Lista de obras -

AMPA receptor-mediated modulation of inward rectifier K+ channels in astrocytes of mouse hippocampus.

artículo científico publicado en 2002

Astrocytes in the hippocampus of patients with temporal lobe epilepsy display changes in potassium conductances.

artículo científico publicado en 2000

Cebranopadol: a novel potent analgesic nociceptin/orphanin FQ peptide and opioid receptor agonist.

artículo científico publicado en 2014

Changes in flip/flop splicing of astroglial AMPA receptors in human temporal lobe epilepsy.

artículo científico publicado en 2002

Differential contribution of opioid and noradrenergic mechanisms of tapentadol in rat models of nociceptive and neuropathic pain.

artículo científico publicado en 2010

Discovery of Spiro[cyclohexane-dihydropyrano[3,4-b]indole]-amines as Potent NOP and Opioid Receptor Agonists

artículo científico publicado en 2014

Discovery of a Potent Analgesic NOP and Opioid Receptor Agonist: Cebranopadol

artículo científico publicado en 2014

Effects of the mas-related gene (Mrg) C receptor agonist BAM6-22 on nociceptive reflex activity in naive, monoarthritic and mononeuropathic rats after intraplantar and intrathecal administration

artículo científico publicado en 2015

Functional analysis of embryonic stem cell-derived glial cells after integration into hippocampal slice cultures.

artículo científico publicado en 2008

Functional network integration of embryonic stem cell-derived astrocytes in hippocampal slice cultures.

artículo científico publicado en 2003

Functional plasticity of the N/OFQ-NOP receptor system determines analgesic properties of NOP receptor agonists

artículo científico publicado en 2014

Identification of versican as an isolectin B4-binding glycoprotein from mammalian spinal cord tissue.

artículo científico publicado en 2005

Inhibition of N-type voltage-activated calcium channels in rat dorsal root ganglion neurons by P2Y receptors is a possible mechanism of ADP-induced analgesia.

artículo científico publicado en 2004

Inhibition of experimental visceral pain in rodents by cebranopadol

scientific article published on 01 June 2019

Investigation of TRPV1 loss-of-function phenotypes in TRPV1 Leu206Stop mice generated by N-ethyl-N-nitrosourea mutagenesis.

artículo científico publicado en 2018

Investigation of TRPV1 loss-of-function phenotypes in transgenic shRNA expressing and knockout mice

artículo científico publicado en 2007

Lack of synergistic interaction between the two mechanisms of action of tapentadol in gastrointestinal transit

scientific article published on 26 February 2014

Late onset and increasing expression of the gap junction protein connexin30 in adult murine brain and long-term cultured astrocytes.

artículo científico publicado en 1999

Lesion-induced changes of electrophysiological properties in astrocytes of the rat dentate gyrus

artículo científico publicado en 1999

Mechanical hyperalgesia in rats with diabetic polyneuropathy is selectively inhibited by local peripheral nociceptin/orphanin FQ receptor and µ-opioid receptor agonism.

artículo científico publicado en 2015

Metabotropic P2Y receptors inhibit P2X3 receptor-channels via G protein-dependent facilitation of their desensitization.

artículo científico publicado en 2007

Neuronally produced versican V2 renders C-fiber nociceptors IB4 -positive

artículo científico publicado en 2015

Nociceptin/orphanin FQ opioid peptide (NOP) receptor and µ-opioid peptide (MOP) receptors both contribute to the anti-hypersensitive effect of cebranopadol in a rat model of arthritic pain

artículo científico publicado en 2018

Nociceptin/orphanin FQ opioid peptide-receptor expression in pachyonychia congenita

scientific article published on 16 October 2018

Opioid-type Respiratory Depressant Side Effects of Cebranopadol in Rats Are Limited by Its Nociceptin/Orphanin FQ Peptide Receptor Agonist Activity

artículo científico publicado en 2017

Selectivity profiling of NOP, MOP, DOP and KOP receptor antagonists in the rat spinal nerve ligation model of mononeuropathic pain

artículo científico publicado en 2018

Spinal vs. supraspinal antinociceptive activity of the adenosine A(1) receptor agonist cyclopentyl-adenosine in rats with inflammation.

artículo científico publicado en 2004

Spinal-supraspinal and intrinsic μ-opioid receptor agonist-norepinephrine reuptake inhibitor (MOR-NRI) synergy of tapentadol in diabetic heat hyperalgesia in mice

artículo científico publicado en 2013

Synergistic interaction between the agonism of cebranopadol at nociceptin/orphanin FQ and classical opioid receptors in the rat spinal nerve ligation model

artículo científico publicado en 2018

Synergistic interaction between the two mechanisms of action of tapentadol in analgesia

artículo científico publicado en 2011

[EXPRESS] RNA interference-based functional knockdown of the voltage gated potassium channel Kv7.2 in dorsal root ganglion neurons after in vitro and in vivo gene transfer by adeno-associated virus (AAV) vectors.

artículo científico publicado en 2017

[Tapentadol: with two mechanisms of action in one molecule effective against nociceptive and neuropathic pain. Preclinical overview]

scientific article published on 01 February 2011

Lista de obras de

AMPA receptor-mediated modulation of inward rectifier K+ channels in astrocytes of mouse hippocampus.

