Lista de obras - Karen Bush - Dominio Público Uruguay

15-amido erythromycins: synthesis and in vitro activity of a new class of macrolide antibiotics

artículo científico publicado en 2005

7-(4-Alkylidenylpiperidinyl)-quinolone bacterial topoisomerase inhibitors

scientific article published on 12 October 2014

A Meandering Path from Biochemist to Microbiologist

artículo científico publicado en 2018

A MurF inhibitor that disrupts cell wall biosynthesis in Escherichia coli

artículo científico publicado en 2007

A Standard Numbering Scheme for Class C β-Lactamases

scientific article published on 21 February 2020

A point mutation in influenza B neuraminidase confers resistance to peramivir and loss of slow binding

artículo científico publicado en 2003

A randomized, double-blind trial comparing ceftobiprole medocaril with vancomycin plus ceftazidime for the treatment of patients with complicated skin and skin-structure infections

artículo científico publicado en 2008

Activities of ceftobiprole and other beta-lactams against Streptococcus pneumoniae clinical isolates from the United States with defined substitutions in penicillin-binding proteins PBP 1a, PBP 2b, and PBP 2x.

artículo científico publicado en 2006

Activity of doripenem and comparator beta-lactams against US clinical isolates of Streptococcus pneumoniae with defined mutations in the penicillin-binding domains of pbp1a, pbp2b and pbp2x

artículo científico publicado en 2008

Activity of imipenem/relebactam against carbapenemase-producing Enterobacteriaceae with high colistin resistance

artículo científico publicado en 2019

Affinity of ceftobiprole for penicillin-binding protein 2b in Streptococcus pneumoniae strains with various susceptibilities to penicillin

artículo científico publicado en 2010

Affinity of doripenem and comparators to penicillin-binding proteins in Escherichia coli and Pseudomonas aeruginosa

artículo científico publicado en 2008

Anti-MRSA beta-lactams in development, with a focus on ceftobiprole: the first anti-MRSA beta-lactam to demonstrate clinical efficacy

artículo científico publicado en 2007

Antibacterial activity of pyrrolopyridine-substituted oxazolidinones: synthesis and in vitro SAR of various C-5 acetamide replacements

artículo científico publicado en 2006

Author Correction: Interplay between β-lactamases and new β-lactamase inhibitors

artículo científico publicado en 2019

Binding of ceftobiprole and comparators to the penicillin-binding proteins of Escherichia coli, Pseudomonas aeruginosa, Staphylococcus aureus, and Streptococcus pneumoniae

artículo científico publicado en 2007

Biochemical characterization of beta-lactamases Bla1 and Bla2 from Bacillus anthracis

artículo científico publicado en 2003

CAU-1, a subclass B3 metallo-beta-lactamase of low substrate affinity encoded by an ortholog present in the Caulobacter crescentus chromosome.

artículo científico publicado en 2002

Carbapenem-resistant strain of Klebsiella oxytoca harboring carbapenem-hydrolyzing beta-lactamase KPC-2.

artículo científico publicado en 2003

Cathelicidin Antimicrobial Peptides with Reduced Activation of Toll-Like Receptor Signaling Have Potent Bactericidal Activity against Colistin-Resistant Bacteria

scientific article published on 20 September 2016

Characterisation of Staphylococcus aureus and Enterococcus faecalis mutants with reduced susceptibility to the investigational oxazolidinone RWJ-416457 ⬇️

artículo científico publicado el 17 de septiembre de 2010

Characterization and dynamics of middle ear fluid and nasopharyngeal isolates of Streptococcus pneumoniae from 12 children treated with levofloxacin

artículo científico publicado en 2007

Comment on: Redefining extended-spectrum -lactamases: balancing science and clinical need

scientific article published on 24 March 2009

Comment on: Resistance gene naming and numbering: is it a new gene or not?

artículo científico publicado en 2016

Critical analysis of antibacterial agents in clinical development

artículo científico publicado en 2020

Cross-resistance, relatedness and allele analysis of fluoroquinolone-resistant US clinical isolates of Streptococcus pneumoniae (1998-2000).

