Lista de obras - Lucio Miele - Dominio Público Uruguay

17β-estradiol enhances signalling mediated by VEGF-A-delta-like ligand 4-notch1 axis in human endothelial cells

artículo científico publicado en 2013

A magnifying glass on glioblastoma stem cell signaling pathways.

artículo científico publicado en 2011

A novel patient-derived xenograft model for claudin-low triple-negative breast cancer.

artículo científico publicado en 2018

AKT and 14-3-3 regulate Notch4 nuclear localization.

artículo científico publicado en 2015

Aberrant activation of canonical Notch1 signaling in the mouse uterus decreases progesterone receptor by hypermethylation and leads to infertility

artículo científico publicado en 2016

Activation of Notch-1 signaling maintains the neoplastic phenotype in human Ras-transformed cells

artículo científico publicado en 2002

Activation of an endothelial Notch1-Jagged1 circuit induces VCAM1 expression, an effect amplified by interleukin-1β.

artículo científico publicado en 2015

Activation of the A2B adenosine receptor in B16 melanomas induces CXCL12 expression in FAP-positive tumor stromal cells, enhancing tumor progression

artículo científico publicado en 2016

Advancing the Science of Health Disparities Through Research on the Social Determinants of Health

artículo científico publicado en 2017

An Integrative Genomics Approach for Associating GWAS Information with Triple-Negative Breast Cancer.

artículo científico publicado en 2013

An Integrative Genomics Approach for Associating Genome-Wide Association Studies Information With Localized and Metastatic Prostate Cancer Phenotypes

artículo científico publicado en 2017

An integrative genomics approach to biomarker discovery in breast cancer ⬇️

artículo científico publicado el 25 de julio de 2011

Analysis of Patterns of Gene Expression Variation within and between Ethnic Populations in Pediatric B-ALL

artículo científico publicado en 2013

Ancestry as a potential modifier of gene expression in breast tumors from Colombian women.

artículo científico publicado en 2017

Anti-Jagged Immunotherapy Inhibits MDSCs and Overcomes Tumor-Induced Tolerance.

artículo científico publicado en 2017

Arachidonic acid release from NIH 3T3 cells by group‐I phospholipase A2: Involvement of a receptor‐mediated mechanism ⬇️

artículo científico publicado el 1 de diciembre de 1995

Assessing needs and assets for building a regional network infrastructure to reduce cancer related health disparities

artículo científico publicado en 2013

Assessing the Racial and Ethnic Disparities in Breast Cancer Mortality in the United States

artículo científico publicado en 2017

Associating GWAS Information with the Notch Signaling Pathway Using Transcription Profiling.

artículo científico publicado en 2011

Association of Abdominal Visceral Adiposity and Total Fat Mass with Cancer Incidence and Mortality in White and Black Adults

scientific article published in 2022

Atopic dermatitis-like disease and associated lethal myeloproliferative disorder arise from loss of Notch signaling in the murine skin

artículo científico publicado en 2010

Blockade of A2b adenosine receptor reduces tumor growth and immune suppression mediated by myeloid-derived suppressor cells in a mouse model of melanoma.

scientific article published on December 2013

Boronic prodrug of 4-hydroxytamoxifen is more efficacious than tamoxifen with enhanced bioavailability independent of CYP2D6 status

artículo científico publicado en 2015

Boronic prodrug of endoxifen as an effective hormone therapy for breast cancer

artículo científico publicado en 2015

Characterization of tissue specific expression of Notch-1 in human tissues

artículo científico publicado en 2004

Chemoresistance to gemcitabine in hepatoma cells induces epithelial-mesenchymal transition and involves activation of PDGF-D pathway

artículo científico publicado en 2013

Comprehensive assessment and network analysis of the emerging genetic susceptibility landscape of prostate cancer

artículo científico publicado en 2013

Contribution of Notch signaling activation to human glioblastoma multiforme.

artículo científico publicado en 2007

Crosstalk between PKCα and Notch-4 in endocrine-resistant breast cancer cells.

artículo científico publicado en 2013

Cystic fibrosis and phosphatidylcholine biosynthesis

scientific article published on 01 October 1994

Deadly crosstalk: Notch signaling at the intersection of EMT and cancer stem cells.

