Lista de obras - Nicholas C.O. Tomkinson - Dominio Público Uruguay

A General Method for the α-Acyloxylation of Carbonyl Compounds

artículo científico publicado en 2005

A Photoaffinity Displacement Assay and Probes to Study the Cyclin-Dependent Kinase Family

scientific article published on 31 October 2019

A Scalable Metal-, Azide-, and Halogen-Free Method for the Preparation of Triazoles

artículo científico publicado en 2020

A cluster of palmitoylated cysteines are essential for aggregation of cysteine-string protein mutants that cause neuronal ceroid lipofuscinosis.

artículo científico publicado en 2017

A new class of ratiometric small molecule intracellular pH sensors for Raman microscopy

scientific article published on 16 July 2020

A simple method for the alpha-oxygenation of aldehydes.

artículo científico publicado en 2005

Advancements in the Development of non-BET Bromodomain Chemical Probes

scientific article published on 04 February 2019

Alkene Dioxygenation with Malonoyl Peroxides: Synthesis of γ-Lactones, Isobenzofuranones, and Tetrahydrofurans

artículo científico publicado en 2016

Alkene Oxyamination Using Malonoyl Peroxides: Preparation of Pyrrolidines and Isoxazolidines

artículo científico publicado en 2018

Alkene Syn- and Anti-Oxyamination with Malonoyl Peroxides

artículo científico publicado en 2020

Alkene anti-Dihydroxylation with Malonoyl Peroxides

artículo científico publicado en 2015

Alkene syn dihydroxylation with malonoyl peroxides.

artículo científico publicado en 2010

Aminocatalytic preparation of bisindolylalkanes

scientific article published on 12 October 2005

Arene oxidation with malonoyl peroxides

artículo científico publicado en 2015

Asymmetric α-oxyacylation of cyclic ketones

artículo científico publicado en 2012

Circadian clock component REV-ERBα controls homeostatic regulation of pulmonary inflammation.

artículo científico publicado en 2018

Clinical progress and pharmacology of small molecule bromodomain inhibitors.

artículo científico publicado en 2016

Computational study of iminium ion formation: effects of amine structure

scientific article published on 01 June 2006

Copper-catalysed C-H functionalisation gives access to 2-aminobenzimidazoles

scientific article published on 01 August 2019

Copper-catalyzed coupling of hydroxylamines with aryl iodides.

artículo científico publicado en 2008

Differential activity of rosiglitazone enantiomers at PPAR gamma

artículo científico publicado en 1998

Direct alpha-oxytosylation of carbonyl compounds: one-pot synthesis of heterocycles

artículo científico publicado en 2007

Enhanced pi ... pi interactions in alpha,beta-unsaturated carbonyls.

artículo científico publicado en 2003

Fam49/CYRI interacts with Rac1 and locally suppresses protrusions

artículo científico publicado en 2018

Further studies on the synthesis of 24(S),25-epoxycholesterol. A new, efficient preparation of desmosterol

scientific article published on 01 April 2000

Identification of key features required for efficient S-acylation and plasma membrane targeting of Sprouty-2

artículo científico publicado en 2020

Identification of peroxisome proliferator-activated receptor ligands from a biased chemical library.

artículo científico publicado en 1997

Iminium ion catalysis: direct comparison of imidazolidinone and diarylprolinol ether reactivity

Iminium ion catalysis: use of the alpha-effect in the acceleration of the Diels-Alder reaction

scientific article published on 01 March 2003

Improving catalyst activity in secondary amine catalysed transformations

artículo científico publicado en 2015

Inhibition of the ULK1 protein complex suppresses Staphylococcus-induced autophagy and cell death

artículo científico publicado en 2019

Kinetics of iminium ion catalysis.

artículo científico publicado en 2008

Metal Triflate-Promoted Allylic Substitution Reactions of Cinnamyl Alcohol in the Presence of Orthoesters and Acetals

artículo científico publicado en 2019

Metal-free dihydroxylation of alkenes using cyclobutane malonoyl peroxide.

artículo científico publicado en 2012

Microwave-assisted synthesis of 3-aminobenzo[b]thiophene scaffolds for the preparation of kinase inhibitors.

artículo científico publicado en 2015

Mitokyne: A Ratiometric Raman Probe for Mitochondrial pH

artículo científico publicado en 2021

Molecular basis of fatty acid selectivity in the zDHHC family of S-acyltransferases revealed by click chemistry.

artículo científico publicado en 2017

On the roles of protic solvents in imidazolidinone-catalyzed transformations

artículo científico publicado en 2011

Palladium-catalyzed coupling of hydroxylamines with aryl bromides, chlorides, and iodides

scientific article published on 01 January 2009

Progress in the Development of non-BET Bromodomain Chemical Probes

artículo científico publicado en 2016

Ratiometric sensing of fluoride ions using Raman spectroscopy

scientific article published on 04 November 2020

Readily accessible chiral at nitrogen cage structures

artículo científico publicado en 2013

Rearrangement strategy for the synthesis of 2-aminoanilines.

artículo científico publicado en 2010

Regioselective Reaction of Heterocyclic N-Oxides, an Acyl Chloride, and Cyclic Thioethers.

artículo científico publicado en 2018

Regioselective Three-Component Reaction of Pyridine N-Oxides, Acyl Chlorides, and Cyclic Ethers.

artículo científico publicado en 2017

Secondary and primary amine catalysts for iminium catalysis.

artículo científico publicado en 2010

Solution phase, solid state, and theoretical investigations on the MacMillan imidazolidinone.

