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Lista de obras de Smith Cie

A 40‐base‐pair duplication in the gp91‐phox gene leading to X‐linked chronic granulomatous disease ⬇️

artículo científico publicado el 1 de octubre de 1993

A human homologue of the rat rab geranylgeranyl transferase beta subunit on chromosome 1p22-p31.

artículo científico publicado en 1996

A murine model of acute myeloid leukemia with Evi1 overexpression and autocrine stimulation by an intracellular form of GM-CSF in DA-3 cells.

artículo científico publicado en 2015

A mutation in Bruton's tyrosine kinase as a cause of selective anti-polysaccharide antibody deficiency

scientific article published on 01 July 2001

A peptide nucleic acid-nuclear localization signal fusion that mediates nuclear transport of DNA.

artículo científico publicado en 1999

A synthetic snRNA m3G-CAP enhances nuclear delivery of exogenous proteins and nucleic acids.

artículo científico publicado en 2009

ANKRD54 preferentially selects Bruton's Tyrosine Kinase (BTK) from a Human Src-Homology 3 (SH3) domain library

artículo científico publicado en 2017

Aberrant pattern of anti-carbohydrate antibodies in immunoglobulin class or subclass-deficient donors

artículo científico publicado en 1986

Absence of xid mutation in X-linked agammaglobulinaemia

artículo científico publicado en 1993

Adding functional entities to plasmids.

artículo científico publicado en 2004

Agammaglobulinemia: causative mutations and their implications for novel therapies

artículo científico

Alterations in adenylate cyclase activity due to streptozotocin-induced diabetic cardiomyopathy

artículo científico publicado en 1984

An Academic Centre for Gene Therapy Research with Clinical Grade Manufacturing Capability ⬇️

artículo científico publicado el 1 de diciembre de 1997

An enzyme-linked immunosorbent assay for the determination of the IgA subclass distribution of antigen-specific antibodies

artículo científico publicado en 1988

An intragenic TaqI RFLP at the PAX5 locus

artículo científico publicado en 1994

Analysis of genetic variables in selective human IgG3 deficiency

artículo científico publicado en 1993

Analysis of human IgA subclasses by in situ hybridization and combined in situ hybridization/immunohistochemistry

artículo científico publicado en 1992

Anti-IgA in selective IgA deficiency. In vitro effects and Ig subclass pattern of human anti-IgA

scientific article published on 01 December 1983

Autoantibody formation after bone marrow transplantation. Comparison between acetylcholine receptor antibodies and other autoantibodies and analysis of HLA and Gm markers

scientific article published on 01 January 1989

B Cell Receptor Activation Predominantly Regulates AKT-mTORC1/2 Substrates Functionally Related to RNA Processing

artículo científico publicado en 2016

B cell-deficient muMT mice as an experimental model for Mycoplasma infections in X-linked agammaglobulinemia

scientific article published on 01 August 1997

B-Cell Activating Properties of Polymyxin B ⬇️

artículo científico publicado el 1 de enero de 1978

B-cell chronic lymphocytic leukaemia with aberrant expression of CD8 antigen

artículo científico publicado en 1987

BMX, a novel nonreceptor tyrosine kinase gene of the BTK/ITK/TEC/TXK family located in chromosome Xp22.2

artículo científico publicado en 1994

BTK, the tyrosine kinase affected in X-linked agammaglobulinemia.

artículo científico publicado en 1997

BTKbase, mutation database for X-linked agammaglobulinemia (XLA)

artículo científico publicado en 1997

BTKbase, mutation database for X-linked agammaglobulinemia (XLA)

artículo científico publicado en 1998

BTKbase: XLA-mutation registry

scientific article published on 01 November 1996

BTKbase: the mutation database for X-linked agammaglobulinemia.

artículo científico publicado en 2006

Basic fibroblast growth factor increases retroviral-mediated gene transfer into human hematopoietic peripheral blood progenitor cells.

artículo científico publicado en 1994

Bcl-2 rearrangements with breakpoints in both vcr and mbr in non-Hodgkin's lymphomas and chronic lymphocytic leukaemia

scientific article published on 01 March 1996

Binding and incorporation of lecithin-cholesterol vesicles to lymphocytes: A spin-label study ⬇️

artículo científico publicado el 1 de enero de 1982

Biological activity and biotechnological aspects of locked nucleic acids.

