Filtros de búsqueda

Lista de obras de A. Cecile Janssens

'It might happen or it might not': how patients with multiple sclerosis explain their perception of prognostic risk

artículo científico publicado en 2004

A K(ATP) channel gene effect on sleep duration: from genome-wide association studies to function in Drosophila

artículo científico publicado en 2011

A collaborative translational research framework for evaluating and implementing the appropriate use of human genome sequencing to improve health

article

A critical appraisal of the scientific basis of commercial genomic profiles used to assess health risks and personalize health interventions

artículo científico publicado en 2008

A critical evaluation of the algorithm behind the Relative Citation Ratio (RCR).

artículo científico publicado en 2017

A genome-wide linkage study of individuals with high scores on NEO personality traits

artículo científico publicado en 2011

A genome-wide screen for depression in two independent Dutch populations

artículo científico publicado en 2010

A methodological perspective on genetic risk prediction studies in type 2 diabetes: recommendations for future research

artículo científico publicado en 2011

A new logistic regression approach for the evaluation of diagnostic test results

artículo científico publicado en 2005

A study of the SORL1 gene in Alzheimer's disease and cognitive function

artículo científico publicado en 2009

A systematic review and critical assessment of 11 discordant meta-analyses on reduced-function CYP2C19 genotype and risk of adverse clinical outcomes in clopidogrel users

artículo científico publicado en 2014

A tiered-layered-staged model for informed consent in personal genome testing ⬇️

artículo científico publicado el 21 de noviembre de 2012

Accuracy of self-reported family history is strongly influenced by the accuracy of self-reported personal health status of relatives

artículo científico publicado en 2011

Adaptation is favorable for most patients with multiple sclerosis

artículo científico publicado en 2004

An Electrocardiogram-Based Risk Equation for Incident Cardiovascular Disease From the National Health and Nutrition Examination Survey

artículo científico publicado en 2016

An empirical comparison of meta-analyses of published gene-disease associations versus consortium analyses

artículo científico publicado en 2009

Analytical and simulation methods for estimating the potential predictive ability of genetic profiling: a comparison of methods and results

artículo científico publicado en 2012

Angiotensinogen M235T polymorphism and symptoms of depression in a population-based study and a family-based study

artículo científico publicado en 2008

Anxiety and depression after prostate cancer diagnosis and treatment: 5-year follow-up.

artículo científico publicado en 2006

Anxiety and depression influence the relation between disability status and quality of life in multiple sclerosis

artículo científico publicado en 2003

Apolipoprotein E gene is related to mortality only in normal weight individuals: the Rotterdam Study

artículo científico publicado en 2007

Assessing predictive performance beyond the Framingham risk score.

artículo científico publicado en 2010

Assessment of Improved Prediction Beyond Traditional Risk Factors

scientific article published on 01 February 2010

Assessment of pharmacogenetic tests: presenting measures of clinical validity and potential population impact in association studies

artículo científico publicado en 2016

B-type natriuretic peptide and C-reactive protein in the prediction of atrial fibrillation risk: the CHARGE-AF Consortium of community-based cohort studies

artículo científico publicado en 2014

Biological, clinical and population relevance of 95 loci for blood lipids

artículo científico publicado en 2010

CHOLESTERYL ESTER TRANSFER PROTEIN GENE AND CORONARY HEART DISEASE MORTALITY: THE ROTTERDAM STUDY

article

CSF tests in the differential diagnosis of Creutzfeldt-Jakob disease.

artículo científico publicado en 2006

Callosal lesion predicts future attacks after clinically isolated syndrome.

artículo científico publicado en 2009

Carriage of reduced-function CYP2C19 allele among patients treated with clopidogrel

artículo científico publicado en 2011

Clinical Implications of Old and New Genes for Open-Angle Glaucoma

article

Comparison of participant information and informed consent forms of five European studies in genetic isolated populations

artículo científico publicado en 2010

Constructing Hypothetical Risk Data from the Area under the ROC Curve: Modelling Distributions of Polygenic Risk

artículo científico publicado en 2016

Correction: A collaborative translational research framework for evaluating and implementing the appropriate use of human genome sequencing to improve health

article

Cost Effectiveness of Age-specific Screening Intervals for People With Family Histories of Colorectal Cancer

artículo científico publicado en 2017

Cost-Effectiveness of Risk-Stratified Colorectal Cancer Screening Based on Polygenic Risk: Current Status and Future Potential

scientific article published on 14 October 2019

Cox proportional hazards models have more statistical power than logistic regression models in cross-sectional genetic association studies

article

Defining Evidence for Precision Medicine: A Patient Is More Than a Set of Covariates

scientific article published on 01 May 2019

Designing babies through gene editing: science or science fiction?

