Lista de obras - Charles Harrington - Dominio Público Uruguay

A Protein Aggregation Inhibitor, Leuco-Methylthioninium Bis(Hydromethanesulfonate), Decreases α-Synuclein Inclusions in a Transgenic Mouse Model of Synucleinopathy

artículo científico publicado en 2017

Absence of Abnormal Hyperphosphorylation of Tau in Intracellular Tangles in Alzheimerʼs Disease ⬇️

artículo científico publicado el 1 de septiembre de 1995

Absence of a Role for Phosphorylation in the Tau Pathology of Alzheimer's Disease

artículo científico publicado en 2016

Alpha-Synuclein transgenic mice, h-α-SynL62, display α-Syn aggregation and a dopaminergic phenotype reminiscent of Parkinson's disease

artículo científico publicado en 2017

Alzheimer's Disease-like Paired Helical Filament Assembly from Truncated Tau Protein Is Independent of Disulfide Crosslinking.

artículo científico publicado en 2017

Alzheimer's disease. A glycation connection.

artículo científico publicado en 1994

Assays for the Screening and Characterization of Tau Aggregation Inhibitors.

artículo científico publicado en 2017

Biosynthesis of wall teichoic acids in Staphylococcus aureus H, Micrococcus varians and Bacillus subtilis W23. Involvement of lipid intermediates containing the disaccharide N-acetylmannosaminyl N-acetylglucosamine.

artículo científico publicado en 1985

Calcyclin binding protein and Siah-1 interacting protein in Alzheimer's disease pathology: neuronal localization and possible function

artículo científico publicado en 2012

Characterisation of an Antibody Relevant to the Neuropathology of Alzheimer Disease ⬇️

artículo científico publicado el 1 de enero de 1995

Characterisation of an epitope specific to the neuron-specific isoform of human enolase recognised by a monoclonal antibody raised against a synthetic peptide corresponding to the C-terminus of β/A4-protein ⬇️

artículo científico publicado el 3 de octubre de 1993

Competitive ELISA for the measurement of tau protein in Alzheimer's disease ⬇️

artículo científico publicado el 5 de diciembre de 1990

Complex Disposition of Methylthioninium Redox Forms Determines Efficacy in Tau Aggregation Inhibitor Therapy for Alzheimer's Disease

artículo científico publicado en 2014

Differential compartmental processing and phosphorylation of pathogenic human tau and native mouse tau in the Line 66 model of frontotemporal dementia

artículo científico publicado en 2020

Efficacy and safety of tau-aggregation inhibitor therapy in patients with mild or moderate Alzheimer's disease: a randomised, controlled, double-blind, parallel-arm, phase 3 trial.

artículo científico publicado en 2016

Evaluation of polymorphisms in the presenilin-1 gene and the butyrylcholinesterase gene as risk factors in sporadic Alzheimer's disease

article

Evolution of a homopurine–homopyrimidine pentanucleotide repeat sequence upstream of the human inducible nitric oxide synthase gene ⬇️

artículo científico publicado el 19 de diciembre de 1997

Examination of the validity of the hierarchical model of neuropathological staging in normal aging and Alzheimer's disease.

artículo científico publicado en 1998

Insoluble Vascular Amyloid Deposits Trigger Disruption of the Neurovascular Unit in Alzheimer’s Disease Brains

artículo científico publicado en 2021

Lack of an association of estrogen receptor alpha gene polymorphisms and transcriptional activity with Alzheimer disease

artículo científico publicado en 2000

Lewy body variant of Alzheimer's disease: selective neocortical loss of t-SNARE proteins and loss of MAP2 and alpha-synuclein in medial temporal lobe.

artículo científico publicado en 2009

Measurement of distinct immunochemical presentations of tau protein in Alzheimer disease.

artículo científico publicado en 1991

Methylthioninium chloride reverses cognitive deficits induced by scopolamine: comparison with rivastigmine.