artículo científico

Biological activity and biotechnological aspects of peptide nucleic acid.

artículo científico publicado en 2006

Biological properties of yolk immunoglobulins

scientific article published on 01 January 1995

Bone-marrow grafting induces acetylcholine receptor antibody formation

artículo científico publicado en 1985

Both proline-rich sequences in the TH region of Bruton's tyrosine kinase stabilize intermolecular interactions with the SH3 domain.

artículo científico publicado en 2001

Bruton tyrosine kinase (BTK) in X-linked agammaglobulinemia (XLA).

artículo científico publicado en 2000

Bruton's tyrosine kinase (Btk): function, regulation, and transformation with special emphasis on the PH domain

artículo científico publicado en 2009

Bruton's tyrosine kinase: cell biology, sequence conservation, mutation spectrum, siRNA modifications, and expression profiling.

artículo científico publicado en 2005

Btk29A promotes Wnt4 signaling in the niche to terminate germ cell proliferation in Drosophila

artículo científico publicado en 2014

Building biologically active nucleic acid nanocomplexes

artículo científico publicado en 2008

C2 deficiency, moderately low IgG2 concentrations and lack of the G2m(23) allotype marker in a child with repeated bacterial infections

scientific article published on 01 May 1987

CD40Lbase: a database of CD40L gene mutations causing X-linked hyper-IgM syndrome

article

CTG repeat-targeting oligonucleotides for down-regulating Huntingtin expression.

artículo científico publicado en 2017

Captopril-induced IgA deficiency

scientific article published on 01 February 1991

Cell specific expression of human Bruton's agammaglobulinemia tyrosine kinase gene (Btk) is regulated by Sp1- and Spi-1/PU.1-family members.

artículo científico publicado en 1996

Characterization of Haemophilus influenzae isolates from the respiratory tract of patients with primary antibody deficiencies: evidence for persistent colonizations

scientific article published on 01 January 1995

Characterization of all possible single-nucleotide change caused amino acid substitutions in the kinase domain of Bruton tyrosine kinase.

artículo científico publicado en 2015

Characterization of human lysozyme (muramidase)-releasing cells. Organ distribution and functional properties as analyzed in a protein A plaque assay

artículo científico publicado en 1982

Characterization of self-reactive B cells by polyclonal B-cell activators ⬇️

artículo científico publicado el 1 de enero de 1977

Characterization of the CDR3 region of rearranged alpha heavy chain genes in human fetal liver.

artículo científico publicado en 1998

Chemical Development of Therapeutic Oligonucleotides

artículo científico publicado en 2019

Choosing CCR5 or Rev siRNA in HIV-1

artículo científico publicado en 2003

Chromosomal aberrations in a case of T-cell CLL with concomitant IgA myeloma

scientific article published on 01 October 1983

Circular RNA interference effector molecules (WO10084371).

artículo científico publicado en 2010

Class and subclass-associated specificity differences of anti-gliadin antibodies from mucosa and serum

artículo científico publicado en 1992

Clinical and genetic diagnosis of warts, hypogammaglobulinemia, infections, and myelokathexis syndrome in 10 patients.

artículo científico publicado en 2009

Clinical and molecular analysis of patients with defects in micro heavy chain gene.

artículo científico publicado en 2002

Colocalization of X-linked agammaglobulinemia and X-linked immunodeficiency genes

scientific article published on 01 July 1993

Compensatory signals associated with the activation of human GC 5′ splice sites ⬇️

artículo científico publicado el 23 de mayo de 2011

Con-A-activated T Cells Secrete Factors with Polyclonal B-Cell-activating Properties ⬇️

artículo científico publicado el 1 de enero de 1979

Conformation of full-length Bruton tyrosine kinase (Btk) from synchrotron X-ray solution scattering.

artículo científico publicado en 2003

Cooperative strand invasion of supercoiled plasmid DNA by mixed linear PNA and PNA-peptide chimeras.

