Lista de obras - Antonella Naldini - Dominio Público Uruguay

2-Hydroxypropyl-β-cyclodextrin strongly improves water solubility and anti-proliferative activity of pyrazolo[3,4-d]pyrimidines Src-Abl dual inhibitors.

artículo científico publicado en 2010

A ribonuclease protection assay-based approach for analysis of angiogenic gene expression in archival tissues.

artículo científico

Analysis of protease-activated receptor-1 and -2 in human scar formation.

artículo científico publicado en 2007

Design, synthesis, biological activity, and ADME properties of pyrazolo[3,4-d]pyrimidines active in hypoxic human leukemia cells: a lead optimization study.

artículo científico publicado en 2011

Early response to bleomycin is characterized by different cytokine and cytokine receptor profiles in lungs.

artículo científico publicado en 2004

Expression of protease-activated receptors 1 and 2 in melanocytic nevi and malignant melanoma

artículo científico publicado en 2005

Human alpha-thrombin stimulates proliferation of interferon-gamma differentiated, growth-arrested U937 cells, overcoming differentiation-related changes in expression of p21CIP1/WAF1 and cyclin D1

scientific article published on 01 June 2002

Hydroxylase Inhibition Selectively Induces Cell Death in Monocytes

artículo científico publicado en 2019

Hypoxia affects dendritic cell survival: role of the hypoxia-inducible factor-1α and lipopolysaccharide.

artículo científico publicado en 2012

Hypoxia influences the cellular cross-talk of human dermal fibroblasts. A proteomic approach

artículo científico publicado en 2007

Identification of a functional role for the protease-activated receptor-1 in hypoxic breast cancer cells

artículo científico publicado en 2008

Identification of thrombin-like activity in ovarian cancer associated ascites and modulation of multiple cytokine networks

artículo científico publicado en 2011

In vitro cytokine production and T-cell proliferation in patients undergoing cardiopulmonary by-pass

artículo científico publicado en 1995

Inducible nitric oxide synthase activity correlates with lymphangiogenesis and vascular endothelial growth factor-C expression in head and neck squamous cell carcinoma.

artículo científico publicado en 2006

Inhibition of Bcr-Abl phosphorylation and induction of apoptosis by pyrazolo[3,4-d]pyrimidines in human leukemia cells

artículo científico publicado en 2007

Inhibition of smoothened in breast cancer cells reduces CAXII expression and cell migration

scientific article published on 21 August 2018

Interleukin 10 production in patients undergoing cardiopulmonary bypass: evidence of inhibition of Th-1-type responses

artículo científico publicado en 1999

Interleukin-1β regulates the migratory potential of MDAMB231 breast cancer cells through the hypoxia-inducible factor-1α.

artículo científico publicado en 2010

N-[2-Methyl-5-(triazol-1-yl)phenyl]pyrimidin-2-amine as a scaffold for the synthesis of inhibitors of Bcr-Abl.

artículo científico publicado en 2011

New pyrazolo[3,4-d]pyrimidines endowed with A431 antiproliferative activity and inhibitory properties of Src phosphorylation.

artículo científico publicado en 2004

Plasma levels of immunosuppressive mediators during cardiopulmonary bypass.

artículo científico publicado en 1996

Protease-activated receptor 1-selective antagonist SCH79797 inhibits cell proliferation and induces apoptosis by a protease-activated receptor 1-independent mechanism

artículo científico publicado en 2007

Protease-activated receptor-1 (PAR-1) promotes the motility of human melanomas and is associated to their metastatic phenotype

artículo científico publicado en 2009

Protease-activated receptor-2 downregulation is associated to vitiligo lesions

artículo científico publicado en 2009

Pyrazolo[3,4-d]pyrimidines as potent antiproliferative and proapoptotic agents toward A431 and 8701-BC cells in culture via inhibition of c-Src phosphorylation.

artículo científico publicado en 2006

Pyrazolo[3,4-d]pyrimidines endowed with antiproliferative activity on ductal infiltrating carcinoma cells.

artículo científico publicado en 2004

Regulation of angiogenesis by Th1- and Th2-type cytokines.