artículo científico

Decreased Notch pathway signaling in the endometrium of women with endometriosis impairs decidualization.

artículo científico publicado en 2014

Distinct gene expression profiles associated with Notch ligands Delta-like 4 and Jagged1 in plaque material from peripheral artery disease patients: a pilot study

artículo científico publicado en 2017

Diverse and converging roles of ERK1/2 and ERK5 pathways on mesenchymal to epithelial transition in breast cancer

artículo científico publicado en 2021

Down-regulation of Notch-1 is associated with Akt and FoxM1 in inducing cell growth inhibition and apoptosis in prostate cancer cells

artículo científico publicado en 2011

EGCG, a major green tea catechin suppresses breast tumor angiogenesis and growth via inhibiting the activation of HIF-1α and NFκB, and VEGF expression ⬇️

artículo científico publicado el 2 de mayo de 2013

Elevated expression of notch1 is associated with metastasis of human malignancies.

artículo científico publicado en 2013

Emerging roles of PDGF-D in EMT progression during tumorigenesis ⬇️

artículo científico publicado el 20 de diciembre de 2012

Enhancer of zeste homolog 2 (EZH2) in pediatric soft tissue sarcomas: first implications

artículo científico publicado en 2011

Epoxyazadiradione suppresses breast tumor growth through mitochondrial depolarization and caspase-dependent apoptosis by targeting PI3K/Akt pathway

artículo científico publicado en 2018

ErbB-2 inhibition activates Notch-1 and sensitizes breast cancer cells to a gamma-secretase inhibitor

scientific article published on 12 May 2008

Estrogen receptor β-dependent Notch1 activation protects vascular endothelium against tumor necrosis factor α (TNFα)-induced apoptosis

artículo científico publicado en 2017

Expression and distribution of notch protein members in human placenta throughout pregnancy.

artículo científico publicado en 2007

Expression and significance of notch signaling pathway in salivary adenoid cystic carcinoma.

artículo científico publicado en 2013

Farmers' Market Utilization among Supplemental Nutrition Assistance Program Recipients in New Orleans, Louisiana: Preliminary Findings.

artículo científico publicado en 2017

Fulvestrant-3 Boronic Acid (ZB716): An Orally Bioavailable Selective Estrogen Receptor Downregulator (SERD).

artículo científico publicado en 2016

Gamma secretase inhibitor blocks Notch activation and induces apoptosis in Kaposi's sarcoma tumor cells

artículo científico publicado en 2005

Gamma secretase-mediated Notch signaling worsens brain damage and functional outcome in ischemic stroke.

artículo científico publicado en 2006

Genistein Down-Regulates miR-223 Expression in Pancreatic Cancer Cells ⬇️

artículo científico publicado el 1 de septiembre de 2013

HPV16 E6 and E7 oncoproteins regulate Notch-1 expression and cooperate to induce transformation.

artículo científico publicado en 2003

Hedgehog signaling in hepatocellular carcinoma: novel therapeutic strategy targeting hedgehog signaling in HCC

scientific article published on 07 February 2006

High prevalence of luminal B breast cancer intrinsic subtype in Colombian women

artículo científico publicado en 2016

Hyper-activation of Notch3 amplifies the proliferative potential of rhabdomyosarcoma cells.

artículo científico publicado en 2014

Hypoxic Induction of Vasorin Regulates Notch1 Turnover to Maintain Glioma Stem-like Cells

artículo científico publicado en 2017

Increased plasma levels of soluble vascular endothelial growth factor receptor 1 (sFlt-1) in women by moderate exercise and increased plasma levels of vascular endothelial growth factor in overweight/obese women.

artículo científico publicado en 2013

Inhibition of HER2 Increases JAGGED1-dependent Breast Cancer Stem Cells: Role for Membrane JAGGED1

Inhibition of Notch3 signalling induces rhabdomyosarcoma cell differentiation promoting p38 phosphorylation and p21(Cip1) expression and hampers tumour cell growth in vitro and in vivo.

