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Lista de obras de Lukas Hroch

1-(Benzo[d]thiazol-2-yl)-3-phenylureas as dual inhibitors of casein kinase 1 and ABAD enzymes for treatment of neurodegenerative disorders.

artículo científico publicado en 2018

6-benzothiazolyl ureas, thioureas and guanidines are potent inhibitors of ABAD/17β-HSD10 and potential drugs for Alzheimer's disease treatment: Design, synthesis and in vitro evaluation.

artículo científico publicado en 2017

A Direct interaction between mitochondrial proteins and amyloid-β peptide and its significance for the progression and treatment of Alzheimer`s disease.

artículo científico publicado en 2015

Benzothiazoles - scaffold of interest for CNS targeted drugs.

artículo científico publicado en 2015

Benzothiazolyl Ureas are Low Micromolar and Uncompetitive Inhibitors of 17β-HSD10 with Implications to Alzheimer's Disease Treatment

scientific article published on 17 March 2020

Design, Synthesis and in vitro Evaluation of Indolotacrine Analogues as Multitarget-Directed Ligands for the Treatment of Alzheimer's Disease.

artículo científico publicado en 2015

Design, synthesis and in vitro evaluation of benzothiazole-based ureas as potential ABAD/17β-HSD10 modulators for Alzheimer's disease treatment

artículo científico publicado en 2016

Novel Benzothiazole-based Ureas as 17β-HSD10 Inhibitors, A Potential Alzheimer's Disease Treatment

artículo científico publicado en 2019

Rational design of novel TLR4 ligands by in silico screening and their functional and structural characterization in vitro.

artículo científico publicado en 2018

Reduction of Folate by Dihydrofolate Reductase from Thermotoga maritima

artículo científico publicado en 2017

Synthesis and evaluation of frentizole-based indolyl thiourea analogues as MAO/ABAD inhibitors for Alzheimer's disease treatment

artículo científico publicado en 2016

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