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Lista de obras de Philippe Valet

A biomimetic hydrogel functionalized with adipose ECM components as a microenvironment for the 3D culture of human and murine adipocytes.

artículo científico publicado en 2017

A simple and highly sensitive radioenzymatic assay for lysophosphatidic acid quantification.

artículo científico publicado en 2000

Absence of arterial hypertension despite chronic plasma noradrenaline elevation: evidence for down-regulation of alpha-adrenoceptors. A case report

scientific article published on 01 January 1991

Acute release of catecholamines on circulating blood cell adrenoceptors and metabolic indices in dog

artículo científico publicado en 1988

Adipocyte Exosomes Promote Melanoma Aggressiveness through Fatty Acid Oxidation: A Novel Mechanism Linking Obesity and Cancer.

artículo científico publicado en 2016

Adipocytes promote breast cancer resistance to chemotherapy, a process amplified by obesity: role of the major vault protein (MVP)

artículo científico publicado en 2019

Adipokine expression profile in adipocytes of different mouse models of obesity.

artículo científico publicado en 2005

Adipose tissue and breast epithelial cells: a dangerous dynamic duo in breast cancer.

artículo científico

Adipose-specific disruption of autotaxin enhances nutritional fattening and reduces plasma lysophosphatidic acid ⬇️

artículo científico publicado el 18 de marzo de 2011

Adrenergic supersensitivity in parkinsonians with orthostatic hypotension

artículo científico publicado en 1990

Adrenoceptors in the diagnosis of phaeochromocytoma

scientific article published on 01 August 1987

Alpha 2-adrenergic stimulation promotes preadipocyte proliferation. Involvement of mitogen-activated protein kinases.

artículo científico publicado en 1994

Alpha2-adrenergic receptor-mediated release of lysophosphatidic acid by adipocytes. A paracrine signal for preadipocyte growth ⬇️

artículo científico publicado el 1 de abril de 1998

Alterations of lipid metabolism and gene expression in rat adipocytes during chronic olanzapine treatment

scientific article published on 09 January 2007

Altered food consumption in mice lacking lysophosphatidic acid receptor-1.

artículo científico publicado en 2009

Altered gut microbiota and endocannabinoid system tone in obese and diabetic leptin-resistant mice: impact on apelin regulation in adipose tissue.

artículo científico publicado en 2011

Amine oxidase substrates for impaired glucose tolerance correction.

artículo científico publicado en 2005

Androgenic regulation of adipocyte alpha 2-adrenoceptor expression in male and female Syrian hamsters: proposed transcriptional mechanism ⬇️

artículo científico publicado el 1 de enero de 1992

Antilipolytic effects of alpha 2-adrenergic agonists, neuropeptide Y, adenosine, and PGE1 in mammal adipocytes.

artículo científico publicado en 1994

Apelin administration improves insulin sensitivity in overweight men during hyperinsulinaemic-euglycaemic clamp.

artículo científico publicado en 2017

Apelin affects the mouse aging urinary peptidome with minimal effects on kidney

scientific article published on 23 July 2019

Apelin and energy metabolism.

artículo científico publicado en 2015

Apelin is a novel islet peptide.

artículo científico publicado en 2010

Apelin modulates pathological remodeling of lymphatic endothelium after myocardial infarction

artículo científico publicado en 2017

Apelin prevents cardiac fibroblast activation and collagen production through inhibition of sphingosine kinase 1.

artículo científico publicado en 2011

Apelin receptors: From signaling to antidiabetic strategy.

artículo científico

Apelin regulates FoxO3 translocation to mediate cardioprotective responses to myocardial injury and obesity.

artículo científico publicado en 2015

Apelin stimulates both cholecystokinin and glucagon-like peptide 1 secretions in vitro and in vivo in rodents.

artículo científico publicado en 2013

Apelin stimulates glucose uptake but not lipolysis in human adipose tissue ex vivo ⬇️

artículo científico publicado el 19 de enero de 2011

Apelin stimulates glucose utilization in normal and obese insulin-resistant mice

artículo científico publicado en 2008

Apelin targets gut contraction to control glucose metabolism via the brain

artículo científico publicado en 2015

Apelin treatment increases complete Fatty Acid oxidation, mitochondrial oxidative capacity, and biogenesis in muscle of insulin-resistant mice.

artículo científico publicado en 2011

Apelin, a promising target for type 2 diabetes treatment?

artículo científico

Apelin, diabetes, and obesity.