artículo científico publicado en 2008

Modeling Prion-Like Processing of Tau Protein in Alzheimer's Disease for Pharmaceutical Development

artículo científico publicado en 2017

Monoaminergic neuropathology in Alzheimer's disease

artículo científico publicado en 2016

Neuropathological findings in the very old. Results from the first 101 brains of a population-based longitudinal study of dementing disorders

artículo científico publicado en 2000

Potential of Low Dose Leuco-Methylthioninium Bis(Hydromethanesulphonate) (LMTM) Monotherapy for Treatment of Mild Alzheimer's Disease: Cohort Analysis as Modified Primary Outcome in a Phase III Clinical Trial.

artículo científico publicado en 2017

Presence of axonal paired helical filament-tau in Alzheimer's disease: submicroscopic localization.

artículo científico publicado en 1994

Presence of the apolipoprotein E type epsilon 4 allele is not associated with neurofibrillary pathology or biochemical changes to tau protein.

artículo científico publicado en 1997

Presenilin-1 intron 8 polymorphism is not associated with autopsy-confirmed late-onset Alzheimer's disease

scientific article published on 01 January 1997

Selective inhibition of Alzheimer disease-like tau aggregation by phenothiazines

artículo científico publicado en 1996

Staging the pathological assembly of truncated tau protein into paired helical filaments in Alzheimer's disease.

artículo científico publicado en 1996

Stripline resonator and preamplifier for preclinical magnetic resonance imaging at 4.7 T.

artículo científico publicado en 2011

Susceptibility Genetics in the Etiopathogenesis of Alzheimer's Disease: Role for Potential Confounding Factors ⬇️

artículo científico publicado el 1 de septiembre de 1997

Tau Protein Hyperphosphorylation and Aggregation in Alzheimer's Disease and Other Tauopathies, and Possible Neuroprotective Strategies

artículo científico publicado en 2016

Tau aggregation inhibitor therapy: an exploratory phase 2 study in mild or moderate Alzheimer's disease

artículo científico publicado en 2015

Tau-aggregation inhibitor therapy for Alzheimer's disease

artículo científico publicado en 2014

The CCTTT polymorphism in the NOS2A gene is associated with dementia with Lewy bodies.

artículo científico publicado en 2000

The Molecular Pathology of Alzheimer's Disease ⬇️

artículo científico publicado el 1 de febrero de 2012

The relationship between clinical dementia and neuropathological staging (Braak) in a very elderly community sample

artículo científico publicado en 1996

The relationship between truncation and phosphorylation at the C-terminus of tau protein in the paired helical filaments of Alzheimer's disease

artículo científico publicado en 2015

Thiazin red as a neuropathological tool for the rapid diagnosis of Alzheimer's disease in tissue imprints.

artículo científico publicado en 2008

What is the molecular pathology that underlies hippocampal memory decline?

artículo científico publicado en 2009

Lista de obras de Charles Harrington

A Protein Aggregation Inhibitor, Leuco-Methylthioninium Bis(Hydromethanesulfonate), Decreases α-Synuclein Inclusions in a Transgenic Mouse Model of Synucleinopathy

Absence of Abnormal Hyperphosphorylation of Tau in Intracellular Tangles in Alzheimerʼs Disease ⬇️

Absence of a Role for Phosphorylation in the Tau Pathology of Alzheimer's Disease

Alpha-Synuclein transgenic mice, h-α-SynL62, display α-Syn aggregation and a dopaminergic phenotype reminiscent of Parkinson's disease

Alzheimer's Disease-like Paired Helical Filament Assembly from Truncated Tau Protein Is Independent of Disulfide Crosslinking.

Alzheimer's disease. A glycation connection.

Assays for the Screening and Characterization of Tau Aggregation Inhibitors.

Biosynthesis of wall teichoic acids in Staphylococcus aureus H, Micrococcus varians and Bacillus subtilis W23. Involvement of lipid intermediates containing the disaccharide N-acetylmannosaminyl N-acetylglucosamine.

