Lista de obras - Marcel B Bally - Dominio Público Uruguay

3'-Phosphoadenosine 5'-phosphosulfate synthase 1 (PAPSS1) knockdown sensitizes non-small cell lung cancer cells to DNA damaging agents

artículo científico publicado en 2015

A Low Carbohydrate, High Protein Diet Slows Tumor Growth and Prevents Cancer Initiation

artículo científico publicado en 2011

A Perspective - can copper complexes be developed as a novel class of therapeutics?

artículo científico publicado en 2017

A new quinoline-based chemical probe inhibits the autophagy-related cysteine protease ATG4B

scientific article published in Scientific Reports

A novel liposomal irinotecan formulation with significant anti-tumour activity: use of the divalent cation ionophore A23187 and copper-containing liposomes to improve drug retention.

artículo científico publicado en 2007

A simple passive equilibration method for loading carboplatin into pre-formed liposomes incubated with ethanol as a temperature dependent permeability enhancer.

artículo científico publicado en 2017

An evaluation of transmembrane ion gradient-mediated encapsulation of topotecan within liposomes

artículo científico publicado en 2004

An immune response to ovalbumin covalently coupled to liposomes is prevented when the liposomes used contain doxorubicin

scientific article published on 01 December 1997

Antitumor efficacy of oblimersen Bcl-2 antisense oligonucleotide alone and in combination with vinorelbine in xenograft models of human non-small cell lung cancer

artículo científico publicado en 2004

Attaching histidine-tagged peptides and proteins to lipid-based carriers through use of metal-ion-chelating lipids.

artículo científico publicado en 2002

Cationic Liposome–Plasmid DNA Complexes Used for Gene Transfer Retain a Significant Trapped Volume ⬇️

artículo científico publicado el 1 de enero de 1998

Chemodosimetry of in vivo tumor liposomal drug concentration using MRI.

artículo científico publicado en 2006

Combined RNAi-mediated suppression of Rictor and EGFR resulted in complete tumor regression in an orthotopic glioblastoma tumor model

artículo científico publicado en 2013

Copper (II) complexes of bidentate ligands exhibit potent anti-cancer activity regardless of platinum sensitivity status

artículo científico publicado en 2017

Copper-CX-5461: A novel liposomal formulation for a small molecule rRNA synthesis inhibitor

artículo científico publicado en 2018

Decreased levels of hypoxic cells in gefitinib treated ER+ HER-2 overexpressing MCF-7 breast cancer tumors are associated with hyperactivation of the mTOR pathway: therapeutic implications for combination therapy with rapamycin.

artículo científico publicado en 2007

Determination of an optimal dosing schedule for combining Irinophore C™ and temozolomide in an orthotopic model of glioblastoma.

artículo científico publicado en 2015

Development and optimization of an injectable formulation of copper diethyldithiocarbamate, an active anticancer agent.

artículo científico publicado en 2017

Development of a copper-clioquinol formulation suitable for intravenous use.

artículo científico publicado en 2017

Development of a liposomal nanoparticle formulation of 5-Fluorouracil for parenteral administration: Formulation design, pharmacokinetics and efficacy

artículo científico publicado en 2010

Efficient delivery of Antennapedia homeodomain fused to CTL epitope with liposomes into dendritic cells results in the activation of CD8+ T cells

Electrostatically mediated interactions between cationic lipid-DNA particles and an anionic surface

artículo científico publicado en 1999

Encapsulation of doxorubicin into thermosensitive liposomes via complexation with the transition metal manganese

artículo científico publicado en 2005

Four human t(11;14)(q13;q32)-containing cell lines having classic and variant features of Mantle Cell Lymphoma.

artículo científico publicado en 2005

Gene silencing in the development of personalized cancer treatment: the targets, the agents and the delivery systems.

artículo científico publicado en 2006

Harnessing the potential of lipid-based nanomedicines for type-specific ovarian cancer treatments.