artículo científico publicado en 2003

Detection systems for carbapenemase gene identification should include the SME serine carbapenemase

artículo científico publicado en 2012

Differential selection of single-step AmpC or efflux mutants of Pseudomonas aeruginosa by using cefepime, ceftazidime, or ceftobiprole

artículo científico publicado en 2010

Effect of MexXY overexpression on ceftobiprole susceptibility in Pseudomonas aeruginosa

artículo científico publicado en 2009

Effects of ceftobiprole and oxacillin on mecA expression in methicillin-resistant Staphylococcus aureus clinical isolates

artículo científico publicado en 2009

Effects of inoculum and beta-lactamase activity in AmpC- and extended-spectrum beta-lactamase (ESBL)-producing Escherichia coli and Klebsiella pneumoniae clinical isolates tested by using NCCLS ESBL methodology ⬇️

artículo científico publicado en 2004

Effects of the 7-valent pneumococcal conjugate vaccine on U.S. levofloxacin-resistant Streptococcus pneumoniae

artículo científico publicado en 2008

Epidemiology and risk factors for isolation of Escherichia coli producing CTX-M-type extended-spectrum β-lactamase in a large U.S. Medical Center.

artículo científico publicado en 2013

Epidemiology of β-Lactamase-Producing Pathogens

artículo científico publicado en 2020

Forgotten antibiotics: an inventory in Europe, the United States, Canada, and Australia

artículo científico publicado en 2012

Game Changers: New β-Lactamase Inhibitor Combinations Targeting Antibiotic Resistance in Gram-Negative Bacteria

artículo científico publicado en 2017

Hydrolysis and inhibition profiles of beta-lactamases from molecular classes A to D with doripenem, imipenem, and meropenem

artículo científico publicado en 2009

Identification of a dithiazoline inhibitor of Escherichia coli L,D-carboxypeptidase A

artículo científico publicado en 2005

In memoriam: John P. Quinn, MD.

artículo científico publicado en 2013

In vitro activities of novel 2-fluoro-naphthyridine-containing ketolides

artículo científico publicado en 2005

In vitro activity of ceftolozane-tazobactam as determined by broth dilution and agar diffusion assays against recent U.S. Escherichia coli isolates from 2010 to 2011 carrying CTX-M-type extended-spectrum β-lactamases

artículo científico publicado en 2014

In vitro activity of plazomicin against β-lactamase-producing carbapenem-resistant Enterobacteriaceae (CRE).

artículo científico publicado en 2017

In vitro antibacterial activities of JNJ-Q2, a new broad-spectrum fluoroquinolone

artículo científico publicado en 2010

In vitro antibacterial activity of the pyrrolopyrazolyl-substituted oxazolidinone RWJ-416457.

artículo científico publicado en 2006

In vitro susceptibility of characterized β-lactamase-producing strains tested with avibactam combinations.

artículo científico publicado en 2014

In vitro susceptibility of β-lactamase-producing carbapenem-resistant Enterobacteriaceae (CRE) to eravacycline.

artículo científico publicado en 2016

In vivo activity of ceftobiprole in murine skin infections due to Staphylococcus aureus and Pseudomonas aeruginosa

artículo científico publicado en 2009

In vivo activity of the pyrrolopyrazolyl-substituted oxazolidinone RWJ-416457.

artículo científico publicado en 2009

Infrequent occurrence of single mutations in topoisomerase IV and DNA gyrase genes among US levofloxacin-susceptible clinical isolates of Streptococcus pneumoniae from nine institutions (1999-2003).

artículo científico publicado en 2006

Interactions of ceftobiprole with beta-lactamases from molecular classes A to D.

artículo científico publicado en 2007

Interplay between β-lactamases and new β-lactamase inhibitors

artículo científico publicado en 2019

Investigational antimicrobial agents of 2013.

artículo científico publicado en 2013

Is it necessary to change the classification of {beta}-lactamases?

scientific article published on 10 May 2005

Molecular Correlation for the Treatment Outcomes in Bloodstream Infections Caused byEscherichia coliandKlebsiella pneumoniaewith Reduced Susceptibility to Ceftazidime ⬇️

artículo científico publicado el 4 de diciembre de 2001

MurF inhibitors with antibacterial activity: effect on muropeptide levels

artículo científico publicado en 2009

Novel Carbapenem-Hydrolyzing β-Lactamase, KPC-1, from a Carbapenem-Resistant Strain of Klebsiella pneumoniae.