artículo científico publicado en 2004

Correlation between deficiency of immunoglobulin subclass G3 and Gm allotype

artículo científico publicado en 1986

Cyclodextrin-peptide conjugates for sequence specific DNA binding

artículo científico publicado en 2015

DNA-based mutation analysis of Bruton's tyrosine kinase gene in patients with X-linked agammaglobulinaemia

artículo científico publicado en 1995

Defective Toll-like receptor 9-mediated cytokine production in B cells from Bruton's tyrosine kinase-deficient mice

article

Delivery, Effect on Cell Viability, and Plasticity of Modified Aptamer Constructs.

artículo científico publicado en 2016

Design and application of bispecific splice-switching oligonucleotides

artículo científico publicado en 2014

Detection of IgA heavy chain constant region genes in IgA deficient donors: evidence against gene deletions

scientific article published on 01 June 1985

Detection of IgD-secreting human lymphocytes at the single cell level by a protein A plaque assay

scientific article published on 01 March 1981

Detection of albumin-secreting hepatocytes at the single cell level by a protein A plaque assay ⬇️

artículo científico publicado el 1 de julio de 1979

Detection of alpha 1 and alpha 2 heavy-chain constant-region genes in common variable hypogammaglobulinaemia patients with undetectable IgA

scientific article published on 01 October 1984

Detection of muramidase (lysozyme)-secreting leucocytes at the single-cell level by a protein A plaque assay

artículo científico publicado en 1980

Development of IgA deficiency after bone marrow transplantation. The influence of acute and chronic graft-versus-host disease

scientific article published on 01 September 1990

Development of IgG2 deficiency in a bone-marrow-transplanted patient. Implication for generation of the anticarbohydrate antibody repertoire in subclass-deficient individuals

artículo científico publicado en 1987

Diagnostics of primary immunodeficiency diseases: a sequencing capture approach

artículo científico publicado en 2014

Diaminopropionic acid lipopeptides: characterization studies of polyplexes aimed at pDNA delivery.

artículo científico publicado en 2012

Different HLA DR-DQ associations in subgroups of idiopathic myasthenia gravis

scientific article published on 01 January 1990

Different Requirements for T Cells Responding to Various Doses of Concanavalin A ⬇️

artículo científico publicado el 1 de enero de 1978

Differential susceptibility to Mycoplasma pulmonis intranasal infection in X-linked immunodeficient (xid), severe combined immunodeficient (scid), and immunocompetent mice

artículo científico publicado en 1997

Digitalis-induced stimulation. Support for a two-receptor model

scientific article published on 01 February 1982

Direct and sequential switching from mu to epsilon in patients with Schistosoma mansoni infection and atopic dermatitis

artículo científico publicado en 1997

Disease models for every field: workshop on the molecular basis of human congenital lymphocyte disorders.

artículo científico publicado en 2002

Disruption of Higher Order DNA Structures in Friedreich's Ataxia (GAA)n Repeats by PNA or LNA Targeting

artículo científico publicado en 2016

Distinct gene expression signature in Btk-defective T1 B-cells

article

Disturbed interaction of p21-rac with mutated p67-phox causes chronic granulomatous disease

artículo científico publicado en 1996

Dual functions of Bruton's tyrosine kinase and Tec kinase during Fcgamma receptor-induced signaling and phagocytosis.

artículo científico publicado en 2008

Dual phosphorylation of Btk by Akt/protein kinase b provides docking for 14-3-3ζ, regulates shuttling, and attenuates both tonic and induced signaling in B cells.

artículo científico publicado en 2013

Duplications and deletions of the human IGHC locus: evolutionary implications

scientific article published on 01 January 1996

Early and prolonged intravenous immunoglobulin replacement therapy in childhood agammaglobulinemia: A retrospective survey of 31 patients

artículo científico publicado en 1999

Early antibody responses in human schistosomiasis

artículo científico publicado en 1990

Enigmas in tumor resistance to kinase inhibitors and calculation of the drug resistance index for cancer (DRIC).

artículo científico publicado en 2016

Enzyme-linked immunosorbent assay for subclass distribution of human IgG and IgA antigen-specific antibodies

artículo científico publicado en 1985

Evaluating coupling procedures for synthesis of lna-Peptide conjugates.