artículo científico publicado en 2014

Histone Deacetylase Inhibitors Synergize with Catalytic Inhibitors of EZH2 to Exhibit Antitumor Activity in Small Cell Carcinoma of the Ovary, Hypercalcemic Type

scientific article published on 19 September 2018

Identification of breast cancer cell subtypes sensitive to ATG4B inhibition.

artículo científico publicado en 2016

Improved retention of idarubicin after intravenous injection obtained for cholesterol-free liposomes

artículo científico publicado en 2002

In vitro and in vivo characterization of doxorubicin and vincristine coencapsulated within liposomes through use of transition metal ion complexation and pH gradient loading

artículo científico publicado en 2004

In vitro assay for measuring real time topotecan release from liposomes: release kinetics and cellular internalization

artículo científico publicado en 2017

Induction of autophagy is an early response to gefitinib and a potential therapeutic target in breast cancer

artículo científico publicado en 2013

Influence of poly(ethylene glycol) grafting density and polymer length on liposomes: relating plasma circulation lifetimes to protein binding.

artículo científico publicado en 2007

Intermembrane transfer of polyethylene glycol-modified phosphatidylethanolamine as a means to reveal surface-associated binding ligands on liposomes.

artículo científico publicado en 2001

Intratumor distribution of doxorubicin following i.v. administration of drug encapsulated in egg phosphatidylcholine/cholesterol liposomes

artículo científico publicado en 1997

Intravenous pretreatment with empty pH gradient liposomes alters the pharmacokinetics and toxicity of doxorubicin through in vivo active drug encapsulation

scientific article published on 01 January 1999

Irinophore C™, a lipid nanoparticle formulation of irinotecan, abrogates the gastrointestinal effects of irinotecan in a rat model of clinical toxicities

artículo científico publicado en 2014

Irinophore C™, a lipid-based nanoparticulate formulation of irinotecan, is more effective than free irinotecan when used to treat an orthotopic glioblastoma model.

artículo científico publicado en 2011

Irinotecan-cisplatin interactions assessed in cell-based screening assays: cytotoxicity, drug accumulation and DNA adduct formation in an NSCLC cell line.

artículo científico publicado en 2006

Lipid-based nanoformulation of irinotecan: dual mechanism of action allows for combination chemo/angiogenic therapy

scientific article published on 01 November 2011

Liposomal drug delivery: recent patents and emerging opportunities

scientific article published on January 2007

Liposomal irinotecan: formulation development and therapeutic assessment in murine xenograft models of colorectal cancer.

artículo científico publicado en 2004

Mastoparan is a membranolytic anti-cancer peptide that works synergistically with gemcitabine in a mouse model of mammary carcinoma.

artículo científico publicado en 2016

Multivalent Rituximab Lipid Nanoparticles as Improved Lymphoma Therapies: Indirect Mechanisms of Action and In Vivo Activity ⬇️

artículo científico publicado el 20 de octubre de 2011

Nano-encapsulation of arsenic trioxide enhances efficacy against murine lymphoma model while minimizing its impact on ovarian reserve in vitro and in vivo

artículo científico publicado en 2013

PRCosomes: pretty reactive complexes formed in liposomes

artículo científico publicado en 2016

Phosphatidylethanolamine mediated destabilization of lipid-based pDNA delivery systems.

artículo científico publicado en 2003

Plasma protein binding, lipoprotein distribution and uptake of free and lipid-associated BCL-2 antisense oligodeoxynucleotides (G3139) in human melanoma cells.

artículo científico publicado en 2002

Poly(ethylene glycol)-modified phospholipids prevent aggregation during covalent conjugation of proteins to liposomes

scientific article published on 01 March 1995

Preparation, Characterization, and Biological Analysis of Liposomal Formulations of Vincristine

article

Rictor and integrin-linked kinase interact and regulate Akt phosphorylation and cancer cell survival

artículo científico publicado en 2008

Self-assembling DNA-lipid particles for gene transfer

artículo científico publicado en 1997

Silencing Bcl-2 in models of mantle cell lymphoma is associated with decreases in cyclin D1, nuclear factor-kappaB, p53, bax, and p27 levels.

