Lista de obras - Pascale Moreau - Dominio Público Uruguay

A Kinase Inhibitor with Anti-Pim Kinase Activity is a Potent and Selective Cytotoxic Agent Toward Acute Myeloid Leukemia

artículo científico publicado en 2019

Analogues of antifungal tjipanazoles from rebeccamycin.

artículo científico publicado en 2004

Biological evaluation of glycosyl-isoindigo derivatives against the pathogenic agents of tropical diseases (malaria, Chagas disease, leishmaniasis and human African trypanosomiasis).

artículo científico publicado en 2011

Discovery of pyrido[3,4-g]quinazoline derivatives as CMGC family protein kinase inhibitors: Design, synthesis, inhibitory potency and X-ray co-crystal structure

artículo científico publicado en 2016

Heteroaromatic Pim Kinase Inhibitors Containing a Pyrazole Moiety.

artículo científico publicado en 2016

Identification of pyrrolo[2,3-g]indazoles as new Pim kinase inhibitors.

artículo científico publicado en 2013

In-vitro antiproliferative activities and kinase inhibitory potencies of glycosyl-isoindigo derivatives.

artículo científico publicado en 2007

Kaposi's sarcoma herpesvirus lytic replication compromises apoptotic response to p53 reactivation in virus-induced lymphomas.

artículo científico publicado en 2012

Kinase inhibitory potencies and in vitro antiproliferative activities of N-10 substituted pyrrolo[2,3-a]carbazole derivatives.

artículo científico publicado en 2012

New N-1,N-10-bridged pyrrolo[2,3-a]carbazole-3-carbaldehydes: synthesis and biological activities

artículo científico publicado en 2014

New pyrido[3,4-g]quinazoline derivatives as CLK1 and DYRK1A inhibitors: synthesis, biological evaluation and binding mode analysis

artículo científico publicado en 2019

Pim Kinases Promote Migration and Metastatic Growth of Prostate Cancer Xenografts

artículo científico publicado en 2015

Rebeccamycin analogues bearing amine substituents or other groups on the sugar moiety

artículo científico publicado en 2003

Rebeccamycin derivatives as dual DNA-damaging agents and potent checkpoint kinase 1 inhibitors.

artículo científico publicado en 2008

Semi-synthesis, topoisomerase I and kinases inhibitory properties, and antiproliferative activities of new rebeccamycin derivatives.

artículo científico publicado en 2003

Syntheses and biological activities (topoisomerase inhibition and antitumor and antimicrobial properties) of rebeccamycin analogues bearing modified sugar moieties and substituted on the imide nitrogen with a methyl group.

artículo científico publicado en 1997

Syntheses and biological activities of rebeccamycin analogues. Introduction of a halogenoacetyl substituent

artículo científico publicado en 1999

Synthesis and activities of new indolopyrrolobenzodiazepine derivatives toward acute myeloid leukemia cells

artículo científico publicado en 2015

Synthesis and antiproliferative activities of diversely substituted glycosyl-isoindigo derivatives.

artículo científico publicado en 2005

Synthesis and antiproliferative activities of indolin-2-one derivatives bearing amino acid moieties

artículo científico publicado en 2006

Synthesis and antiproliferative activities of isoindigo and azaisoindigo derivatives.

artículo científico publicado en 2007

Synthesis and biological activities of 4-substituted pyrrolo[2,3-a]carbazole Pim kinase inhibitors.

artículo científico publicado en 2012

Synthesis and biological activities of aminopyrimidyl-indoles structurally related to meridianins.

artículo científico publicado en 2009

Synthesis and biological activities of new di- and trimeric quinoline derivatives.

artículo científico publicado en 2010

Synthesis and biological activities of pyrazolo[3,4-g]quinoxaline derivatives.

artículo científico publicado en 2010

Synthesis and biological activity of pyrazole analogues of the staurosporine aglycon K252c.

artículo científico publicado en 2016

Synthesis and biological evaluation of oxindoles and benzimidazolinones derivatives.

artículo científico publicado en 2004

Synthesis and in vitro antiproliferative activities of quinoline derivatives.

artículo científico publicado en 2010

Synthesis and molecular modeling study of new trimeric quinoline derivatives

artículo científico publicado en 2011

Synthesis and preliminary in vitro kinase inhibition evaluation of new diversely substituted pyrido[3,4-g]quinazoline derivatives

artículo científico publicado en 2016

Synthesis of pyrazolo[4,3-a]phenanthridines, a new scaffold for Pim kinase inhibition

artículo científico publicado en 2014

Synthesis, Pim kinase inhibitory potencies and in vitro antiproliferative activities of diversely substituted pyrrolo[2,3-a]carbazoles.

artículo científico publicado en 2010

Synthesis, kinase inhibitory potencies and in vitro antiproliferative activity of isoindigo and 7'-azaisoindigo derivatives substituted by Sonogashira cross-coupling.

