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Lista de obras de Charles Craddock

A comparative assessment of the curative potential of reduced intensity allografts in acute myeloid leukaemia

scientific article published on 07 November 2014

A comparison between allogeneic stem cell transplantation from unmanipulated haploidentical and unrelated donors in acute leukemia.

artículo científico publicado en 2017

A comparison of prophylactic vs pre-emptive ganciclovir to prevent cytomegalovirus disease after T-depleted volunteer unrelated donor bone marrow transplantation

artículo científico publicado en 1999

ABO incompatibility in mismatched unrelated donor allogeneic hematopoietic cell transplantation for acute myeloid leukemia: A report from the acute leukemia working party of the EBMT.

artículo científico publicado en 2017

Acquired isodisomy for chromosome 13 is common in AML, and associated with FLT3-itd mutations

artículo científico publicado en 2005

Acquired isodisomy on chromosome 13 at diagnosis results in impaired overall survival in patients with FLT3-ITD mutant acute myeloid leukaemia.

artículo científico publicado en 2015

Acute myeloid leukaemia therapeutic innovation and clinical trials: past, present and future

artículo científico publicado en 2020

Adoptive transfer of cytomegalovirus-specific CTL to stem cell transplant patients after selection by HLA-peptide tetramers

artículo científico publicado en 2005

Allogeneic Stem Cell Transplantation for Myelodysplastic Syndrome Patients with a 5q Deletion.

artículo científico publicado en 2017

Allogeneic haematopoietic stem cell transplant in patients with lower risk myelodysplastic syndrome: a retrospective analysis on behalf of the Chronic Malignancy Working Party of the EBMT.

artículo científico publicado en 2016

Allogeneic hematopoietic cell transplantation for acute myeloid leukemia

artículo científico publicado en 2014

Allogeneic stem cell transplantation benefits for patients ≥ 60 years with acute myeloid leukemia and FLT3 internal tandem duplication: a study from the Acute Leukemia Working Party of the European Society for Blood and Marrow Transplantation

artículo científico publicado en 2017

Allogeneic stem cell transplantation in patients with atypical chronic myeloid leukaemia: a retrospective study from the Chronic Malignancies Working Party of the European Society for Blood and Marrow Transplantation

artículo científico publicado en 2017

Allogeneic transplantation in primary refractory AML

scientific article published on 24 April 2017

Alternative donors for allogeneic hematopoietic stem cell transplantation in poor-risk AML in CR1

artículo científico publicado en 2017

An operational definition of primary refractory acute myeloid leukemia allowing early identification of patients who may benefit from allogeneic stem cell transplantation

artículo científico publicado en 2016

Antilymphocyte Globulin for matched sibling donor transplantation in patients with myelofibrosis

scientific article published on 17 January 2019

Association of Macroeconomic Factors With Nonrelapse Mortality After Allogeneic Hematopoietic Cell Transplantation for Adults With Acute Lymphoblastic Leukemia: An Analysis From the Acute Leukemia Working Party of the EBMT.

artículo científico publicado en 2016

Autologous stem cell transplantation for enteropathy-associated T-cell lymphoma: a retrospective study by the EBMT.

artículo científico publicado en 2013

Azacitidine augments expansion of regulatory T cells after allogeneic stem cell transplantation in patients with acute myeloid leukemia (AML)

artículo científico publicado en 2012

Azacitidine fails to eradicate leukemic stem/progenitor cell populations in patients with acute myeloid leukemia and myelodysplasia

artículo científico publicado en 2012

BEAM-alemtuzumab reduced-intensity allogeneic stem cell transplantation for lymphoproliferative diseases: GVHD, toxicity, and survival in 65 patients.

artículo científico publicado en 2003

Biology and management of relapsed acute myeloid leukaemia.

artículo científico publicado en 2005

Bone marrow transplantation in the United Kingdom - past, present and future

artículo científico publicado en 2020

Bortezomib, low-dose intravenous melphalan, and dexamethasone for patients with relapsed multiple myeloma

artículo científico publicado en 2009

CC-486 Maintenance after Stem Cell Transplantation in Patients with Acute Myeloid Leukemia or Myelodysplastic Syndromes

artículo científico publicado en 2018

CD8(+) T-cell immunity against cancer-testis antigens develops following allogeneic stem cell transplantation and reveals a potential mechanism for the graft-versus-leukemia effect.

artículo científico publicado en 2010

CXCL10-CXCR3 interactions play an important role in the pathogenesis of acute graft-versus-host disease in the skin following allogeneic stem-cell transplantation.

