Lista de obras - Luis Rivas - Dominio Público Uruguay

A BODIPY-embedding miltefosine analog linked to cell-penetrating Tat(48-60) peptide favors intracellular delivery and visualization of the antiparasitic drug

artículo científico publicado en 2014

A Multiplatform Metabolomic Approach to the Basis of Antimonial Action and Resistance in Leishmania infantum

artículo científico publicado en 2015

A Synthetic Strategy for Conjugation of Paromomycin to Cell-Penetrating Tat(48-60) for Delivery and Visualization into Leishmania Parasites

artículo científico publicado en 2017

A cutaneous gene therapy approach to treat infection through keratinocyte-targeted overexpression of antimicrobial peptides

artículo científico publicado en 2004

AM3 modulates dendritic cell pathogen recognition capabilities by targeting DC-SIGN.

artículo científico publicado en 2007

Acidic pH stress induces protein tyrosine phosphorylation in Leishmania pifanoi

artículo científico publicado en 1997

Activities of polymyxin B and cecropin A-,melittin peptide CA(1-8)M(1-18) against a multiresistant strain of Acinetobacter baumannii

artículo científico publicado en 2002

Activity of cecropin A-melittin hybrid peptides against colistin-resistant clinical strains of Acinetobacter baumannii: molecular basis for the differential mechanisms of action

artículo científico publicado en 2006

Amphibian antimicrobial peptides and Protozoa: lessons from parasites

artículo científico publicado en 2008

Antimicrobial peptide action on parasites.

artículo científico publicado en 2012

Appraisal of a Leishmania major strain stably expressing mCherry fluorescent protein for both in vitro and in vivo studies of potential drugs and vaccine against cutaneous leishmaniasis

artículo científico publicado en 2012

Biochemical characterization of the protective membrane glycoprotein GP46/M-2 of Leishmania amazonensis

artículo científico publicado en 1991

CE-ESI-MS metabolic fingerprinting of Leishmania resistance to antimony treatment.

artículo científico publicado en 2012

Cecropin‚Äìmelittin hybrid peptides as versatile templates in the development of membrane-active antibiotic agents1

article

Chapter 13. The Physical Matrix of the Plasma Membrane as a Target: The Charm of Drugs with Low Specificity

scholarly article

Characterization of Developmentally Regulated Molecules of Leishmania

Characterization of the leishmanicidal activity of antimicrobial peptides

artículo científico publicado en 2010

Chemistry and Applications of Synthetic Antimicrobial Peptides

Co-infection with HIV

article

Conjugation of quinones with natural polyamines: toward an expanded antitrypanosomatid profile

artículo científico publicado en 2012

Cyclobenzaprine Raises ROS Levels in Leishmania infantum and Reduces Parasite Burden in Infected Mice.

artículo científico publicado en 2017

Cytokines and infectious diseases

scientific article published on 01 February 1997

Defeating Leishmania resistance to Miltefosine (hexadecylphosphocholine) by peptide-mediated drug smuggling: A proof of mechanism for trypanosomatid chemotherapy

Dendritic cell (DC)-specific intercellular adhesion molecule 3 (ICAM-3)-grabbing nonintegrin (DC-SIGN, CD209), a C-type surface lectin in human DCs, is a receptor for Leishmania amastigotes.

artículo científico publicado en 2002

Design of Bactericidal Peptides Against Escherichia coli O157:H7, Pseudomonas aeruginosa and methicillin-resistant Staphylococcus aureus

artículo científico publicado en 2018

Developmental life cycle of Leishmania--cultivation and characterization of cultured extracellular amastigotes.

artículo científico publicado en 1993

Different Mutations in a P-type ATPase Transporter in Leishmania Parasites are Associated with Cross-resistance to Two Leading Drugs by Distinct Mechanisms

artículo científico publicado en 2016

Drug repurposing for Molecular basis of the leishmanicidal activity of the antidepressant sertraline

scientific article published in 2018

Effect of natural L- to D-amino acid conversion on the organization, membrane binding, and biological function of the antimicrobial peptides bombinins H.

artículo científico publicado en 2006

Effect of substituents in the A and B rings of chalcones on antiparasite activity

artículo científico publicado en 2020

Efficacy of cecropin A-melittin peptides on a sepsis model of infection by pan-resistant Acinetobacter baumannii

article

Enhanced leishmanicidal activity of cryptopeptide chimeras from the active N1 domain of bovine lactoferrin

artículo científico publicado en 2012

Enterocin AS-48 as Evidence for the Use of Bacteriocins as New Leishmanicidal Agents

artículo científico publicado en 2017

Erratum to “Interaction studies of diacyl glycerol arginine-based surfactants with DPPC and DMPC monolayers, relation with antimicrobial activity” [Colloids Surf. A: Physicochem. Eng. Aspects 319 (2008) 196–203]

scholarly article published in Colloids and Surfaces A

Eukaryotic antibiotic peptides: not only a membrane business

artículo científico publicado en 1999

Evidence for common antigens on human non-adherent synoviocytes (type A) and peripheral monocytes.

