Lista de obras - Rosa Molfetta - Dominio Público Uruguay

3D Microfluidic model for evaluating immunotherapy efficacy by tracking dendritic cell behaviour toward tumor cells

artículo científico publicado en 2017

Abnormal regulation of BCR signalling by c-Cbl in chronic lymphocytic leukaemia

artículo científico publicado en 2018

Activation of Syk tyrosine kinase is required for c-Cbl-mediated ubiquitination of Fcepsilon RI and Syk in RBL cells.

artículo científico publicado en 2002

Activation of liver X receptor up-regulates the expression of the NKG2D ligands MICA and MICB in multiple myeloma through different molecular mechanisms

artículo científico publicado en 2019

Bone Marrow Stromal Cell-Derived IL-8 Upregulates PVR Expression on Multiple Myeloma Cells via NF-kB Transcription Factor

scientific article published on 13 February 2020

CD155: A Multi-Functional Molecule in Tumor Progression

scientific article published on 30 January 2020

CIN85 regulates the ligand-dependent endocytosis of the IgE receptor: a new molecular mechanism to dampen mast cell function

artículo científico publicado en 2005

Cbl family proteins: balancing FcεRI-mediated mast cell and basophil activation

artículo científico publicado en 2011

FcεRI Signaling in the Modulation of Allergic Response: Role of Mast Cell-Derived Exosomes

artículo científico publicado en 2020

Genotoxic Stress Induces Senescence-Associated ADAM10-Dependent Release of NKG2D MIC Ligands in Multiple Myeloma Cells.

artículo científico publicado en 2015

Genotoxic stress modulates the release of exosomes from multiple myeloma cells capable of activating NK cell cytokine production: Role of HSP70/TLR2/NF-kB axis.

artículo científico publicado en 2017

Immune complexes exposed on mast cell-derived nanovesicles amplify allergic inflammation

artículo científico publicado en 2019

Inhibition of bromodomain and extra-terminal (BET) proteins increases NKG2D ligand MICA expression and sensitivity to NK cell-mediated cytotoxicity in multiple myeloma cells: role of cMYC-IRF4-miR-125b interplay

artículo científico publicado en 2016

Innate immune activating ligand SUMOylation affects tumor cell recognition by NK cells.

artículo científico publicado en 2017

Lipid raft-dependent FcepsilonRI ubiquitination regulates receptor endocytosis through the action of ubiquitin binding adaptors

artículo científico publicado en 2009

NGF-dependent and tissue-specific transcription of vgf is regulated by a CREB-p300 and bHLH factor interaction

artículo científico publicado en 2002

NK cells and interferons.

artículo científico publicado en 2014

NKG2D and Its Ligands: "One for All, All for One".

artículo científico publicado en 2018

Negative signals from FcepsilonRI engagement attenuate mast cell functions.

artículo científico publicado en 2007

Nitric oxide donors increase PVR/CD155 DNAM-1 ligand expression in multiple myeloma cells: role of DNA damage response activation.

artículo científico publicado en 2015

Obinutuzumab-mediated high-affinity ligation of FcγRIIIA/CD16 primes NK cells for IFNγ production

artículo científico publicado en 2017

PIP2-dependent regulation of Munc13-4 endocytic recycling: impact on the cytolytic secretory pathway

artículo científico publicado en 2012

Post-translational Mechanisms Regulating NK Cell Activating Receptors and Their Ligands in Cancer: Potential Targets for Therapeutic Intervention

artículo científico publicado en 2019

Regulation of NKG2D Expression and Signaling by Endocytosis

artículo científico publicado en 2016

Regulation of NKG2D-Dependent NK Cell Functions: The Yin and the Yang of Receptor Endocytosis

artículo científico publicado en 2017

Regulation of fc receptor endocytic trafficking by ubiquitination.

artículo científico

SAMHD1 phosphorylation and cytoplasmic relocalization after human cytomegalovirus infection limits its antiviral activity

scientific article published on 28 September 2020

Syk-dependent regulation of Hrs phosphorylation and ubiquitination upon FcεRI engagement: impact on Hrs membrane/cytosol localization

scientific journal article

The IMiDs targets IKZF-1/3 and IRF4 as novel negative regulators of NK cell-activating ligands expression in multiple myeloma

artículo científico publicado en 2015

The Ubiquitin-proteasome pathway regulates Nectin2/CD112 expression and impairs NK cell recognition and killing

scientific article published on 27 March 2019

The adaptor molecule CIN85 regulates Syk tyrosine kinase level by activating the ubiquitin-proteasome degradation pathway

scientific journal article

The homeobox transcription factor MEIS2 is a regulator of cancer cell survival and IMiDs activity in Multiple Myeloma: modulation by Bromodomain and Extra-Terminal (BET) protein inhibitors

artículo científico publicado en 2019

Translating the anti-myeloma activity of Natural Killer cells into clinical application

artículo científico publicado en 2018

Ubiquitin-dependent endocytosis of NKG2D-DAP10 receptor complexes activates signaling and functions in human NK cells.