artículo científico publicado en 2007

Characterization of CMV-specific CD4+ T-cell reconstitution following stem cell transplantation through the use of HLA Class II-peptide tetramers identifies patients at high risk of recurrent CMV reactivation.

artículo científico publicado en 2015

Chemokine-mediated tissue recruitment of CXCR3+ CD4+ T cells plays a major role in the pathogenesis of chronic GVHD

artículo científico publicado en 2012

Chromosomal stabilisation by a subtelomeric rearrangement involving two closely related Alu elements

artículo científico publicado en 1996

Chronic graft-versus-host disease is associated with increased numbers of peripheral blood CD4+CD25high regulatory T cells

artículo científico publicado en 2003

Clinical activity of azacitidine in patients who relapse after allogeneic stem cell transplantation for acute myeloid leukemia.

artículo científico publicado en 2016

Clinical evaluation of treatment with ciprofloxacin

artículo científico publicado en 1986

Clinical evidence of a graft-versus-Hodgkin's-lymphoma effect after reduced-intensity allogeneic transplantation

artículo científico publicado en 2005

Coexistence of LMPP-like and GMP-like Leukemia Stem Cells in Acute Myeloid Leukemia

scientific article published on 01 January 2011

Combination Lenalidomide and Azacitidine: A Novel Salvage Therapy in Patients Who Relapse After Allogeneic Stem-Cell Transplantation for Acute Myeloid Leukemia

artículo científico publicado en 2019

Comparable outcomes of haploidentical, 10/10 and 9/10 unrelated donor transplantation in adverse karyotype AML in first complete remission

artículo científico publicado en 2018

Comparison of Intensive Chemotherapy and Hypomethylating Agents before Allogeneic Stem Cell Transplantation for Advanced Myelodysplastic Syndromes: A Study of the Myelodysplastic Syndrome Subcommittee of the Chronic Malignancies Working Party of the

artículo científico publicado en 2016

Comparison of unrelated cord blood and peripheral blood stem cell transplantation in adults with myelodysplastic syndrome after reduced-intensity conditioning regimen: a collaborative study from Eurocord (Cord blood Committee of Cellular Therapy & I

artículo científico publicado en 2014

Conditioning intensity in HCT for AML: the jury is still out

scientific article published on 14 March 2018

Cord Blood Unit Dominance Analysis and Effect of the Winning Unit on Outcomes after Double-Unit Umbilical Cord Blood Transplantation in Adults with Acute Leukemia: A Retrospective Study on Behalf of Eurocord, the Cord Blood Committee of Cellular The

artículo científico publicado en 2018

Cross-intolerance to imatinib, dasatinib and nilotinib therapy in a patient with chronic myeloid leukaemia

artículo científico publicado en 2011

Cryopreservation of allogeneic PBSC from related and unrelated donors is associated with delayed platelet engraftment but has no impact on survival.

artículo científico publicado en 2012

Cytomegalovirus seropositivity adversely influences outcome after T-depleted unrelated donor transplant in patients with chronic myeloid leukaemia: the case for tailored graft-versus-host disease prophylaxis

artículo científico publicado en 2001

Distinct factors determine the kinetics of disease relapse in adults transplanted for acute myeloid leukaemia.

artículo científico publicado en 2017

Donor KIR genotype has a major influence on the rate of cytomegalovirus reactivation following T-cell replete stem cell transplantation

artículo científico publicado en 2005

Dose Transition Pathways: The Missing Link Between Complex Dose-Finding Designs and Simple Decision-Making

artículo científico publicado en 2017

EBV-associated post-transplant lymphoproliferative disorder following in vivo T-cell-depleted allogeneic transplantation: clinical features, viral load correlates and prognostic factors in the rituximab era.

artículo científico publicado en 2013

Early detection of BCR-ABL transcripts by quantitative reverse transcriptase-polymerase chain reaction predicts outcome after allogeneic stem cell transplantation for chronic myeloid leukemia

scientific article published on 01 March 2001

Embracing model-based designs for dose-finding trials. ⬇️

artículo científico publicado en 2017

Enshrining donor rights and optimizing patient outcome in unrelated donor transplantation

artículo científico publicado en 2010

Epigenetic manipulation of the immune response: a novel treatment strategy in hematologic malignancies ⬇️

artículo científico publicado el 7 de marzo de 2011

Estimation of current leukaemia-free survival following donor lymphocyte infusion therapy for patients with leukaemia who relapse after allografting: application of a multistate model

scientific article published on 01 November 2000

Evidence for a GVL effect following reduced-intensity allo-SCT in ALL: a British Society of Blood and Marrow Transplantation study ⬇️

artículo científico publicado el 14 de enero de 2013

Evidence for different mechanisms of 'unhooking' for melphalan and cisplatin-induced DNA interstrand cross-links in vitro and in clinical acquired resistant tumour samples.