scientific article published on August 2011

Apelin-13 administration protects against ischaemia/reperfusion-mediated apoptosis through the FoxO1 pathway in high-fat diet-induced obesity.

artículo científico publicado en 2016

Apelin: an antithrombotic factor that inhibits platelet function.

artículo científico publicado en 2015

Benzylamine antihyperglycemic effect is abolished by AOC3 gene invalidation in mice but not rescued by semicarbazide-sensitive amine oxidase expression under the control of aP2 promoter

artículo científico publicado en 2012

Benzylamine exhibits insulin-like effects on glucose disposal, glucose transport, and fat cell lipolysis in rabbits and diabetic mice.

artículo científico publicado en 2004

Beta-1 adrenergic inhibition of kallikrein release from rat kidney cortical slices

scientific article published on 01 May 1990

Brain glucagon-like peptide 1 signaling controls the onset of high-fat diet-induced insulin resistance and reduces energy expenditure.

artículo científico publicado en 2008

Ca(2+)-independent phospholipase A2 is required for alpha2-adrenergic-induced preadipocyte spreading.

artículo científico publicado en 1999

Cancer-associated adipose tissue promotes breast cancer progression by paracrine oncostatin M and Jak/STAT3 signaling.

artículo científico publicado en 2014

Cardiac beta-adrenoceptors and adenylyl cyclase activity in human left ventricular hypertrophy due to pressure overload

artículo científico publicado en 1994

Catalytic dysregulation of SHP2 leading to Noonan syndromes affects platelet signaling and functions

artículo científico publicado en 2019

Cathepsin-D, a key protease in breast cancer, is up-regulated in obese mouse and human adipose tissue, and controls adipogenesis

artículo científico publicado en 2011

Central Apelin Controls Glucose Homeostasis via a Nitric Oxide-Dependent Pathway in Mice

artículo científico publicado en 2011

Central chronic apelin infusion decreases energy expenditure and thermogenesis in mice.

artículo científico publicado en 2016

Changes in beta-adrenergic receptivity during human left ventricular hypertrophy due to pressure overload

artículo científico publicado en 1993

Characterization and distribution of alpha 2-adrenergic receptors in the human intestinal mucosa

artículo científico publicado en 1993

Chronic apelin treatment improves hepatic lipid metabolism in obese and insulin-resistant mice by an indirect mechanism.

artículo científico publicado en 2018

Circadian Feeding Drive of Metabolic Activity in Adipose Tissue and not Hyperphagia Triggers Overweight in Mice: Is There a Role of the Pentose-Phosphate Pathway?

artículo científico publicado en 2011

Cognitive deficit in hippocampal-dependent tasks in Werner syndrome mouse model.

artículo científico publicado en 2017

Corrigendum: Matrix metalloproteinase 11 protects from diabesity and promotes metabolic switch

artículo científico publicado en 2016

Culture of human adipose tissue explants leads to profound alteration of adipocyte gene expression.

artículo científico publicado en 2003

Decreased Resistin Expression in Mice with Different Sensitivities to a High-Fat Diet

artículo científico publicado en 2001

Depot-specific regulation of autotaxin with obesity in human adipose tissue

artículo científico publicado en 2012

Diet-induced obesity and associated disorders are prevented by natural bioactive type 1 fish collagen peptides (Naticol®) treatment

scientific article published on 19 September 2018

Differential regulation of fat cell beta-2 and beta-1 adrenoceptors by endogenous catecholamines in dog

artículo científico publicado en 1989

Dissemination of prostate cancer: a way paved of fat

artículo científico publicado en 2016

Distribution of PYY receptors in human fat cells: an antilipolytic system alongside the alpha 2-adrenergic system

artículo científico publicado en 1993

Effect of hypocaloric diet-induced weight loss in obese women on plasma apelin and adipose tissue expression of apelin and APJ.

scientific article published on 07 April 2008

Effect of non-digestible gluco-oligosaccharides on glucose sensitivity in high fat diet fed mice.

artículo científico publicado en 2003

Effects of dietary eicosapentaenoic acid (EPA) supplementation in high-fat fed mice on lipid metabolism and apelin/APJ system in skeletal muscle.

artículo científico publicado en 2013

Effects of histamine on triglyceride breakdown in mouse adipocytes

artículo científico publicado en 2007

Effects of oral administration of benzylamine on glucose tolerance and lipid metabolism in rats.

artículo científico publicado en 2005

Esophageal cancer cells resistant to T-DM1 display alterations in cell adhesion and the prostaglandin pathway.

