Lista de obras - Jens U Marquardt - Dominio Público Uruguay

Adverse genomic alterations and stemness features are induced by field cancerization in the microenvironment of hepatocellular carcinomas

artículo científico publicado en 2017

An integrated genomic and epigenomic approach predicts therapeutic response to zebularine in human liver cancer

artículo científico publicado en 2010

Antitumor effects in hepatocarcinoma of isoform-selective inhibition of HDAC2.

artículo científico publicado en 2014

Application of patient-derived liver cancer cells for phenotypic characterization and therapeutic target identification

scientific article published on 14 December 2018

CD44 (Cluster of differentiation 44) promotes osteosarcoma progression in mice lacking the tumor suppressor Merlin

artículo científico publicado en 2020

Cholesterol burden in the liver induces mitochondrial dynamic changes and resistance to apoptosis

scientific article published on 21 September 2018

Cholesterol overload in the liver aggravates oxidative stress-mediated DNA damage and accelerates hepatocarcinogenesis

artículo científico publicado en 2017

Common variants in the HLA-DQ region confer susceptibility to idiopathic achalasia.

artículo científico publicado en 2014

Context-Dependent Role of NF-κB Signaling in Primary Liver Cancer-from Tumor Development to Therapeutic Implications

artículo científico publicado en 2019

Contribution of hepatic lineage stage-specific donor memory to the differential potential of induced mouse pluripotent stem cells

artículo científico publicado en 2012

Curcumin effectively inhibits oncogenic NF-κB signaling and restrains stemness features in liver cancer

artículo científico publicado en 2015

Cytoplasmic localization of the cell polarity factor Scribble supports liver tumor formation and tumor cell invasiveness.

artículo científico publicado en 2017

DNMT1 is a required genomic regulator for murine liver histogenesis and regeneration.

artículo científico publicado en 2016

Deconvolution of the cellular origin in hepatocellular carcinoma: Hepatocytes take the center stage

artículo científico publicado en 2016

Definition of ubiquitination modulator COP1 as a novel therapeutic target in human hepatocellular carcinoma

artículo científico publicado en 2010

Epigenetic reprogramming modulates malignant properties of human liver cancer.

artículo científico publicado en 2014

Functional and genetic deconstruction of the cellular origin in liver cancer.

artículo científico publicado en 2015

Ginkgo biloba induces different gene expression signatures and oncogenic pathways in malignant and non-malignant cells of the liver

artículo científico publicado en 2018

Hepatocyte growth factor/c-met signaling is required for stem-cell-mediated liver regeneration in mice.

artículo científico publicado en 2012

High-definition endoscopy with iScan and Lugol's solution for the detection of inflammation in patients with nonerosive reflux disease: histologic evaluation in comparison with a control group.

artículo científico publicado en 2014

Human hepatic cancer stem cells are characterized by common stemness traits and diverse oncogenic pathways.

artículo científico publicado en 2011

IgG4-related sclerosing cholangitis mimicking cholangiocarcinoma.

artículo científico

Immunotherapy of Hepatocellular Carcinoma

artículo científico publicado en 2018

Impact of Individual Components of the Metabolic Syndrome on the Outcome of Patients with Advanced Hepatocellular Carcinoma Treated with Sorafenib

artículo científico publicado en 2017

Improved Prediction of Survival by a Risk Factor-Integrating Inflammatory Score in Sorafenib-Treated Hepatocellular Carcinoma

scientific article published on 04 October 2018

Inclusion of targeted therapies in the standard of care for metastatic colorectal cancer patients in a German cancer center: the more the better?!

artículo científico publicado en 2014

Increased liver carcinogenesis and enrichment of stem cell properties in livers of Dickkopf 2 (Dkk2) deleted mice

artículo científico publicado en 2015

Induction of Chromosome Instability by Activation of Yes-Associated Protein and Forkhead Box M1 in Liver Cancer.

artículo científico publicado en 2017

Linking MLL and the HGF-MET signaling pathway in liver cancer

artículo científico publicado en 2013

Loss of c-Met accelerates development of liver fibrosis in response to CCl4 exposure through deregulation of multiple molecular pathways ⬇️

artículo científico publicado el 22 de febrero de 2012

Loss of c-Met disrupts gene expression program required for G2/M progression during liver regeneration in mice

artículo científico publicado en 2010

Loss of c-Met signaling sensitizes hepatocytes to lipotoxicity and induces cholestatic liver damage by aggravating oxidative stress.