artículo científico publicado en 2012

Exacerbation of IgA nephropathy following G-CSF administration for PBSC collection: suggestions for better donor screening

artículo científico publicado en 2015

Expanding transplant options to patients over 50 years. Improved outcome after reduced intensity conditioning mismatched-unrelated donor transplantation for patients with acute myeloid leukemia: a report from the Acute Leukemia Working Party of the

artículo científico publicado en 2016

Facial flushing and localized Castleman's disease: an extension of the POEMS syndrome phenotype

artículo científico publicado en 2003

Factors predicting long-term survival after T-cell depleted reduced intensity allogeneic stem cell transplantation for acute myeloid leukemia

artículo científico publicado en 2009

Factors predicting outcome after unrelated donor stem cell transplantation in primary refractory acute myeloid leukaemia

artículo científico publicado en 2011

Fasting: starving cancer

artículo científico publicado en 2017

Favorable outcomes with alemtuzumab-conditioned unrelated donor stem cell transplantation in adults with high-risk Philadelphia chromosome-negative acute lymphoblastic leukemia in first complete remission

artículo científico publicado en 2009

Frequent epigenetic inactivation of KIBRA, an upstream member of the Salvador/Warts/Hippo (SWH) tumor suppressor network, is associated with specific genetic event in B-cell acute lymphocytic leukemia.

artículo científico publicado en 2011

Genetically distinct leukemic stem cells in human CD34- acute myeloid leukemia are arrested at a hemopoietic precursor-like stage.

artículo científico publicado en 2016

Greatly reduced risk of EBV reactivation in rituximab-experienced recipients of alemtuzumab-conditioned allogeneic HSCT. ⬇️

artículo científico publicado en 2016

Guidelines for the diagnosis and management of acute myeloid leukaemia in pregnancy

artículo científico publicado en 2015

High incidence of cytomegalovirus infection after nonmyeloablative stem cell transplantation: potential role of Campath-1H in delaying immune reconstitution

scientific article published on 01 June 2002

High-dose busulphan alone as cytoreduction before allogeneic or autologous stem cell transplantation for chronic myeloid leukaemia: a single-centre experience

artículo científico publicado en 2000

High-dose etoposide with granulocyte colony-stimulating factor for mobilization of peripheral blood progenitor cells: efficacy and toxicity at three dose levels ⬇️

artículo científico publicado el 1 de octubre de 1998

High-hyperdiploidy in Philadelphia positive adult acute lymphoblastic leukaemia: case-series and review of literature.

artículo científico publicado en 2003

Histone deacetylases in acute myeloid leukaemia show a distinctive pattern of expression that changes selectively in response to deacetylase inhibitors.

artículo científico publicado en 2005

Imatinib mesylate (STI571) in the treatment of relapse of chronic myeloid leukemia after allogeneic stem cell transplantation

artículo científico publicado en 2002

Imatinib or transplant for chronic myeloid leukaemia?

artículo científico publicado en 2003

Immune haemolytic anaemia following T cell-depleted allogeneic bone marrow transplantation for chronic myeloid leukaemia: association with leukaemic relapse and treatment with donor lymphocyte infusions.

artículo científico publicado en 2001

Impact of Alemtuzumab Scheduling on Graft-versus-Host Disease after Unrelated Donor Fludarabine and Melphalan Allografts

artículo científico publicado en 2017

Impact of in vivo T-cell depletion on outcome of AML patients in first CR given peripheral blood stem cells and reduced-intensity conditioning allo-SCT from a HLA-identical sibling donor: a report from the Acute Leukemia Working Party of the Europea

artículo científico publicado en 2014

Impact of patient: donor HLA disparity on reduced-intensity-conditioned allogeneic stem cell transplants from HLA mismatched unrelated donors for AML: from the ALWP of the EBMT

scientific article published on 02 October 2020

Improving Outcomes in High-Risk Myelodysplasia: Festina Lente

artículo científico publicado en 2017

Incidence, Risk Factors and Long-Term Outcome of Acute Leukemia Patients with Early Candidemia after Allogeneic Stem Cell Transplantation. A Study by the Acute Leukemia and Infectious Diseases Working Parties of EBMT.