artículo científico publicado en 2018

Expanding role for the apelin/APJ system in physiopathology.

artículo científico publicado en 2007

Experimental and clinical approaches to treatment of hypertension by dopamine receptor agonists.

artículo científico publicado en 1987

Food intake adaptation to dietary fat involves PSA-dependent rewiring of the arcuate melanocortin system in mice.

artículo científico publicado en 2012

Functional consequences of constitutively active alpha2A-adrenergic receptor expression in 3T3F442A preadipocytes and adipocytes.

artículo científico publicado en 1997

Galanin enhances systemic glucose metabolism through enteric Nitric Oxide Synthase-expressed neurons

artículo científico publicado en 2018

Glucose handling in streptozotocin-induced diabetic rats is improved by tyramine but not by the amine oxidase inhibitor semicarbazide.

artículo científico publicado en 2005

Human adipocytes express alpha 2-adrenergic receptor of the alpha 2A-subtype only: pharmacological and genetic evidence.

artículo científico publicado en 1995

Human alpha 2A-adrenergic receptor gene expressed in transgenic mouse adipose tissue under the control of its regulatory elements.

artículo científico publicado en 2002

Hypothalamic apelin/reactive oxygen species signaling controls hepatic glucose metabolism in the onset of diabetes.

artículo científico publicado en 2013

Hypoxia inhibits Cavin-1 and Cavin-2 expression and down-regulates caveolae in adipocytes.

artículo científico publicado en 2014

Identification and functional studies of a specific peptide YY-preferring receptor in dog adipocytes

artículo científico publicado en 1992

Impact of hypothalamic reactive oxygen species in the regulation of energy metabolism and food intake

artículo científico publicado en 2015

Impairment of adipose tissue in Prader-Willi syndrome rescued by growth hormone treatment

artículo científico publicado en 2014

Improvement of cardiometabolic markers after fish oil intervention in young Mexican adults and the role of PPARα L162V and PPARγ2 P12A.

artículo científico publicado en 2017

In vitro and in vivo impairment of alpha2-adrenergic receptor-dependent antilipolysis by fatty acids in human adipose tissue.

artículo científico publicado en 2001

In vivo upregulation of adipocyte alpha 2-adrenoceptors by androgens is consequence of direct action on fat cells

scientific article published on 01 October 1994

Increased monoamine oxidase and semicarbazide-sensitive amine oxidase activities in white adipose tissue of obese dogs fed a high-fat diet

artículo científico publicado en 2006

Influence of high-fat diet on amine oxidase activity in white adipose tissue of mice prone or resistant to diet-induced obesity.

artículo científico publicado en 2005

Influence of secreted factors from human adipose tissue on glucose utilization and proinflammatory reaction ⬇️

artículo científico publicado el 27 de enero de 2013

Inhibition of PIKfyve prevents myocardial apoptosis and hypertrophy through activation of SIRT3 in obese mice.

artículo científico publicado en 2017

Involvement of cholecystokinin 2 receptor in food intake regulation: hyperphagia and increased fat deposition in cholecystokinin 2 receptor-deficient mice.

artículo científico publicado en 2006

Is Crohn's creeping fat an adipose tissue?

artículo científico publicado en 2011

Is adrenal medulla involved in the antihypertensive effect of nicardipine?

artículo científico publicado en 1988

Isoprostanes as markers for muscle aging in older athletes.

artículo científico publicado en 2017

Jejunum Inflammation in Obese and Diabetic Mice Impairs Enteric Glucose Detection and Modifies Nitric Oxide Release in the Hypothalamus

scientific article published on 29 September 2010

LEOPARD syndrome-associated SHP2 mutation confers leanness and protection from diet-induced obesity

artículo científico publicado en 2014

LPA as a paracrine mediator of adipocyte growth and function.

artículo científico publicado en 2000

LRP1 receptor controls adipogenesis and is up-regulated in human and mouse obese adipose tissue.

artículo científico publicado en 2009

Levodopa up-regulates platelet alpha 2-adrenoceptors

artículo científico publicado en 1990

Lipolysis is altered in MHC class I zinc-alpha(2)-glycoprotein deficient mice.

artículo científico publicado en 2007

Lipomobilizing effects of procaterol and yohimbine in the conscious dog: comparison of endocrinological, metabolic and cardiovascular effects

artículo científico publicado en 1989

Lipopolysaccharides-mediated increase in glucose-stimulated insulin secretion: involvement of the GLP-1 pathway.

artículo científico publicado en 2013

Lysophosphatidic acid and renal fibrosis.