artículo científico publicado en 1986

Expression and regulation of mitochondrial uncoupling protein 1 from brown adipose tissue in Leishmania major promastigotes

artículo científico publicado en 1998

Fluorescent labeling of Acanthamoeba assessed in situ from corneal sectioned microscopy.

artículo científico publicado en 2012

Fungus-elicited metabolites from plants as an enriched source for new leishmanicidal agents: antifungal phenyl-phenalenone phytoalexins from the banana plant (Musa acuminata) target mitochondria of Leishmania donovani promastigotes

artículo científico publicado en 2004

Genomic Appraisal of the Multifactorial Basis for In Vitro Acquisition of Miltefosine Resistance in Leishmania donovani

artículo científico publicado en 2016

Human antimicrobial peptide histatin 5 is a cell-penetrating peptide targeting mitochondrial ATP synthesis in Leishmania

artículo científico publicado en 2008

Identification of new leishmanicidal peptide lead structures by automated real-time monitoring of changes in intracellular ATP.

artículo científico publicado en 2003

Impaired virulence and in vivo fitness of colistin-resistant Acinetobacter baumannii.

artículo científico publicado en 2011

In vitro bactericidal activity of the antiprotozoal drug miltefosine against Streptococcus pneumoniae and other pathogenic streptococci

artículo científico publicado en 2007

Influence of lysine N(ε)-trimethylation and lipid composition on the membrane activity of the cecropin A-melittin hybrid peptide CA(1-7)M(2-9).

artículo científico publicado en 2010

Interaction studies of diacyl glycerol arginine-based surfactants with DPPC and DMPC monolayers, relation with antimicrobial activity

Kahalalide F, an antitumor depsipeptide in clinical trials, and its analogues as effective antileishmanial agents

artículo científico publicado en 2009

Leishmania donovani: thionins, plant antimicrobial peptides with leishmanicidal activity

artículo científico publicado en 2009

Leishmania infantum modulates host macrophage mitochondrial metabolism by hijacking the SIRT1-AMPK axis

artículo científico publicado en 2015

Lysine N(epsilon)-trimethylation, a tool for improving the selectivity of antimicrobial peptides

artículo científico publicado en 2010

Lytic cell death induced by melittin bypasses pyroptosis but induces NLRP3 inflammasome activation and IL-1β release.

artículo científico publicado en 2017

Mechanisms of action of substituted β-amino alkanols on Leishmania donovani.

artículo científico publicado en 2014

Membrane-active peptides as anti-infectious agents

article published in 2010

Miltefosine (hexadecylphosphocholine) inhibits cytochrome c oxidase in Leishmania donovani promastigotes

artículo científico publicado en 2007

Molecular Basis of the Leishmanicidal Activity of the Antidepressant Sertraline as a Drug Repurposing Candidate

scholarly article by Marta L. Lima et al published 8 October 2018 in Antimicrobial Agents and Chemotherapy

Multi-analytical platform metabolomic approach to study miltefosine mechanism of action and resistance in Leishmania

artículo científico publicado en 2014

New benzophenone-derived bisphosphonium salts as leishmanicidal leads targeting mitochondria through inhibition of respiratory complex II.

artículo científico publicado en 2010

Partial characterization of membrane-associated proteinases from Micrococcus lysodeikticus

artículo científico publicado en 1982

Permeabilization of the Mitochondrial Inner Membrane by Short Cecropin-A-Melittin Hybrid Peptides

artículo científico publicado en 1994

Phosphorylation of the N-terminal and C-terminal CD3-epsilon-ITAM tyrosines is differentially regulated in T cells

artículo científico publicado en 2002

Platelet-Activating Factor Receptor Contributes to Antileishmanial Function of Miltefosine

artículo científico publicado en 2015

Péptidos antibióticos eucarióticos: ¿una nueva alternativa en clínica?

