transporter 1 Transcription via the mTORC1/NF-κB Signaling Pathways

Epstein-Barr virus infection and nasopharyngeal carcinoma

Epstein-Barr virus infection and persistence in nasopharyngeal epithelial cells

Epstein-Barr virus infection in immortalized nasopharyngeal epithelial cells: regulation of infection and phenotypic characterization.

Establishment and characterization of new tumor xenografts and cancer cell lines from EBV-positive nasopharyngeal carcinoma

Etiological factors of nasopharyngeal carcinoma

Exome and genome sequencing of nasopharynx cancer identifies NF-κB pathway activating mutations

FGF18, a prominent player in FGF signaling, promotes gastric tumorigenesis through autocrine manner and is negatively regulated by miR-590-5p.

FGF18-FGFR2 signaling triggers the activation of c-Jun-YAP1 axis to promote carcinogenesis in a subgroup of gastric cancer patients and indicates translational potential

Frequent c-myc and Int-2 overrepresentations in nasopharyngeal carcinoma

Generation of monoclonal antibodies against Hong Kong nasopharyngeal carcinoma-associated Epstein-Barr virus latent membrane protein 1 (LMP1).

Genetic and epigenetic changes in nasopharyngeal carcinoma.

Genomic Landscapes of EBV-Associated Nasopharyngeal Carcinoma vs. HPV-Associated Head and Neck Cancer

Genomic profiles of nasopharyngeal carcinoma: The importance of histological subtyping and Epstein-Barr virus in situ assays.

Hepatocyte growth factor enhances proteolysis and invasiveness of human nasopharyngeal cancer cells through activation of PI3K and JNK.

High frequency of p16INK4A gene alterations in hepatocellular carcinoma

Hypermethylation of the tumor suppressor gene RASSFIA and frequent concomitant loss of heterozygosity at 3p21 in cervical cancers.

Identification of a novel 12p13.3 amplicon in nasopharyngeal carcinoma

Identification of a recurrent transforming UBR5-ZNF423 fusion gene in EBV-associated nasopharyngeal carcinoma.

Identification of molecular markers and signaling pathway in endometrial cancer in Hong Kong Chinese women by genome-wide gene expression profiling.

Inhibition of the LKB1-AMPK pathway by the Epstein-Barr virus-encoded LMP1 promotes proliferation and transformation of human nasopharyngeal epithelial cells

Latent membrane protein 1 and macrophage‐derived <scp>TNFα</scp> synergistically activate and mobilize invadopodia to drive invasion of nasopharyngeal carcinoma

Loss of heterozygosity and mutations are the major mechanisms of RB1 gene inactivation in Chinese with sporadic retinoblastoma.

Loss of heterozygosity of chromosome 14q in low- and high-grade meningiomas

Loss of heterozygosity on the short arm of chromosome 3 in nasopharyngeal carcinoma

Metachronous bilateral mammary metaplastic and infiltrating duct carcinomas: a molecular study for clonality

Multicenter phase II study of the AKT inhibitor MK-2206 in recurrent or metastatic nasopharyngeal carcinoma from patients in the mayo phase II consortium and the cancer therapeutics research group (MC1079).

Nasopharyngeal carcinoma: genetic changes, Epstein-Barr virus infection, or both. A clinical and molecular study of 36 patients.

Nuclear factor-Y and Epstein Barr virus in nasopharyngeal cancer

Oncogenic S1P signalling in EBV-associated nasopharyngeal carcinoma activates AKT and promotes cell migration through S1P receptor 3.

Overexpression of PIN1 Enhances Cancer Growth and Aggressiveness with Cyclin D1 Induction in EBV-Associated Nasopharyngeal Carcinoma

Photodynamic therapy-mediated modulation of inflammatory cytokine production by Epstein-Barr virus-infected nasopharyngeal carcinoma cells.

Preclinical evaluation of ribociclib and its synergistic effect in combination with alpelisib in non-keratinizing nasopharyngeal carcinoma.

Progressive increase of genetic alteration in urinary bladder cancer by combined allelotyping analysis and comparative genomic hybridization

Promoter hypermethylation of the EDNRB gene in nasopharyngeal carcinoma.

Putative tumour-suppressor gene DAB2 is frequently down regulated by promoter hypermethylation in nasopharyngeal carcinoma

RASAL2 promotes tumor progression through LATS2/YAP1 axis of hippo signaling pathway in colorectal cancer

Reactivation of Epstein-Barr virus by a dual-responsive fluorescent EBNA1-targeting agent with Zn2+-chelating function

Regulation of RASSF1A in nasopharyngeal cells and its response to UV irradiation.

Silencing of the retinoid response gene TIG1 by promoter hypermethylation in nasopharyngeal carcinoma

Somatostatin receptor 2 expression in nasopharyngeal cancer is induced by Epstein Barr virus infection: impact on prognosis, imaging and therapy

Stable expression of EBERs in immortalized nasopharyngeal epithelial cells confers resistance to apoptotic stress.

Ternary copper(II) complex: NCI60 screening, toxicity studies, and evaluation of efficacy in xenograft models of nasopharyngeal carcinoma

The role of Epstein-Barr virus in epithelial malignancies

Two distinct regions of deletion on chromosome 13q in primary nasopharyngeal carcinoma

Yin Yang 1-mediated epigenetic silencing of tumour-suppressive microRNAs activates nuclear factor-κB in hepatocellular carcinoma.

miR-31 is consistently inactivated in EBV-associated nasopharyngeal carcinoma and contributes to its tumorigenesis