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2,7-Bis-(4-amidinobenzylidene)-cycloheptan-1-one dihydrochloride, tPA stop, prevents tPA-enhanced excitotoxicity both in vitro and in vivo

artículo científico publicado en 2004

A Zic2-regulated switch in a noncanonical Wnt/βcatenin pathway is essential for the formation of bilateral circuits

artículo científico publicado en 2020

A protocol to extract cell-type-specific signatures from differentially expressed genes in bulk-tissue RNA-seq

artículo científico publicado en 2022

Anti-NR1 N-terminal-domain vaccination unmasks the crucial action of tPA on NMDA-receptor-mediated toxicity and spatial memory.

artículo científico publicado en 2007

Arginine 260 of the amino-terminal domain of NR1 subunit is critical for tissue-type plasminogen activator-mediated enhancement of N-methyl-D-aspartate receptor signaling

artículo científico publicado en 2004

Blocking miRNA Biogenesis in Adult Forebrain Neurons Enhances Seizure Susceptibility, Fear Memory, and Food Intake by Increasing Neuronal Responsiveness.

artículo científico publicado en 2015

Brain size regulations by cbp haploinsufficiency evaluated by in-vivo MRI based volumetry

artículo científico publicado en 2015

Can changes in histone acetylation contribute to memory formation?

artículo científico publicado en 2014

Cbp-dependent histone acetylation mediates axon regeneration induced by environmental enrichment in rodent spinal cord injury models

artículo científico publicado en 2019

Development and maintenance of the brain's immune toolkit: Microglia and non-parenchymal brain macrophages

artículo científico publicado en 2017

Ecdysone-Induced 3D Chromatin Reorganization Involves Active Enhancers Bound by Pipsqueak and Polycomb

scientific article published on 01 September 2019

Equivocal roles of tissue-type plasminogen activator in stroke-induced injury

artículo científico publicado en 2004

Genomic targets, and histone acetylation and gene expression profiling of neural HDAC inhibition

artículo científico publicado el 1 de julio de 2013

Histone H3 lysine methylation in cognition and intellectual disability disorders.

artículo científico publicado en 2013

Histone acetylation deficits in lymphoblastoid cell lines from patients with Rubinstein-Taybi syndrome.

artículo científico publicado en 2011

Is tissue-type plasminogen activator a neuromodulator?

artículo científico publicado en 2004

Lack of IL-1R8 in neurons causes hyperactivation of IL-1 receptor pathway and induces MECP2-dependent synaptic defects

artículo científico publicado en 2017

Loss of Kdm5c Causes Spurious Transcription and Prevents the Fine-Tuning of Activity-Regulated Enhancers in Neurons.

artículo científico publicado en 2017

Loss of neuronal 3D chromatin organization causes transcriptional and behavioural deficits related to serotonergic dysfunction

artículo científico publicado en 2014

Lysine acetyltransferases CBP and p300 as therapeutic targets in cognitive and neurodegenerative disorders.

artículo científico

Recombinant Desmodus rotundus salivary plasminogen activator crosses the blood-brain barrier through a low-density lipoprotein receptor-related protein-dependent mechanism without exerting neurotoxic effects

artículo científico publicado en 2007

SFRP1 modulates astrocyte-to-microglia crosstalk in acute and chronic neuroinflammation

artículo científico publicado en 2021

Secondary loss of <i>miR-3607</i> reduced cortical progenitor amplification during rodent evolution

artículo científico publicado en 2022

Selective boosting of transcriptional and behavioral responses to drugs of abuse by histone deacetylase inhibition.

artículo científico publicado en 2009

Specific promoter deacetylation of histone H3 is conserved across mouse models of Huntington's disease in the absence of bulk changes.

artículo científico publicado en 2016

The brain-specific tissue-type plasminogen activator inhibitor, neuroserpin, protects neurons against excitotoxicity both in vitro and in vivo

artículo científico publicado en 2005

Tissue-type plasminogen activator crosses the intact blood-brain barrier by low-density lipoprotein receptor-related protein-mediated transcytosis

artículo científico publicado en 2005

Tissue-type plasminogen activator rescues neurones from serum deprivation-induced apoptosis through a mechanism independent of its proteolytic activity

artículo científico publicado en 2006

Toward safer thrombolytic agents in stroke: molecular requirements for NMDA receptor-mediated neurotoxicity.

artículo científico publicado en 2008