artículo científico publicado en 2008

Lysophosphatidic acid impairs glucose homeostasis and inhibits insulin secretion in high-fat diet obese mice.

artículo científico publicado en 2013

Lysophosphatidic acid synthesis and release

scientific journal article

Lysophosphatidic acid-1-receptor targeting agents for fibrosis.

artículo científico publicado en 2011

Mammary adipocytes stimulate breast cancer invasion through metabolic remodeling of tumor cells.

artículo científico publicado en 2017

Maternal hypertension induces tissue-specific modulations of the apelinergic system in the fetoplacental unit in rat

artículo científico publicado en 2012

Matrix metalloproteinase 11 protects from diabesity and promotes metabolic switch

artículo científico publicado en 2016

Metabolic endotoxemia directly increases the proliferation of adipocyte precursors at the onset of metabolic diseases through a CD14-dependent mechanism

artículo científico publicado en 2013

Methylamine but not mafenide mimics insulin-like activity of the semicarbazide-sensitive amine oxidase-substrate benzylamine on glucose tolerance and on human adipocyte metabolism.

artículo científico publicado en 2005

Mildly oxidized LDL evokes a sustained Ca(2+)-dependent retraction of vascular smooth muscle cells

artículo científico publicado en 1996

Modifications of mesenteric adipose tissue during moderate experimental colitis in mice.

artículo científico publicado en 2013

Molecular mechanisms underlying regional variations of catecholamine-induced lipolysis in rat adipocytes

artículo científico publicado en 1995

Myocardial hypertrophy, cardiac beta-adrenoceptors and adenylate cyclase activity during sinoaortic denervation in dogs.

artículo científico publicado en 1992

Native fructose extracted from apple improves glucose tolerance in mice.

artículo científico publicado en 2009

Neuromedin U is a gut peptide that alters oral glucose tolerance by delaying gastric emptying via direct contraction of the pylorus and vagal-dependent mechanisms

scientific article published on 12 February 2019

Noonan syndrome-causing SHP2 mutants impair ERK-dependent chondrocyte differentiation during endochondral bone growth

artículo científico publicado en 2018

Noonan syndrome-causing SHP2 mutants inhibit insulin-like growth factor 1 release via growth hormone-induced ERK hyperactivation, which contributes to short stature.

artículo científico publicado en 2012

Nuclear HMGB1 protects from nonalcoholic fatty liver disease through negative regulation of liver X receptor

artículo científico publicado en 2022

Obesity-induced lymphocyte hyperresponsiveness to chemokines: a new mechanism of Fatty liver inflammation in obese mice.

artículo científico publicado en 2008

Periprostatic Adipose Tissue Favors Prostate Cancer Cell Invasion in an Obesity-Dependent Manner: Role of Oxidative Stress

scientific article published on 03 January 2019

Periprostatic adipocytes act as a driving force for prostate cancer progression in obesity

artículo científico publicado en 2016

Pharmacological targeting of apelin impairs glioblastoma growth.

artículo científico publicado en 2017

Plasma catecholamines and adrenoceptors after chronic sinoaortic denervation in dogs

artículo científico publicado en 1989

Platelet alpha 2- and leucocyte beta 2-adrenoceptors in phaeochromocytoma: effect of tumour removal

artículo científico publicado en 1988

Positive regulation of DNA double strand break repair activity during differentiation of long life span cells: the example of adipogenesis

artículo científico publicado en 2008

Pro-fibrotic activity of lysophosphatidic acid in adipose tissue: in vivo and in vitro evidence.

artículo científico publicado en 2013

Prolonged treatment with aminoguanidine strongly inhibits adipocyte semicarbazide-sensitive amine oxidase and slightly reduces fat deposition in obese Zucker rats.

artículo científico publicado en 2007

Protamine is an antagonist of apelin receptor, and its activity is reversed by heparin.

artículo científico publicado en 2017

Recent advances in the pharmacology of rilmenidine.

artículo científico publicado en 1989

Regulation of SREBPs by Sphingomyelin in Adipocytes via a Caveolin and Ras-ERK-MAPK-CREB Signaling Pathway

artículo científico publicado en 2015

Regulation of fat-cell function by alpha 2-adrenergic receptors.

artículo científico publicado en 1998

Regulation of secreted protein acidic and rich in cysteine during adipose conversion and adipose tissue hyperplasia.

