Lista de obras - Julhash U Kazi - Dominio Público Uruguay

ABL2 suppresses FLT3-ITD-induced cell proliferation through negative regulation of AKT signaling.

artículo científico publicado en 2017

Aberrant activation of the PI3K/mTOR pathway promotes resistance to sorafenib in AML.

artículo científico

Acute leukemia cells resistant to PI3K/mTOR inhibition display upregulation of P2RY14 expression.

artículo científico publicado en 2018

BEX1 acts as a tumor suppressor in acute myeloid leukemia.

artículo científico

Bioinformatic prediction and analysis of eukaryotic protein kinases in the rat genome

scientific article published on 14 December 2007

Brain-Expressed X-linked (BEX) proteins in human cancers.

artículo científico

Bruton's tyrosine kinase potentiates ALK signaling and serves as a potential therapeutic target of neuroblastoma

scientific article published on 16 July 2018

Celecoxib-induced growth inhibition in SW480 colon cancer cells is associated with activation of protein kinase G.

artículo científico publicado en 2008

Comparative analysis of human and bovine protein kinases reveals unique relationship and functional diversity

artículo científico publicado en 2011

Correction: The ALK inhibitor AZD3463 effectively inhibits growth of sorafenib-resistant acute myeloid leukemia

artículo científico publicado en 2019

De novo activating mutations drive clonal evolution and enhance clonal fitness in KMT2A-rearranged leukemia

artículo científico publicado en 2018

Deregulation of protein phosphatase expression in acute myeloid leukemia ⬇️

artículo científico publicado el 26 de febrero de 2013

Efficacy of the CDK inhibitor dinaciclib in vitro and in vivo in T-cell acute lymphoblastic leukemia.

artículo científico publicado en 2017

Expression of GADS enhances FLT3-induced mitogenic signaling.

artículo científico publicado en 2016

FLT3 mutations in patients with childhood acute lymphoblastic leukemia (ALL).

artículo científico publicado en 2013

FLT3 signals via the adapter protein Grb10 and overexpression of Grb10 leads to aberrant cell proliferation in acute myeloid leukemia

artículo científico publicado en 2012

FMS-like Tyrosine Kinase 3/FLT3: From Basic Science to Clinical Implications

scientific article published on 01 July 2019

FYN expression potentiates FLT3-ITD induced STAT5 signaling in acute myeloid leukemia.

artículo científico publicado en 2016

Germline mutations of KIT in gastrointestinal stromal tumor (GIST) and mastocytosis

artículo científico publicado en 2016

Glucocorticoid-resistant B cell acute lymphoblastic leukemia displays receptor tyrosine kinase activation

artículo científico publicado en 2019

Grb10 is a dual regulator of receptor tyrosine kinase signaling

artículo científico publicado en 2014

HIF2α contributes to antiestrogen resistance via positive bilateral crosstalk with EGFR in breast cancer cells.

artículo científico publicado en 2016

Induction of the nuclear proto-oncogene c-fos by the phorbol ester TPA and v-H-Ras.

artículo científico publicado en 2008

Isoform-specific translocation of PKC isoforms in NIH3T3 cells by TPA.

artículo científico publicado en 2007

KITD816V Induces SRC-Mediated Tyrosine Phosphorylation of MITF and Altered Transcription Program in Melanoma

artículo científico publicado en 2017

Keratin 19 expression correlates with poor prognosis in breast cancer

artículo científico publicado en 2014

Maximum likelihood analysis of mammalian p53 indicates the presence of positively selected sites and higher tumorigenic mutations in purifying sites.

artículo científico publicado en 2011

Mechanisms of Anticancer Therapy Resistance: The Role of Cancer Stem Cells

artículo científico publicado en 2020

Metallopeptidase inhibitor 1 (TIMP-1) promotes receptor tyrosine kinase c-Kit signaling in colorectal cancer

artículo científico publicado en 2019

PI3 kinase is indispensable for oncogenic transformation by the V560D mutant of c-Kit in a kinase-independent manner

artículo científico publicado en 2015

Phosphorylation of the activation loop tyrosine 823 in c-Kit is crucial for cell survival and proliferation.

artículo científico publicado en 2013

Protein kinase C (PKC) as a drug target in chronic lymphocytic leukemia.

artículo científico publicado en 2013

Protein kinase C expression is deregulated in chronic lymphocytic leukemia.

artículo científico publicado en 2013

Role of SRC-like adaptor protein (SLAP) in immune and malignant cell signaling.

artículo científico publicado en 2015

SOCS proteins in regulation of receptor tyrosine kinase signaling

artículo científico

SOCS6 is a selective suppressor of receptor tyrosine kinase signaling

artículo científico publicado en 2014

SRC-like adaptor protein 2 (SLAP2) is a negative regulator of KIT-D816V-mediated oncogenic transformation

artículo científico publicado en 2018

SYK is a critical regulator of FLT3 in acute myeloid leukemia

artículo científico publicado en 2014

Selective mutation in ATP-binding site reduces affinity of drug to the kinase: a possible mechanism of chemo-resistance.

artículo científico publicado en 2013

Src-Like adaptor protein (SLAP) binds to the receptor tyrosine kinase Flt3 and modulates receptor stability and downstream signaling.

artículo científico publicado en 2012

Src-like adaptor protein 2 (SLAP2) binds to and inhibits FLT3 signaling

artículo científico publicado en 2016

Src-like-adaptor protein (SLAP) differentially regulates normal and oncogenic c-Kit signaling.

artículo científico publicado en 2013

Suppressor of cytokine signaling 2 (SOCS2) associates with FLT3 and negatively regulates downstream signaling ⬇️

artículo científico publicado el 19 de marzo de 2013

T-cell Acute Lymphoblastic Leukemia Cells Display Activation of Different Survival Pathways.

artículo científico publicado en 2017

The ALK inhibitor AZD3463 effectively inhibits growth of sorafenib-resistant acute myeloid leukemia

scholarly article by Sausan A Moharram et al published 15 January 2019 in Blood Cancer Journal

The PI3-kinase isoform p110δ is essential for cell transformation induced by the D816V mutant of c-Kit in a lipid-kinase-independent manner.

artículo científico publicado en 2013

The Phosphatases STS1 and STS2 Regulate Hematopoietic Stem and Progenitor Cell Fitness.

artículo científico publicado en 2015

The Src family kinase LCK cooperates with oncogenic FLT3/ITD in cellular transformation

artículo científico publicado en 2017

The activation loop tyrosine 823 is essential for the transforming capacity of the c-Kit oncogenic mutant D816V.

artículo científico publicado en 2014

The basic helix-loop-helix (bHLH) proteins in breast cancer progression ⬇️

artículo científico publicado el 23 de julio de 2013

The dual specificity PI3K/mTOR inhibitor PKI-587 displays efficacy against T-cell acute lymphoblastic leukemia (T-ALL).

artículo científico publicado en 2017

The presence or absence of IL-3 during long-term culture of Flt3-ITD and c-Kit-D816V expressing Ba/F3 cells influences signaling outcome.

artículo científico publicado en 2013

The role of HOXB2 and HOXB3 in acute myeloid leukemia.

artículo científico publicado en 2015

The role of SRC family kinases in FLT3 signaling

artículo científico publicado en 2018

The tyrosine kinase CSK associates with FLT3 and c-Kit receptors and regulates downstream signaling ⬇️

artículo científico publicado el 21 de mayo de 2013

Tyrosine 842 in the activation loop is required for full transformation by the oncogenic mutant FLT3-ITD.

artículo científico publicado en 2017

Lista de obras de Julhash U Kazi

ABL2 suppresses FLT3-ITD-induced cell proliferation through negative regulation of AKT signaling.

Aberrant activation of the PI3K/mTOR pathway promotes resistance to sorafenib in AML.

Acute leukemia cells resistant to PI3K/mTOR inhibition display upregulation of P2RY14 expression.

BEX1 acts as a tumor suppressor in acute myeloid leukemia.

Bioinformatic prediction and analysis of eukaryotic protein kinases in the rat genome

Brain-Expressed X-linked (BEX) proteins in human cancers.

Bruton's tyrosine kinase potentiates ALK signaling and serves as a potential therapeutic target of neuroblastoma

Celecoxib-induced growth inhibition in SW480 colon cancer cells is associated with activation of protein kinase G.

Comparative analysis of human and bovine protein kinases reveals unique relationship and functional diversity

Correction: The ALK inhibitor AZD3463 effectively inhibits growth of sorafenib-resistant acute myeloid leukemia

De novo activating mutations drive clonal evolution and enhance clonal fitness in KMT2A-rearranged leukemia

Deregulation of protein phosphatase expression in acute myeloid leukemia ⬇️

Efficacy of the CDK inhibitor dinaciclib in vitro and in vivo in T-cell acute lymphoblastic leukemia.

Expression of GADS enhances FLT3-induced mitogenic signaling.

FLT3 mutations in patients with childhood acute lymphoblastic leukemia (ALL).

FLT3 signals via the adapter protein Grb10 and overexpression of Grb10 leads to aberrant cell proliferation in acute myeloid leukemia

FMS-like Tyrosine Kinase 3/FLT3: From Basic Science to Clinical Implications

FYN expression potentiates FLT3-ITD induced STAT5 signaling in acute myeloid leukemia.

Germline mutations of KIT in gastrointestinal stromal tumor (GIST) and mastocytosis

Glucocorticoid-resistant B cell acute lymphoblastic leukemia displays receptor tyrosine kinase activation

Grb10 is a dual regulator of receptor tyrosine kinase signaling

HIF2α contributes to antiestrogen resistance via positive bilateral crosstalk with EGFR in breast cancer cells.

Induction of the nuclear proto-oncogene c-fos by the phorbol ester TPA and v-H-Ras.

Isoform-specific translocation of PKC isoforms in NIH3T3 cells by TPA.

KITD816V Induces SRC-Mediated Tyrosine Phosphorylation of MITF and Altered Transcription Program in Melanoma

Keratin 19 expression correlates with poor prognosis in breast cancer

Maximum likelihood analysis of mammalian p53 indicates the presence of positively selected sites and higher tumorigenic mutations in purifying sites.

Mechanisms of Anticancer Therapy Resistance: The Role of Cancer Stem Cells

Metallopeptidase inhibitor 1 (TIMP-1) promotes receptor tyrosine kinase c-Kit signaling in colorectal cancer

PI3 kinase is indispensable for oncogenic transformation by the V560D mutant of c-Kit in a kinase-independent manner

Phosphorylation of the activation loop tyrosine 823 in c-Kit is crucial for cell survival and proliferation.

Protein kinase C (PKC) as a drug target in chronic lymphocytic leukemia.

Protein kinase C expression is deregulated in chronic lymphocytic leukemia.

Role of SRC-like adaptor protein (SLAP) in immune and malignant cell signaling.

SOCS proteins in regulation of receptor tyrosine kinase signaling

SOCS6 is a selective suppressor of receptor tyrosine kinase signaling

SRC-like adaptor protein 2 (SLAP2) is a negative regulator of KIT-D816V-mediated oncogenic transformation

SYK is a critical regulator of FLT3 in acute myeloid leukemia

Selective mutation in ATP-binding site reduces affinity of drug to the kinase: a possible mechanism of chemo-resistance.

Src-Like adaptor protein (SLAP) binds to the receptor tyrosine kinase Flt3 and modulates receptor stability and downstream signaling.

Src-like adaptor protein 2 (SLAP2) binds to and inhibits FLT3 signaling

Src-like-adaptor protein (SLAP) differentially regulates normal and oncogenic c-Kit signaling.

Suppressor of cytokine signaling 2 (SOCS2) associates with FLT3 and negatively regulates downstream signaling ⬇️

T-cell Acute Lymphoblastic Leukemia Cells Display Activation of Different Survival Pathways.

The ALK inhibitor AZD3463 effectively inhibits growth of sorafenib-resistant acute myeloid leukemia

The PI3-kinase isoform p110δ is essential for cell transformation induced by the D816V mutant of c-Kit in a lipid-kinase-independent manner.

The Phosphatases STS1 and STS2 Regulate Hematopoietic Stem and Progenitor Cell Fitness.

The Src family kinase LCK cooperates with oncogenic FLT3/ITD in cellular transformation

The activation loop tyrosine 823 is essential for the transforming capacity of the c-Kit oncogenic mutant D816V.

The basic helix-loop-helix (bHLH) proteins in breast cancer progression ⬇️

The dual specificity PI3K/mTOR inhibitor PKI-587 displays efficacy against T-cell acute lymphoblastic leukemia (T-ALL).

The presence or absence of IL-3 during long-term culture of Flt3-ITD and c-Kit-D816V expressing Ba/F3 cells influences signaling outcome.

The role of HOXB2 and HOXB3 in acute myeloid leukemia.

The role of SRC family kinases in FLT3 signaling

The tyrosine kinase CSK associates with FLT3 and c-Kit receptors and regulates downstream signaling ⬇️

Tyrosine 842 in the activation loop is required for full transformation by the oncogenic mutant FLT3-ITD.