Recombinant vs native Anisakis haemoglobin (Ani s 13): Its appraisal as a new gold standard for the diagnosis of allergy

artículo científico publicado en 2017

Regulated expression of the pathogen receptor dendritic cell-specific intercellular adhesion molecule 3 (ICAM-3)-grabbing nonintegrin in THP-1 human leukemic cells, monocytes, and macrophages.

artículo científico publicado en 2004

Release of Lipid Vesicle Contents by an Antibacterial Cecropin A−Melittin Hybrid Peptide†

scientific article published on 01 July 1996

Riboflavin derivatives for enhanced photodynamic activity against Leishmania parasites

Role of positional hydrophobicity in the leishmanicidal activity of magainin 2.

artículo científico publicado en 2004

Role of the C-type lectins DC-SIGN and L-SIGN in Leishmania interaction with host phagocytes.

artículo científico publicado en 2005

Safety and efficacy of antimicrobial peptides against naturally acquired leishmaniasis.

artículo científico publicado en 2004

Sequence inversion and phenylalanine surrogates at the beta-turn enhance the antibiotic activity of gramicidin S.

artículo científico publicado en 2010

Solid-phase synthesis of the cyclic lipononadepsipeptide [N-Mst(Ser1), d-Ser4, L-Thr6, L-Asp8, L-Thr9]syringotoxin.

artículo científico publicado en 2003

Structural Framework for the Modulation of the Activity of the Hybrid Antibiotic Peptide Cecropin A-Melittin [CA(1-7)M(2-9)] by Nε-Lysine Trimethylation

artículo científico publicado en 2011

Studies on the antimicrobial activity of cecropin A-melittin hybrid peptides in colistin-resistant clinical isolates of Acinetobacter baumannii

artículo científico publicado en 2006

Synthesis and biological evaluation of fluorescent leishmanicidal analogues of hexadecylphosphocholine (miltefosine) as probes of antiparasite mechanisms.

artículo científico publicado en 2007

Synthesis of 16-mercaptohexadecylphosphocholine, a miltefosine analog with leishmanicidal activity

scientific article published in 2006

Synthesis of BODIPY-labeled alkylphosphocholines with leishmanicidal activity, as fluorescent analogues of miltefosine

artículo científico publicado en 2008

Synthesis, biological assessment and molecular modeling of new dihydroquinoline-3-carboxamides and dihydroquinoline-3-carbohydrazide derivatives as cholinesterase inhibitors, and Ca channel antagonists

scientific article published on 15 December 2010

Synthetic peptides representing the N-terminal segment of surfactant protein C modulate LPS-stimulated TNF-alpha production by macrophages

artículo científico publicado en 2009

Tafenoquine, an antiplasmodial 8-aminoquinoline, targets leishmania respiratory complex III and induces apoptosis

artículo científico publicado en 2010

Temporins, small antimicrobial peptides with leishmanicidal activity.

artículo científico publicado en 2004

The 8-aminoquinoline analogue sitamaquine causes oxidative stress in Leishmania donovani promastigotes by targeting succinate dehydrogenase

artículo científico publicado en 2011

The N-terminal segment of pulmonary surfactant lipopeptide SP-C has intrinsic propensity to interact with and perturb phospholipid bilayers

artículo científico publicado en 2004

The antenna system of Rhodospirillum rubrum. Detection of macromolecular constituents not stainable by Coomassie brilliant blue in solubilized preparations of the B880 complex

artículo científico publicado en 1985

The antitumoral depsipeptide IB-01212 kills Leishmania through an apoptosis-like process involving intracellular targets

artículo científico publicado en 2010

The biosynthesis, processing, and immunolocalization of Leishmania pifanoi amastigote cysteine proteinases

scientific article published on 01 November 1994

The cost of resistance to colistin in Acinetobacter baumannii: a proteomic perspective

artículo científico publicado en 2009

The induction of NOS2 expression by the hybrid cecropin A-melittin antibiotic peptide CA(1-8)M(1-18) in the monocytic line RAW 264.7 is triggered by a temporary and reversible plasma membrane permeation

artículo científico publicado en 2005

Therapeutic index of gramicidin S is strongly modulated by D-phenylalanine analogues at the beta-turn

artículo científico publicado en 2009

Topography of the subunits of Micrococcus lysodeikticus F1-ATPase

scientific article published on 01 January 1983

Towards discovery of new leishmanicidal scaffolds able to inhibit Leishmania GSK-3

scientific article published on 01 December 2020

Untargeted metabolomic analysis of miltefosine action in Leishmania infantum reveals changes to the internal lipid metabolism

artículo científico publicado en 2013

Virulence and disease in leishmaniasis: what is relevant for the patient?

artículo científico publicado en 2004

Widening the antimicrobial spectrum of esters of bicyclic amines: In vitro effect on gram-positive Streptococcus pneumoniae and gram-negative non-typeable Haemophilus influenzae biofilms

scholarly article by Emma Roig-Molina published in January 2019

Lista de obras de Luis Rivas

A BODIPY-embedding miltefosine analog linked to cell-penetrating Tat(48-60) peptide favors intracellular delivery and visualization of the antiparasitic drug

A Multiplatform Metabolomic Approach to the Basis of Antimonial Action and Resistance in Leishmania infantum

A Synthetic Strategy for Conjugation of Paromomycin to Cell-Penetrating Tat(48-60) for Delivery and Visualization into Leishmania Parasites

A cutaneous gene therapy approach to treat infection through keratinocyte-targeted overexpression of antimicrobial peptides

AM3 modulates dendritic cell pathogen recognition capabilities by targeting DC-SIGN.

