Lista de obras - Mirko Buchholz - Dominio Público Uruguay

3-Hydroxy-N'-arylidenepropanehydrazonamides with Halo-Substituted Phenanthrene Scaffolds Cure P. berghei Infected Mice When Administered Perorally

artículo científico publicado en 2017

A Primary Evaluation of Potential Small-Molecule Inhibitors of the Astacin Metalloproteinase Ovastacin, a Novel Drug Target in Female Infertility Treatment

scientific article published on 02 July 2020

Dipeptidyl-Peptidase Activity of Meprin β Links N-truncation of Aβ with Glutaminyl Cyclase-Catalyzed pGlu-Aβ Formation

artículo científico publicado en 2018

Expression of human and Porphyromonas gingivalis glutaminyl cyclases in periodontitis and rheumatoid arthritis-A pilot study

artículo científico publicado en 2018

First insight into structure-activity relationships of selective meprin β inhibitors.

artículo científico publicado en 2017

Heteroaromatic Inhibitors of the Astacin Proteinases Meprin α, Meprin β and Ovastacin Discovered by a Scaffold-Hopping Approach

artículo científico publicado en 2020

Hydrazides are potent transition-state analogs for glutaminyl cyclase implicated in the pathogenesis of Alzheimer's Disease

artículo científico publicado en 2020

Inhibition of glutaminyl cyclase prevents pGlu-Abeta formation after intracortical/hippocampal microinjection in vivo/in situ.

artículo científico publicado en 2008

Inhibitors for human glutaminyl cyclase by structure based design and bioisosteric replacement.

artículo científico publicado en 2009

Isolation, catalytic properties, and competitive inhibitors of the zinc-dependent murine glutaminyl cyclase.

artículo científico publicado en 2005

Natural Products from Microalgae with Potential against Alzheimer's Disease: Sulfolipids Are Potent Glutaminyl Cyclase Inhibitors

artículo científico publicado en 2016

Probing Secondary Glutaminyl Cyclase (QC) Inhibitor Interactions Applying an in silico‐Modeling/Site‐Directed Mutagenesis Approach: Implications for Drug Development ⬇️

artículo científico publicado el 11 de octubre de 2012

Semi-empirical derived descriptors for the modelling of properties of N-containing heterocycles.

artículo científico publicado en 2010

Structure-activity relationships of benzimidazole-based glutaminyl cyclase inhibitors featuring a heteroaryl scaffold.

artículo científico publicado en 2013

Structure-guided design, synthesis and characterization of next-generation meprin β inhibitors.

artículo científico publicado en 2018

Structures of Glycosylated Mammalian Glutaminyl Cyclases Reveal Conformational Variability near the Active Center ⬇️

artículo científico publicado el 27 de junio de 2011

Tertiary-Amine-Based Inhibitors of the Astacin Protease Meprin α

scholarly article by Kathrin Tan et al published 16 July 2018 in ChemMedChem

The first potent inhibitors for human glutaminyl cyclase: synthesis and structure-activity relationship.

artículo científico publicado en 2006

Lista de obras de Mirko Buchholz

3-Hydroxy-N'-arylidenepropanehydrazonamides with Halo-Substituted Phenanthrene Scaffolds Cure P. berghei Infected Mice When Administered Perorally

A Primary Evaluation of Potential Small-Molecule Inhibitors of the Astacin Metalloproteinase Ovastacin, a Novel Drug Target in Female Infertility Treatment

Dipeptidyl-Peptidase Activity of Meprin β Links N-truncation of Aβ with Glutaminyl Cyclase-Catalyzed pGlu-Aβ Formation

Expression of human and Porphyromonas gingivalis glutaminyl cyclases in periodontitis and rheumatoid arthritis-A pilot study

First insight into structure-activity relationships of selective meprin β inhibitors.

Heteroaromatic Inhibitors of the Astacin Proteinases Meprin α, Meprin β and Ovastacin Discovered by a Scaffold-Hopping Approach

Hydrazides are potent transition-state analogs for glutaminyl cyclase implicated in the pathogenesis of Alzheimer's Disease

Inhibition of glutaminyl cyclase prevents pGlu-Abeta formation after intracortical/hippocampal microinjection in vivo/in situ.

Inhibitors for human glutaminyl cyclase by structure based design and bioisosteric replacement.

Isolation, catalytic properties, and competitive inhibitors of the zinc-dependent murine glutaminyl cyclase.

Natural Products from Microalgae with Potential against Alzheimer's Disease: Sulfolipids Are Potent Glutaminyl Cyclase Inhibitors

Probing Secondary Glutaminyl Cyclase (QC) Inhibitor Interactions Applying an in silico‐Modeling/Site‐Directed Mutagenesis Approach: Implications for Drug Development ⬇️

Semi-empirical derived descriptors for the modelling of properties of N-containing heterocycles.

Structure-activity relationships of benzimidazole-based glutaminyl cyclase inhibitors featuring a heteroaryl scaffold.

Structure-guided design, synthesis and characterization of next-generation meprin β inhibitors.

Structures of Glycosylated Mammalian Glutaminyl Cyclases Reveal Conformational Variability near the Active Center ⬇️

Tertiary-Amine-Based Inhibitors of the Astacin Protease Meprin α

The first potent inhibitors for human glutaminyl cyclase: synthesis and structure-activity relationship.