artículo científico publicado en 2018

Increased acute GvHD and higher transplant-related mortality in non-caucasians undergoing standard sibling allogeneic stem cell transplantation

artículo científico publicado en 2006

Increases in airway responsiveness to histamine precede allergen-induced late asthmatic responses

artículo científico publicado en 1988

Induction of a CD8+ T-cell response to the MAGE cancer testis antigen by combined treatment with azacitidine and sodium valproate in patients with acute myeloid leukemia and myelodysplasia

artículo científico publicado en 2010

Influence of pre-existing invasive aspergillosis on allo-HSCT outcome: a retrospective EBMT analysis by the Infectious Diseases and Acute Leukemia Working Parties

artículo científico publicado en 2015

Integrating pharmacogenetics and therapeutic drug monitoring: optimal dosing of imatinib as a case-example.

scientific article published on 29 January 2010

Limiting transplantation-related mortality following unrelated donor stem cell transplantation by using a nonmyeloablative conditioning regimen

artículo científico publicado en 2002

MHC class I-associated phosphopeptides are the targets of memory-like immunity in leukemia.

artículo científico publicado en 2013

Matched and mismatched unrelated donor compared to autologous stem cell transplantation for acute myeloid leukemia in first complete remission: a retrospective, propensity score-weighted analysis from the ALWP of the EBMT

artículo científico publicado en 2016

Matched unrelated donor allogeneic transplantation provides comparable long-term outcome to HLA-identical sibling transplantation in relapsed diffuse large B-cell lymphoma.

artículo científico publicado en 2014

Memory B-cell reconstitution following allogeneic hematopoietic stem cell transplantation is an EBV-associated transformation event

artículo científico publicado en 2015

Molecular studies in patients with chronic myeloid leukaemia in remission 5 years after allogeneic stem cell transplant define the risk of subsequent relapse

article

Molecularly targeted therapy in myeloid leukaemias.

artículo científico publicado en 2007

Mutational analysis of disease relapse in patients allografted for acute myeloid leukemia

artículo científico publicado en 2016

Mylotarg has potent anti-leukaemic effect: a systematic review and meta-analysis of anti-CD33 antibody treatment in acute myeloid leukaemia.

artículo científico

NK cells produce high levels of IL-10 early after allogeneic stem cell transplantation and suppress development of acute GVHD.

artículo científico publicado en 2017

Origin and subset distribution of peripheral blood dendritic cells in patients with chronic graft-versus-host disease1

artículo científico publicado en 2003

Outcome of Azacitidine Therapy in Acute Myeloid Leukemia Is not Improved by Concurrent Vorinostat Therapy but Is Predicted by a Diagnostic Molecular Signature.

artículo científico publicado en 2017

Outcome of second allogeneic transplants using reduced-intensity conditioning following relapse of haematological malignancy after an initial allogeneic transplant.

artículo científico publicado en 2008

Outcomes following 50 mg versus 100 mg alemtuzumab in reduced-intensity conditioning stem cell transplants for acute myeloid leukaemia and poor risk myelodysplasia

artículo científico publicado en 2008

Pertussis: should we vaccinate post transplant?

scientific article published on 01 April 2006

Post-transplant T cell chimerism predicts graft versus host disease but not disease relapse in patients undergoing an alemtuzumab based reduced intensity conditioned allogeneic transplant

artículo científico publicado en 2013

Posttransplantation imatinib as a strategy to postpone the requirement for immunotherapy in patients undergoing reduced-intensity allografts for chronic myeloid leukemia

artículo científico publicado en 2007

Prediction of Allogeneic Hematopoietic Stem-Cell Transplantation Mortality 100 Days After Transplantation Using a Machine Learning Algorithm: A European Group for Blood and Marrow Transplantation Acute Leukemia Working Party Retrospective Data [...]

artículo científico publicado en 2015

Professor David Grimwade (1962-2016)

scientific article published on 16 January 2017

Prognostic value of monitoring a candidate immunophenotypic leukaemic stem/progenitor cell population in patients allografted for acute myeloid leukaemia

artículo científico publicado en 2014

Realising the potential of targeted therapies in oncology

artículo científico publicado en 2002

Recommendations for a standard UK approach to incorporating umbilical cord blood into clinical transplantation practice: an update on cord blood unit selection, donor selection algorithms and conditioning protocols.

artículo científico publicado en 2015

Recommendations for a standard UK approach to incorporating umbilical cord blood into clinical transplantation practice: conditioning protocols and donor selection algorithms.

artículo científico publicado en 2009

Reduced CD38 expression on CD34+ cells as a diagnostic test in myelodysplastic syndromes

artículo científico publicado en 2009

Repair of DNA interstrand crosslinks as a mechanism of clinical resistance to melphalan in multiple myeloma.

