Lista de obras - Sonia Severin - Dominio Público Uruguay

A confocal-based morphometric analysis shows a functional crosstalk between the actin filament system and microtubules in thrombin-stimulated platelets

scientific article published on 01 January 2013

A dual role for the class III PI3K, Vps34, in platelet production and thrombus growth.

artículo científico publicado en 2017

A novel mass assay to quantify the bioactive lipid PtdIns3P in various biological samples

artículo científico publicado en 2012

ATP-binding cassette transporter 1 (ABCA1) deficiency decreases platelet reactivity and reduces thromboxane A2 production independently of hematopoietic ABCA1.

artículo científico publicado en 2016

Catalytic dysregulation of SHP2 leading to Noonan syndromes affects platelet signaling and functions

artículo científico publicado en 2019

Cdc42-dependent F-actin dynamics drive structuration of the demarcation membrane system in megakaryocytes

artículo científico publicado en 2016

Class I PI 3-kinases signaling in platelet activation and thrombosis: PDK1/Akt/GSK3 axis and impact of PTEN and SHIP1.

artículo científico

Critical role for ERK1/2 in bone marrow and fetal liver-derived primary megakaryocyte differentiation, motility, and proplatelet formation

artículo científico publicado en 2009

Deficiency of Src homology 2 domain-containing inositol 5-phosphatase 1 affects platelet responses and thrombus growth

artículo científico publicado en 2007

Different roles of SHIP1 according to the cell context: the example of blood platelets.

artículo científico publicado en 2007

Disrupting the platelet internal membrane via PI3KC2α inhibition impairs thrombosis independently of canonical platelet activation

artículo científico publicado en 2020

Distinct and overlapping functional roles of Src family kinases in mouse platelets

artículo científico publicado en 2012

Effects of Estrogens on Platelets and Megakaryocytes

scientific article published on 25 June 2019

Essential role of class II PI3K-C2α in platelet membrane morphology

artículo científico publicado en 2015

Expression of myotubularins in blood platelets: Characterization and potential diagnostic of X-linked myotubular myopathy.

artículo científico publicado en 2016

JAK2V617F leads to intrinsic changes in platelet formation and reactivity in a knock-in mouse model of essential thrombocythemia

artículo científico publicado en 2013

Megakaryocyte-restricted MYH9 inactivation dramatically affects hemostasis while preserving platelet aggregation and secretion.

artículo científico publicado en 2007

Phosphatidylinositol 3 monophosphate metabolizing enzymes in blood platelet production and in thrombosis

artículo científico publicado en 2019

Phosphoinositides: Important lipids in the coordination of cell dynamics

artículo científico

Platelet PI3Kβ and GSK3 regulate thrombus stability at a high shear rate.

artículo científico publicado en 2014

Profiling of phosphoinositide molecular species in human and mouse platelets identifies new species increasing following stimulation

artículo científico publicado en 2018

Protein kinase Cε and protein kinase Cθ double-deficient mice have a bleeding diathesis.

artículo científico publicado en 2012

Proteomic analysis of integrin alphaIIbbeta3 outside-in signaling reveals Src-kinase-independent phosphorylation of Dok-1 and Dok-3 leading to SHIP-1 interactions

artículo científico publicado en 2009

Roles of the C-terminal tyrosine residues of LAT in GPVI-induced platelet activation: insights into the mechanism of PLC gamma 2 activation

scientific journal article

Src family kinases are essential for primary aggregation by G(i) -coupled receptors

artículo científico publicado en 2010

Syk-dependent phosphorylation of CLEC-2: a novel mechanism of hem-immunoreceptor tyrosine-based activation motif signaling

artículo científico publicado en 2010

Targeting Kinases in Cancer Therapies: Adverse Effects on Blood Platelets.

artículo científico publicado en 2016

The importance of blood platelet lipid signaling in thrombosis and in sepsis.

artículo científico publicado en 2017

The mitogen-activated protein kinase signaling pathways: role in megakaryocyte differentiation

artículo científico publicado en 2009

The role of class I, II and III PI 3-kinases in platelet production and activation and their implication in thrombosis

artículo científico

Lista de obras de Sonia Severin

A confocal-based morphometric analysis shows a functional crosstalk between the actin filament system and microtubules in thrombin-stimulated platelets

A dual role for the class III PI3K, Vps34, in platelet production and thrombus growth.

A novel mass assay to quantify the bioactive lipid PtdIns3P in various biological samples

ATP-binding cassette transporter 1 (ABCA1) deficiency decreases platelet reactivity and reduces thromboxane A2 production independently of hematopoietic ABCA1.

Catalytic dysregulation of SHP2 leading to Noonan syndromes affects platelet signaling and functions

Cdc42-dependent F-actin dynamics drive structuration of the demarcation membrane system in megakaryocytes

Class I PI 3-kinases signaling in platelet activation and thrombosis: PDK1/Akt/GSK3 axis and impact of PTEN and SHIP1.

Critical role for ERK1/2 in bone marrow and fetal liver-derived primary megakaryocyte differentiation, motility, and proplatelet formation

Deficiency of Src homology 2 domain-containing inositol 5-phosphatase 1 affects platelet responses and thrombus growth

Different roles of SHIP1 according to the cell context: the example of blood platelets.

Disrupting the platelet internal membrane via PI3KC2α inhibition impairs thrombosis independently of canonical platelet activation

Distinct and overlapping functional roles of Src family kinases in mouse platelets

Effects of Estrogens on Platelets and Megakaryocytes

Essential role of class II PI3K-C2α in platelet membrane morphology

Expression of myotubularins in blood platelets: Characterization and potential diagnostic of X-linked myotubular myopathy.

JAK2V617F leads to intrinsic changes in platelet formation and reactivity in a knock-in mouse model of essential thrombocythemia

Megakaryocyte-restricted MYH9 inactivation dramatically affects hemostasis while preserving platelet aggregation and secretion.

Phosphatidylinositol 3 monophosphate metabolizing enzymes in blood platelet production and in thrombosis

Phosphoinositides: Important lipids in the coordination of cell dynamics

Platelet PI3Kβ and GSK3 regulate thrombus stability at a high shear rate.

Profiling of phosphoinositide molecular species in human and mouse platelets identifies new species increasing following stimulation

Protein kinase Cε and protein kinase Cθ double-deficient mice have a bleeding diathesis.

Proteomic analysis of integrin alphaIIbbeta3 outside-in signaling reveals Src-kinase-independent phosphorylation of Dok-1 and Dok-3 leading to SHIP-1 interactions

Roles of the C-terminal tyrosine residues of LAT in GPVI-induced platelet activation: insights into the mechanism of PLC gamma 2 activation

Src family kinases are essential for primary aggregation by G(i) -coupled receptors

Syk-dependent phosphorylation of CLEC-2: a novel mechanism of hem-immunoreceptor tyrosine-based activation motif signaling

Targeting Kinases in Cancer Therapies: Adverse Effects on Blood Platelets.

The importance of blood platelet lipid signaling in thrombosis and in sepsis.

The mitogen-activated protein kinase signaling pathways: role in megakaryocyte differentiation

The role of class I, II and III PI 3-kinases in platelet production and activation and their implication in thrombosis