Lista de obras - Julian Pardo - Dominio Público Uruguay

A Functional Analysis on the Interspecies Interaction between Mouse LFA-1 and Human Intercellular Adhesion Molecule-1 at the Cell Level

artículo científico publicado en 2017

A role of the mitochondrial apoptosis-inducing factor in granulysin-induced apoptosis.

artículo científico publicado en 2001

Acid sphingomyelinase is a key regulator of cytotoxic granule secretion by primary T lymphocytes

artículo científico publicado en 2009

Activated Allogeneic NK Cells Preferentially Kill Poor Prognosis B-Cell Chronic Lymphocytic Leukemia Cells.

artículo científico publicado en 2016

Activated human primary NK cells efficiently kill colorectal cancer cells in 3D spheroid cultures irrespectively of the level of PD-L1 expression.

artículo científico publicado en 2018

All-trans retinoic acid (ATRA) induces miR-23a expression, decreases CTSC expression and granzyme B activity leading to impaired NK cell cytotoxicity

artículo científico publicado en 2014

Antigen-specific primed cytotoxic T cells eliminate tumour cells in vivo and prevent tumour development, regardless of the presence of anti-apoptotic mutations conferring drug resistance.

artículo científico publicado en 2018

Antitumor immunotherapeutic and toxic properties of an HDL-conjugated chimeric IL-15 fusion protein.

artículo científico publicado en 2012

Attenuated Mycobacterium tuberculosis SO2 vaccine candidate is unable to induce cell death.

artículo científico publicado en 2012

Bim is a crucial regulator of apoptosis induced by Mycobacterium tuberculosis.

artículo científico publicado en 2014

Bis(methyl)gliotoxin proves to be a more stable and reliable marker for invasive aspergillosis than gliotoxin and suitable for use in diagnosis

artículo científico publicado en 2012

Blinking effect and the use of quantum dots in single molecule spectroscopy.

artículo científico publicado en 2012

CD56+/CD16- Natural Killer cells expressing the inflammatory protease granzyme A are enriched in synovial fluid from patients with osteoarthritis.

artículo científico publicado en 2017

Cell death induced by cytotoxic CD8+ T cells is immunogenic and primes caspase-3-dependent spread immunity against endogenous tumor antigens

scientific article published on 01 April 2020

Clinical validity of bis(methylthio)gliotoxin for the diagnosis of invasive aspergillosis

artículo científico publicado en 2015

Course of Infection with the Emergent Pathogen Brucella microti in Immunocompromised Mice ⬇️

artículo científico publicado el 8 de agosto de 2011

Development and characterization of a microfluidic model of the tumour microenvironment

artículo científico publicado en 2016

Dissecting the molecular mechanism of apoptosis during photothermal therapy using gold nanoprisms.

artículo científico publicado en 2014

Disseminated aspergillosis in an immunocompetent patient with detectable bis(methylthio)gliotoxin and negative galactomannan.

artículo científico publicado en 2016

Down-regulation of normal human T cell blast activation: roles of APO2L/TRAIL, FasL, and c- FLIP, Bim, or Bcl-x isoform expression.

artículo científico publicado en 2005

EMBO workshop on cytotoxicity, cell death and the immune system

artículo científico publicado en 2009

ESX-1-induced apoptosis during mycobacterial infection: to be or not to be, that is the question

artículo científico publicado en 2013

ESX-1-induced apoptosis is involved in cell-to-cell spread of Mycobacterium tuberculosis

artículo científico publicado en 2013

Effect of Surface Chemistry and Associated Protein Corona on the Long-Term Biodegradation of Iron Oxide Nanoparticles In Vivo.

artículo científico publicado en 2018

Elucidating sources and roles of granzymes A and B during bacterial infection and sepsis

artículo científico publicado en 2014

Essential complicity of perforin-granzyme and FAS-L mechanisms to achieve tumor rejection following treatment with anti-CD137 mAb

artículo científico publicado en 2013

Expansion of allogeneic NK cells with efficient antibody-dependent cell cytotoxicity against multiple tumors

scientific article published on 14 June 2018

FRET based quantification and screening technology platform for the interactions of leukocyte function-associated antigen-1 (LFA-1) with intercellular adhesion molecule-1 (ICAM-1).

artículo científico publicado en 2014

Granulysin induces apoptotic cell death and cleavage of the autophagy regulator Atg5 in human hematological tumors.

artículo científico publicado en 2013

Granzyme A Contributes to Inflammatory Arthritis in Mice Through Stimulation of Osteoclastogenesis.