Calcyclin binding protein and Siah-1 interacting protein in Alzheimer's disease pathology: neuronal localization and possible function

Characterisation of an Antibody Relevant to the Neuropathology of Alzheimer Disease ⬇️

Characterisation of an epitope specific to the neuron-specific isoform of human enolase recognised by a monoclonal antibody raised against a synthetic peptide corresponding to the C-terminus of β/A4-protein ⬇️

Competitive ELISA for the measurement of tau protein in Alzheimer's disease ⬇️

Complex Disposition of Methylthioninium Redox Forms Determines Efficacy in Tau Aggregation Inhibitor Therapy for Alzheimer's Disease

Differential compartmental processing and phosphorylation of pathogenic human tau and native mouse tau in the Line 66 model of frontotemporal dementia

Efficacy and safety of tau-aggregation inhibitor therapy in patients with mild or moderate Alzheimer's disease: a randomised, controlled, double-blind, parallel-arm, phase 3 trial.

Evaluation of polymorphisms in the presenilin-1 gene and the butyrylcholinesterase gene as risk factors in sporadic Alzheimer's disease

Evolution of a homopurine–homopyrimidine pentanucleotide repeat sequence upstream of the human inducible nitric oxide synthase gene ⬇️

Examination of the validity of the hierarchical model of neuropathological staging in normal aging and Alzheimer's disease.

Insoluble Vascular Amyloid Deposits Trigger Disruption of the Neurovascular Unit in Alzheimer’s Disease Brains

Lack of an association of estrogen receptor alpha gene polymorphisms and transcriptional activity with Alzheimer disease

Lewy body variant of Alzheimer's disease: selective neocortical loss of t-SNARE proteins and loss of MAP2 and alpha-synuclein in medial temporal lobe.

Measurement of distinct immunochemical presentations of tau protein in Alzheimer disease.

Methylthioninium chloride reverses cognitive deficits induced by scopolamine: comparison with rivastigmine.

Modeling Prion-Like Processing of Tau Protein in Alzheimer's Disease for Pharmaceutical Development

Monoaminergic neuropathology in Alzheimer's disease

Neuropathological findings in the very old. Results from the first 101 brains of a population-based longitudinal study of dementing disorders

Potential of Low Dose Leuco-Methylthioninium Bis(Hydromethanesulphonate) (LMTM) Monotherapy for Treatment of Mild Alzheimer's Disease: Cohort Analysis as Modified Primary Outcome in a Phase III Clinical Trial.

Presence of axonal paired helical filament-tau in Alzheimer's disease: submicroscopic localization.

Presence of the apolipoprotein E type epsilon 4 allele is not associated with neurofibrillary pathology or biochemical changes to tau protein.

Presenilin-1 intron 8 polymorphism is not associated with autopsy-confirmed late-onset Alzheimer's disease

Selective inhibition of Alzheimer disease-like tau aggregation by phenothiazines

Staging the pathological assembly of truncated tau protein into paired helical filaments in Alzheimer's disease.

Stripline resonator and preamplifier for preclinical magnetic resonance imaging at 4.7 T.

Susceptibility Genetics in the Etiopathogenesis of Alzheimer's Disease: Role for Potential Confounding Factors ⬇️

Tau Protein Hyperphosphorylation and Aggregation in Alzheimer's Disease and Other Tauopathies, and Possible Neuroprotective Strategies

Tau aggregation inhibitor therapy: an exploratory phase 2 study in mild or moderate Alzheimer's disease

Tau-aggregation inhibitor therapy for Alzheimer's disease

The CCTTT polymorphism in the NOS2A gene is associated with dementia with Lewy bodies.

The Molecular Pathology of Alzheimer's Disease ⬇️

The relationship between clinical dementia and neuropathological staging (Braak) in a very elderly community sample

The relationship between truncation and phosphorylation at the C-terminus of tau protein in the paired helical filaments of Alzheimer's disease

Thiazin red as a neuropathological tool for the rapid diagnosis of Alzheimer's disease in tissue imprints.

What is the molecular pathology that underlies hippocampal memory decline?