Acidic pH stress induces protein tyrosine phosphorylation in Leishmania pifanoi

Activities of polymyxin B and cecropin A-,melittin peptide CA(1-8)M(1-18) against a multiresistant strain of Acinetobacter baumannii

Activity of cecropin A-melittin hybrid peptides against colistin-resistant clinical strains of Acinetobacter baumannii: molecular basis for the differential mechanisms of action

Amphibian antimicrobial peptides and Protozoa: lessons from parasites

Antimicrobial peptide action on parasites.

Appraisal of a Leishmania major strain stably expressing mCherry fluorescent protein for both in vitro and in vivo studies of potential drugs and vaccine against cutaneous leishmaniasis

Biochemical characterization of the protective membrane glycoprotein GP46/M-2 of Leishmania amazonensis

CE-ESI-MS metabolic fingerprinting of Leishmania resistance to antimony treatment.

Cecropin‚Äìmelittin hybrid peptides as versatile templates in the development of membrane-active antibiotic agents1

Chapter 13. The Physical Matrix of the Plasma Membrane as a Target: The Charm of Drugs with Low Specificity

Characterization of Developmentally Regulated Molecules of Leishmania

Characterization of the leishmanicidal activity of antimicrobial peptides

Chemistry and Applications of Synthetic Antimicrobial Peptides

Co-infection with HIV

Conjugation of quinones with natural polyamines: toward an expanded antitrypanosomatid profile

Cyclobenzaprine Raises ROS Levels in Leishmania infantum and Reduces Parasite Burden in Infected Mice.

Cytokines and infectious diseases

Defeating Leishmania resistance to Miltefosine (hexadecylphosphocholine) by peptide-mediated drug smuggling: A proof of mechanism for trypanosomatid chemotherapy

Dendritic cell (DC)-specific intercellular adhesion molecule 3 (ICAM-3)-grabbing nonintegrin (DC-SIGN, CD209), a C-type surface lectin in human DCs, is a receptor for Leishmania amastigotes.

Design of Bactericidal Peptides Against Escherichia coli O157:H7, Pseudomonas aeruginosa and methicillin-resistant Staphylococcus aureus

Developmental life cycle of Leishmania--cultivation and characterization of cultured extracellular amastigotes.

Different Mutations in a P-type ATPase Transporter in Leishmania Parasites are Associated with Cross-resistance to Two Leading Drugs by Distinct Mechanisms

Drug repurposing for Molecular basis of the leishmanicidal activity of the antidepressant sertraline

Effect of natural L- to D-amino acid conversion on the organization, membrane binding, and biological function of the antimicrobial peptides bombinins H.

Effect of substituents in the A and B rings of chalcones on antiparasite activity

Efficacy of cecropin A-melittin peptides on a sepsis model of infection by pan-resistant Acinetobacter baumannii

Enhanced leishmanicidal activity of cryptopeptide chimeras from the active N1 domain of bovine lactoferrin

Enterocin AS-48 as Evidence for the Use of Bacteriocins as New Leishmanicidal Agents

Erratum to “Interaction studies of diacyl glycerol arginine-based surfactants with DPPC and DMPC monolayers, relation with antimicrobial activity” [Colloids Surf. A: Physicochem. Eng. Aspects 319 (2008) 196–203]

Eukaryotic antibiotic peptides: not only a membrane business

Evidence for common antigens on human non-adherent synoviocytes (type A) and peripheral monocytes.

Expression and regulation of mitochondrial uncoupling protein 1 from brown adipose tissue in Leishmania major promastigotes

Fluorescent labeling of Acanthamoeba assessed in situ from corneal sectioned microscopy.

Fungus-elicited metabolites from plants as an enriched source for new leishmanicidal agents: antifungal phenyl-phenalenone phytoalexins from the banana plant (Musa acuminata) target mitochondria of Leishmania donovani promastigotes

Genomic Appraisal of the Multifactorial Basis for In Vitro Acquisition of Miltefosine Resistance in Leishmania donovani

Human antimicrobial peptide histatin 5 is a cell-penetrating peptide targeting mitochondrial ATP synthesis in Leishmania

Identification of new leishmanicidal peptide lead structures by automated real-time monitoring of changes in intracellular ATP.