artículo científico publicado en 2008

Sphingomyelin-cholesterol liposomes significantly enhance the pharmacokinetic and therapeutic properties of vincristine in murine and human tumour models

artículo científico publicado en 1995

Sulfonation, an underexploited area: from skeletal development to infectious diseases and cancer.

artículo científico publicado en 2016

Suppression of Her2/neu expression through ILK inhibition is regulated by a pathway involving TWIST and YB-1

artículo científico publicado en 2010

Synthetic lethality in lung cancer and translation to clinical therapies

artículo científico publicado en 2016

Targeting of antibody conjugated, phosphatidylserine-containing liposomes to vascular cell adhesion molecule 1 for controlled thrombogenesis.

artículo científico publicado en 2003

Targeting tumor hypoxia: suppression of breast tumor growth and metastasis by novel carbonic anhydrase IX inhibitors.

artículo científico publicado en 2011

The formulation of lipid-based nanotechnologies for the delivery of fixed dose anticancer drug combinations.

artículo científico publicado en 2005

The functional roles of poly(ethylene glycol)-lipid and lysolipid in the drug retention and release from lysolipid-containing thermosensitive liposomes in vitro and in vivo

artículo científico publicado en 2010

The histone methyltransferase EZH2 is a therapeutic target in small cell carcinoma of the ovary, hypercalcaemic type.

artículo científico publicado en 2017

Topophore C: a liposomal nanoparticle formulation of topotecan for treatment of ovarian cancer ⬇️

artículo científico publicado el 22 de mayo de 2012

Topotecan and Doxorubicin Combination to Treat Recurrent Ovarian Cancer: The Influence of Drug Exposure Time and Delivery Systems to Achieve Optimum Therapeutic Activity ⬇️

artículo científico publicado el 9 de enero de 2013

Transition Metal Ions Promote the Bioavailability of Hydrophobic Therapeutics: Cu and Zn Interactions with RNA Polymerase I Inhibitor CX5461.

artículo científico publicado en 2018

Unique therapeutic properties and preparation methodology of multivalent rituximab-lipid nanoparticles.

artículo científico publicado en 2017

Use of a passive equilibration methodology to encapsulate cisplatin into preformed thermosensitive liposomes

artículo científico publicado en 2007

Use of poly(ethylene glycol)-lipid conjugates to regulate the surface attributes and transfection activity of lipid-DNA particles

artículo científico publicado en 2000

Using Pharmacokinetic Profiles and Digital Quantification of Stained Tissue Microarrays as a Medium-Throughput, Quantitative Method for Measuring the Kinetics of Early Signaling Changes Following Integrin-Linked Kinase Inhibition in an In Vivo Model

artículo científico publicado en 2015

Validation of a high-performance liquid chromatographic assay method for quantification of total vincristine sulfate in human plasma following administration of vincristine sulfate liposome injection

artículo científico publicado en 1997

Vincristine-induced dermal toxicity is significantly reduced when the drug is given in liposomes

scientific article published on 01 January 1996

pH gradient loading of anthracyclines into cholesterol-free liposomes: enhancing drug loading rates through use of ethanol.

artículo científico publicado en 2004

Lista de obras de Marcel B Bally

3'-Phosphoadenosine 5'-phosphosulfate synthase 1 (PAPSS1) knockdown sensitizes non-small cell lung cancer cells to DNA damaging agents

A Low Carbohydrate, High Protein Diet Slows Tumor Growth and Prevents Cancer Initiation

A Perspective - can copper complexes be developed as a novel class of therapeutics?

A new quinoline-based chemical probe inhibits the autophagy-related cysteine protease ATG4B

A novel liposomal irinotecan formulation with significant anti-tumour activity: use of the divalent cation ionophore A23187 and copper-containing liposomes to improve drug retention.

A simple passive equilibration method for loading carboplatin into pre-formed liposomes incubated with ethanol as a temperature dependent permeability enhancer.