artículo científico publicado en 2016

Granzyme A Is Expressed in Mouse Lungs during Mycobacterium tuberculosis Infection but Does Not Contribute to Protection In Vivo

artículo científico publicado en 2016

Granzyme A Is Required for Regulatory T-Cell Mediated Prevention of Gastrointestinal Graft-versus-Host Disease

artículo científico publicado en 2015

Granzyme B is expressed in mouse mast cells in vivo and in vitro and causes delayed cell death independent of perforin.

artículo científico publicado en 2007

Granzyme B of cytotoxic T cells induces extramitochondrial reactive oxygen species production via caspase-dependent NADPH oxidase activation.

artículo científico publicado en 2010

Granzyme B-induced and caspase 3-dependent cleavage of gelsolin by mouse cytotoxic T cells modifies cytoskeleton dynamics.

artículo científico publicado en 2010

Herpesvirus saimiri-transformed CD8+ T cells as a tool to study Chediak-Higashi syndrome cytolytic lymphocytes.

artículo científico publicado en 2005

How Do Cytotoxic Lymphocytes Kill Cancer Cells?

artículo científico publicado en 2015

Human CD8+ T cell blasts are more sensitive than CD4+ T cell blasts to regulation by APO2L/TRAIL

artículo científico publicado en 2005

Human NK cells activated by EBV(+) lymphoblastoid cells overcome anti-apoptotic mechanisms of drug resistance in haematological cancer cells.

artículo científico publicado en 2015

Human and mouse granzyme A induce a proinflammatory cytokine response.

artículo científico publicado en 2008

Immunoproteomic identification and characterization of Ni2+-regulated proteins implicates Ni2+ in the induction of monocyte cell death.

artículo científico publicado en 2017

In memoriam: Prof Christopher J Froelich (1951-2015)

artículo científico publicado en 2016

In vitro fungicidal photodynamic effect of hypericin on Trichophyton spp

artículo científico publicado en 2014

Inhibition of autophagy with chloroquine potentiates carfilzomib-induced apoptosis in myeloma cells in vitro and in vivo

artículo científico publicado en 2016

Intestinal Serotonin Transporter Inhibition by Toll-Like Receptor 2 Activation. A Feedback Modulation

artículo científico publicado en 2016

Lung metastases share common immune features regardless of primary tumor origin

artículo científico publicado en 2020

MAGUKs, scaffolding proteins at cell junctions, are substrates of different proteases during apoptosis

artículo científico publicado en 2011

MHC-I modulation due to changes in tumor cell metabolism regulates tumor sensitivity to CTL and NK cells

artículo científico publicado en 2015

Marine Mammal Brucella Reference Strains Are Attenuated in a BALB/c Mouse Model.

artículo científico publicado en 2016

Mouse cytotoxic T cell-derived granzyme B activates the mitochondrial cell death pathway in a Bim-dependent fashion

artículo científico publicado en 2015

Mouse granzyme K has pro-inflammatory potential.

artículo científico publicado en 2011

Multiparametric analysis of anti-proliferative and apoptotic effects of gold nanoprisms on mouse and human primary and transformed cells, biodistribution and toxicity in vivo.

artículo científico publicado en 2017

Oxidative phosphorylation induces de novo expression of the MHC class I in tumor cells through the ERK5 pathway.

artículo científico publicado en 2010

Perforin oligomers form arcs in cellular membranes: a locus for intracellular delivery of granzymes.

artículo científico publicado en 2014

Perforin rapidly induces plasma membrane phospholipid flip-flop

artículo científico publicado en 2011

Production of the Invasive Aspergillosis Biomarker Bis(methylthio)gliotoxin Within the Genus Aspergillus: In Vitro and in Vivo Metabolite Quantification and Genomic Analysis.

artículo científico publicado en 2018

Protein kinase C-theta is required for NK cell activation and in vivo control of tumor progression.

artículo científico publicado en 2009

Protein oligomerization mediated by the transmembrane carboxyl terminal domain of Bcl-XL

artículo científico publicado en 2011

Role of laeA in the Regulation of alb1, gliP, Conidial Morphology, and Virulence in Aspergillus fumigatus.

artículo científico publicado en 2007

Second meeting of the Spanish Immunotherapy Group GEIT (Grupo Español de Inmunoterapia), January 16, 2015, in Zaragoza, Spain

artículo científico publicado en 2015

Secretory lysosomes of mouse mast cells store and exocytose active caspase-3 in a strictly granzyme B dependent manner

artículo científico publicado en 2013

Serine protease inhibition attenuates rIL-12-induced GZMA activity and proinflammatory events by modulating the Th2 profile from estrogen-treated mice.

artículo científico publicado en 2014

The Untold Story of Granzymes in Oncoimmunology: Novel Opportunities with Old Acquaintances.

artículo científico publicado en 2017

The effect of acidic pH on the inhibitory efficacy of peptides against the interaction ICAM-1/LFA-1 studied by surface plasmon resonance (SPR).

