Lista de obras - Lawrence Vernetti - Dominio Público Uruguay

'Seed' analysis of off-target siRNAs reveals an essential role of Mcl-1 in resistance to the small-molecule Bcl-2/Bcl-XL inhibitor ABT-737.

artículo científico publicado en 2006

A Tumor Cell-Selective Inhibitor of Mitogen-Activated Protein Kinase Phosphatases Sensitizes Breast Cancer Cells to Lymphokine-Activated Killer Cell Activity.

artículo científico publicado en 2017

A human liver microphysiology platform for investigating physiology, drug safety, and disease models

artículo científico publicado en 2015

ATP depletion is associated with cytotoxicity of a novel lipid regulator in guinea pig adrenocortical cells

artículo científico publicado en 1993

Adaptation of an in vitro phospholipidosis assay to an automated image analysis system

scientific article published on 01 January 2007

Control of oxygen tension recapitulates zone-specific functions in human liver microphysiology systems

artículo científico publicado en 2017

Delayed treatment with PTBA analogs reduces postinjury renal fibrosis after kidney injury

artículo científico publicado en 2015

Design and evaluation of novel glutaminase inhibitors

artículo científico publicado en 2016

Evaluation of positive controls for the in vitro unscheduled DNA synthesis assay using hepatocytes from induced (Aroclor 1254) and uninduced male cynomolgus monkey.

artículo científico publicado en 1997

Evolution of Experimental Models of the Liver to Predict Human Drug Hepatotoxicity and Efficacy.

artículo científico publicado en 2017

Fluorescent protein biosensors applied to microphysiological systems

artículo científico publicado en 2015

Functional Coupling of Human Microphysiology Systems: Intestine, Liver, Kidney Proximal Tubule, Blood-Brain Barrier and Skeletal Muscle.

artículo científico publicado en 2017

Identifying and quantifying heterogeneity in high content analysis: application of heterogeneity indices to drug discovery

artículo científico publicado en 2014

In vitro platforms for evaluating liver toxicity

artículo científico publicado en 2014

Pre-clinical and clinical investigations of metabolic zonation in liver diseases: The potential of microphysiology systems.

artículo científico publicado en 2017

Selective Alteration of Cytokeratin Intermediate Filament by Cyclosporine A is a Lethal Toxicity in PTK2 Cell Cultures ⬇️

artículo científico publicado el 1 de enero de 1991

Survivin depletion preferentially reduces the survival of activated K-Ras-transformed cells.

artículo científico publicado en 2007

The Combination of a Human Biomimetic Liver Microphysiology System with BIOLOGXsym, a Quantitative Systems Toxicology (QST) Modeling Platform for Macromolecules, Provides Mechanistic Understanding of Tocilizumab- and GGF2-Induced Liver Injury

artículo científico publicado en 2023

The Microphysiology Systems Database for Analyzing and Modeling Compound Interactions with Human and Animal Organ Models

artículo científico publicado en 2016

Towards a three-dimensional microfluidic liver platform for predicting drug efficacy and toxicity in humans

artículo científico publicado en 2013

Lista de obras de Lawrence Vernetti

'Seed' analysis of off-target siRNAs reveals an essential role of Mcl-1 in resistance to the small-molecule Bcl-2/Bcl-XL inhibitor ABT-737.

A Tumor Cell-Selective Inhibitor of Mitogen-Activated Protein Kinase Phosphatases Sensitizes Breast Cancer Cells to Lymphokine-Activated Killer Cell Activity.

A human liver microphysiology platform for investigating physiology, drug safety, and disease models

ATP depletion is associated with cytotoxicity of a novel lipid regulator in guinea pig adrenocortical cells

Adaptation of an in vitro phospholipidosis assay to an automated image analysis system

Control of oxygen tension recapitulates zone-specific functions in human liver microphysiology systems

Delayed treatment with PTBA analogs reduces postinjury renal fibrosis after kidney injury

Design and evaluation of novel glutaminase inhibitors

Evaluation of positive controls for the in vitro unscheduled DNA synthesis assay using hepatocytes from induced (Aroclor 1254) and uninduced male cynomolgus monkey.

Evolution of Experimental Models of the Liver to Predict Human Drug Hepatotoxicity and Efficacy.

Fluorescent protein biosensors applied to microphysiological systems

Functional Coupling of Human Microphysiology Systems: Intestine, Liver, Kidney Proximal Tubule, Blood-Brain Barrier and Skeletal Muscle.

Identifying and quantifying heterogeneity in high content analysis: application of heterogeneity indices to drug discovery

In vitro platforms for evaluating liver toxicity

Pre-clinical and clinical investigations of metabolic zonation in liver diseases: The potential of microphysiology systems.

Selective Alteration of Cytokeratin Intermediate Filament by Cyclosporine A is a Lethal Toxicity in PTK2 Cell Cultures ⬇️

Survivin depletion preferentially reduces the survival of activated K-Ras-transformed cells.

The Combination of a Human Biomimetic Liver Microphysiology System with BIOLOGXsym, a Quantitative Systems Toxicology (QST) Modeling Platform for Macromolecules, Provides Mechanistic Understanding of Tocilizumab- and GGF2-Induced Liver Injury

The Microphysiology Systems Database for Analyzing and Modeling Compound Interactions with Human and Animal Organ Models

Towards a three-dimensional microfluidic liver platform for predicting drug efficacy and toxicity in humans