Lista de obras - Amjad Javed - Dominio Público Uruguay

A Runx2 threshold for the cleidocranial dysplasia phenotype

artículo científico publicado en 2008

Alterations in intranuclear localization of Runx2 affect biological activity

artículo científico publicado en 2006

Altered chromatin modifications in AML1/RUNX1 breakpoint regions involved in (8;21) translocation.

artículo científico publicado en 2009

Analysis of in vivo gene expression using epitope-tagged proteins

artículo científico publicado en 2004

BMP2 commitment to the osteogenic lineage involves activation of Runx2 by DLX3 and a homeodomain transcriptional network.

artículo científico publicado en 2006

Biphasic peptide amphiphile nanomatrix embedded with hydroxyapatite nanoparticles for stimulated osteoinductive response.

artículo científico publicado en 2011

CBFa(AML/PEBP2)-related elements in the TGF-beta type I receptor promoter and expression with osteoblast differentiation

artículo científico publicado en 1998

CCAAT/enhancer-binding proteins (C/EBP) beta and delta activate osteocalcin gene transcription and synergize with Runx2 at the C/EBP element to regulate bone-specific expression.

artículo científico publicado en 2001

Canonical WNT Signaling Promotes Osteogenesis by Directly StimulatingRunx2Gene Expression

artículo científico publicado en 2005

Cbfbeta interacts with Runx2 and has a critical role in bone development

scientific journal article

Chondrocyte-specific regulatory activity of Runx2 is essential for survival and skeletal development

artículo científico publicado en 2011

Chromatin immunoprecipitation

scientific article published on 01 January 2004

Chromatin immunoprecipitation assays: application of ChIP-on-chip for defining dynamic transcriptional mechanisms in bone cells.

artículo científico publicado en 2008

Combinatorial organization of the transcriptional regulatory machinery in biological control and cancer

artículo científico publicado en 2005

Contributions of nuclear architecture and chromatin to vitamin D-dependent transcriptional control of the rat osteocalcin gene.

artículo científico publicado en 2001

Crystal structure of the nuclear matrix targeting signal of the transcription factor acute myelogenous leukemia-1/polyoma enhancer-binding protein 2alphaB/core binding factor alpha2

artículo científico publicado en 1999

Definitive hematopoiesis requires Runx1 C-terminal-mediated subnuclear targeting and transactivation.

artículo científico publicado en 2009

Differential regulation of the two principal Runx2/Cbfa1 n-terminal isoforms in response to bone morphogenetic protein-2 during development of the osteoblast phenotype.

artículo científico publicado en 2001

Dlx3 transcriptional regulation of osteoblast differentiation: temporal recruitment of Msx2, Dlx3, and Dlx5 homeodomain proteins to chromatin of the osteocalcin gene.

artículo científico publicado en 2004

Dwarfism in homozygous Agc1CreERT mice is associated with decreased expression of aggrecan.

artículo científico publicado en 2017

Effect of sodium hypochlorite on human pulp cells: an in vitro study.

artículo científico publicado en 2011

Fidelity of Runx2 activity in breast cancer cells is required for the generation of metastases-associated osteolytic disease.

artículo científico publicado en 2004

Functional architecture of the nucleus: organizing the regulatory machinery for gene expression, replication and repair.

artículo científico publicado en 2003

Genetic and epigenetic regulation in nuclear microenvironments for biological control in cancer

scientific article published on August 2008

Heparanase inhibits osteoblastogenesis and shifts bone marrow progenitor cell fate in myeloma bone disease.

scientific article published on 27 July 2013

Heparanase promotes myeloma progression by inducing mesenchymal features and motility of myeloma cells

artículo científico publicado en 2016

Immunofluorescence analysis using epitope-tagged proteins: in vitro system

scientific article published on 01 January 2004

Impaired intranuclear trafficking of Runx2 (AML3/CBFA1) transcription factors in breast cancer cells inhibits osteolysis in vivo.

artículo científico publicado en 2005

In situ immunofluorescence analysis: analyzing RNA synthesis by 5-bromouridine-5'-triphosphate labeling

artículo científico publicado en 2004

In situ immunofluorescence analysis: immunofluorescence microscopy

scientific article published on 01 January 2004

In situ nuclear organization of regulatory machinery

artículo científico publicado en 2008

Insight into regulatory factor targeting to transcriptionally active subnuclear sites.

artículo científico publicado en 1999

Intranuclear Trafficking: Organization and Assembly of Regulatory Machinery for Combinatorial Biological Control

artículo científico publicado en 2004

Intranuclear organization of RUNX transcriptional regulatory machinery in biological control of skeletogenesis and cancer

artículo científico publicado en 2003

Intranuclear trafficking of transcription factors: Requirements for vitamin D-mediated biological control of gene expression.