artículo científico publicado en 2011

Inhibitors of gamma-secretase block in vivo and in vitro T helper type 1 polarization by preventing Notch upregulation of Tbx21

artículo científico publicado en 2005

Integrative Analysis of Response to Tamoxifen Treatment in ER-Positive Breast Cancer Using GWAS Information and Transcription Profiling ⬇️

artículo científico publicado el 20 de febrero de 2012

Involvement of notch signaling in wound healing

artículo científico publicado en 2007

Jagged-1 mediated activation of notch signaling induces complete maturation of human keratinocytes through NF-kappaB and PPARgamma

artículo científico publicado en 2002

Lys 43 and Asp 46 in alpha-helix 3 of uteroglobin are essential for its phospholipase A2 inhibitory activity

artículo científico publicado en 2002

Manic fringe promotes a claudin-low breast cancer phenotype through notch-mediated PIK3CG induction.

artículo científico publicado en 2015

MicroRNAs in rhabdomyosarcoma: pathogenetic implications and translational potentiality

artículo científico

Mitochondrial Dysfunction Promotes Breast Cancer Cell Migration and Invasion through HIF1α Accumulation via Increased Production of Reactive Oxygen Species ⬇️

artículo científico publicado el 29 de julio de 2013

Molecular Analysis of Central Nervous System Disease Spectrum in Childhood Acute Lymphoblastic Leukemia.

artículo científico publicado en 2016

Myeloid-derived suppressor cells contribute to A2B adenosine receptor-induced VEGF production and angiogenesis in a mouse melanoma model

artículo científico publicado en 2015

NOTCH-1 and NOTCH-4 are novel gene targets of PEA3 in breast cancer: novel therapeutic implications.

artículo científico publicado en 2011

NOTCH1 Can Initiate NF-κB Activation via Cytosolic Interactions with Components of the T Cell Signalosome

artículo científico publicado en 2014

New weapons against inflammation: dual inhibitors of phospholipase A2 and transglutaminase.

artículo científico publicado en 2003

Non-Canonical Notch Signaling Drives Activation and Differentiation of Peripheral CD4(+) T Cells.

scientific article published on 12 February 2014

Nonradiometric ELISA-based quantitation and validation of polymerase chain reaction-amplified DNA, including detection of point mutations, without allele-specific amplification, or ligation.

artículo científico

Notch Signaling in Myeloid Cells as a Regulator of Tumor Immune Responses.

artículo científico publicado en 2018

Notch Signaling in Neuroendocrine Tumors

artículo científico publicado en 2016

Notch and NOXA-related pathways in melanoma cells.

artículo científico publicado en 2005

Notch and the immune system.

artículo científico publicado en 1999

Notch inhibition in Kaposi's sarcoma tumor cells leads to mitotic catastrophe through nuclear factor-kappaB signaling.

artículo científico publicado en 2007

Notch inhibitors for cancer treatment ⬇️

artículo científico publicado el 28 de febrero de 2013

Notch regulates cytolytic effector function in CD8+ T cells.

artículo científico publicado en 2009

Notch signaling in pediatric soft tissue sarcomas

artículo científico publicado en 2012

Notch signaling is a direct determinant of keratinocyte growth arrest and entry into differentiation

artículo científico publicado en 2001

Notch signaling is necessary but not sufficient for differentiation of dendritic cells.

artículo científico publicado en 2003

Notch signaling regulates mouse and human Th17 differentiation

artículo científico publicado en 2011

Notch signaling.

artículo científico publicado en 2006

Notch signaling: targeting cancer stem cells and epithelial-to-mesenchymal transition

artículo científico publicado en 2013

Notch signals in the endothelium and cancer "stem-like" cells: opportunities for cancer therapy.

artículo científico publicado en 2012

Notch-1 activates estrogen receptor-alpha-dependent transcription via IKKalpha in breast cancer cells.

artículo científico publicado en 2009

Notch-1 associates with IKKalpha and regulates IKK activity in cervical cancer cells.

