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Lista de obras de Clara Nervi

A highly specific q-RT-PCR assay to address the relevance of the JAK2WT and JAK2V617F expression levels and control genes in Ph-negative myeloproliferative neoplasms

artículo científico publicado en 2013

A minicircuitry comprised of microRNA-223 and transcription factors NFI-A and C/EBPalpha regulates human granulopoiesis

artículo científico publicado en 2005

A novel epigenetic AML1-ETO/THAP10/miR-383 mini-circuitry contributes to t(8;21) leukaemogenesis

artículo científico publicado en 2017

A transcriptome-wide approach reveals the key contribution of NFI-A in promoting erythroid differentiation of human CD34(+) progenitors and CML cells.

artículo científico publicado en 2010

ACTH 1-17 effects in acute myeloid leukemia

scientific article published on 01 April 1984

AML1-ETO triggers epigenetic activation of early growth response gene l, inducing apoptosis in t(8;21) acute myeloid leukemia

artículo científico publicado en 2014

AML1/ETO cooperates with HIF1α to promote leukemogenesis through DNMT3a transactivation.

artículo científico publicado en 2015

Acute promyelocytic leukemia: a curable disease.

artículo científico publicado en 1998

Alterations in expression, binding to ligand and DNA, and transcriptional activity of rearranged and wild-type retinoid receptors in retinoid-resistant acute promyelocytic leukemia cell lines.

artículo científico publicado en 1996

Argonaute 2 sustains the gene expression program driving human monocytic differentiation of acute myeloid leukemia cells.

artículo científico publicado en 2013

Caspases mediate retinoic acid-induced degradation of the acute promyelocytic leukemia PML/RARalpha fusion protein

artículo científico publicado el 1 de octubre de 1998

Characterization of the PML-RAR alpha chimeric product of the acute promyelocytic leukemia-specific t(15;17) translocation

artículo científico publicado el 1 de julio de 1992

Characterization of the retinoid binding properties of the major fusion products present in acute promyelocytic leukemia cells

artículo científico publicado en 1997

Complete remission through blast cell differentiation in PLZF/RARalpha-positive acute promyelocytic leukemia: in vitro and in vivo studies

artículo científico publicado en 2002

Control of squamous differentiation in tracheobronchial and epidermal epithelial cells: role of retinoids

artículo científico publicado el 1 de enero de 1992

Dielectric spectroscopy of blood cells suspensions: study on geometrical structure of biological cells.

artículo científico publicado en 2006

Down-stream regions of the POZ-domain influence the interaction of the t(11;17)-associated PLZF/RARalpha fusion protein with the histone-deacetylase recruiting co-repressor complex.

artículo científico publicado en 2001

Epigenetic plasticity of chromatin in embryonic and hematopoietic stem/progenitor cells: therapeutic potential of cell reprogramming.

artículo científico publicado en 2008

Epigenetic reprogramming of breast cancer cells by valproic acid occurs regardless of estrogen receptor status.

artículo científico publicado en 2008

Epigenetic role of miRNAs in normal and leukemic hematopoiesis

artículo científico publicado en 2013

Epigenetic silencing of the myelopoiesis regulator microRNA-223 by the AML1/ETO oncoprotein.

artículo científico publicado en 2007

Epigenetic treatment of solid tumours: a review of clinical trials

artículo científico publicado en 2015

Epigenetics in focus: pathogenesis of myelodysplastic syndromes and the role of hypomethylating agents.

artículo científico

Estrogen receptor expression activates the transcriptional and growth-inhibitory response to retinoids without enhanced retinoic acid receptor alpha expression.

artículo científico publicado en 1998

Expression of SMRTbeta promotes ligand-induced activation of mutated and wild-type retinoid receptors.

artículo científico publicado en 2004

Expression of nuclear retinoic acid receptors in normal tracheobronchial cells and in lung carcinoma cells

artículo científico publicado en 1991

Expression of nuclear retinoic acid receptors in wild-type and mutant embryonal carcinoma PCC4.aza1R cells

artículo científico publicado en 1990

Fusion proteins of the retinoic acid receptor-alpha recruit histone deacetylase in promyelocytic leukaemia

artículo científico publicado en 1998

Heterochromatic gene repression of the retinoic acid pathway in acute myeloid leukemia

article

Histone deacetylase inhibitor valproic acid enhances the cytokine-induced expansion of human hematopoietic stem cells.

artículo científico publicado en 2005

Homeobox 1.3 expression: induction by retinoic acid in human bronchial fibroblasts.