artículo científico publicado en 2014

The mitochondrial protein Bak is pivotal for gliotoxin-induced apoptosis and a critical host factor of Aspergillus fumigatus virulence in mice

scientific journal article

The new strains Brucella inopinata BO1 and Brucella species 83-210 behave biologically like classic infectious Brucella species and cause death in murine models of infection.

artículo científico publicado en 2014

Toll-Like Receptors 2 and 4 Cooperate in the Control of the Emerging Pathogen Brucella microti

artículo científico publicado en 2016

Toll-like receptors 2 and 4 exert opposite effects on the contractile response induced by serotonin in mouse colon: role of serotonin receptors.

artículo científico publicado en 2016

Toll-like receptors 2 and 4 modulate intestinal IL-10 differently in ileum and colon.

artículo científico publicado en 2017

Toll-like receptors 2 and 4 modulate the contractile response induced by serotonin in mouse ileum: analysis of the serotonin receptors involved.

artículo científico publicado en 2015

Two death pathways induced by sorafenib in myeloma cells: Puma-mediated apoptosis and necroptosis.

artículo científico publicado en 2014

Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition)

artículo científico publicado en 2016

Lista de obras de Julian Pardo

A Functional Analysis on the Interspecies Interaction between Mouse LFA-1 and Human Intercellular Adhesion Molecule-1 at the Cell Level

A role of the mitochondrial apoptosis-inducing factor in granulysin-induced apoptosis.

Acid sphingomyelinase is a key regulator of cytotoxic granule secretion by primary T lymphocytes

Activated Allogeneic NK Cells Preferentially Kill Poor Prognosis B-Cell Chronic Lymphocytic Leukemia Cells.

Activated human primary NK cells efficiently kill colorectal cancer cells in 3D spheroid cultures irrespectively of the level of PD-L1 expression.

All-trans retinoic acid (ATRA) induces miR-23a expression, decreases CTSC expression and granzyme B activity leading to impaired NK cell cytotoxicity

Antigen-specific primed cytotoxic T cells eliminate tumour cells in vivo and prevent tumour development, regardless of the presence of anti-apoptotic mutations conferring drug resistance.

Antitumor immunotherapeutic and toxic properties of an HDL-conjugated chimeric IL-15 fusion protein.

Attenuated Mycobacterium tuberculosis SO2 vaccine candidate is unable to induce cell death.

Bim is a crucial regulator of apoptosis induced by Mycobacterium tuberculosis.

Bis(methyl)gliotoxin proves to be a more stable and reliable marker for invasive aspergillosis than gliotoxin and suitable for use in diagnosis

Blinking effect and the use of quantum dots in single molecule spectroscopy.

CD56+/CD16- Natural Killer cells expressing the inflammatory protease granzyme A are enriched in synovial fluid from patients with osteoarthritis.

Cell death induced by cytotoxic CD8+ T cells is immunogenic and primes caspase-3-dependent spread immunity against endogenous tumor antigens

Clinical validity of bis(methylthio)gliotoxin for the diagnosis of invasive aspergillosis

Course of Infection with the Emergent Pathogen Brucella microti in Immunocompromised Mice ⬇️

Development and characterization of a microfluidic model of the tumour microenvironment

Dissecting the molecular mechanism of apoptosis during photothermal therapy using gold nanoprisms.

Disseminated aspergillosis in an immunocompetent patient with detectable bis(methylthio)gliotoxin and negative galactomannan.

Down-regulation of normal human T cell blast activation: roles of APO2L/TRAIL, FasL, and c- FLIP, Bim, or Bcl-x isoform expression.

EMBO workshop on cytotoxicity, cell death and the immune system

ESX-1-induced apoptosis during mycobacterial infection: to be or not to be, that is the question

ESX-1-induced apoptosis is involved in cell-to-cell spread of Mycobacterium tuberculosis

Effect of Surface Chemistry and Associated Protein Corona on the Long-Term Biodegradation of Iron Oxide Nanoparticles In Vivo.

Elucidating sources and roles of granzymes A and B during bacterial infection and sepsis

Essential complicity of perforin-granzyme and FAS-L mechanisms to achieve tumor rejection following treatment with anti-CD137 mAb

Expansion of allogeneic NK cells with efficient antibody-dependent cell cytotoxicity against multiple tumors

FRET based quantification and screening technology platform for the interactions of leukocyte function-associated antigen-1 (LFA-1) with intercellular adhesion molecule-1 (ICAM-1).

Granulysin induces apoptotic cell death and cleavage of the autophagy regulator Atg5 in human hematological tumors.

Granzyme A Contributes to Inflammatory Arthritis in Mice Through Stimulation of Osteoclastogenesis.