artículo científico publicado en 2008

Novel antibacterial agents for the treatment of serious Gram-positive infections

artículo científico publicado en 2003

Novel piperidinyloxy oxazolidinone antibacterial agents. Diversification of the N-Substituent

artículo científico publicado en 2002

Past and Present Perspectives on β-Lactamases

scientific article published on 24 September 2018

Predominance of 23S rRNA mutants among non-erm, non-mef macrolide-resistant clinical isolates of Streptococcus pneumoniae collected in the United States in 1999-2000.

artículo científico publicado en 2005

Preparation of erythromycin analogs having functional groups at C-15.

artículo científico publicado en 2006

Prevalence of Single Mutations in Topoisomerase Type II Genes among Levofloxacin-Susceptible Clinical Strains of Streptococcus pneumoniae Isolated in the United States in 1992 to 1996 and 1999 to 2000 ⬇️

artículo científico publicado el 1 de enero de 2002

Publisher Correction: Interplay between β-lactamases and new β-lactamase inhibitors

scientific article published on 01 July 2019

Reply to Furlan et al., "Importance of Sequencing To Determine Functional blaTEM Variants".

artículo científico publicado en 2017

SME-3, a novel member of the Serratia marcescens SME family of carbapenem-hydrolyzing beta-lactamases

artículo científico publicado en 2006

Selection of hyperproduction of AmpC and SME-1 in a carbapenem-resistant Serratia marcescens isolate during antibiotic therapy

artículo científico publicado en 2018

Synthesis and antibacterial activity of 3-O-acyl-6-O-carbamoyl erythromycin A derivatives

artículo científico publicado en 2005

Synthesis and antibacterial activity of 3-keto-6-O-carbamoyl-11,12-cyclic thiocarbamate erythromycin A derivatives

artículo científico publicado en 2007

Synthesis and antibacterial activity of 6-O-heteroarylcarbamoyl-11,12-lactoketolides

artículo científico publicado en 2006

Synthesis and antibacterial activity of 7-(1,2,3,4-tetrahydropyrrolo[1,2-a]pyrazin-7-yl) quinolones.

artículo científico publicado en 2009

Synthesis and antibacterial activity of C-6 carbamate ketolides, a novel series of orally active ketolide antibiotics

artículo científico publicado en 2004

Synthesis and antibacterial activity of C2-fluoro, C6-carbamate ketolides, and their C9-oximes

artículo científico publicado en 2005

Synthesis and antibacterial activity of C6-carbazate ketolides

artículo científico publicado en 2006

Synthesis and antibacterial activity of pyrroloaryl-substituted oxazolidinones

artículo científico publicado en 2003

TEM-71, a novel plasmid-encoded, extended-spectrum beta-lactamase produced by a clinical isolate of Klebsiella pneumoniae

artículo científico publicado en 2002

Tackling antibiotic resistance

artículo científico publicado en 2011

The Curious Case of TEM-116.

artículo científico publicado en 2016

The synthesis and antimicrobial evaluation of a new series of isoxazolinyl oxazolidinones

artículo científico publicado en 2004

Unusual Escherichia coli PBP 3 Insertion Sequence Identified from a Collection of Carbapenem-Resistant Enterobacteriaceae Tested In Vitro with a Combination of Ceftazidime-, Ceftaroline-, or Aztreonam-Avibactam

artículo científico publicado en 2017

Updated functional classification of beta-lactamases

artículo científico publicado en 2010

Utility of muropeptide ligase for identification of inhibitors of the cell wall biosynthesis enzyme MurF.

artículo científico publicado en 2006

β-Lactams and β-Lactamase Inhibitors: An Overview

artículo científico publicado en 2016

Lista de obras de Karen Bush

15-amido erythromycins: synthesis and in vitro activity of a new class of macrolide antibiotics

7-(4-Alkylidenylpiperidinyl)-quinolone bacterial topoisomerase inhibitors

A Meandering Path from Biochemist to Microbiologist

A MurF inhibitor that disrupts cell wall biosynthesis in Escherichia coli

A Standard Numbering Scheme for Class C β-Lactamases

A point mutation in influenza B neuraminidase confers resistance to peramivir and loss of slow binding

A randomized, double-blind trial comparing ceftobiprole medocaril with vancomycin plus ceftazidime for the treatment of patients with complicated skin and skin-structure infections

Activities of ceftobiprole and other beta-lactams against Streptococcus pneumoniae clinical isolates from the United States with defined substitutions in penicillin-binding proteins PBP 1a, PBP 2b, and PBP 2x.

