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Lista de obras de Albert Gough

A glass-based, continuously zonated and vascularized human liver acinus microphysiological system (vLAMPS) designed for experimental modeling of diseases and ADME/TOX.

artículo científico publicado en 2018

A human liver microphysiology platform for investigating physiology, drug safety, and disease models

artículo científico publicado en 2015

A metric and workflow for quality control in the analysis of heterogeneity in phenotypic profiles and screens

artículo científico publicado en 2015

Applications of the microphysiology systems database for experimental ADME-Tox and disease models

scientific article published on 25 March 2020

Automated light microscopy for the study of the brain: cellular and molecular dynamics, development, and tumorigenesis.

artículo científico publicado en 1997

Biologically Relevant Heterogeneity: Metrics and Practical Insights

artículo científico publicado en 2017

Characterization and quantitation of NF-kappaB nuclear translocation induced by interleukin-1 and tumor necrosis factor-alpha. Development and use of a high capacity fluorescence cytometric system.

artículo científico publicado en 1998

Control of oxygen tension recapitulates zone-specific functions in human liver microphysiology systems

artículo científico publicado en 2017

Fluorescent protein biosensors applied to microphysiological systems

artículo científico publicado en 2015

Identifying and quantifying heterogeneity in high content analysis: application of heterogeneity indices to drug discovery

artículo científico publicado en 2014

Integrating Analysis of Cellular Heterogeneity in High-Content Dose-Response Studies

artículo científico publicado en 2018

In vitro platforms for evaluating liver toxicity

artículo científico publicado en 2014

Modeling the Effect of the Metastatic Microenvironment on Phenotypes Conferred by Estrogen Receptor Mutations Using a Human Liver Microphysiological System.

artículo científico publicado en 2019

Platform for Quantitative Evaluation of Spatial Intratumoral Heterogeneity in Multiplexed Fluorescence Images.

artículo científico publicado en 2017

Pre-clinical and clinical investigations of metabolic zonation in liver diseases: The potential of microphysiology systems.

artículo científico publicado en 2017

Spatial domain analysis predicts risk of colorectal cancer recurrence and infers associated tumor microenvironment networks

artículo científico publicado en 2020

The Combination of a Human Biomimetic Liver Microphysiology System with BIOLOGXsym, a Quantitative Systems Toxicology (QST) Modeling Platform for Macromolecules, Provides Mechanistic Understanding of Tocilizumab- and GGF2-Induced Liver Injury

artículo científico publicado en 2023

Towards a three-dimensional microfluidic liver platform for predicting drug efficacy and toxicity in humans

artículo científico publicado en 2013

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