artículo científico publicado en 1992

Hyperplasia and squamous metaplasia in the tracheobronchial epithelium: alterations in the balance of growth and differentiation factors

artículo científico publicado el 1 de enero de 1992

Increased cholesterol sulfate and cholesterol sulfotransferase activity in relation to the multi-step process of differentiation in human epidermal keratinocytes.

artículo científico publicado en 1989

Inhibitors of histone deacetylases induce tumor-selective apoptosis through activation of the death receptor pathway

artículo científico publicado en 2004

Isolation and binding characteristics of nuclear retinoic acid receptors

scientific article published on 01 January 1990

MBD3, a component of the NuRD complex, facilitates chromatin alteration and deposition of epigenetic marks.

artículo científico publicado en 2008

Methyltransferase recruitment and DNA hypermethylation of target promoters by an oncogenic transcription factor

artículo científico publicado en 2002

MicroRNA: basic mechanisms and transcriptional regulatory networks for cell fate determination

artículo científico publicado en 2008

Molecular signature of retinoic acid treatment in acute promyelocytic leukemia

artículo científico publicado en 2005

Myc-binding-site recognition in the human genome is determined by chromatin context

artículo científico

NFI-A directs the fate of hematopoietic progenitors to the erythroid or granulocytic lineage and controls beta-globin and G-CSF receptor expression.

artículo científico publicado en 2009

Occurrence of resistance to retinoic acid in the acute promyelocytic leukemia cell line NB4 is associated with altered expression of the pml/RAR alpha protein.

artículo científico publicado en 1993

Oligomerization of RAR and AML1 transcription factors as a novel mechanism of oncogenic activation.

artículo científico publicado en 2000

Opposite effects of the acute promyelocytic leukemia PML-retinoic acid receptor alpha (RAR alpha) and PLZF-RAR alpha fusion proteins on retinoic acid signalling.

artículo científico publicado en 1997

PML nuclear body disruption impairs DNA double-strand break sensing and repair in APL.

artículo científico publicado en 2016

Polycombs and microRNA-223 regulate human granulopoiesis by transcriptional control of target gene expression.

artículo científico publicado en 2012

Proliferating and quiescent cells exhibit different subcellular distribution of protein kinase C activity

scientific article published on 01 January 1986

Protein kinase C in cell proliferation and differentiation

scientific article published on 01 January 1988

RARs and microRNAs.

artículo científico

Regulation of type I and type II transglutaminase in normal human bronchial epithelial and lung carcinoma cells

artículo científico publicado en 1992

Retinoic acid receptors: from molecular mechanisms to cancer therapy

artículo científico publicado en 2014

Retinoic acid targets DNA-methyltransferases and histone deacetylases during APL blast differentiation in vitro and in vivo.

artículo científico publicado en 2005

Retinoid antagonism of estrogen-responsive transforming growth factor alpha and pS2 gene expression in breast carcinoma cells

artículo científico publicado el 15 de julio de 1992

Sequential valproic acid/all-trans retinoic acid treatment reprograms differentiation in refractory and high-risk acute myeloid leukemia

scientific article published on 01 September 2006

Stage-specific modulation of skeletal myogenesis by inhibitors of nuclear deacetylases.

artículo científico publicado en 2002

Targeting fusion protein/corepressor contact restores differentiation response in leukemia cells.

artículo científico publicado en 2005

Targeting of the N-terminal coiled coil oligomerization interface by a helix-2 peptide inhibits unmutated and imatinib-resistant BCR/ABL.

artículo científico publicado en 2008

The 12th international conference on differentiation therapy: targeting the aberrant growth, differentiation and cell death programs of cancer cells

artículo científico publicado el 7 de enero de 2011

The integrity of the charged pocket in the BTB/POZ domain is essential for the phenotype induced by the leukemia-associated t(11;17) fusion protein PLZF/RARalpha.

artículo científico publicado en 2005

Transcriptional fine-tuning of microRNA-223 levels directs lineage choice of human hematopoietic progenitors.

artículo científico publicado en 2013

Transcriptional targeting by microRNA-polycomb complexes: a novel route in cell fate determination.

artículo científico publicado en 2012

Valproic acid defines a novel class of HDAC inhibitors inducing differentiation of transformed cells

artículo científico publicado en 2001

Vasopressin and insulin-like growth factors synergistically induce myogenesis in serum-free medium

artículo científico publicado el 1 de febrero de 1998

Vasopressin-dependent myogenic cell differentiation is mediated by both Ca2+/calmodulin-dependent kinase and calcineurin pathways

artículo científico publicado en 2005