An evaluation of transmembrane ion gradient-mediated encapsulation of topotecan within liposomes

An immune response to ovalbumin covalently coupled to liposomes is prevented when the liposomes used contain doxorubicin

Antitumor efficacy of oblimersen Bcl-2 antisense oligonucleotide alone and in combination with vinorelbine in xenograft models of human non-small cell lung cancer

Attaching histidine-tagged peptides and proteins to lipid-based carriers through use of metal-ion-chelating lipids.

Cationic Liposome–Plasmid DNA Complexes Used for Gene Transfer Retain a Significant Trapped Volume ⬇️

Chemodosimetry of in vivo tumor liposomal drug concentration using MRI.

Combined RNAi-mediated suppression of Rictor and EGFR resulted in complete tumor regression in an orthotopic glioblastoma tumor model

Copper (II) complexes of bidentate ligands exhibit potent anti-cancer activity regardless of platinum sensitivity status

Copper-CX-5461: A novel liposomal formulation for a small molecule rRNA synthesis inhibitor

Decreased levels of hypoxic cells in gefitinib treated ER+ HER-2 overexpressing MCF-7 breast cancer tumors are associated with hyperactivation of the mTOR pathway: therapeutic implications for combination therapy with rapamycin.

Determination of an optimal dosing schedule for combining Irinophore C™ and temozolomide in an orthotopic model of glioblastoma.

Development and optimization of an injectable formulation of copper diethyldithiocarbamate, an active anticancer agent.

Development of a copper-clioquinol formulation suitable for intravenous use.

Development of a liposomal nanoparticle formulation of 5-Fluorouracil for parenteral administration: Formulation design, pharmacokinetics and efficacy

Efficient delivery of Antennapedia homeodomain fused to CTL epitope with liposomes into dendritic cells results in the activation of CD8+ T cells

Electrostatically mediated interactions between cationic lipid-DNA particles and an anionic surface

Encapsulation of doxorubicin into thermosensitive liposomes via complexation with the transition metal manganese

Four human t(11;14)(q13;q32)-containing cell lines having classic and variant features of Mantle Cell Lymphoma.

Gene silencing in the development of personalized cancer treatment: the targets, the agents and the delivery systems.

Harnessing the potential of lipid-based nanomedicines for type-specific ovarian cancer treatments.

Histone Deacetylase Inhibitors Synergize with Catalytic Inhibitors of EZH2 to Exhibit Antitumor Activity in Small Cell Carcinoma of the Ovary, Hypercalcemic Type

Identification of breast cancer cell subtypes sensitive to ATG4B inhibition.

Improved retention of idarubicin after intravenous injection obtained for cholesterol-free liposomes

In vitro and in vivo characterization of doxorubicin and vincristine coencapsulated within liposomes through use of transition metal ion complexation and pH gradient loading

In vitro assay for measuring real time topotecan release from liposomes: release kinetics and cellular internalization

Induction of autophagy is an early response to gefitinib and a potential therapeutic target in breast cancer

Influence of poly(ethylene glycol) grafting density and polymer length on liposomes: relating plasma circulation lifetimes to protein binding.

Intermembrane transfer of polyethylene glycol-modified phosphatidylethanolamine as a means to reveal surface-associated binding ligands on liposomes.

Intratumor distribution of doxorubicin following i.v. administration of drug encapsulated in egg phosphatidylcholine/cholesterol liposomes

Intravenous pretreatment with empty pH gradient liposomes alters the pharmacokinetics and toxicity of doxorubicin through in vivo active drug encapsulation

Irinophore C™, a lipid nanoparticle formulation of irinotecan, abrogates the gastrointestinal effects of irinotecan in a rat model of clinical toxicities

Irinophore C™, a lipid-based nanoparticulate formulation of irinotecan, is more effective than free irinotecan when used to treat an orthotopic glioblastoma model.

Irinotecan-cisplatin interactions assessed in cell-based screening assays: cytotoxicity, drug accumulation and DNA adduct formation in an NSCLC cell line.