artículo científico publicado en 2003

Role of inflammatory mediators in angiogenesis.

artículo científico publicado en 2005

Role of the hypoxic microenvironment in the antitumor activity of tyrosine kinase inhibitors.

artículo científico publicado en 2011

Short-term hypoxia enhances the migratory capability of dendritic cell through HIF-1α and PI3K/Akt pathway

artículo científico publicado en 2014

Structure-based optimization of pyrazolo[3,4-d]pyrimidines as Abl inhibitors and antiproliferative agents toward human leukemia cell lines.

artículo científico publicado en 2008

Studies on tumor necrosis factor (TNF)—I. Pharmacokinetics of human recombinant TNF in rabbits and monkeys after intravenous administration

artículo científico publicado en 1987

The Shc protein RAI promotes an adaptive cell survival program in hypoxic neuroblastoma cells.

artículo científico publicado en 2017

The Shc protein Rai enhances T-cell survival under hypoxia

scientific article published on 15 January 2020

The adaptor protein p66Shc is a positive regulator in the angiogenic response induced by hypoxic T cells

artículo científico publicado en 2009

The effects of autologous platelet gel on inflammatory cytokine response in human peripheral blood mononuclear cells

artículo científico publicado en 2008

The lymphatic route. 1) Albumin and hyaluronidase modify the normal distribution of interferon in lymph and plasma

artículo científico publicado en 1986

The lymphatic route. VIII. Distribution and plasma clearance of recombinant human interleukin-2 after SC administration with albumin in patients

artículo científico publicado en 1993

The lymphatic route—II. Pharmacokinetics of human recombinant interferon-α2 injected with albumin as a retarder in rabbits

scientific article published on 01 January 1986

The lymphatic route—III. Pharmacokinetics of human natural interferon-β injected with albumin as a retarder in rabbits

artículo científico publicado en 1986

The thrombin peptide, TP508, enhances cytokine release and activates signaling events

artículo científico publicado en 2004

Thrombin Enhances T Cell Proliferative Responses and Cytokine Production

article

Thrombin Inhibits IFN-γ Production in Human Peripheral Blood Mononuclear Cells by Promoting a Th2 Profile

artículo científico publicado en 2006

Thrombin enhancement of interleukin-1 expression in mononuclear cells: involvement of proteinase-activated receptor-1

scientific article published on 01 December 2002

Thrombin receptor expression and responsiveness of human monocytic cells to thrombin is linked to interferon-induced cellular differentiation

artículo científico publicado en 1998

Thrombin regulates the expression of proangiogenic cytokines via proteolytic activation of protease-activated receptor-1

scientific article published on 01 November 2000

p66SHC promotes apoptosis and antagonizes mitogenic signaling in T cells.

artículo científico publicado en 2004

p66Shc is involved in promoting HIF-1alpha accumulation and cell death in hypoxic T cells

artículo científico publicado en 2007

Lista de obras de Antonella Naldini

2-Hydroxypropyl-β-cyclodextrin strongly improves water solubility and anti-proliferative activity of pyrazolo[3,4-d]pyrimidines Src-Abl dual inhibitors.

A ribonuclease protection assay-based approach for analysis of angiogenic gene expression in archival tissues.

Analysis of protease-activated receptor-1 and -2 in human scar formation.

Design, synthesis, biological activity, and ADME properties of pyrazolo[3,4-d]pyrimidines active in hypoxic human leukemia cells: a lead optimization study.

Early response to bleomycin is characterized by different cytokine and cytokine receptor profiles in lungs.

Expression of protease-activated receptors 1 and 2 in melanocytic nevi and malignant melanoma

Human alpha-thrombin stimulates proliferation of interferon-gamma differentiated, growth-arrested U937 cells, overcoming differentiation-related changes in expression of p21CIP1/WAF1 and cyclin D1

Hydroxylase Inhibition Selectively Induces Cell Death in Monocytes

Hypoxia affects dendritic cell survival: role of the hypoxia-inducible factor-1α and lipopolysaccharide.