scientific article published on 06 July 2016

Loss of organic cation transporter 3 (Oct3) leads to enhanced proliferation and hepatocarcinogenesis.

artículo científico publicado en 2017

MYC activates stem-like cell potential in hepatocarcinoma by a p53-dependent mechanism.

artículo científico publicado en 2014

MicroRNA-27a-3p targets FoxO signalling to induce tumour-like phenotypes in bile duct cells

artículo científico publicado en 2022

Mitochondrial BAX Determines the Predisposition to Apoptosis in Human AML.

artículo científico publicado en 2017

Modeling pathogenesis of primary liver cancer in lineage-specific mouse cell types.

artículo científico publicado en 2013

Molecular diagnosis and therapy of hepatocellular carcinoma (HCC): an emerging field for advanced technologies.

scientific article published on 23 July 2011

Murine Liver Organoids as a Genetically Flexible System to Study Liver Cancer and

artículo científico publicado en 2019

NOTCH target gene HES5 mediates oncogenic and tumor suppressive functions in hepatocarcinogenesis

artículo científico publicado en 2020

Neighbor of Punc E11, a novel oncofetal marker for hepatocellular carcinoma.

artículo científico publicado en 2011

Next-generation genomic profiling of hepatocellular adenomas: a new era of individualized patient care.

artículo científico publicado en 2014

Next-generation sequencing: application in liver cancer-past, present and future?

artículo científico

Obere gastrointestinale Blutung mit hämorrhagischem Schock am Ende einer Urlaubsreise: Präklinische und innerklinische Versorgung eines gastrointestinalen Notfalls

artículo científico publicado en 2014

Oncogenic driver genes and the inflammatory microenvironment dictate liver tumor phenotype

artículo científico publicado en 2016

Prospective evaluation of the impact of covert hepatic encephalopathy on quality of life and sleep in cirrhotic patients

artículo científico publicado en 2018

Pulmonary resection for metastatic gastric cancer

scientific article published on 01 November 2010

RNA-Seq Atlas--a reference database for gene expression profiling in normal tissue by next-generation sequencing.

artículo científico publicado en 2012

Recipient liver function before liver transplantation influences post-transplantation survival in patients with HCC

scientific article published on 30 May 2018

Recombinant human hepatocyte growth factor provides protective effects in celurein-induced acute pancreatitis in mice.

artículo científico publicado en 2018

Regulation of microRNAs and their role in liver development, regeneration and disease.

artículo científico publicado en 2014

Sall4 in “Stemness”-Driven Hepatocarcinogenesis ⬇️

artículo científico publicado el 13 de junio de 2013

Sequential transcriptome analysis of human liver cancer indicates late stage acquisition of malignant traits.

artículo científico publicado en 2013

Sirtuin-6–Dependent Genetic And Epigenetic Alterations Are Associated With Poor Clinical Outcome in Hepatocellular Carcinoma Patients ⬇️

artículo científico publicado el 30 de julio de 2013

SnapShot: Hepatocellular carcinoma

artículo científico publicado en 2014

Snapshot liver transcriptome in hepatocellular carcinoma

scientific article published on 13 December 2011

Stem cells in hepatocarcinogenesis: evidence from genomic data

artículo científico publicado en 2010

Surveillance of Hepatocellular Carcinoma and Diagnostic Algorithms in Patients with Liver Cirrhosis

artículo científico publicado en 2016

The Role of Transforming Growth Factor-β in Human Hepatocarcinogenesis: Mechanistic and Therapeutic Implications From an Integrative Multiomics Approach.

artículo científico publicado en 2017

The functional cancer map: a systems-level synopsis of genetic deregulation in cancer

artículo científico publicado en 2011

The immune contexture of hepatocellular carcinoma predicts clinical outcome

artículo científico publicado en 2018

The impact of patient and tumour baseline characteristics on the overall survival of patients with advanced hepatocellular carcinoma treated with sorafenib.