artículo científico publicado en 2015

Ubiquitination and degradation of Syk and ZAP-70 protein tyrosine kinases in human NK cells upon CD16 engagement.

artículo científico publicado en 2001

c-Cbl regulates MICA- but not ULBP2-induced NKG2D down-modulation in human NK cells.

artículo científico publicado en 2014

p38 MAPK differentially controls NK activating ligands at transcriptional and post-transcriptional level on multiple myeloma cells.

artículo científico publicado en 2016

Lista de obras de Rosa Molfetta

3D Microfluidic model for evaluating immunotherapy efficacy by tracking dendritic cell behaviour toward tumor cells

Abnormal regulation of BCR signalling by c-Cbl in chronic lymphocytic leukaemia

Activation of Syk tyrosine kinase is required for c-Cbl-mediated ubiquitination of Fcepsilon RI and Syk in RBL cells.

Activation of liver X receptor up-regulates the expression of the NKG2D ligands MICA and MICB in multiple myeloma through different molecular mechanisms

Bone Marrow Stromal Cell-Derived IL-8 Upregulates PVR Expression on Multiple Myeloma Cells via NF-kB Transcription Factor

CD155: A Multi-Functional Molecule in Tumor Progression

CIN85 regulates the ligand-dependent endocytosis of the IgE receptor: a new molecular mechanism to dampen mast cell function

Cbl family proteins: balancing FcεRI-mediated mast cell and basophil activation

FcεRI Signaling in the Modulation of Allergic Response: Role of Mast Cell-Derived Exosomes

Genotoxic Stress Induces Senescence-Associated ADAM10-Dependent Release of NKG2D MIC Ligands in Multiple Myeloma Cells.

Genotoxic stress modulates the release of exosomes from multiple myeloma cells capable of activating NK cell cytokine production: Role of HSP70/TLR2/NF-kB axis.

Immune complexes exposed on mast cell-derived nanovesicles amplify allergic inflammation

Inhibition of bromodomain and extra-terminal (BET) proteins increases NKG2D ligand MICA expression and sensitivity to NK cell-mediated cytotoxicity in multiple myeloma cells: role of cMYC-IRF4-miR-125b interplay

Innate immune activating ligand SUMOylation affects tumor cell recognition by NK cells.

Lipid raft-dependent FcepsilonRI ubiquitination regulates receptor endocytosis through the action of ubiquitin binding adaptors

NGF-dependent and tissue-specific transcription of vgf is regulated by a CREB-p300 and bHLH factor interaction

NK cells and interferons.

NKG2D and Its Ligands: "One for All, All for One".

Negative signals from FcepsilonRI engagement attenuate mast cell functions.

Nitric oxide donors increase PVR/CD155 DNAM-1 ligand expression in multiple myeloma cells: role of DNA damage response activation.

Obinutuzumab-mediated high-affinity ligation of FcγRIIIA/CD16 primes NK cells for IFNγ production

PIP2-dependent regulation of Munc13-4 endocytic recycling: impact on the cytolytic secretory pathway

Post-translational Mechanisms Regulating NK Cell Activating Receptors and Their Ligands in Cancer: Potential Targets for Therapeutic Intervention

Regulation of NKG2D Expression and Signaling by Endocytosis

Regulation of NKG2D-Dependent NK Cell Functions: The Yin and the Yang of Receptor Endocytosis

Regulation of fc receptor endocytic trafficking by ubiquitination.

SAMHD1 phosphorylation and cytoplasmic relocalization after human cytomegalovirus infection limits its antiviral activity

Syk-dependent regulation of Hrs phosphorylation and ubiquitination upon FcεRI engagement: impact on Hrs membrane/cytosol localization

The IMiDs targets IKZF-1/3 and IRF4 as novel negative regulators of NK cell-activating ligands expression in multiple myeloma

The Ubiquitin-proteasome pathway regulates Nectin2/CD112 expression and impairs NK cell recognition and killing

The adaptor molecule CIN85 regulates Syk tyrosine kinase level by activating the ubiquitin-proteasome degradation pathway

The homeobox transcription factor MEIS2 is a regulator of cancer cell survival and IMiDs activity in Multiple Myeloma: modulation by Bromodomain and Extra-Terminal (BET) protein inhibitors

Translating the anti-myeloma activity of Natural Killer cells into clinical application

Ubiquitin-dependent endocytosis of NKG2D-DAP10 receptor complexes activates signaling and functions in human NK cells.

Ubiquitination and degradation of Syk and ZAP-70 protein tyrosine kinases in human NK cells upon CD16 engagement.

c-Cbl regulates MICA- but not ULBP2-induced NKG2D down-modulation in human NK cells.

p38 MAPK differentially controls NK activating ligands at transcriptional and post-transcriptional level on multiple myeloma cells.