Hypoxia influences the cellular cross-talk of human dermal fibroblasts. A proteomic approach

Identification of a functional role for the protease-activated receptor-1 in hypoxic breast cancer cells

Identification of thrombin-like activity in ovarian cancer associated ascites and modulation of multiple cytokine networks

In vitro cytokine production and T-cell proliferation in patients undergoing cardiopulmonary by-pass

Inducible nitric oxide synthase activity correlates with lymphangiogenesis and vascular endothelial growth factor-C expression in head and neck squamous cell carcinoma.

Inhibition of Bcr-Abl phosphorylation and induction of apoptosis by pyrazolo[3,4-d]pyrimidines in human leukemia cells

Inhibition of smoothened in breast cancer cells reduces CAXII expression and cell migration

Interleukin 10 production in patients undergoing cardiopulmonary bypass: evidence of inhibition of Th-1-type responses

Interleukin-1β regulates the migratory potential of MDAMB231 breast cancer cells through the hypoxia-inducible factor-1α.

N-[2-Methyl-5-(triazol-1-yl)phenyl]pyrimidin-2-amine as a scaffold for the synthesis of inhibitors of Bcr-Abl.

New pyrazolo[3,4-d]pyrimidines endowed with A431 antiproliferative activity and inhibitory properties of Src phosphorylation.

Plasma levels of immunosuppressive mediators during cardiopulmonary bypass.

Protease-activated receptor 1-selective antagonist SCH79797 inhibits cell proliferation and induces apoptosis by a protease-activated receptor 1-independent mechanism

Protease-activated receptor-1 (PAR-1) promotes the motility of human melanomas and is associated to their metastatic phenotype

Protease-activated receptor-2 downregulation is associated to vitiligo lesions

Pyrazolo[3,4-d]pyrimidines as potent antiproliferative and proapoptotic agents toward A431 and 8701-BC cells in culture via inhibition of c-Src phosphorylation.

Pyrazolo[3,4-d]pyrimidines endowed with antiproliferative activity on ductal infiltrating carcinoma cells.

Regulation of angiogenesis by Th1- and Th2-type cytokines.

Role of inflammatory mediators in angiogenesis.

Role of the hypoxic microenvironment in the antitumor activity of tyrosine kinase inhibitors.

Short-term hypoxia enhances the migratory capability of dendritic cell through HIF-1α and PI3K/Akt pathway

Structure-based optimization of pyrazolo[3,4-d]pyrimidines as Abl inhibitors and antiproliferative agents toward human leukemia cell lines.

Studies on tumor necrosis factor (TNF)—I. Pharmacokinetics of human recombinant TNF in rabbits and monkeys after intravenous administration

The Shc protein RAI promotes an adaptive cell survival program in hypoxic neuroblastoma cells.

The Shc protein Rai enhances T-cell survival under hypoxia

The adaptor protein p66Shc is a positive regulator in the angiogenic response induced by hypoxic T cells

The effects of autologous platelet gel on inflammatory cytokine response in human peripheral blood mononuclear cells

The lymphatic route. 1) Albumin and hyaluronidase modify the normal distribution of interferon in lymph and plasma

The lymphatic route. VIII. Distribution and plasma clearance of recombinant human interleukin-2 after SC administration with albumin in patients

The lymphatic route—II. Pharmacokinetics of human recombinant interferon-α2 injected with albumin as a retarder in rabbits

The lymphatic route—III. Pharmacokinetics of human natural interferon-β injected with albumin as a retarder in rabbits

The thrombin peptide, TP508, enhances cytokine release and activates signaling events

Thrombin Enhances T Cell Proliferative Responses and Cytokine Production

Thrombin Inhibits IFN-γ Production in Human Peripheral Blood Mononuclear Cells by Promoting a Th2 Profile

Thrombin enhancement of interleukin-1 expression in mononuclear cells: involvement of proteinase-activated receptor-1

Thrombin receptor expression and responsiveness of human monocytic cells to thrombin is linked to interferon-induced cellular differentiation

Thrombin regulates the expression of proangiogenic cytokines via proteolytic activation of protease-activated receptor-1

p66SHC promotes apoptosis and antagonizes mitogenic signaling in T cells.

p66Shc is involved in promoting HIF-1alpha accumulation and cell death in hypoxic T cells