artículo científico publicado en 2012

The role of molecular enrichment on future therapies in hepatocellular carcinoma

artículo científico publicado en 2018

Transarterial chemoembolization versus sorafenib in patients with hepatocellular carcinoma and extrahepatic disease

artículo científico publicado en 2017

Translating bioinformatics in oncology: guilt-by-profiling analysis and identification of KIF18B and CDCA3 as novel driver genes in carcinogenesis

artículo científico publicado en 2014

Treatment and survival of non-alcoholic steatohepatitis associated hepatocellular carcinoma

artículo científico publicado en 2015

Use of inhibitors of the renin-angiotensin system is associated with longer survival in patients with hepatocellular carcinoma

artículo científico publicado en 2017

Validation of the simplified Animal Naming Test as primary screening tool for the diagnosis of covert hepatic encephalopathy

scientific article published on 19 August 2018

YAP-dependent induction of UHMK1 supports nuclear enrichment of the oncogene MYBL2 and proliferation in liver cancer cells

scientific article published on 01 April 2019

[Etiology and complications of liver cirrhosis: data from a German centre].

artículo científico publicado en 2014

[Hepatocellular carcinoma: molecular pathogenesis and novel targets for therapy]

artículo científico publicado en 2012

[Hepatocellular carcinoma: what's new?]

artículo científico publicado en 2012

[Hepatocellular carcinoma]

scientific article published on 01 May 2017

[Personalised hepatology - current concepts, developments and expectations in the post-genome era]

artículo científico publicado en 2012

[Response to Terlipressin and albumin is associated with improved outcome in patients with cirrhosis and hepatorenal syndrome]

artículo científico publicado en 2015

Lista de obras de Jens U Marquardt

Adverse genomic alterations and stemness features are induced by field cancerization in the microenvironment of hepatocellular carcinomas

An integrated genomic and epigenomic approach predicts therapeutic response to zebularine in human liver cancer

Antitumor effects in hepatocarcinoma of isoform-selective inhibition of HDAC2.

Application of patient-derived liver cancer cells for phenotypic characterization and therapeutic target identification

CD44 (Cluster of differentiation 44) promotes osteosarcoma progression in mice lacking the tumor suppressor Merlin

Cholesterol burden in the liver induces mitochondrial dynamic changes and resistance to apoptosis

Cholesterol overload in the liver aggravates oxidative stress-mediated DNA damage and accelerates hepatocarcinogenesis

Common variants in the HLA-DQ region confer susceptibility to idiopathic achalasia.

Context-Dependent Role of NF-κB Signaling in Primary Liver Cancer-from Tumor Development to Therapeutic Implications

Contribution of hepatic lineage stage-specific donor memory to the differential potential of induced mouse pluripotent stem cells

Curcumin effectively inhibits oncogenic NF-κB signaling and restrains stemness features in liver cancer

Cytoplasmic localization of the cell polarity factor Scribble supports liver tumor formation and tumor cell invasiveness.

DNMT1 is a required genomic regulator for murine liver histogenesis and regeneration.

Deconvolution of the cellular origin in hepatocellular carcinoma: Hepatocytes take the center stage

Definition of ubiquitination modulator COP1 as a novel therapeutic target in human hepatocellular carcinoma

Epigenetic reprogramming modulates malignant properties of human liver cancer.

Functional and genetic deconstruction of the cellular origin in liver cancer.

Ginkgo biloba induces different gene expression signatures and oncogenic pathways in malignant and non-malignant cells of the liver

Hepatocyte growth factor/c-met signaling is required for stem-cell-mediated liver regeneration in mice.

High-definition endoscopy with iScan and Lugol's solution for the detection of inflammation in patients with nonerosive reflux disease: histologic evaluation in comparison with a control group.

Human hepatic cancer stem cells are characterized by common stemness traits and diverse oncogenic pathways.

IgG4-related sclerosing cholangitis mimicking cholangiocarcinoma.

Immunotherapy of Hepatocellular Carcinoma

Impact of Individual Components of the Metabolic Syndrome on the Outcome of Patients with Advanced Hepatocellular Carcinoma Treated with Sorafenib

Improved Prediction of Survival by a Risk Factor-Integrating Inflammatory Score in Sorafenib-Treated Hepatocellular Carcinoma

Inclusion of targeted therapies in the standard of care for metastatic colorectal cancer patients in a German cancer center: the more the better?!

Increased liver carcinogenesis and enrichment of stem cell properties in livers of Dickkopf 2 (Dkk2) deleted mice

Induction of Chromosome Instability by Activation of Yes-Associated Protein and Forkhead Box M1 in Liver Cancer.

