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Lista de obras de Eric Batchelor

A synthetic-natural hybrid oscillator in human cells

artículo científico publicado en 2010

Abstract 3116: Dysregulated cholesterol synthesis is a therapeutic vulnerability in glioblastoma

artículo científico publicado en 2017

Abstract B097: Dysregulated mevalonate and cholesterol synthesis is a therapeutic vulnerability in glioblastoma

artículo científico publicado en 2018

Basal dynamics of p53 reveal transcriptionally attenuated pulses in cycling cells.

artículo científico publicado en 2010

CRISPR/Cas9-mediated gene knockout is insensitive to target copy number but is dependent on guide RNA potency and Cas9/sgRNA threshold expression level.

artículo científico publicado en 2017

Continuous control in bacterial regulatory circuits

artículo científico publicado en 2004

Determining the Limitations and Benefits of Noise in Gene Regulation and Signal Transduction through Single Cell, Microscopy-Based Analysis

artículo científico publicado en 2017

Disabled cell density sensing leads to dysregulated cholesterol synthesis in glioblastoma.

artículo científico publicado en 2017

Dissecting transcriptional amplification by MYC

scientific article published on 27 July 2020

FUBP1 and FUBP2 enforce distinct epigenetic setpoints for MYC expression in primary single murine cells

scientific article published on 01 October 2020

Far Upstream Element Binding Protein Plays a Crucial Role in Embryonic Development, Hematopoiesis, and Stabilizing Myc Expression Levels.

artículo científico publicado en 2016

Flexible CRISPR library construction using parallel oligonucleotide retrieval.

artículo científico publicado en 2017

Fourier analysis and systems identification of the p53 feedback loop

artículo científico publicado en 2010

Global Inhibition with Specific Activation: How p53 and MYC Redistribute the Transcriptome in the DNA Double-Strand Break Response

artículo científico publicado en 2017

Imaging OmpR localization in Escherichia coli

artículo científico publicado en 2006

METB-03. DISABLED CELL DENSITY SENSING BY TUMOR SUPPRESSORS LEADS TO DYSREGULATED CHOLESTEROL SYNTHESIS IN GLIOBLASTOMA

artículo científico publicado en 2016

Modeling cell heterogeneity: from single-cell variations to mixed cells

artículo científico publicado en 2013

Myc Regulates Chromatin Decompaction and Nuclear Architecture during B Cell Activation

artículo científico publicado en 2017

NFκB Promotes Ovarian Tumorigenesis via Classical Pathways That Support Proliferative Cancer Cells and Alternative Pathways That Support ALDH+ Cancer Stem-like Cells.

artículo científico publicado en 2017

Promoter decoding of transcription factor dynamics.

artículo científico publicado en 2013

Protein stability of p53 targets determines their temporal expression dynamics in response to p53 pulsing

scientific article published on 11 February 2019

Recent progress and open challenges in modeling p53 dynamics in single cells

artículo científico publicado en 2017

Recurrent initiation: a mechanism for triggering p53 pulses in response to DNA damage.

artículo científico publicado en 2008

Robustness and the cycle of phosphorylation and dephosphorylation in a two-component regulatory system.

artículo científico publicado en 2003

Single-cell Gene Expression Profiling Using FACS and qPCR with Internal Standards.

artículo científico publicado en 2017

Stimulus-dependent dynamics of p53 in single cells

artículo científico publicado en 2011

Suppressing variation in synthetic circuits

artículo científico publicado en 2011

The Escherichia coli CpxA-CpxR envelope stress response system regulates expression of the porins ompF and ompC.

artículo científico publicado en 2005

The ups and downs of p53: understanding protein dynamics in single cells

artículo científico publicado en 2009

Tuning of mRNA stability through altering 3'-UTR sequences generates distinct output expression in a synthetic circuit driven by p53 oscillations

Using computational modeling and experimental synthetic perturbations to probe biological circuits

artículo científico publicado en 2015

p53 Pulses Diversify Target Gene Expression Dynamics in an mRNA Half-Life-Dependent Manner and Delineate Co-regulated Target Gene Subnetworks.

artículo científico publicado en 2016

p53 dynamics control cell fate

artículo científico publicado en 2012

p53 pulse modulation differentially regulates target gene promoters to regulate cell fate decisions

scientific article published on 01 September 2019