artículo científico publicado en 2008

Notch-1 induces epithelial-mesenchymal transition consistent with cancer stem cell phenotype in pancreatic cancer cells

artículo científico publicado en 2011

Notch-1 inhibits apoptosis in murine erythroleukemia cells and is necessary for differentiation induced by hybrid polar compounds

artículo científico publicado en 1999

Notch-1 stimulates survival of lung adenocarcinoma cells during hypoxia by activating the IGF-1R pathway.

artículo científico publicado en 2010

Notch-1-PTEN-ERK1/2 signaling axis promotes HER2+ breast cancer cell proliferation and stem cell survival

artículo científico publicado en 2018

Notch-associated microRNAs in cancer.

artículo científico

Notch-independent regulation of Hes-1 expression by c-Jun N-terminal kinase signaling in human endothelial cells

Notch1 is regulated by chorionic gonadotropin and progesterone in endometrial stromal cells and modulates decidualization in primates

artículo científico publicado en 2012

Notch1 mediates uterine stromal differentiation and is critical for complete decidualization in the mouse.

artículo científico publicado en 2011

Notch1 phenotype and clinical stage progression in non-small cell lung cancer

artículo científico publicado en 2015

Notch1 primes CD4 T cells for T helper type I differentiation through its early effects on miR-29

artículo científico publicado en 2018

Notch1 regulates the expression of the multidrug resistance gene ABCC1/MRP1 in cultured cancer cells

artículo científico publicado en 2011

Novel Integrative Genomics Approach for Associating GWAS Information with Intrinsic Subtypes of Breast Cancer.

artículo científico publicado en 2013

Novel putative drivers revealed by targeted exome sequencing of advanced solid tumors.

artículo científico publicado en 2018

OX40L/Jagged1 Cosignaling by GM-CSF–Induced Bone Marrow-Derived Dendritic Cells Is Required for the Expansion of Functional Regulatory T Cells ⬇️

artículo científico publicado el 29 de abril de 2013

Off the beaten pathway: the complex cross talk between Notch and NF-kappaB

artículo científico publicado en 2007

Over-expression of FoxM1 leads to epithelial-mesenchymal transition and cancer stem cell phenotype in pancreatic cancer cells

artículo científico publicado en 2011

Overexpression of the NOTCH ligand JAG2 in malignant plasma cells from multiple myeloma patients and cell lines.

artículo científico publicado en 2004

Oxygen concentration determines the biological effects of NOTCH-1 signaling in adenocarcinoma of the lung.

artículo científico publicado en 2007

PKCα Attenuates Jagged-1-Mediated Notch Signaling in ErbB-2-Positive Breast Cancer to Reverse Trastuzumab Resistance

artículo científico publicado en 2015

Phospholipase A2 enzymes: regulation and physiological role.

artículo científico publicado en 1994

Plants as bioreactors for biopharmaceuticals: regulatory considerations.

artículo científico publicado en 1997

Postmenopausal obesity promotes tumor angiogenesis and breast cancer progression in mice

artículo científico publicado en 2011

Proteasome inhibitors trigger NOXA-mediated apoptosis in melanoma and myeloma cells

artículo científico publicado en 2005

Proteomic-based Analysis for Identification of Proteins Involved in 5-fluorouracil Resistance in Hepatocellular Carcinoma ⬇️

artículo científico publicado el 1 de enero de 2014

Racial Disparities and Preventive Measures to Renal Cell Carcinoma.

artículo científico publicado en 2018

Rational targeting of Notch signaling in breast cancer

artículo científico publicado en 2008

Recombinant human uteroglobin suppresses cellular invasiveness via a novel class of high-affinity cell surface binding site.

artículo científico publicado en 1996

Recombinant human uteroglobin/CC10 inhibits the adhesion and migration of primary human endothelial cells via specific and saturable binding to fibronectin

artículo científico publicado en 2006

Resonance assignment and secondary structure determination and stability of the recombinant human uteroglobin with heteronuclear multidimensional NMR.