Activity of doripenem and comparator beta-lactams against US clinical isolates of Streptococcus pneumoniae with defined mutations in the penicillin-binding domains of pbp1a, pbp2b and pbp2x

Activity of imipenem/relebactam against carbapenemase-producing Enterobacteriaceae with high colistin resistance

Affinity of ceftobiprole for penicillin-binding protein 2b in Streptococcus pneumoniae strains with various susceptibilities to penicillin

Affinity of doripenem and comparators to penicillin-binding proteins in Escherichia coli and Pseudomonas aeruginosa

Anti-MRSA beta-lactams in development, with a focus on ceftobiprole: the first anti-MRSA beta-lactam to demonstrate clinical efficacy

Antibacterial activity of pyrrolopyridine-substituted oxazolidinones: synthesis and in vitro SAR of various C-5 acetamide replacements

Author Correction: Interplay between β-lactamases and new β-lactamase inhibitors

Binding of ceftobiprole and comparators to the penicillin-binding proteins of Escherichia coli, Pseudomonas aeruginosa, Staphylococcus aureus, and Streptococcus pneumoniae

Biochemical characterization of beta-lactamases Bla1 and Bla2 from Bacillus anthracis

CAU-1, a subclass B3 metallo-beta-lactamase of low substrate affinity encoded by an ortholog present in the Caulobacter crescentus chromosome.

Carbapenem-resistant strain of Klebsiella oxytoca harboring carbapenem-hydrolyzing beta-lactamase KPC-2.

Cathelicidin Antimicrobial Peptides with Reduced Activation of Toll-Like Receptor Signaling Have Potent Bactericidal Activity against Colistin-Resistant Bacteria

Characterisation of Staphylococcus aureus and Enterococcus faecalis mutants with reduced susceptibility to the investigational oxazolidinone RWJ-416457 ⬇️

Characterization and dynamics of middle ear fluid and nasopharyngeal isolates of Streptococcus pneumoniae from 12 children treated with levofloxacin

Comment on: Redefining extended-spectrum -lactamases: balancing science and clinical need

Comment on: Resistance gene naming and numbering: is it a new gene or not?

Critical analysis of antibacterial agents in clinical development

Cross-resistance, relatedness and allele analysis of fluoroquinolone-resistant US clinical isolates of Streptococcus pneumoniae (1998-2000).

Detection systems for carbapenemase gene identification should include the SME serine carbapenemase

Differential selection of single-step AmpC or efflux mutants of Pseudomonas aeruginosa by using cefepime, ceftazidime, or ceftobiprole

Effect of MexXY overexpression on ceftobiprole susceptibility in Pseudomonas aeruginosa

Effects of ceftobiprole and oxacillin on mecA expression in methicillin-resistant Staphylococcus aureus clinical isolates

Effects of inoculum and beta-lactamase activity in AmpC- and extended-spectrum beta-lactamase (ESBL)-producing Escherichia coli and Klebsiella pneumoniae clinical isolates tested by using NCCLS ESBL methodology ⬇️

Effects of the 7-valent pneumococcal conjugate vaccine on U.S. levofloxacin-resistant Streptococcus pneumoniae

Epidemiology and risk factors for isolation of Escherichia coli producing CTX-M-type extended-spectrum β-lactamase in a large U.S. Medical Center.

Epidemiology of β-Lactamase-Producing Pathogens

Forgotten antibiotics: an inventory in Europe, the United States, Canada, and Australia

Game Changers: New β-Lactamase Inhibitor Combinations Targeting Antibiotic Resistance in Gram-Negative Bacteria

Hydrolysis and inhibition profiles of beta-lactamases from molecular classes A to D with doripenem, imipenem, and meropenem

Identification of a dithiazoline inhibitor of Escherichia coli L,D-carboxypeptidase A

In memoriam: John P. Quinn, MD.