artículo científico publicado en 2003

Intranuclear trafficking of transcription factors: implications for biological control.

artículo científico publicado en 2000

Leukemia-associated AML1/ETO (8;21) chromosomal translocation protein increases the cellular representation of PML bodies

artículo científico publicado en 2000

Loss of Runx2 in committed osteoblasts impairs postnatal skeletogenesis.

artículo científico publicado en 2015

MicroRNA 665 Regulates Dentinogenesis through MicroRNA-Mediated Silencing and Epigenetic Mechanisms

artículo científico publicado en 2015

Microtubule-dependent nuclear-cytoplasmic shuttling of Runx2.

artículo científico publicado en 2006

Mitotic occupancy and lineage-specific transcriptional control of rRNA genes by Runx2.

artículo científico publicado en 2007

Mitotic partitioning and selective reorganization of tissue-specific transcription factors in progeny cells

scientific journal article

Mitotic retention of gene expression patterns by the cell fate-determining transcription factor Runx2.

artículo científico publicado en 2007

Multiple Cbfa/AML sites in the rat osteocalcin promoter are required for basal and vitamin D-responsive transcription and contribute to chromatin organization.

artículo científico publicado en 1999

Myeloma cell-derived Runx2 promotes myeloma progression in bone.

artículo científico publicado en 2015

Networks and hubs for the transcriptional control of osteoblastogenesis.

artículo científico publicado en 2006

Nuclear microenvironments in biological control and cancer.

artículo científico publicado en 2007

Nuclear microenvironments support assembly and organization of the transcriptional regulatory machinery for cell proliferation and differentiation

artículo científico publicado en 2004

Nuclear microenvironments support physiological control of gene expression

artículo científico publicado en 2003

Organization of transcriptional regulatory machinery in nuclear microenvironments: implications for biological control and cancer

artículo científico publicado en 2007

Organization of transcriptional regulatory machinery in osteoclast nuclei: compartmentalization of Runx1.

artículo científico publicado en 2005

Organization, integration, and assembly of genetic and epigenetic regulatory machinery in nuclear microenvironments: implications for biological control in cancer

artículo científico publicado en 2009

Oxidative stress induces vascular calcification through modulation of the osteogenic transcription factor Runx2 by AKT signaling.

artículo científico publicado en 2008

Protein-deoxyribonucleic acid interactions linked to gene expression: DNase I digestion.

artículo científico publicado en 2004

Protein-deoxyribonucleic acid interactions linked to gene expression: electrophoretic mobility shift assay

scientific article published on 01 January 2004

Protein-deoxyribonucleic acid interactions linked to gene expression: ligation-mediated polymerase chain reaction

artículo científico publicado en 2004

Quantitative signature for architectural organization of regulatory factors using intranuclear informatics.

artículo científico publicado en 2004

Reconstitution of Runx2/Cbfa1-null cells identifies a requirement for BMP2 signaling through a Runx2 functional domain during osteoblast differentiation

artículo científico publicado en 2007

Regulation of the bone-specific osteocalcin gene by p300 requires Runx2/Cbfa1 and the vitamin D3 receptor but not p300 intrinsic histone acetyltransferase activity

scientific journal article

Regulatory controls for osteoblast growth and differentiation: role of Runx/Cbfa/AML factors

artículo científico publicado en 2004

Regulatory roles of Runx2 in metastatic tumor and cancer cell interactions with bone.

artículo científico publicado en 2006

Runx1/AML1 hematopoietic transcription factor contributes to skeletal development in vivo.

artículo científico publicado en 2003

Runx2 activity in committed osteoblasts is not essential for embryonic skeletogenesis.

artículo científico publicado en 2014

Runx2 control of organization, assembly and activity of the regulatory machinery for skeletal gene expression

artículo científico publicado en 2004

Runx2 regulates G protein-coupled signaling pathways to control growth of osteoblast progenitors

artículo científico publicado en 2008

Runx2 regulates endochondral ossification through control of chondrocyte proliferation and differentiation

artículo científico publicado en 2014

Runx2 regulates the gene network associated with insulin signaling and energy homeostasis

artículo científico publicado en 2011

Runx2/Cbfa1 functions: diverse regulation of gene transcription by chromatin remodeling and co-regulatory protein interactions

artículo científico publicado en 2003

SWI/SNF chromatin remodeling complex is obligatory for BMP2-induced, Runx2-dependent skeletal gene expression that controls osteoblast differentiation

scientific journal article

Smad function and intranuclear targeting share a Runx2 motif required for osteogenic lineage induction and BMP2 responsive transcription.

artículo científico publicado en 2005

Smooth muscle cell-specific runx2 deficiency inhibits vascular calcification.

artículo científico publicado en 2012

Sp7 and Runx2 molecular complex synergistically regulate expression of target genes

artículo científico publicado en 2014

Specific residues of RUNX2 are obligatory for formation of BMP2-induced RUNX2-SMAD complex to promote osteoblast differentiation.