artículo científico publicado en 1997

Retracted: Activated K-ras and INK4a/Arf Deficiency Cooperate During the Development of Pancreatic Cancer by Activation of Notch and NF-κB Signaling Pathways

artículo científico publicado en 2011

SU11248, A selective tyrosine kinases inhibitor suppresses breast tumor angiogenesis and growth via targeting both tumor vasculature and breast cancer cells ⬇️

artículo científico publicado el 1 de octubre de 2010

SV40 and human brain tumors

artículo científico publicado en 2003

Serum From Advanced Heart Failure Patients Promotes Angiogenic Sprouting and Affects the Notch Pathway in Human Endothelial Cells

artículo científico publicado en 2016

Sirt2 deacetylase is a novel AKT binding partner critical for AKT activation by insulin

artículo científico publicado en 2014

Sunitinib significantly suppresses the proliferation, migration, apoptosis resistance, tumor angiogenesis and growth of triple-negative breast cancers but increases breast cancer stem cells

artículo científico publicado en 2014

Systems Biology Approaches in Identifying the Targets of Natural Compounds for Cancer Therapy ⬇️

artículo científico publicado el 1 de junio de 2013

Targeting Met and Notch in the Lfng-deficient, Met-amplified triple-negative breast cancer.

artículo científico publicado en 2014

Targeting Notch in oncology: the path forward

artículo científico publicado en 2020

Targeting Notch to target cancer stem cells.

scientific article published on 08 June 2010

Targeting Notch, Hedgehog, and Wnt pathways in cancer stem cells: clinical update

artículo científico publicado en 2015

Targeting pancreatic cancer stem cells for cancer therapy ⬇️

artículo científico publicado el 20 de junio de 2012

Targeting the NF-kappaB signaling pathway in Notch1-induced T-cell leukemia.

artículo científico publicado en 2006

Targeting the adenosine A2b receptor in the tumor microenvironment overcomes local immunosuppression by myeloid-derived suppressor cells.

artículo científico publicado en 2014

The Notch ligand Jagged-1 is able to induce maturation of monocyte-derived human dendritic cells

artículo científico publicado en 2002

The Notch pathway: a crossroad between the life and death of the endothelium ⬇️

artículo científico publicado el 29 de mayo de 2012

The Polycomb group (PcG) protein EZH2 supports the survival of PAX3-FOXO1 alveolar rhabdomyosarcoma by repressing FBXO32 (Atrogin1/MAFbx).

artículo científico publicado en 2013

The role of chorionic gonadotropin and Notch1 in implantation

artículo científico publicado en 2007

The sphingosine kinase 2 inhibitor ABC294640 displays anti-non-small cell lung cancer activities in vitro and in vivo.

artículo científico publicado en 2017

Therapeutic targeting of NOTCH signaling ameliorates immune-mediated bone marrow failure of aplastic anemia

artículo científico publicado en 2013

Transcription factor RBPJ/CSL: A genome-wide look at transcriptional regulation ⬇️

artículo científico publicado el 24 de agosto de 2011

Tumor cell-mediated neovascularization and lymphangiogenesis contrive tumor progression and cancer metastasis ⬇️

artículo científico publicado el 8 de agosto de 2013

Unraveling the mystery of cancer metabolism in the genesis of tumor-initiating cells and development of cancer ⬇️

artículo científico publicado el 21 de marzo de 2013

Uteroglobin, a possible ligand of the lipoxin receptor inhibits serum amyloid A-driven inflammation.

artículo científico publicado en 2014

Whole Genome Transcriptome Analysis of the Association between Obesity and Triple-Negative Breast Cancer in Caucasian Women

artículo científico publicado en 2018

ZB716, a steroidal selective estrogen receptor degrader (SERD), is orally efficacious in blocking tumor growth in mouse xenograft models.

artículo científico publicado en 2018

p53 Modulates Notch Signaling in MCF-7 Breast Cancer Cells by Associating With the Notch Transcriptional Complex Via MAML1

artículo científico publicado en 2015

γ-Secretase inhibitors and modulators ⬇️

artículo científico publicado el 17 de junio de 2013

γ-Secretase inhibitors in cancer clinical trials are pharmacologically and functionally distinct

artículo científico publicado en 2017

Lista de obras de Lucio Miele

17β-estradiol enhances signalling mediated by VEGF-A-delta-like ligand 4-notch1 axis in human endothelial cells

A magnifying glass on glioblastoma stem cell signaling pathways.

A novel patient-derived xenograft model for claudin-low triple-negative breast cancer.