Astrocytes in the hippocampus of patients with temporal lobe epilepsy display changes in potassium conductances.

Cebranopadol: a novel potent analgesic nociceptin/orphanin FQ peptide and opioid receptor agonist.

Changes in flip/flop splicing of astroglial AMPA receptors in human temporal lobe epilepsy.

Differential contribution of opioid and noradrenergic mechanisms of tapentadol in rat models of nociceptive and neuropathic pain.

Discovery of Spiro[cyclohexane-dihydropyrano[3,4-b]indole]-amines as Potent NOP and Opioid Receptor Agonists

Discovery of a Potent Analgesic NOP and Opioid Receptor Agonist: Cebranopadol

Effects of the mas-related gene (Mrg) C receptor agonist BAM6-22 on nociceptive reflex activity in naive, monoarthritic and mononeuropathic rats after intraplantar and intrathecal administration

Functional analysis of embryonic stem cell-derived glial cells after integration into hippocampal slice cultures.

Functional network integration of embryonic stem cell-derived astrocytes in hippocampal slice cultures.

Functional plasticity of the N/OFQ-NOP receptor system determines analgesic properties of NOP receptor agonists

Identification of versican as an isolectin B4-binding glycoprotein from mammalian spinal cord tissue.

Inhibition of N-type voltage-activated calcium channels in rat dorsal root ganglion neurons by P2Y receptors is a possible mechanism of ADP-induced analgesia.

Inhibition of experimental visceral pain in rodents by cebranopadol

Investigation of TRPV1 loss-of-function phenotypes in TRPV1 Leu206Stop mice generated by N-ethyl-N-nitrosourea mutagenesis.

Investigation of TRPV1 loss-of-function phenotypes in transgenic shRNA expressing and knockout mice

Lack of synergistic interaction between the two mechanisms of action of tapentadol in gastrointestinal transit

Late onset and increasing expression of the gap junction protein connexin30 in adult murine brain and long-term cultured astrocytes.

Lesion-induced changes of electrophysiological properties in astrocytes of the rat dentate gyrus

Mechanical hyperalgesia in rats with diabetic polyneuropathy is selectively inhibited by local peripheral nociceptin/orphanin FQ receptor and µ-opioid receptor agonism.

Metabotropic P2Y receptors inhibit P2X3 receptor-channels via G protein-dependent facilitation of their desensitization.

Neuronally produced versican V2 renders C-fiber nociceptors IB4 -positive

Nociceptin/orphanin FQ opioid peptide (NOP) receptor and µ-opioid peptide (MOP) receptors both contribute to the anti-hypersensitive effect of cebranopadol in a rat model of arthritic pain

Nociceptin/orphanin FQ opioid peptide-receptor expression in pachyonychia congenita

Opioid-type Respiratory Depressant Side Effects of Cebranopadol in Rats Are Limited by Its Nociceptin/Orphanin FQ Peptide Receptor Agonist Activity

Selectivity profiling of NOP, MOP, DOP and KOP receptor antagonists in the rat spinal nerve ligation model of mononeuropathic pain

Spinal vs. supraspinal antinociceptive activity of the adenosine A(1) receptor agonist cyclopentyl-adenosine in rats with inflammation.

Spinal-supraspinal and intrinsic μ-opioid receptor agonist-norepinephrine reuptake inhibitor (MOR-NRI) synergy of tapentadol in diabetic heat hyperalgesia in mice

Synergistic interaction between the agonism of cebranopadol at nociceptin/orphanin FQ and classical opioid receptors in the rat spinal nerve ligation model

Synergistic interaction between the two mechanisms of action of tapentadol in analgesia

[EXPRESS] RNA interference-based functional knockdown of the voltage gated potassium channel Kv7.2 in dorsal root ganglion neurons after in vitro and in vivo gene transfer by adeno-associated virus (AAV) vectors.

[Tapentadol: with two mechanisms of action in one molecule effective against nociceptive and neuropathic pain. Preclinical overview]