Lista de obras - Younbok Lee - Dominio Público Uruguay

A feedback loop between dipeptide-repeat protein, TDP-43 and karyopherin-α mediates C9orf72-related neurodegeneration

artículo científico publicado en 2018

A novel member of the SAF (scaffold attachment factor)-box protein family inhibits gene expression and induces apoptosis.

artículo científico publicado en 2007

A serum microRNA signature for amyotrophic lateral sclersosis reveals convergent RNA processing defects and identifies presymptomatic mutation carriers.

artículo científico publicado en 2014

Allele-specific knockdown of ALS-associated mutant TDP-43 in neural stem cells derived from induced pluripotent stem cells

artículo científico publicado en 2014

C9orf72 poly GA RAN-translated protein plays a key role in amyotrophic lateral sclerosis via aggregation and toxicity

artículo científico publicado en 2017

Differential roles of the ubiquitin proteasome system and autophagy in the clearance of soluble and aggregated TDP-43 species

artículo científico publicado en 2014

Dipeptide repeat protein inclusions are rare in the spinal cord and almost absent from motor neurons in C9ORF72 mutant amyotrophic lateral sclerosis and are unlikely to cause their degeneration.

artículo científico publicado en 2015

Hexanucleotide repeats in ALS/FTD form length-dependent RNA foci, sequester RNA binding proteins, and are neurotoxic

artículo científico publicado en 2013

Increased utility in the CNS of a powerful neuron-specific tetracycline-regulatable adenoviral system developed using a post-transcriptional enhancer.

artículo científico publicado en 2005

MicroRNA-132 regulates recognition memory and synaptic plasticity in the perirhinal cortex.

artículo científico publicado en 2012

Muscarinic receptors induce LTD of NMDAR EPSCs via a mechanism involving hippocalcin, AP2 and PSD-95.

artículo científico publicado en 2010

Nuclear RNA foci from C9ORF72 expansion mutation form paraspeckle-like bodies

artículo científico publicado en 2019

Optimizing regulatable gene expression using adenoviral vectors.

artículo científico publicado en 2004

Phosphorylation of C-terminal tyrosine residue 526 in FUS impairs its nuclear import.

artículo científico publicado en 2015

RNA Misprocessing in C9orf72-Linked Neurodegeneration

artículo científico publicado en 2017

SAFB re-distribution marks steps of the apoptotic process.

artículo científico publicado en 2007

The C9ORF72 expansion mutation is a common cause of ALS+/-FTD in Europe and has a single founder

artículo científico publicado en 2012

Twist-1 regulates the miR-199a/214 cluster during development

artículo científico publicado en 2009

Lista de obras de Younbok Lee

A feedback loop between dipeptide-repeat protein, TDP-43 and karyopherin-α mediates C9orf72-related neurodegeneration

A novel member of the SAF (scaffold attachment factor)-box protein family inhibits gene expression and induces apoptosis.

A serum microRNA signature for amyotrophic lateral sclersosis reveals convergent RNA processing defects and identifies presymptomatic mutation carriers.

Allele-specific knockdown of ALS-associated mutant TDP-43 in neural stem cells derived from induced pluripotent stem cells

C9orf72 poly GA RAN-translated protein plays a key role in amyotrophic lateral sclerosis via aggregation and toxicity

Differential roles of the ubiquitin proteasome system and autophagy in the clearance of soluble and aggregated TDP-43 species

Dipeptide repeat protein inclusions are rare in the spinal cord and almost absent from motor neurons in C9ORF72 mutant amyotrophic lateral sclerosis and are unlikely to cause their degeneration.

Hexanucleotide repeats in ALS/FTD form length-dependent RNA foci, sequester RNA binding proteins, and are neurotoxic

Increased utility in the CNS of a powerful neuron-specific tetracycline-regulatable adenoviral system developed using a post-transcriptional enhancer.

MicroRNA-132 regulates recognition memory and synaptic plasticity in the perirhinal cortex.

Muscarinic receptors induce LTD of NMDAR EPSCs via a mechanism involving hippocalcin, AP2 and PSD-95.

Nuclear RNA foci from C9ORF72 expansion mutation form paraspeckle-like bodies

Optimizing regulatable gene expression using adenoviral vectors.

Phosphorylation of C-terminal tyrosine residue 526 in FUS impairs its nuclear import.

RNA Misprocessing in C9orf72-Linked Neurodegeneration

SAFB re-distribution marks steps of the apoptotic process.

The C9ORF72 expansion mutation is a common cause of ALS+/-FTD in Europe and has a single founder

Twist-1 regulates the miR-199a/214 cluster during development