AKT and 14-3-3 regulate Notch4 nuclear localization.

Aberrant activation of canonical Notch1 signaling in the mouse uterus decreases progesterone receptor by hypermethylation and leads to infertility

Activation of Notch-1 signaling maintains the neoplastic phenotype in human Ras-transformed cells

Activation of an endothelial Notch1-Jagged1 circuit induces VCAM1 expression, an effect amplified by interleukin-1β.

Activation of the A2B adenosine receptor in B16 melanomas induces CXCL12 expression in FAP-positive tumor stromal cells, enhancing tumor progression

Advancing the Science of Health Disparities Through Research on the Social Determinants of Health

An Integrative Genomics Approach for Associating GWAS Information with Triple-Negative Breast Cancer.

An Integrative Genomics Approach for Associating Genome-Wide Association Studies Information With Localized and Metastatic Prostate Cancer Phenotypes

An integrative genomics approach to biomarker discovery in breast cancer ⬇️

Analysis of Patterns of Gene Expression Variation within and between Ethnic Populations in Pediatric B-ALL

Ancestry as a potential modifier of gene expression in breast tumors from Colombian women.

Anti-Jagged Immunotherapy Inhibits MDSCs and Overcomes Tumor-Induced Tolerance.

Arachidonic acid release from NIH 3T3 cells by group‐I phospholipase A2: Involvement of a receptor‐mediated mechanism ⬇️

Assessing needs and assets for building a regional network infrastructure to reduce cancer related health disparities

Assessing the Racial and Ethnic Disparities in Breast Cancer Mortality in the United States

Associating GWAS Information with the Notch Signaling Pathway Using Transcription Profiling.

Association of Abdominal Visceral Adiposity and Total Fat Mass with Cancer Incidence and Mortality in White and Black Adults

Atopic dermatitis-like disease and associated lethal myeloproliferative disorder arise from loss of Notch signaling in the murine skin

Blockade of A2b adenosine receptor reduces tumor growth and immune suppression mediated by myeloid-derived suppressor cells in a mouse model of melanoma.

Boronic prodrug of 4-hydroxytamoxifen is more efficacious than tamoxifen with enhanced bioavailability independent of CYP2D6 status

Boronic prodrug of endoxifen as an effective hormone therapy for breast cancer

Characterization of tissue specific expression of Notch-1 in human tissues

Chemoresistance to gemcitabine in hepatoma cells induces epithelial-mesenchymal transition and involves activation of PDGF-D pathway

Comprehensive assessment and network analysis of the emerging genetic susceptibility landscape of prostate cancer

Contribution of Notch signaling activation to human glioblastoma multiforme.

Crosstalk between PKCα and Notch-4 in endocrine-resistant breast cancer cells.

Cystic fibrosis and phosphatidylcholine biosynthesis

Deadly crosstalk: Notch signaling at the intersection of EMT and cancer stem cells.

Decreased Notch pathway signaling in the endometrium of women with endometriosis impairs decidualization.

Distinct gene expression profiles associated with Notch ligands Delta-like 4 and Jagged1 in plaque material from peripheral artery disease patients: a pilot study

Diverse and converging roles of ERK1/2 and ERK5 pathways on mesenchymal to epithelial transition in breast cancer

Down-regulation of Notch-1 is associated with Akt and FoxM1 in inducing cell growth inhibition and apoptosis in prostate cancer cells

EGCG, a major green tea catechin suppresses breast tumor angiogenesis and growth via inhibiting the activation of HIF-1α and NFκB, and VEGF expression ⬇️

Elevated expression of notch1 is associated with metastasis of human malignancies.

Emerging roles of PDGF-D in EMT progression during tumorigenesis ⬇️

Enhancer of zeste homolog 2 (EZH2) in pediatric soft tissue sarcomas: first implications

Epoxyazadiradione suppresses breast tumor growth through mitochondrial depolarization and caspase-dependent apoptosis by targeting PI3K/Akt pathway

ErbB-2 inhibition activates Notch-1 and sensitizes breast cancer cells to a gamma-secretase inhibitor

Estrogen receptor β-dependent Notch1 activation protects vascular endothelium against tumor necrosis factor α (TNFα)-induced apoptosis

Expression and distribution of notch protein members in human placenta throughout pregnancy.