artículo científico publicado en 2016

Discriminative accuracy of genomic profiling comparing multiplicative and additive risk models

artículo científico publicado en 2010

Divorce and unemployment in multiple sclerosis: recalculation of the data of Morales-Gonzáles J M, Benito-Leon J, Rivera-Navarro J and Mitchell A J.

artículo científico publicado en 2004

Does genetic testing really improve the prediction of future type 2 diabetes?

artículo científico publicado en 2006

Early Age at Menopause is Associated with Increased risk of Dementia and Mortality in Women with Down Syndrome

artículo científico publicado en 2010

Erratum

scholarly article published in Medical Decision Making

Erratum to: Novel citation-based search method for scientific literature: application to meta-analyses

artículo científico publicado en 2015

Estimating the predictive ability of genetic risk models in simulated data based on published results from genome-wide association studies

artículo científico publicado en 2014

Ethnic differences and parental beliefs are important for overweight prevention and management in children: a cross-sectional study in the Netherlands

artículo científico publicado en 2012

Ethnicity, educational level and attitudes contribute to parental intentions about genetic testing for child obesity

artículo científico publicado en 2013

Evaluation of polygenic risk models using multiple performance measures: a critical assessment of discordant results.

artículo científico publicado en 2018

Evaluation of risk prediction updates from commercial genome-wide scans

article by Raluca Mihaescu et al published 25 July 2009 in Genetics in Medicine

Expectations of wheelchair-dependency in recently diagnosed patients with multiple sclerosis and their partners

artículo científico publicado en 2003

External validation is only needed when prediction models are worth it (Letter commenting on: J Clin Epidemiol. 2015;68:25-34).

artículo científico publicado en 2015

Eye color and the prediction of complex phenotypes from genotypes.

artículo científico publicado en 2009

Family history and the natural history of colorectal cancer: systematic review

artículo científico publicado en 2015

Fatigue: an important feature of late-onset Pompe disease

artículo científico publicado en 2007

Finding Wealth in Waste: Irreplicability Re-Examined

Five genetic variants associated with prostate cancer

scientific article published on 01 June 2008

Genetic architecture of circulating lipid levels

artículo científico publicado en 2011

Genetic architecture of open angle glaucoma and related determinants

artículo científico publicado en 2010

Genetic factors influence the clustering of depression among individuals with lower socioeconomic status

artículo científico publicado en 2009

Genetic risk profiles for depression and anxiety in adult and elderly cohorts

artículo científico publicado en 2010

Genetic scoring analysis: a way forward in genome wide association studies?

artículo científico publicado en 2009

Genome-based prediction of breast cancer risk in the general population: a modeling study based on meta-analyses of genetic associations

artículo científico publicado en 2011

Genome-based prediction of common diseases: advances and prospects

artículo científico publicado en 2008

Genome-wide analysis of genetic loci associated with Alzheimer disease

artículo científico publicado en 2010

Genome-wide association analysis of coffee drinking suggests association with CYP1A1/CYP1A2 and NRCAM

artículo científico publicado en 2011

Genome-wide association scan for five major dimensions of personality

artículo científico publicado en 2010

Genome-wide association studies, field synopses, and the development of the knowledge base on genetic variation and human diseases

artículo científico publicado en 2009

Genome-wide association studies, field synopses, and the development of the knowledge base on genetic variation and human diseases

Genome-wide association study identifies novel loci associated with circulating phospho- and sphingolipid concentrations

artículo científico publicado en 2012

Genome-wide association study identifies six new loci influencing pulse pressure and mean arterial pressure

artículo científico publicado en 2011

Genome-wide profiling of blood pressure in adults and children

artículo científico publicado en 2011

HFE gene mutations increase the risk of coronary heart disease in women.

artículo científico publicado en 2010

Health-related quality of life in patients with musculoskeletal complaints in a general acupuncture practice: an observational study

artículo científico publicado en 2010

Heritability of dietary food intake patterns

artículo científico publicado en 2012

How Attitudes Research Contributes to Overoptimistic Expectations of Personal Genome Testing

journal article; published in The American Journal of Bioethics in 2009

How can polygenic inheritance be used in population screening for common diseases?