Granzyme A Is Expressed in Mouse Lungs during Mycobacterium tuberculosis Infection but Does Not Contribute to Protection In Vivo

Granzyme A Is Required for Regulatory T-Cell Mediated Prevention of Gastrointestinal Graft-versus-Host Disease

Granzyme B is expressed in mouse mast cells in vivo and in vitro and causes delayed cell death independent of perforin.

Granzyme B of cytotoxic T cells induces extramitochondrial reactive oxygen species production via caspase-dependent NADPH oxidase activation.

Granzyme B-induced and caspase 3-dependent cleavage of gelsolin by mouse cytotoxic T cells modifies cytoskeleton dynamics.

Herpesvirus saimiri-transformed CD8+ T cells as a tool to study Chediak-Higashi syndrome cytolytic lymphocytes.

How Do Cytotoxic Lymphocytes Kill Cancer Cells?

Human CD8+ T cell blasts are more sensitive than CD4+ T cell blasts to regulation by APO2L/TRAIL

Human NK cells activated by EBV(+) lymphoblastoid cells overcome anti-apoptotic mechanisms of drug resistance in haematological cancer cells.

Human and mouse granzyme A induce a proinflammatory cytokine response.

Immunoproteomic identification and characterization of Ni2+-regulated proteins implicates Ni2+ in the induction of monocyte cell death.

In memoriam: Prof Christopher J Froelich (1951-2015)

In vitro fungicidal photodynamic effect of hypericin on Trichophyton spp

Inhibition of autophagy with chloroquine potentiates carfilzomib-induced apoptosis in myeloma cells in vitro and in vivo

Intestinal Serotonin Transporter Inhibition by Toll-Like Receptor 2 Activation. A Feedback Modulation

Lung metastases share common immune features regardless of primary tumor origin

MAGUKs, scaffolding proteins at cell junctions, are substrates of different proteases during apoptosis

MHC-I modulation due to changes in tumor cell metabolism regulates tumor sensitivity to CTL and NK cells

Marine Mammal Brucella Reference Strains Are Attenuated in a BALB/c Mouse Model.

Mouse cytotoxic T cell-derived granzyme B activates the mitochondrial cell death pathway in a Bim-dependent fashion

Mouse granzyme K has pro-inflammatory potential.

Multiparametric analysis of anti-proliferative and apoptotic effects of gold nanoprisms on mouse and human primary and transformed cells, biodistribution and toxicity in vivo.

Oxidative phosphorylation induces de novo expression of the MHC class I in tumor cells through the ERK5 pathway.

Perforin oligomers form arcs in cellular membranes: a locus for intracellular delivery of granzymes.

Perforin rapidly induces plasma membrane phospholipid flip-flop

Production of the Invasive Aspergillosis Biomarker Bis(methylthio)gliotoxin Within the Genus Aspergillus: In Vitro and in Vivo Metabolite Quantification and Genomic Analysis.

Protein kinase C-theta is required for NK cell activation and in vivo control of tumor progression.

Protein oligomerization mediated by the transmembrane carboxyl terminal domain of Bcl-XL

Role of laeA in the Regulation of alb1, gliP, Conidial Morphology, and Virulence in Aspergillus fumigatus.

Second meeting of the Spanish Immunotherapy Group GEIT (Grupo Español de Inmunoterapia), January 16, 2015, in Zaragoza, Spain

Secretory lysosomes of mouse mast cells store and exocytose active caspase-3 in a strictly granzyme B dependent manner

Serine protease inhibition attenuates rIL-12-induced GZMA activity and proinflammatory events by modulating the Th2 profile from estrogen-treated mice.

The Untold Story of Granzymes in Oncoimmunology: Novel Opportunities with Old Acquaintances.

The effect of acidic pH on the inhibitory efficacy of peptides against the interaction ICAM-1/LFA-1 studied by surface plasmon resonance (SPR).

The mitochondrial protein Bak is pivotal for gliotoxin-induced apoptosis and a critical host factor of Aspergillus fumigatus virulence in mice

The new strains Brucella inopinata BO1 and Brucella species 83-210 behave biologically like classic infectious Brucella species and cause death in murine models of infection.

Toll-Like Receptors 2 and 4 Cooperate in the Control of the Emerging Pathogen Brucella microti

Toll-like receptors 2 and 4 exert opposite effects on the contractile response induced by serotonin in mouse colon: role of serotonin receptors.

Toll-like receptors 2 and 4 modulate intestinal IL-10 differently in ileum and colon.

Toll-like receptors 2 and 4 modulate the contractile response induced by serotonin in mouse ileum: analysis of the serotonin receptors involved.

Two death pathways induced by sorafenib in myeloma cells: Puma-mediated apoptosis and necroptosis.

Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition)