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"Fusion and fission" unveils remarkable insights into osteoclast plasticity

artículo científico publicado en 2012

A bioceramic with enhanced osteogenic properties to regulate the function of osteoblastic and osteocalastic cells for bone tissue regeneration.

artículo científico publicado en 2016

A highly sensitive prenylation assay reveals in vivo effects of bisphosphonate drug on the Rab prenylome of macrophages outside the skeleton

artículo científico publicado en 2015

A molecular code for endosomal recycling of phosphorylated cargos by the SNX27-retromer complex

artículo científico publicado en 2016

Alexidine Dihydrochloride Attenuates Osteoclast Formation and Bone Resorption and Protects Against LPS-Induced Osteolysis

artículo científico publicado en 2015

Bafilomycin A1 Attenuates Osteoclast Acidification and Formation, Accompanied by Increased Levels of SQSTM1/p62 Protein

artículo científico publicado en 2015

Brief exposure to full length parathyroid hormone-related protein (PTHrP) causes persistent generation of cyclic AMP through an endocytosis-dependent mechanism

scientific article published on 30 August 2019

Caffeic acid phenethyl ester, an active component of honeybee propolis attenuates osteoclastogenesis and bone resorption via the suppression of RANKL-induced NF-kappaB and NFAT activity.

artículo científico publicado en 2009

Calmodulin interacts with Rab3D and modulates osteoclastic bone resorption.

artículo científico publicado en 2016

Characterisation of genetic regulatory effects for osteoporosis risk variants in human osteoclasts

scientific article published on 26 March 2020

Choline kinase β mutant mice exhibit reduced phosphocholine, elevated osteoclast activity, and low bone mass

artículo científico publicado en 2014

Circulating Lipocalin 2 Levels Predict Fracture-Related Hospitalizations in Elderly Women: A Prospective Cohort Study

artículo científico publicado en 2015

Cyanidin Chloride inhibits ovariectomy-induced osteoporosis by suppressing RANKL-mediated osteoclastogenesis and associated signaling pathways

artículo científico publicado en 2017

Distinct yet overlapping roles of Rab GTPases on synaptic vesicles

artículo científico publicado el 1 de marzo de 2011

Disulfiram attenuates osteoclast differentiation in vitro: a potential antiresorptive agent

artículo científico publicado en 2015

EGFL6 promotes endothelial cell migration and angiogenesis through the activation of extracellular signal-regulated kinase.

artículo científico publicado en 2011

Evidence of reciprocal regulation between the high extracellular calcium and RANKL signal transduction pathways in RAW cell derived osteoclasts.

artículo científico publicado en 2005

Evidence that human cartilage and chondrocytes do not express calcitonin receptor.

artículo científico publicado en 2007

Expression Quantitative Trait Locus Study of Bone Mineral Density GWAS Variants in Human Osteoclasts

artículo científico publicado en 2018

Functional Assessment of Calcium-Sensing Receptor Variants Confirms Familial Hypocalciuric Hypercalcemia

artículo científico publicado en 2022

GPCR Signaling and Trafficking: The Long and Short of It.

artículo científico publicado en 2016

Genetic regulatory mechanisms in human osteoclasts suggest a role for the STMP1 and DCSTAMP genes in Paget's disease of bone

artículo científico publicado en 2019

Glucocorticoid impairs cell-cell communication by autophagy-mediated degradation of connexin 43 in osteocytes.

scientific article published on 27 April 2016

Identical subchondral bone microarchitecture pattern with increased bone resorption in rheumatoid arthritis as compared to osteoarthritis

artículo científico publicado en 2014

In vitro evaluation of natural marine sponge collagen as a scaffold for bone tissue engineering.

artículo científico publicado en 2011

Influence of age and gender on microarchitecture and bone remodeling in subchondral bone of the osteoarthritic femoral head.

artículo científico publicado en 2015

M-CSF potently augments RANKL-induced resorption activation in mature human osteoclasts

artículo científico publicado en 2011

Membrane trafficking in osteoclasts and implications for osteoporosis

scientific article published on 05 March 2019

Mutations of Vasopressin Receptor 2 Including Novel L312S Have Differential Effects on Trafficking.