artículo científico publicado en 2009

Stereoselective Synthesis of Alkylidene Phthalides

artículo científico publicado en 2016

Stimulated Raman scattering microscopy with spectral phasor analysis: applications in assessing drug–cell interactions

artículo científico publicado en 2022

Synthesis of dibenzylamino-1-methylcyclohexanol and dibenzylamino-1-trifluoromethylcyclohexanol isomers

artículo científico publicado en 2016

Temporal imaging of drug dynamics in live cells using stimulated Raman scattering microscopy and a perfusion cell culture system

artículo científico publicado en 2022

The α-effect in cyclic secondary amines: new scaffolds for iminium ion accelerated transformations

article

The α-effect in iminium ion catalysis

Tracking intracellular uptake and localisation of alkyne tagged fatty acids using Raman spectroscopy

artículo científico publicado en 2018

Lista de obras de Nicholas C.O. Tomkinson

A General Method for the α-Acyloxylation of Carbonyl Compounds

A Photoaffinity Displacement Assay and Probes to Study the Cyclin-Dependent Kinase Family

A Scalable Metal-, Azide-, and Halogen-Free Method for the Preparation of Triazoles

A cluster of palmitoylated cysteines are essential for aggregation of cysteine-string protein mutants that cause neuronal ceroid lipofuscinosis.

A new class of ratiometric small molecule intracellular pH sensors for Raman microscopy

A simple method for the alpha-oxygenation of aldehydes.

Advancements in the Development of non-BET Bromodomain Chemical Probes

Alkene Dioxygenation with Malonoyl Peroxides: Synthesis of γ-Lactones, Isobenzofuranones, and Tetrahydrofurans

Alkene Oxyamination Using Malonoyl Peroxides: Preparation of Pyrrolidines and Isoxazolidines

Alkene Syn- and Anti-Oxyamination with Malonoyl Peroxides

Alkene anti-Dihydroxylation with Malonoyl Peroxides

Alkene syn dihydroxylation with malonoyl peroxides.

Aminocatalytic preparation of bisindolylalkanes

Arene oxidation with malonoyl peroxides

Asymmetric α-oxyacylation of cyclic ketones

Circadian clock component REV-ERBα controls homeostatic regulation of pulmonary inflammation.

Clinical progress and pharmacology of small molecule bromodomain inhibitors.

Computational study of iminium ion formation: effects of amine structure

Copper-catalysed C-H functionalisation gives access to 2-aminobenzimidazoles

Copper-catalyzed coupling of hydroxylamines with aryl iodides.

Differential activity of rosiglitazone enantiomers at PPAR gamma

Direct alpha-oxytosylation of carbonyl compounds: one-pot synthesis of heterocycles

Enhanced pi ... pi interactions in alpha,beta-unsaturated carbonyls.

Fam49/CYRI interacts with Rac1 and locally suppresses protrusions

Further studies on the synthesis of 24(S),25-epoxycholesterol. A new, efficient preparation of desmosterol

Identification of key features required for efficient S-acylation and plasma membrane targeting of Sprouty-2

Identification of peroxisome proliferator-activated receptor ligands from a biased chemical library.

Iminium ion catalysis: direct comparison of imidazolidinone and diarylprolinol ether reactivity

Iminium ion catalysis: use of the alpha-effect in the acceleration of the Diels-Alder reaction

Improving catalyst activity in secondary amine catalysed transformations

Inhibition of the ULK1 protein complex suppresses Staphylococcus-induced autophagy and cell death

Kinetics of iminium ion catalysis.

Metal Triflate-Promoted Allylic Substitution Reactions of Cinnamyl Alcohol in the Presence of Orthoesters and Acetals

Metal-free dihydroxylation of alkenes using cyclobutane malonoyl peroxide.

Microwave-assisted synthesis of 3-aminobenzo[b]thiophene scaffolds for the preparation of kinase inhibitors.

Mitokyne: A Ratiometric Raman Probe for Mitochondrial pH

Molecular basis of fatty acid selectivity in the zDHHC family of S-acyltransferases revealed by click chemistry.

On the roles of protic solvents in imidazolidinone-catalyzed transformations

Palladium-catalyzed coupling of hydroxylamines with aryl bromides, chlorides, and iodides

Progress in the Development of non-BET Bromodomain Chemical Probes

Ratiometric sensing of fluoride ions using Raman spectroscopy

Readily accessible chiral at nitrogen cage structures

Rearrangement strategy for the synthesis of 2-aminoanilines.

Regioselective Reaction of Heterocyclic N-Oxides, an Acyl Chloride, and Cyclic Thioethers.

Regioselective Three-Component Reaction of Pyridine N-Oxides, Acyl Chlorides, and Cyclic Ethers.

Secondary and primary amine catalysts for iminium catalysis.

Solution phase, solid state, and theoretical investigations on the MacMillan imidazolidinone.

Stereoselective Synthesis of Alkylidene Phthalides

Stimulated Raman scattering microscopy with spectral phasor analysis: applications in assessing drug–cell interactions

Synthesis of dibenzylamino-1-methylcyclohexanol and dibenzylamino-1-trifluoromethylcyclohexanol isomers

Temporal imaging of drug dynamics in live cells using stimulated Raman scattering microscopy and a perfusion cell culture system

The α-effect in cyclic secondary amines: new scaffolds for iminium ion accelerated transformations

The α-effect in iminium ion catalysis

Tracking intracellular uptake and localisation of alkyne tagged fatty acids using Raman spectroscopy