Linking MLL and the HGF-MET signaling pathway in liver cancer

Loss of c-Met accelerates development of liver fibrosis in response to CCl4 exposure through deregulation of multiple molecular pathways ⬇️

Loss of c-Met disrupts gene expression program required for G2/M progression during liver regeneration in mice

Loss of c-Met signaling sensitizes hepatocytes to lipotoxicity and induces cholestatic liver damage by aggravating oxidative stress.

Loss of organic cation transporter 3 (Oct3) leads to enhanced proliferation and hepatocarcinogenesis.

MYC activates stem-like cell potential in hepatocarcinoma by a p53-dependent mechanism.

MicroRNA-27a-3p targets FoxO signalling to induce tumour-like phenotypes in bile duct cells

Mitochondrial BAX Determines the Predisposition to Apoptosis in Human AML.

Modeling pathogenesis of primary liver cancer in lineage-specific mouse cell types.

Molecular diagnosis and therapy of hepatocellular carcinoma (HCC): an emerging field for advanced technologies.

Murine Liver Organoids as a Genetically Flexible System to Study Liver Cancer and

NOTCH target gene HES5 mediates oncogenic and tumor suppressive functions in hepatocarcinogenesis

Neighbor of Punc E11, a novel oncofetal marker for hepatocellular carcinoma.

Next-generation genomic profiling of hepatocellular adenomas: a new era of individualized patient care.

Next-generation sequencing: application in liver cancer-past, present and future?

Obere gastrointestinale Blutung mit hämorrhagischem Schock am Ende einer Urlaubsreise: Präklinische und innerklinische Versorgung eines gastrointestinalen Notfalls

Oncogenic driver genes and the inflammatory microenvironment dictate liver tumor phenotype

Prospective evaluation of the impact of covert hepatic encephalopathy on quality of life and sleep in cirrhotic patients

Pulmonary resection for metastatic gastric cancer

RNA-Seq Atlas--a reference database for gene expression profiling in normal tissue by next-generation sequencing.

Recipient liver function before liver transplantation influences post-transplantation survival in patients with HCC

Recombinant human hepatocyte growth factor provides protective effects in celurein-induced acute pancreatitis in mice.

Regulation of microRNAs and their role in liver development, regeneration and disease.

Sall4 in “Stemness”-Driven Hepatocarcinogenesis ⬇️

Sequential transcriptome analysis of human liver cancer indicates late stage acquisition of malignant traits.

Sirtuin-6–Dependent Genetic And Epigenetic Alterations Are Associated With Poor Clinical Outcome in Hepatocellular Carcinoma Patients ⬇️

SnapShot: Hepatocellular carcinoma

Snapshot liver transcriptome in hepatocellular carcinoma

Stem cells in hepatocarcinogenesis: evidence from genomic data

Surveillance of Hepatocellular Carcinoma and Diagnostic Algorithms in Patients with Liver Cirrhosis

The Role of Transforming Growth Factor-β in Human Hepatocarcinogenesis: Mechanistic and Therapeutic Implications From an Integrative Multiomics Approach.

The functional cancer map: a systems-level synopsis of genetic deregulation in cancer

The immune contexture of hepatocellular carcinoma predicts clinical outcome

The impact of patient and tumour baseline characteristics on the overall survival of patients with advanced hepatocellular carcinoma treated with sorafenib.

The role of molecular enrichment on future therapies in hepatocellular carcinoma

Transarterial chemoembolization versus sorafenib in patients with hepatocellular carcinoma and extrahepatic disease

Translating bioinformatics in oncology: guilt-by-profiling analysis and identification of KIF18B and CDCA3 as novel driver genes in carcinogenesis

Treatment and survival of non-alcoholic steatohepatitis associated hepatocellular carcinoma

Use of inhibitors of the renin-angiotensin system is associated with longer survival in patients with hepatocellular carcinoma

Validation of the simplified Animal Naming Test as primary screening tool for the diagnosis of covert hepatic encephalopathy

YAP-dependent induction of UHMK1 supports nuclear enrichment of the oncogene MYBL2 and proliferation in liver cancer cells

[Etiology and complications of liver cirrhosis: data from a German centre].

[Hepatocellular carcinoma: molecular pathogenesis and novel targets for therapy]

[Hepatocellular carcinoma: what's new?]

[Hepatocellular carcinoma]

[Personalised hepatology - current concepts, developments and expectations in the post-genome era]

[Response to Terlipressin and albumin is associated with improved outcome in patients with cirrhosis and hepatorenal syndrome]