artículo científico publicado en 2013

IGF-1 CA repeat variant and breast cancer risk in postmenopausal women

artículo científico publicado en 2007

Impact of communicating familial risk of diabetes on illness perceptions and self-reported behavioral outcomes: a randomized controlled trial

artículo científico publicado en 2009

Impact of presymptomatic genetic testing for hereditary ataxia and neuromuscular disorders: where is the evidence?

artículo científico publicado en 2005

Impact of recently diagnosed multiple sclerosis on quality of life, anxiety, depression and distress of patients and partners ⬇️

artículo científico publicado el 1 de diciembre de 2003

Improvement of Risk Prediction by Genomic Profiling: Reclassification Measures Versus the Area Under the Receiver Operating Characteristic Curve

article by Raluca Mihaescu et al published 18 June 2010 in American Journal of Epidemiology

Incremental value of rare genetic variants for the prediction of multifactorial diseases

artículo científico publicado en 2013

Informed Consent in Direct‐to‐Consumer Personal Genome Testing: The Outline of A Model between Specific and Generic Consent ⬇️

artículo científico publicado el 8 de noviembre de 2012

Insulin-resistance and metabolic syndrome are related to executive function in women in a large family-based study

artículo científico publicado en 2010

Interpreting Incremental Value of Markers Added to Risk Prediction Models ⬇️

artículo científico publicado el 8 de agosto de 2012

Is the time right for translation research in genomics?

artículo científico publicado en 2008

It is time to get real when trying to predict educational performance

scientific article published on 13 March 2020

Longevity candidate genes and their association with personality traits in the elderly

artículo científico publicado en 2011

Lowering the P Value Threshold

artículo científico publicado en 2018

Menopause impacts the relation of plasma adiponectin levels with the metabolic syndrome

scientific article published on 26 August 2009

Meta-analyses identify 13 loci associated with age at menopause and highlight DNA repair and immune pathways

artículo científico publicado en 2012

Meta-analysis of genome-wide association for migraine in six population-based European cohorts

artículo científico publicado en 2011

Meta-analysis of genome-wide association studies for personality.

artículo científico publicado en 2010

Migraine is not associated with enhanced atherosclerosis

artículo científico publicado en 2012

Most published research findings are false-but a little replication goes a long way

artículo científico publicado en 2007

Naming and framing in genomic testing

scholarly article by Eline M. Bunnik published in February 2014

No association between the angiotensin-converting enzyme gene and major depression: a case???control study and meta-analysis

article

Novel citation-based search method for scientific literature: a validation study

artículo científico publicado en 2020

Novel citation-based search method for scientific literature: application to meta-analyses

artículo científico publicado en 2015

Novel loci for adiponectin levels and their influence on type 2 diabetes and metabolic traits: a multi-ethnic meta-analysis of 45,891 individuals

artículo científico publicado en 2012

Patients with Barrett's esophagus perceive their risk of developing esophageal adenocarcinoma as low

artículo científico publicado en 2007

Patients with multiple sclerosis prefer early diagnosis

artículo científico publicado en 2004

Pencina et al. respond to "The incremental value of new markers" and "Clinically relevant measures? A note of caution".

artículo científico publicado en 2012

Perception of prognostic risk in patients with multiple sclerosis: the relationship with anxiety, depression, and disease-related distress

artículo científico publicado en 2004

Personal genome testing: test characteristics to clarify the discourse on ethical, legal and societal issues

artículo científico publicado en 2011

Personal utility in genomic testing: is there such a thing?

artículo científico publicado en 2014

Personalizing Breast Cancer Screening Based on Polygenic Risk and Family History

artículo científico publicado en 2020

Perspectives on the use of multiple sclerosis risk genes for prediction

artículo científico publicado en 2011

Plasma β amyloid and the risk of Alzheimer's disease in Down syndrome

artículo científico publicado en 2011

PredictABEL: an R package for the assessment of risk prediction models ⬇️

artículo científico publicado el 24 de marzo de 2011

Predicting Polygenic Obesity Using Genetic Information

artículo científico publicado en 2017

Predicting human height by Victorian and genomic methods

artículo científico publicado en 2009

Predicting type 2 diabetes based on polymorphisms from genome-wide association studies: a population-based study

