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A betulinic acid derivative SH479 inhibits collagen-induced arthritis by modulating T cell differentiation and cytokine balance.

artículo científico publicado en 2016

Correction to: Increasing targeting scope of adenosine base editors in mouse and rat embryos through fusion of TadA deaminase with Cas9 variants

scientific article published on 01 September 2019

Dual Targeting of Bile Acid Receptor-1 (TGR5) and Farnesoid X Receptor (FXR) Prevents Estrogen-Dependent Bone Loss in Mice

artículo científico publicado en 2019

Evidence that an early pregnancy causes a persistent decrease in the number of functional mammary epithelial stem cells--implications for pregnancy-induced protection against breast cancer

artículo científico publicado en 2008

Exploring Rak tyrosine kinase function in breast cancer.

artículo científico publicado en 2009

G-protein coupled receptor 124 (GPR124) in endothelial cells regulates vascular endothelial growth factor (VEGF)-induced tumor angiogenesis.

artículo científico publicado en 2014

GPR116, an adhesion G-protein-coupled receptor, promotes breast cancer metastasis via the Gαq-p63RhoGEF-Rho GTPase pathway.

artículo científico publicado en 2013

Genome-wide transcriptome profiling of homologous recombination DNA repair

artículo científico publicado en 2014

Increasing targeting scope of adenosine base editors in mouse and rat embryos through fusion of TadA deaminase with Cas9 variants.

artículo científico publicado en 2018

Inhibition of Rspo-Lgr4 Facilitates Checkpoint Blockade Therapy by Switching Macrophage Polarization

artículo científico publicado en 2018

KiSS1 and its G-protein-coupled receptor GPR54 in cancer development and metastasis

artículo científico publicado el 1 de diciembre de 2012

KiSS1-induced GPR54 signaling inhibits breast cancer cell migration and epithelial-mesenchymal transition via protein kinase D1.

artículo científico publicado en 2014

Kisspeptin/GPR54 signaling restricts antiviral innate immune response through regulating calcineurin phosphatase activity

artículo científico publicado en 2018

LGR4 is a receptor for RANKL and negatively regulates osteoclast differentiation and bone resorption.

artículo científico publicado en 2016

LGR4 modulates breast cancer initiation, metastasis, and cancer stem cells.

artículo científico publicado en 2017

LGR4/GPR48 inactivation leads to aniridia-genitourinary anomalies-mental retardation syndrome defects.

artículo científico publicado en 2014

Lentivirus-mediated oncogene introduction into mammary cells in vivo induces tumors.

artículo científico publicado en 2008

Leucine-rich repeat-containing G protein-coupled receptor 4 (Lgr4) is necessary for prostate cancer metastasis via epithelial-mesenchymal transition.

artículo científico publicado en 2017

Leucine-rich repeat-containing G protein-coupled receptor 4 facilitates vesicular stomatitis virus infection by binding vesicular stomatitis virus glycoprotein.

artículo científico publicado en 2017

Lgr4 is a key regulator of prostate development and prostate stem cell differentiation.

artículo científico publicado en 2013

Lgr4 regulates mammary gland development and stem cell activity through the pluripotency transcription factor Sox2.

artículo científico publicado en 2013

Loss of Lgr4 inhibits differentiation, migration and apoptosis, and promotes proliferation in bone mesenchymal stem cells

scientific article published on 07 December 2018

Metabolite-Sensing G Protein Coupled Receptor TGR5 Protects Host From Viral Infection Through Amplifying Type I Interferon Responses

article

PSGR promotes prostatic intraepithelial neoplasia and prostate cancer xenograft growth through NF-κB.

artículo científico publicado en 2014

Prostate-Specific G-Protein Coupled Receptor, an Emerging Biomarker Regulating Inflammation and Prostate Cancer Invasion.

artículo científico publicado en 2016

Prostate-specific G-protein-coupled receptor collaborates with loss of PTEN to promote prostate cancer progression

artículo científico publicado en 2015

Regulation of body length and bone mass by Gpr126/Adgrg6

scientific article published on 20 March 2020

Repression of Mammalian Target of Rapamycin Complex 1 Inhibits Intestinal Regeneration in Acute Inflammatory Bowel Disease Models

artículo científico publicado en 2015

The role of GPCRs in bone diseases and dysfunctions

artículo científico publicado en 2019