artículo científico publicado en 2008

Specificity protein 7 is not essential for tooth morphogenesis.

artículo científico publicado en 2014

Structural coupling of Smad and Runx2 for execution of the BMP2 osteogenic signal.

artículo científico publicado en 2008

Subnuclear localization and intranuclear trafficking of transcription factors

artículo científico publicado en 2010

Subnuclear organization and trafficking of regulatory proteins: implications for biological control and cancer.

artículo científico publicado en 2000

Subnuclear targeting of Runx/Cbfa/AML factors is essential for tissue-specific differentiation during embryonic development

artículo científico publicado en 2001

Subnuclear targeting of Runx1 is required for synergistic activation of the myeloid specific M-CSF receptor promoter by PU.1.

artículo científico publicado en 2005

The Runx2 osteogenic transcription factor regulates matrix metalloproteinase 9 in bone metastatic cancer cells and controls cell invasion

artículo científico publicado en 2005

The dynamic organization of gene-regulatory machinery in nuclear microenvironments

artículo científico publicado en 2005

The vitamin D response element in the distal osteocalcin promoter contributes to chromatin organization of the proximal regulatory domain

artículo científico publicado en 2004

Transcription factors RUNX1/AML1 and RUNX2/Cbfa1 dynamically associate with stationary subnuclear domains.

artículo científico publicado en 2002

Transcription-factor-mediated epigenetic control of cell fate and lineage commitment

scientific article published on February 2009

Transcriptional Auto-Regulation of RUNX1 P1 Promoter

artículo científico publicado en 2016

Lista de obras de Amjad Javed

A Runx2 threshold for the cleidocranial dysplasia phenotype

Alterations in intranuclear localization of Runx2 affect biological activity

Altered chromatin modifications in AML1/RUNX1 breakpoint regions involved in (8;21) translocation.

Analysis of in vivo gene expression using epitope-tagged proteins

BMP2 commitment to the osteogenic lineage involves activation of Runx2 by DLX3 and a homeodomain transcriptional network.

Biphasic peptide amphiphile nanomatrix embedded with hydroxyapatite nanoparticles for stimulated osteoinductive response.

CBFa(AML/PEBP2)-related elements in the TGF-beta type I receptor promoter and expression with osteoblast differentiation

CCAAT/enhancer-binding proteins (C/EBP) beta and delta activate osteocalcin gene transcription and synergize with Runx2 at the C/EBP element to regulate bone-specific expression.

Canonical WNT Signaling Promotes Osteogenesis by Directly StimulatingRunx2Gene Expression

Cbfbeta interacts with Runx2 and has a critical role in bone development

Chondrocyte-specific regulatory activity of Runx2 is essential for survival and skeletal development

Chromatin immunoprecipitation

Chromatin immunoprecipitation assays: application of ChIP-on-chip for defining dynamic transcriptional mechanisms in bone cells.

Combinatorial organization of the transcriptional regulatory machinery in biological control and cancer

Contributions of nuclear architecture and chromatin to vitamin D-dependent transcriptional control of the rat osteocalcin gene.

Crystal structure of the nuclear matrix targeting signal of the transcription factor acute myelogenous leukemia-1/polyoma enhancer-binding protein 2alphaB/core binding factor alpha2

Definitive hematopoiesis requires Runx1 C-terminal-mediated subnuclear targeting and transactivation.

Differential regulation of the two principal Runx2/Cbfa1 n-terminal isoforms in response to bone morphogenetic protein-2 during development of the osteoblast phenotype.

Dlx3 transcriptional regulation of osteoblast differentiation: temporal recruitment of Msx2, Dlx3, and Dlx5 homeodomain proteins to chromatin of the osteocalcin gene.

Dwarfism in homozygous Agc1CreERT mice is associated with decreased expression of aggrecan.

Effect of sodium hypochlorite on human pulp cells: an in vitro study.

Fidelity of Runx2 activity in breast cancer cells is required for the generation of metastases-associated osteolytic disease.

Functional architecture of the nucleus: organizing the regulatory machinery for gene expression, replication and repair.

Genetic and epigenetic regulation in nuclear microenvironments for biological control in cancer

Heparanase inhibits osteoblastogenesis and shifts bone marrow progenitor cell fate in myeloma bone disease.

Heparanase promotes myeloma progression by inducing mesenchymal features and motility of myeloma cells

Immunofluorescence analysis using epitope-tagged proteins: in vitro system

Impaired intranuclear trafficking of Runx2 (AML3/CBFA1) transcription factors in breast cancer cells inhibits osteolysis in vivo.