artículo científico publicado en 2008

Prediction impact curve is a new measure integrating intervention effects in the evaluation of risk models

artículo científico publicado en 2015

Prediction model for knee osteoarthritis incidence, including clinical, genetic and biochemical risk factors

artículo científico publicado en 2013

Prediction of age-related macular degeneration in the general population: the Three Continent AMD Consortium

artículo científico publicado en 2013

Prediction of anxiety and distress following diagnosis of multiple sclerosis: a two-year longitudinal study

artículo científico publicado en 2006

Predictive Value of Multiple Genetic Testing for Age-Related Macular Degeneration

artículo científico publicado en 2007

Predictive ability of direct-to-consumer pharmacogenetic testing: when is lack of evidence really lack of evidence?

artículo científico publicado en 2013

Predictive genetic testing for the identification of high-risk groups: a simulation study on the impact of predictive ability

artículo científico publicado en 2011

Predictive genetic testing for type 2 diabetes

artículo científico publicado en 2006

Predictive or not predictive: understanding the mixed messages from the patient's DNA sequence

artículo científico publicado en 2015

Predictive testing for complex diseases using multiple genes: fact or fiction?

artículo científico publicado en 2006

Pregnancy in multiple sclerosis: clinical and self-report scales

artículo científico publicado en 2011

Prenatal exposure to the 1944-45 Dutch 'hunger winter' and addiction later in life

artículo científico publicado en 2008

Proprietary Algorithms for Polygenic Risk: Protecting Scientific Innovation or Hiding the Lack of It?

artículo científico publicado en 2019

Quality criteria for health checks: development of a European consensus agreement

artículo científico publicado en 2014

ROC curves for clinical prediction models Part 4: Selection of the risk threshold: once chosen, always the same?

artículo científico publicado en 2020

Racial/Ethnic Variation in the Association of Lipid-Related Genetic Variants With Blood Lipids in the US Adult Population

Raw data: access to inaccuracy

artículo científico publicado en 2014

Refining genome-wide linkage intervals using a meta-analysis of genome-wide association studies identifies loci influencing personality dimensions

artículo científico publicado en 2012

Reflection on modern methods: Revisiting the area under the ROC Curve

scientific article published on 22 January 2020

Replication of CD58 and CLEC16A as genome-wide significant risk genes for multiple sclerosis

artículo científico publicado en 2009

Reply to Stephan et al.

artículo científico publicado en 2008

Reply to “Disease risks derived from genetic variants need clinical context”

Research Conducted Using Data Obtained through Online Communities: Ethical Implications of Methodological Limitations

artículo científico publicado en 2012

Response to letter Dr Gail

artículo científico publicado en 2017

Returning pharmacogenetic secondary findings from genome sequencing: let's not put the cart before the horse.

artículo científico publicado en 2015

Revisiting the clinical validity of multiplex genetic testing in complex diseases

artículo científico publicado en 2004

Risk Analysis of Prostate Cancer in PRACTICAL Consortium-Letter

artículo científico publicado en 2016

Risk prediction models: a framework for assessment

artículo científico publicado en 2011

Role of shared genetic and environmental factors in symptoms of depression and body composition

article

Scientific reporting is suboptimal for aspects that characterize genetic risk prediction studies: a review of published articles based on the Genetic RIsk Prediction Studies statement

artículo científico

Self reported stressful life events and exacerbations in multiple sclerosis: prospective study ⬇️

artículo científico publicado el 20 de septiembre de 2003

Shared genetic factors in migraine and depression: evidence from a genetic isolate

artículo científico publicado en 2010

Shared genetic factors in the co-occurrence of symptoms of depression and cardiovascular risk factors

artículo científico publicado en 2009

Simple risk model predicts incidence of atrial fibrillation in a racially and geographically diverse population: the CHARGE-AF consortium

artículo científico publicado en 2013

Small improvement in the area under the receiver operating characteristic curve indicated small changes in predicted risks

artículo científico publicado en 2016

Strengthening the Reporting of Genetic Risk Prediction Studies: The GRIPS Statement

artículo científico publicado en 2011

Strengthening the reporting of Genetic RIsk Prediction Studies (GRIPS): explanation and elaboration

artículo científico publicado en 2011

Strengthening the reporting of Genetic RIsk Prediction Studies: the GRIPS Statement

artículo científico publicado en 2011

Strengthening the reporting of Genetic RIsk Prediction Studies: the GRIPS Statement

artículo científico publicado en 2011

Strengthening the reporting of Genetic Risk Prediction Studies: The GRIPS statement

artículo científico publicado en 2011

Strengthening the reporting of genetic risk prediction studies (GRIPS): explanation and elaboration.