artículo científico publicado en 2016

Mutations within the TNF-like core domain of RANKL impair osteoclast differentiation and activation

artículo científico publicado en 2008

Myocyte enhancer factor 2 and microphthalmia-associated transcription factor cooperate with NFATc1 to transactivate the V-ATPase d2 promoter during RANKL-induced osteoclastogenesis.

artículo científico publicado en 2009

Natural Germacrane Sesquiterpenes Inhibit Osteoclast Formation, Bone Resorption, RANKL-Induced NF-κB Activation, and IκBα Degradation.

artículo científico publicado en 2015

Osteoclasts recycle via osteomorphs during RANKL-stimulated bone resorption

artículo científico publicado en 2021

PLEKHM1/DEF8/RAB7 complex regulates lysosome positioning and bone homeostasis.

artículo científico publicado en 2016

Paclitaxel inhibits osteoclast formation and bone resorption via influencing mitotic cell cycle arrest and RANKL-induced activation of NF-κB and ERK.

artículo científico publicado en 2012

Parathyroid Hormone-Related Protein Negatively Regulates Tumor Cell Dormancy Genes in a PTHR1/Cyclic AMP-Independent Manner.

artículo científico publicado en 2018

Phosphorylation-regulated axonal dependent transport of syntaxin 1 is mediated by a Kinesin-1 adapter.

artículo científico publicado en 2012

Quantitative analysis of synaptic vesicle Rabs uncovers distinct yet overlapping roles for Rab3a and Rab27b in Ca2+-triggered exocytosis

artículo científico publicado en 2010

Quantitative comparison of glutamatergic and GABAergic synaptic vesicles unveils selectivity for few proteins including MAL2, a novel synaptic vesicle protein.

artículo científico publicado en 2010

Rab GTPases: Emerging Oncogenes and Tumor Suppressive Regulators for the Editing of Survival Pathways in Cancer

scientific article published on 21 January 2020

Rab3D regulates a novel vesicular trafficking pathway that is required for osteoclastic bone resorption

artículo científico publicado en 2005

Rheumatoid arthritis: pathological mechanisms and modern pharmacologic therapies

artículo científico publicado en 2018

SC-514, a selective inhibitor of IKKβ attenuates RANKL-induced osteoclastogenesis and NF-κB activation.

artículo científico publicado en 2013

Septins are critical regulators of osteoclastic bone resorption

artículo científico publicado en 2018

Sorting nexin 27 couples PTHR trafficking to retromer for signal regulation in osteoblasts during bone growth

artículo científico publicado en 2016

Staphylococcus aureus Infects Osteoclasts and Replicates Intracellularly

scientific article published on 15 October 2019

Subchondral bone in osteoarthritis: insight into risk factors and microstructural changes

artículo científico publicado en 2013

Targeted sequencing of in familial Paget's disease of bone

scientific article published on 21 February 2019

Tctex-1, a novel interaction partner of Rab3D, is required for osteoclastic bone resorption

scientific journal article

The GTPase Rab26 links synaptic vesicles to the autophagy pathway

artículo científico publicado en 2015

The molecular structure and function of sorting nexin 10 in skeletal disorders, cancers, and other pathological conditions

artículo científico publicado en 2020

The oncogene AAMDC links PI3K-AKT-mTOR signaling with metabolic reprograming in estrogen receptor-positive breast cancer

artículo científico publicado en 2021

Thonzonium bromide inhibits RANKL-induced osteoclast formation and bone resorption in vitro and prevents LPS-induced bone loss in vivo.

artículo científico publicado en 2016

Triptolide inhibits osteoclast formation, bone resorption, RANKL-mediated NF-қB activation and titanium particle-induced osteolysis in a mouse model

artículo científico publicado en 2014

V-ATPases in osteoclasts: Structure, function and potential inhibitors of bone resorption

artículo científico publicado el 29 de mayo de 2012