artículo científico publicado en 2009

Synthesis, kinase inhibitory potencies, and in vitro antiproliferative evaluation of new Pim kinase inhibitors

artículo científico publicado en 2009

Synthesis, protein kinase inhibitory potencies, and in vitro antiproliferative activities of meridianin derivatives.

artículo científico publicado en 2011

Triple helix-forming oligonucleotides conjugated to indolocarbazole poisons direct topoisomerase I-mediated DNA cleavage to a specific site.

artículo científico publicado en 2001

Lista de obras de Pascale Moreau

A Kinase Inhibitor with Anti-Pim Kinase Activity is a Potent and Selective Cytotoxic Agent Toward Acute Myeloid Leukemia

Analogues of antifungal tjipanazoles from rebeccamycin.

Biological evaluation of glycosyl-isoindigo derivatives against the pathogenic agents of tropical diseases (malaria, Chagas disease, leishmaniasis and human African trypanosomiasis).

Discovery of pyrido[3,4-g]quinazoline derivatives as CMGC family protein kinase inhibitors: Design, synthesis, inhibitory potency and X-ray co-crystal structure

Heteroaromatic Pim Kinase Inhibitors Containing a Pyrazole Moiety.

Identification of pyrrolo[2,3-g]indazoles as new Pim kinase inhibitors.

In-vitro antiproliferative activities and kinase inhibitory potencies of glycosyl-isoindigo derivatives.

Kaposi's sarcoma herpesvirus lytic replication compromises apoptotic response to p53 reactivation in virus-induced lymphomas.

Kinase inhibitory potencies and in vitro antiproliferative activities of N-10 substituted pyrrolo[2,3-a]carbazole derivatives.

New N-1,N-10-bridged pyrrolo[2,3-a]carbazole-3-carbaldehydes: synthesis and biological activities

New pyrido[3,4-g]quinazoline derivatives as CLK1 and DYRK1A inhibitors: synthesis, biological evaluation and binding mode analysis

Pim Kinases Promote Migration and Metastatic Growth of Prostate Cancer Xenografts

Rebeccamycin analogues bearing amine substituents or other groups on the sugar moiety

Rebeccamycin derivatives as dual DNA-damaging agents and potent checkpoint kinase 1 inhibitors.

Semi-synthesis, topoisomerase I and kinases inhibitory properties, and antiproliferative activities of new rebeccamycin derivatives.

Syntheses and biological activities (topoisomerase inhibition and antitumor and antimicrobial properties) of rebeccamycin analogues bearing modified sugar moieties and substituted on the imide nitrogen with a methyl group.

Syntheses and biological activities of rebeccamycin analogues. Introduction of a halogenoacetyl substituent

Synthesis and activities of new indolopyrrolobenzodiazepine derivatives toward acute myeloid leukemia cells

Synthesis and antiproliferative activities of diversely substituted glycosyl-isoindigo derivatives.

Synthesis and antiproliferative activities of indolin-2-one derivatives bearing amino acid moieties

Synthesis and antiproliferative activities of isoindigo and azaisoindigo derivatives.

Synthesis and biological activities of 4-substituted pyrrolo[2,3-a]carbazole Pim kinase inhibitors.

Synthesis and biological activities of aminopyrimidyl-indoles structurally related to meridianins.

Synthesis and biological activities of new di- and trimeric quinoline derivatives.

Synthesis and biological activities of pyrazolo[3,4-g]quinoxaline derivatives.

Synthesis and biological activity of pyrazole analogues of the staurosporine aglycon K252c.

Synthesis and biological evaluation of oxindoles and benzimidazolinones derivatives.

Synthesis and in vitro antiproliferative activities of quinoline derivatives.

Synthesis and molecular modeling study of new trimeric quinoline derivatives

Synthesis and preliminary in vitro kinase inhibition evaluation of new diversely substituted pyrido[3,4-g]quinazoline derivatives

Synthesis of pyrazolo[4,3-a]phenanthridines, a new scaffold for Pim kinase inhibition

Synthesis, Pim kinase inhibitory potencies and in vitro antiproliferative activities of diversely substituted pyrrolo[2,3-a]carbazoles.

Synthesis, kinase inhibitory potencies and in vitro antiproliferative activity of isoindigo and 7'-azaisoindigo derivatives substituted by Sonogashira cross-coupling.

Synthesis, kinase inhibitory potencies, and in vitro antiproliferative evaluation of new Pim kinase inhibitors

Synthesis, protein kinase inhibitory potencies, and in vitro antiproliferative activities of meridianin derivatives.

Triple helix-forming oligonucleotides conjugated to indolocarbazole poisons direct topoisomerase I-mediated DNA cleavage to a specific site.