In vitro activities of novel 2-fluoro-naphthyridine-containing ketolides

In vitro activity of ceftolozane-tazobactam as determined by broth dilution and agar diffusion assays against recent U.S. Escherichia coli isolates from 2010 to 2011 carrying CTX-M-type extended-spectrum β-lactamases

In vitro activity of plazomicin against β-lactamase-producing carbapenem-resistant Enterobacteriaceae (CRE).

In vitro antibacterial activities of JNJ-Q2, a new broad-spectrum fluoroquinolone

In vitro antibacterial activity of the pyrrolopyrazolyl-substituted oxazolidinone RWJ-416457.

In vitro susceptibility of characterized β-lactamase-producing strains tested with avibactam combinations.

In vitro susceptibility of β-lactamase-producing carbapenem-resistant Enterobacteriaceae (CRE) to eravacycline.

In vivo activity of ceftobiprole in murine skin infections due to Staphylococcus aureus and Pseudomonas aeruginosa

In vivo activity of the pyrrolopyrazolyl-substituted oxazolidinone RWJ-416457.

Infrequent occurrence of single mutations in topoisomerase IV and DNA gyrase genes among US levofloxacin-susceptible clinical isolates of Streptococcus pneumoniae from nine institutions (1999-2003).

Interactions of ceftobiprole with beta-lactamases from molecular classes A to D.

Interplay between β-lactamases and new β-lactamase inhibitors

Investigational antimicrobial agents of 2013.

Is it necessary to change the classification of {beta}-lactamases?

Molecular Correlation for the Treatment Outcomes in Bloodstream Infections Caused byEscherichia coliandKlebsiella pneumoniaewith Reduced Susceptibility to Ceftazidime ⬇️

MurF inhibitors with antibacterial activity: effect on muropeptide levels

Novel Carbapenem-Hydrolyzing β-Lactamase, KPC-1, from a Carbapenem-Resistant Strain of Klebsiella pneumoniae.

Novel antibacterial agents for the treatment of serious Gram-positive infections

Novel piperidinyloxy oxazolidinone antibacterial agents. Diversification of the N-Substituent

Past and Present Perspectives on β-Lactamases

Predominance of 23S rRNA mutants among non-erm, non-mef macrolide-resistant clinical isolates of Streptococcus pneumoniae collected in the United States in 1999-2000.

Preparation of erythromycin analogs having functional groups at C-15.

Prevalence of Single Mutations in Topoisomerase Type II Genes among Levofloxacin-Susceptible Clinical Strains of Streptococcus pneumoniae Isolated in the United States in 1992 to 1996 and 1999 to 2000 ⬇️

Publisher Correction: Interplay between β-lactamases and new β-lactamase inhibitors

Reply to Furlan et al., "Importance of Sequencing To Determine Functional blaTEM Variants".

SME-3, a novel member of the Serratia marcescens SME family of carbapenem-hydrolyzing beta-lactamases

Selection of hyperproduction of AmpC and SME-1 in a carbapenem-resistant Serratia marcescens isolate during antibiotic therapy

Synthesis and antibacterial activity of 3-O-acyl-6-O-carbamoyl erythromycin A derivatives

Synthesis and antibacterial activity of 3-keto-6-O-carbamoyl-11,12-cyclic thiocarbamate erythromycin A derivatives

Synthesis and antibacterial activity of 6-O-heteroarylcarbamoyl-11,12-lactoketolides

Synthesis and antibacterial activity of 7-(1,2,3,4-tetrahydropyrrolo[1,2-a]pyrazin-7-yl) quinolones.

Synthesis and antibacterial activity of C-6 carbamate ketolides, a novel series of orally active ketolide antibiotics

Synthesis and antibacterial activity of C2-fluoro, C6-carbamate ketolides, and their C9-oximes

Synthesis and antibacterial activity of C6-carbazate ketolides

Synthesis and antibacterial activity of pyrroloaryl-substituted oxazolidinones

TEM-71, a novel plasmid-encoded, extended-spectrum beta-lactamase produced by a clinical isolate of Klebsiella pneumoniae

Tackling antibiotic resistance

The Curious Case of TEM-116.

The synthesis and antimicrobial evaluation of a new series of isoxazolinyl oxazolidinones

Unusual Escherichia coli PBP 3 Insertion Sequence Identified from a Collection of Carbapenem-Resistant Enterobacteriaceae Tested In Vitro with a Combination of Ceftazidime-, Ceftaroline-, or Aztreonam-Avibactam