artículo científico publicado en 2006

Relationship between arterial blood pressure disturbances and alpha adrenoceptor density

scientific article published on 01 May 1994

Rilmenidine (S 3341) and the sympathoadrenal system: adrenoreceptors, plasma and adrenal catecholamines in dogs

artículo científico publicado en 1988

SHP2 sails from physiology to pathology.

artículo científico

SSAO Substrates Exhibiting Insulin-Like Effects in Adipocytes as a Promising Treatment Option for Metabolic Disorders ⬇️

artículo científico publicado el 1 de diciembre de 2010

Semicarbazide-sensitive amine oxidase substrates fail to induce insulin-like effects in fat cells from AOC3 knockout mice

artículo científico publicado en 2007

Semicarbazide-sensitive amine oxidase/vascular adhesion protein-1 deficiency reduces leukocyte infiltration into adipose tissue and favors fat deposition.

artículo científico publicado en 2009

Simultaneous quantitative profiling of 20 isoprostanoids from omega-3 and omega-6 polyunsaturated fatty acids by LC-MS/MS in various biological samples

artículo científico publicado en 2016

Structural apelin analogues: mitochondrial ROS inhibition and cardiometabolic protection in myocardial ischaemia reperfusion injury

artículo científico publicado en 2015

TNFalpha up-regulates apelin expression in human and mouse adipose tissue.

artículo científico publicado en 2006

The APJ receptor: a new therapeutic approach in diabetic treatment

artículo científico publicado en 2015

The Gut Microbiota Regulates Intestinal CD4 T Cells Expressing RORγt and Controls Metabolic Disease

artículo científico publicado en 2015

The apelin/APJ system as a therapeutic target in metabolic diseases

scientific article published on 10 January 2019

The exerkine apelin reverses age-associated sarcopenia

scientific article published on 30 July 2018

The imidazoline I2-site ligands BU 224 and 2-BFI inhibit MAO-A and MAO-B activities, hydrogen peroxide production, and lipolysis in rodent and human adipocytes.

artículo científico publicado en 2006

The intestinal glucose-apelin cycle controls carbohydrate absorption in mice

artículo científico publicado en 2013

The miR-379/miR-410 cluster at the imprinted Dlk1-Dio3 domain controls neonatal metabolic adaptation

artículo científico publicado en 2014

The use of urinary proteomics in the assessment of suitability of mouse models for ageing

artículo científico publicado en 2017

The uterine and vascular actions of estetrol delineate a distinctive profile of estrogen receptor α modulation, uncoupling nuclear and membrane activation

artículo científico publicado en 2014

Therapeutic Benefit and Gene Network Regulation by Combined Gene Transfer of Apelin, FGF2, and SERCA2a into Ischemic Heart.

artículo científico publicado en 2017

Transition from metabolic adaptation to maladaptation of the heart in obesity: role of apelin

artículo científico publicado en 2014

Triggering the adaptive immune system with commensal gut bacteria protects against insulin resistance and dysglycemia

artículo científico publicado en 2016

Urinary kallikrein excretion in neurogenic hypertension in the dogs: possible relationship between kallikrein excretion and catecholamines

scientific article published on 01 January 1989

Vasoactive intestinal peptide and forskolin regulate proliferation of the HT29 human colon adenocarcinoma cell line

artículo científico publicado el 1 de marzo de 1992

Verapamil interacts in vitro with alpha 2-adrenoceptors but does not modify alpha 2-receptivity in vivo

artículo científico publicado en 1989

[Adipose tissue and cancer: a high risk tandem]

artículo científico publicado en 2014

[Alpha 2-adrenergic receptors and arterial pressure]

artículo científico publicado en 1989

[Beta adrenergic receptors and experimental left ventricular hypertrophy]

artículo científico publicado en 1992

[Beta-adrenergic receptivity and left ventricular hypertrophy caused by pressure overload in man]

scientific article published on 01 August 1993

[Changes in myocardial beta adrenergic receptors in left ventricular hypertrophy caused by barometric and volumetric overloads]

artículo científico publicado en 1994

[Development of nutritional obesity in transgenic mice with an adrenergic receptivity in adipose tissue comparable with that of humans]

scientific article published on 01 February 2002

[Metabolic and trophic role of catecholamines in the development of white adipose tissue]

scientific article published on 01 September 1999

[Myocardial beta-adrenergic receptors and left ventricular hypertrophy induced by pressure overload in man]

artículo científico publicado en 1992

[Value of the study of circulating adrenergic receptors in the diagnosis and surveillance after surgery of pheochromocytoma]

artículo científico publicado en 1988

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