artículo científico publicado en 2002

Reprint of: Allogeneic hematopoietic cell transplantation for acute myeloid leukemia

artículo científico publicado en 2015

Rituximab is effective in the management of refractory autoimmune cytopenias occurring after allogeneic stem cell transplantation.

artículo científico publicado en 2005

Role of HCT-comorbidity index, age and disease status at transplantation in predicting survival and non-relapse mortality in patients with myelodysplasia and leukemia undergoing reduced-intensity-conditioning hemopoeitic progenitor cell transplantat

artículo científico publicado en 2011

Role of Nonmyeloablative Allogeneic Stem-Cell Transplantation After Failure of Autologous Transplantation in Patients With Lymphoproliferative Malignancies

artículo científico publicado en 2002

Secondary anchor polymorphism in the HA-1 minor histocompatibility antigen critically affects MHC stability and TCR recognition.

artículo científico publicado en 2009

Sp1 functions in a chromatin-dependent manner to augment human alpha-globin promoter activity ⬇️

artículo científico publicado el 1 de agosto de 1995

Stem cell transplantation after salvage therapy with high-dose cytarabine and amsacrine in adults with high-risk leukaemia.

artículo científico publicado en 2003

Stratified medicine in European Medicines Agency licensing: a systematic review of predictive biomarkers

artículo científico publicado en 2014

Stratified medicine in practice: review of predictive biomarkers in European Medicines Agency (EMA) indications.

artículo científico publicado en 2011

Subsequent donation requests among 2472 unrelated hematopoietic progenitor cell donors are associated with bone marrow harvest ⬇️

artículo científico publicado el 28 de junio de 2013

Successful use of Campath-1H in the treatment of steroid refractory liver GvHD.

artículo científico publicado en 2004

Survival after bone-marrow transplantation

artículo científico publicado en 2002

T-cell depletion does not necessarily compromise donor stem cell engraftment in patients receiving reduced-intensity conditioning regimens

scientific article published on 01 June 2003

Targeting the arginine metabolic brake enhances immunotherapy for leukaemia

scientific article published on 11 January 2019

The number of CD56dim NK cells in the graft has a major impact on risk of disease relapse following allo-HSCT

scientific article published on 21 August 2017

The role of CS1 moiety of fibronectin in VLA mediated haemopoietic progenitor trafficking

artículo científico publicado en 1997

The role of allogeneic SCT in primary myelofibrosis: a British Society for Blood and Marrow Transplantation study.

artículo científico publicado en 2010

The role of allogeneic stem cell transplantation in the management of acute myeloid leukaemia: a triumph of hope and experience

artículo científico publicado en 2019

The use of a national transplant registry to benchmark transplant outcome for patients undergoing autologous and allogeneic stem cell transplantation in the United Kingdom and Ireland

artículo científico publicado en 2004

Tolerability and Clinical Activity of Post-Transplantation Azacitidine in Patients Allografted for Acute Myeloid Leukemia Treated on the RICAZA Trial

artículo científico publicado en 2015

Topical issues in unrelated donor haematopoietic stem cell transplants: a report from a workshop convened by the Anthony Nolan Trust in London - 2005.

artículo científico publicado en 2006

Treatment of relapse after allogeneic bone marrow transplantation with reduced intensity conditioning (FLAG +/- Ida) and second allogeneic stem cell transplant.

artículo científico publicado en 2001

Tyrosine kinase inhibitors improve long-term outcome of allogeneic hematopoietic stem cell transplantation for adult patients with Philadelphia chromosome positive acute lymphoblastic leukemia

artículo científico publicado en 2014

Unique features and clinical importance of acute alloreactive immune responses.

artículo científico publicado en 2018

Unrelated Cord Blood Transplantation in adults: evolution, experience and long-term outcomes in the UK National Health Service : a retrospective analysis on behalf of the British Society of Blood and Marrow Transplantation and Eurocord

artículo científico publicado en 2015

Unrelated donor peripheral blood stem cell transplants incorporating pre-transplant in-vivo alemtuzumab are not associated with any increased risk of significant acute or chronic graft-versus-host disease.

artículo científico publicado en 2011

Who is the best hematopoietic stem-cell donor for a male patient with acute leukemia?

artículo científico publicado en 2014

Wilms' Tumour 1 (WT1) peptide vaccination in patients with acute myeloid leukaemia induces short-lived WT1-specific immune responses

artículo científico publicado en 2013

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