Expression and significance of notch signaling pathway in salivary adenoid cystic carcinoma.

Farmers' Market Utilization among Supplemental Nutrition Assistance Program Recipients in New Orleans, Louisiana: Preliminary Findings.

Fulvestrant-3 Boronic Acid (ZB716): An Orally Bioavailable Selective Estrogen Receptor Downregulator (SERD).

Gamma secretase inhibitor blocks Notch activation and induces apoptosis in Kaposi's sarcoma tumor cells

Gamma secretase-mediated Notch signaling worsens brain damage and functional outcome in ischemic stroke.

Genistein Down-Regulates miR-223 Expression in Pancreatic Cancer Cells ⬇️

HPV16 E6 and E7 oncoproteins regulate Notch-1 expression and cooperate to induce transformation.

Hedgehog signaling in hepatocellular carcinoma: novel therapeutic strategy targeting hedgehog signaling in HCC

High prevalence of luminal B breast cancer intrinsic subtype in Colombian women

Hyper-activation of Notch3 amplifies the proliferative potential of rhabdomyosarcoma cells.

Hypoxic Induction of Vasorin Regulates Notch1 Turnover to Maintain Glioma Stem-like Cells

Increased plasma levels of soluble vascular endothelial growth factor receptor 1 (sFlt-1) in women by moderate exercise and increased plasma levels of vascular endothelial growth factor in overweight/obese women.

Inhibition of HER2 Increases JAGGED1-dependent Breast Cancer Stem Cells: Role for Membrane JAGGED1

Inhibition of Notch3 signalling induces rhabdomyosarcoma cell differentiation promoting p38 phosphorylation and p21(Cip1) expression and hampers tumour cell growth in vitro and in vivo.

Inhibitors of gamma-secretase block in vivo and in vitro T helper type 1 polarization by preventing Notch upregulation of Tbx21

Integrative Analysis of Response to Tamoxifen Treatment in ER-Positive Breast Cancer Using GWAS Information and Transcription Profiling ⬇️

Involvement of notch signaling in wound healing

Jagged-1 mediated activation of notch signaling induces complete maturation of human keratinocytes through NF-kappaB and PPARgamma

Lys 43 and Asp 46 in alpha-helix 3 of uteroglobin are essential for its phospholipase A2 inhibitory activity

Manic fringe promotes a claudin-low breast cancer phenotype through notch-mediated PIK3CG induction.

MicroRNAs in rhabdomyosarcoma: pathogenetic implications and translational potentiality

Mitochondrial Dysfunction Promotes Breast Cancer Cell Migration and Invasion through HIF1α Accumulation via Increased Production of Reactive Oxygen Species ⬇️

Molecular Analysis of Central Nervous System Disease Spectrum in Childhood Acute Lymphoblastic Leukemia.

Myeloid-derived suppressor cells contribute to A2B adenosine receptor-induced VEGF production and angiogenesis in a mouse melanoma model

NOTCH-1 and NOTCH-4 are novel gene targets of PEA3 in breast cancer: novel therapeutic implications.

NOTCH1 Can Initiate NF-κB Activation via Cytosolic Interactions with Components of the T Cell Signalosome

New weapons against inflammation: dual inhibitors of phospholipase A2 and transglutaminase.

Non-Canonical Notch Signaling Drives Activation and Differentiation of Peripheral CD4(+) T Cells.

Nonradiometric ELISA-based quantitation and validation of polymerase chain reaction-amplified DNA, including detection of point mutations, without allele-specific amplification, or ligation.

Notch Signaling in Myeloid Cells as a Regulator of Tumor Immune Responses.

Notch Signaling in Neuroendocrine Tumors

Notch and NOXA-related pathways in melanoma cells.

Notch and the immune system.

Notch inhibition in Kaposi's sarcoma tumor cells leads to mitotic catastrophe through nuclear factor-kappaB signaling.

Notch inhibitors for cancer treatment ⬇️

Notch regulates cytolytic effector function in CD8+ T cells.