Lista de obras - Paolo Cappella - Dominio Público Uruguay

1,4,5,6-tetrahydropyrrolo[3,4-c]pyrazoles: identification of a potent Aurora kinase inhibitor with a favorable antitumor kinase inhibition profile.

artículo científico publicado en 2006

5-(2-Amino-pyrimidin-4-yl)-1H-pyrrole and 2-(2-amino-pyrimidin-4-yl)-1,5,6,7-tetrahydro-pyrrolo[3,2-c]pyridin-4-one derivatives as new classes of selective and orally available Polo-like kinase 1 inhibitors ⬇️

artículo científico publicado el 23 de noviembre de 2011

A Novel High-Content Immunofluorescence Assay as a Tool to Identify at the Single Cell Level γ-Globin Inducing Compounds

artículo científico publicado en 2015

Application of click chemistry conditions for 5-bromo-2'-deoxyuridine determination through Fenton and related reactions.

artículo científico publicado en 2015

Cell Proliferation Method: Click Chemistry Based on BrdU Coupling for Multiplex Antibody Staining.

artículo científico publicado en 2015

Cell proliferation method: click chemistry based on BrdU coupling for multiplex antibody staining.

artículo científico publicado en 2008

Characterization of cyclin B1 expression in human cancer cell lines by a new three-parameter BrdUrd/cyclin B1/DNA analysis

scientific article published on 01 January 1998

CyTOF Mass Cytometry for Click Proliferation Assays.

artículo científico publicado en 2017

FOXM1 expression is significantly associated with chemotherapy resistance and adverse prognosis in non-serous epithelial ovarian cancer patients

artículo científico publicado en 2017

From “Click” to “Fenton” chemistry for 5‐bromo‐2′‐deoxyuridine determination ⬇️

artículo científico publicado el 13 de agosto de 2013

Highly Multiplexed Phenotypic Imaging for Cell Proliferation Studies ⬇️

artículo científico publicado el 29 de julio de 2013

Identification of 4,5-dihydro-1H-pyrazolo[4,3-h]quinazoline derivatives as a new class of orally and selective Polo-like kinase 1 inhibitors

artículo científico publicado en 2010

In vivo imaging of early stage apoptosis by measuring real-time caspase-3/7 activation.

artículo científico publicado en 2011

Interpreting cell cycle effects of drugs: the case of melphalan.

artículo científico publicado en 2005

Measuring the complexity of cell cycle arrest and killing of drugs: kinetics of phase-specific effects induced by taxol

scientific article published on 01 October 1999

Miniaturizing bromodeoxyuridine incorporation enables the usage of flow cytometry for cell cycle analysis of adherent tissue culture cells for high throughput screening.

artículo científico publicado en 2010

Multiparametric cell cycle analysis by automated microscopy

scientific article published on 14 July 2006

NMS-P937, an orally available, specific small-molecule polo-like kinase 1 inhibitor with antitumor activity in solid and hematologic malignancies.

artículo científico publicado en 2012

PHA-680632, a novel Aurora kinase inhibitor with potent antitumoral activity.

artículo científico publicado en 2006

PHA-739358, a potent inhibitor of Aurora kinases with a selective target inhibition profile relevant to cancer.

artículo científico publicado en 2007

Targeting the mitotic checkpoint for cancer therapy with NMS-P715, an inhibitor of MPS1 kinase

artículo científico publicado en 2010

Thieno[3,2-c]pyrazoles: a novel class of Aurora inhibitors with favorable antitumor activity

artículo científico publicado en 2010

Transcriptional analysis of the Aurora inhibitor Danusertib leading to biomarker identification in TP53 wild type cells

artículo científico publicado en 2011

Lista de obras de Paolo Cappella

1,4,5,6-tetrahydropyrrolo[3,4-c]pyrazoles: identification of a potent Aurora kinase inhibitor with a favorable antitumor kinase inhibition profile.

5-(2-Amino-pyrimidin-4-yl)-1H-pyrrole and 2-(2-amino-pyrimidin-4-yl)-1,5,6,7-tetrahydro-pyrrolo[3,2-c]pyridin-4-one derivatives as new classes of selective and orally available Polo-like kinase 1 inhibitors ⬇️

A Novel High-Content Immunofluorescence Assay as a Tool to Identify at the Single Cell Level γ-Globin Inducing Compounds

Application of click chemistry conditions for 5-bromo-2'-deoxyuridine determination through Fenton and related reactions.

Cell Proliferation Method: Click Chemistry Based on BrdU Coupling for Multiplex Antibody Staining.

Cell proliferation method: click chemistry based on BrdU coupling for multiplex antibody staining.

Characterization of cyclin B1 expression in human cancer cell lines by a new three-parameter BrdUrd/cyclin B1/DNA analysis

CyTOF Mass Cytometry for Click Proliferation Assays.

FOXM1 expression is significantly associated with chemotherapy resistance and adverse prognosis in non-serous epithelial ovarian cancer patients

From “Click” to “Fenton” chemistry for 5‐bromo‐2′‐deoxyuridine determination ⬇️

Highly Multiplexed Phenotypic Imaging for Cell Proliferation Studies ⬇️

Identification of 4,5-dihydro-1H-pyrazolo[4,3-h]quinazoline derivatives as a new class of orally and selective Polo-like kinase 1 inhibitors

In vivo imaging of early stage apoptosis by measuring real-time caspase-3/7 activation.

Interpreting cell cycle effects of drugs: the case of melphalan.

Measuring the complexity of cell cycle arrest and killing of drugs: kinetics of phase-specific effects induced by taxol

Miniaturizing bromodeoxyuridine incorporation enables the usage of flow cytometry for cell cycle analysis of adherent tissue culture cells for high throughput screening.

Multiparametric cell cycle analysis by automated microscopy

NMS-P937, an orally available, specific small-molecule polo-like kinase 1 inhibitor with antitumor activity in solid and hematologic malignancies.

PHA-680632, a novel Aurora kinase inhibitor with potent antitumoral activity.

PHA-739358, a potent inhibitor of Aurora kinases with a selective target inhibition profile relevant to cancer.

Targeting the mitotic checkpoint for cancer therapy with NMS-P715, an inhibitor of MPS1 kinase

Thieno[3,2-c]pyrazoles: a novel class of Aurora inhibitors with favorable antitumor activity

Transcriptional analysis of the Aurora inhibitor Danusertib leading to biomarker identification in TP53 wild type cells