Lipid-based nanoformulation of irinotecan: dual mechanism of action allows for combination chemo/angiogenic therapy

Liposomal drug delivery: recent patents and emerging opportunities

Liposomal irinotecan: formulation development and therapeutic assessment in murine xenograft models of colorectal cancer.

Mastoparan is a membranolytic anti-cancer peptide that works synergistically with gemcitabine in a mouse model of mammary carcinoma.

Multivalent Rituximab Lipid Nanoparticles as Improved Lymphoma Therapies: Indirect Mechanisms of Action and In Vivo Activity ⬇️

Nano-encapsulation of arsenic trioxide enhances efficacy against murine lymphoma model while minimizing its impact on ovarian reserve in vitro and in vivo

PRCosomes: pretty reactive complexes formed in liposomes

Phosphatidylethanolamine mediated destabilization of lipid-based pDNA delivery systems.

Plasma protein binding, lipoprotein distribution and uptake of free and lipid-associated BCL-2 antisense oligodeoxynucleotides (G3139) in human melanoma cells.

Poly(ethylene glycol)-modified phospholipids prevent aggregation during covalent conjugation of proteins to liposomes

Preparation, Characterization, and Biological Analysis of Liposomal Formulations of Vincristine

Rictor and integrin-linked kinase interact and regulate Akt phosphorylation and cancer cell survival

Self-assembling DNA-lipid particles for gene transfer

Silencing Bcl-2 in models of mantle cell lymphoma is associated with decreases in cyclin D1, nuclear factor-kappaB, p53, bax, and p27 levels.

Sphingomyelin-cholesterol liposomes significantly enhance the pharmacokinetic and therapeutic properties of vincristine in murine and human tumour models

Sulfonation, an underexploited area: from skeletal development to infectious diseases and cancer.

Suppression of Her2/neu expression through ILK inhibition is regulated by a pathway involving TWIST and YB-1

Synthetic lethality in lung cancer and translation to clinical therapies

Targeting of antibody conjugated, phosphatidylserine-containing liposomes to vascular cell adhesion molecule 1 for controlled thrombogenesis.

Targeting tumor hypoxia: suppression of breast tumor growth and metastasis by novel carbonic anhydrase IX inhibitors.

The formulation of lipid-based nanotechnologies for the delivery of fixed dose anticancer drug combinations.

The functional roles of poly(ethylene glycol)-lipid and lysolipid in the drug retention and release from lysolipid-containing thermosensitive liposomes in vitro and in vivo

The histone methyltransferase EZH2 is a therapeutic target in small cell carcinoma of the ovary, hypercalcaemic type.

Topophore C: a liposomal nanoparticle formulation of topotecan for treatment of ovarian cancer ⬇️

Topotecan and Doxorubicin Combination to Treat Recurrent Ovarian Cancer: The Influence of Drug Exposure Time and Delivery Systems to Achieve Optimum Therapeutic Activity ⬇️

Transition Metal Ions Promote the Bioavailability of Hydrophobic Therapeutics: Cu and Zn Interactions with RNA Polymerase I Inhibitor CX5461.

Unique therapeutic properties and preparation methodology of multivalent rituximab-lipid nanoparticles.

Use of a passive equilibration methodology to encapsulate cisplatin into preformed thermosensitive liposomes

Use of poly(ethylene glycol)-lipid conjugates to regulate the surface attributes and transfection activity of lipid-DNA particles

Using Pharmacokinetic Profiles and Digital Quantification of Stained Tissue Microarrays as a Medium-Throughput, Quantitative Method for Measuring the Kinetics of Early Signaling Changes Following Integrin-Linked Kinase Inhibition in an In Vivo Model

Validation of a high-performance liquid chromatographic assay method for quantification of total vincristine sulfate in human plasma following administration of vincristine sulfate liposome injection

Vincristine-induced dermal toxicity is significantly reduced when the drug is given in liposomes

pH gradient loading of anthracyclines into cholesterol-free liposomes: enhancing drug loading rates through use of ethanol.