artículo científico publicado en 2011

Strengthening the reporting of genetic risk prediction studies (GRIPS): explanation and elaboration

artículo científico publicado en 2011

Strengthening the reporting of genetic risk prediction studies (GRIPS): explanation and elaboration

Strengthening the reporting of genetic risk prediction studies: The GRIPS Statement

artículo científico publicado en 2011

Strengthening the reporting of genetic risk prediction studies: the GRIPS statement

artículo científico publicado en 2011

Strengthening the reporting of genetic risk prediction studies: the GRIPS statement

Strengthening the reporting of genetic risk prediction studies: the GRIPS statement

Strengthening the reporting of genetic risk prediction studies: the GRIPS statement

artículo científico publicado en 2011

Strengthening the reporting of genetic risk prediction studies: the GRIPS statement.

artículo científico publicado en 2011

Survival in elderly persons with Down syndrome

artículo científico publicado en 2008

The ROC plot: the picture that could be worth a 1000 words

scientific article published on 17 June 2020

The Scientific Foundation for personal genomics: recommendations from a National Institutes of Health-Centers for Disease Control and Prevention multidisciplinary workshop

artículo científico publicado en 2009

The apolipoprotein E gene and its age-specific effects on cognitive function

artículo científico publicado en 2008

The genetic association between personality and major depression or bipolar disorder. A polygenic score analysis using genome-wide association data

artículo científico publicado en 2011

The hidden harm behind the return of results from personal genome services: a need for rigorous and responsible evaluation

artículo científico publicado en 2014

The impact of genotype frequencies on the clinical validity of genomic profiling for predicting common chronic diseases

artículo científico publicado en 2007

The role of disability and depression in cognitive functioning within 2 years after multiple sclerosis diagnosis

artículo científico publicado en 2008

The role of disease characteristics in the ethical debate on personal genome testing

artículo científico publicado en 2012

The sense and nonsense of direct-to-consumer genetic testing for cardiovascular disease

artículo científico publicado en 2011

Three Genome-wide Association Studies and a Linkage Analysis Identify HERC2 as a Human Iris Color Gene

artículo científico publicado en 2008

Three genome-wide association studies and a linkage analysis identify HERC2 as a human iris color gene

artículo científico publicado en 2008

Towards predictive genetic testing of complex diseases

artículo científico publicado en 2006

Translational research in genomics of Alzheimer's disease: a review of current practice and future perspectives

scientific article published on January 2010

Two Authors Reply

Use of genomic profiling to assess risk for cardiovascular disease and identify individualized prevention strategies--a targeted evidence-based review

artículo científico publicado en 2010

Usefulness of genetic polymorphisms and conventional risk factors to predict coronary heart disease in patients with familial hypercholesterolemia

artículo científico publicado en 2009

Useless until proven effective: the clinical utility of preemptive pharmacogenetic testing

artículo científico publicado en 2014

Using family history information to promote healthy lifestyles and prevent diseases; a discussion of the evidence

artículo científico publicado en 2010

Validity of polygenic risk scores: are we measuring what we think we are?

scientific article published on 01 November 2019

Value of EUS in Determining Curative Resectability in Reference to CT and FDG-PET: The Optimal Sequence in Preoperative Staging of Esophageal Cancer?

artículo científico publicado en 2011

Value of genetic profiling for the prediction of coronary heart disease

artículo científico publicado en 2009

Value of the HLA-DRB1 shared epitope for predicting radiographic damage in rheumatoid arthritis depends on the individual patient risk profile

artículo científico publicado en 2006

Variations in predicted risks in personal genome testing for common complex diseases

artículo científico publicado en 2013

Whole genome sequencing--new opportunities for health care practice?

artículo científico publicado el 1 de enero de 2010

Why Realistic Test Scenarios in Translational Genomics Research Remain Hypothetical

artículo científico publicado en 2009

Dominio Público Uruguay está sostenido por:

Acerca de Dominio Público Uruguay

Ayuda