Impaired virulence and in vivo fitness of colistin-resistant Acinetobacter baumannii.

In vitro bactericidal activity of the antiprotozoal drug miltefosine against Streptococcus pneumoniae and other pathogenic streptococci

Influence of lysine N(ε)-trimethylation and lipid composition on the membrane activity of the cecropin A-melittin hybrid peptide CA(1-7)M(2-9).

Interaction studies of diacyl glycerol arginine-based surfactants with DPPC and DMPC monolayers, relation with antimicrobial activity

Kahalalide F, an antitumor depsipeptide in clinical trials, and its analogues as effective antileishmanial agents

Leishmania donovani: thionins, plant antimicrobial peptides with leishmanicidal activity

Leishmania infantum modulates host macrophage mitochondrial metabolism by hijacking the SIRT1-AMPK axis

Lysine N(epsilon)-trimethylation, a tool for improving the selectivity of antimicrobial peptides

Lytic cell death induced by melittin bypasses pyroptosis but induces NLRP3 inflammasome activation and IL-1β release.

Mechanisms of action of substituted β-amino alkanols on Leishmania donovani.

Membrane-active peptides as anti-infectious agents

Miltefosine (hexadecylphosphocholine) inhibits cytochrome c oxidase in Leishmania donovani promastigotes

Molecular Basis of the Leishmanicidal Activity of the Antidepressant Sertraline as a Drug Repurposing Candidate

Multi-analytical platform metabolomic approach to study miltefosine mechanism of action and resistance in Leishmania

New benzophenone-derived bisphosphonium salts as leishmanicidal leads targeting mitochondria through inhibition of respiratory complex II.

Partial characterization of membrane-associated proteinases from Micrococcus lysodeikticus

Permeabilization of the Mitochondrial Inner Membrane by Short Cecropin-A-Melittin Hybrid Peptides

Phosphorylation of the N-terminal and C-terminal CD3-epsilon-ITAM tyrosines is differentially regulated in T cells

Platelet-Activating Factor Receptor Contributes to Antileishmanial Function of Miltefosine

Péptidos antibióticos eucarióticos: ¿una nueva alternativa en clínica?

Recombinant vs native Anisakis haemoglobin (Ani s 13): Its appraisal as a new gold standard for the diagnosis of allergy

Regulated expression of the pathogen receptor dendritic cell-specific intercellular adhesion molecule 3 (ICAM-3)-grabbing nonintegrin in THP-1 human leukemic cells, monocytes, and macrophages.

Release of Lipid Vesicle Contents by an Antibacterial Cecropin A−Melittin Hybrid Peptide†

Riboflavin derivatives for enhanced photodynamic activity against Leishmania parasites

Role of positional hydrophobicity in the leishmanicidal activity of magainin 2.

Role of the C-type lectins DC-SIGN and L-SIGN in Leishmania interaction with host phagocytes.

Safety and efficacy of antimicrobial peptides against naturally acquired leishmaniasis.

Sequence inversion and phenylalanine surrogates at the beta-turn enhance the antibiotic activity of gramicidin S.

Solid-phase synthesis of the cyclic lipononadepsipeptide [N-Mst(Ser1), d-Ser4, L-Thr6, L-Asp8, L-Thr9]syringotoxin.

Structural Framework for the Modulation of the Activity of the Hybrid Antibiotic Peptide Cecropin A-Melittin [CA(1-7)M(2-9)] by Nε-Lysine Trimethylation

Studies on the antimicrobial activity of cecropin A-melittin hybrid peptides in colistin-resistant clinical isolates of Acinetobacter baumannii

Synthesis and biological evaluation of fluorescent leishmanicidal analogues of hexadecylphosphocholine (miltefosine) as probes of antiparasite mechanisms.

Synthesis of 16-mercaptohexadecylphosphocholine, a miltefosine analog with leishmanicidal activity

Synthesis of BODIPY-labeled alkylphosphocholines with leishmanicidal activity, as fluorescent analogues of miltefosine

Synthesis, biological assessment and molecular modeling of new dihydroquinoline-3-carboxamides and dihydroquinoline-3-carbohydrazide derivatives as cholinesterase inhibitors, and Ca channel antagonists

Synthetic peptides representing the N-terminal segment of surfactant protein C modulate LPS-stimulated TNF-alpha production by macrophages

Tafenoquine, an antiplasmodial 8-aminoquinoline, targets leishmania respiratory complex III and induces apoptosis