In situ immunofluorescence analysis: analyzing RNA synthesis by 5-bromouridine-5'-triphosphate labeling

In situ immunofluorescence analysis: immunofluorescence microscopy

In situ nuclear organization of regulatory machinery

Insight into regulatory factor targeting to transcriptionally active subnuclear sites.

Intranuclear Trafficking: Organization and Assembly of Regulatory Machinery for Combinatorial Biological Control

Intranuclear organization of RUNX transcriptional regulatory machinery in biological control of skeletogenesis and cancer

Intranuclear trafficking of transcription factors: Requirements for vitamin D-mediated biological control of gene expression.

Intranuclear trafficking of transcription factors: implications for biological control.

Leukemia-associated AML1/ETO (8;21) chromosomal translocation protein increases the cellular representation of PML bodies

Loss of Runx2 in committed osteoblasts impairs postnatal skeletogenesis.

MicroRNA 665 Regulates Dentinogenesis through MicroRNA-Mediated Silencing and Epigenetic Mechanisms

Microtubule-dependent nuclear-cytoplasmic shuttling of Runx2.

Mitotic occupancy and lineage-specific transcriptional control of rRNA genes by Runx2.

Mitotic partitioning and selective reorganization of tissue-specific transcription factors in progeny cells

Mitotic retention of gene expression patterns by the cell fate-determining transcription factor Runx2.

Multiple Cbfa/AML sites in the rat osteocalcin promoter are required for basal and vitamin D-responsive transcription and contribute to chromatin organization.

Myeloma cell-derived Runx2 promotes myeloma progression in bone.

Networks and hubs for the transcriptional control of osteoblastogenesis.

Nuclear microenvironments in biological control and cancer.

Nuclear microenvironments support assembly and organization of the transcriptional regulatory machinery for cell proliferation and differentiation

Nuclear microenvironments support physiological control of gene expression

Organization of transcriptional regulatory machinery in nuclear microenvironments: implications for biological control and cancer

Organization of transcriptional regulatory machinery in osteoclast nuclei: compartmentalization of Runx1.

Organization, integration, and assembly of genetic and epigenetic regulatory machinery in nuclear microenvironments: implications for biological control in cancer

Oxidative stress induces vascular calcification through modulation of the osteogenic transcription factor Runx2 by AKT signaling.

Protein-deoxyribonucleic acid interactions linked to gene expression: DNase I digestion.

Protein-deoxyribonucleic acid interactions linked to gene expression: electrophoretic mobility shift assay

Protein-deoxyribonucleic acid interactions linked to gene expression: ligation-mediated polymerase chain reaction

Quantitative signature for architectural organization of regulatory factors using intranuclear informatics.

Reconstitution of Runx2/Cbfa1-null cells identifies a requirement for BMP2 signaling through a Runx2 functional domain during osteoblast differentiation

Regulation of the bone-specific osteocalcin gene by p300 requires Runx2/Cbfa1 and the vitamin D3 receptor but not p300 intrinsic histone acetyltransferase activity

Regulatory controls for osteoblast growth and differentiation: role of Runx/Cbfa/AML factors

Regulatory roles of Runx2 in metastatic tumor and cancer cell interactions with bone.

Runx1/AML1 hematopoietic transcription factor contributes to skeletal development in vivo.

Runx2 activity in committed osteoblasts is not essential for embryonic skeletogenesis.

Runx2 control of organization, assembly and activity of the regulatory machinery for skeletal gene expression

Runx2 regulates G protein-coupled signaling pathways to control growth of osteoblast progenitors

Runx2 regulates endochondral ossification through control of chondrocyte proliferation and differentiation

Runx2 regulates the gene network associated with insulin signaling and energy homeostasis

Runx2/Cbfa1 functions: diverse regulation of gene transcription by chromatin remodeling and co-regulatory protein interactions

SWI/SNF chromatin remodeling complex is obligatory for BMP2-induced, Runx2-dependent skeletal gene expression that controls osteoblast differentiation

Smad function and intranuclear targeting share a Runx2 motif required for osteogenic lineage induction and BMP2 responsive transcription.

Smooth muscle cell-specific runx2 deficiency inhibits vascular calcification.

Sp7 and Runx2 molecular complex synergistically regulate expression of target genes

Specific residues of RUNX2 are obligatory for formation of BMP2-induced RUNX2-SMAD complex to promote osteoblast differentiation.

Specificity protein 7 is not essential for tooth morphogenesis.

Structural coupling of Smad and Runx2 for execution of the BMP2 osteogenic signal.

Subnuclear localization and intranuclear trafficking of transcription factors

Subnuclear organization and trafficking of regulatory proteins: implications for biological control and cancer.

Subnuclear targeting of Runx/Cbfa/AML factors is essential for tissue-specific differentiation during embryonic development

Subnuclear targeting of Runx1 is required for synergistic activation of the myeloid specific M-CSF receptor promoter by PU.1.