artículo científico publicado en 2007

Evidence for a spontaneous activity and a weak helper function in cord blood lymphocytes

artículo científico publicado en 1982

Evidence for the existence of self-reactive human B lymphocytes ⬇️

artículo científico publicado el 1 de agosto de 1977

Express subcutaneous IgG infusions: decreased time of delivery with maintained safety

scientific article published on 01 September 2002

Expression Analysis in Multiple Muscle Groups and Serum Reveals Complexity in the MicroRNA Transcriptome of the mdx Mouse with Implications for Therapy ⬇️

artículo científico publicado el 14 de agosto de 2012

Expression of Bruton's agammaglobulinemia tyrosine kinase gene, BTK, is selectively down-regulated in T lymphocytes and plasma cells.

artículo científico publicado en 1994

Expression profiling of chicken DT40 lymphoma cells indicates clonal selection of knockout and gene reconstituted cells.

artículo científico publicado en 2008

Extracellular vesicle in vivo biodistribution is determined by cell source, route of administration and targeting.

artículo científico publicado en 2015

False-positive Waaler-Rose test in IgA deficiency

artículo científico publicado en 1985

Family and linkage study of selective IgA deficiency and common variable immunodeficiency.

artículo científico publicado en 1995

Fast and efficient synthesis of Zorro-LNA type 3'-5'-5'-3' oligonucleotide conjugates via parallel in situ stepwise conjugation.

artículo científico publicado en 2016

Fatty acid-spermine conjugates as DNA carriers for nonviral in vivo gene delivery.

artículo científico publicado en 2009

Four Novel Splice-Switch Reporter Cell Lines: Distinct Impact of Oligonucleotide Chemistry and Delivery Vector on Biological Activity.

artículo científico publicado en 2016

Frequencies of interleukin-5 mRNA-producing cells in healthy individuals and in immunoglobulin-deficient patients, measured by in situ hybridization

scientific article published on 01 September 1990

Frequent occurrence of monoclonal gammopathies with an imbalanced light-chain ratio following bone marrow transplantation

artículo científico publicado en 1987

From identification of the BTK kinase to effective management of leukemia.

artículo científico publicado en 2016

Functional Characterization of Lanatoside-C-Responsive Cells ⬇️

artículo científico publicado el 1 de enero de 1978

Functional interaction of caveolin-1 with Bruton's tyrosine kinase and Bmx

artículo científico publicado en 2002

Functional maturity of cord blood B lymphocytes: Staphylococcus aureus Cowan 1 induces IgG secretion in the human neonate

artículo científico publicado en 1983

Functional replacement of Drosophila Btk29A with human Btk in male genital development and survival.

artículo científico publicado en 2005

Functional studies on B cells in human bone marrow: in vitro mitogen stimulation of normal and malignant B cells

artículo científico publicado en 1981

Gap junctions promote the bystander effect of herpes simplex virus thymidine kinase in vivo.

artículo científico publicado en 1997

Gene expression profile of B cells from Xid mice and Btk knockout mice.

artículo científico publicado en 2004

Generation of the antibody repertoire in individuals with multiple immunoglobulin heavy chain constant region gene deletions.

artículo científico publicado en 1987

Genetic and demographic features of X-linked agammaglobulinemia in Eastern and Central Europe: a cohort study.

artículo científico publicado en 2009

Genetic control of effector cell characteristics: con A-induced suppressor cells carry H-2 I region encoded determinants

artículo científico publicado en 1979

Genetic control of lymphocyte suppression. I. Lack of suppression in aged NZB mice is due to a B cell defect ⬇️

artículo científico publicado el 1 de diciembre de 1978

Genetically modified autoactivated cells expressing intracellular forms of GM-CSF as a model for regulated administration of cytokines.

artículo científico publicado en 2005

Genetics of immune disease

scientific article published on 01 March 1992

Gm allotypes in Finnish myasthenia gravis patients

artículo científico publicado en 1984

Gm allotypes in IgA deficiency

scientific article published on 01 June 1985

Gm allotypes in Swedish myasthenia gravis patients

scientific article published on 01 February 1983

HLA and ischemic cerebrovascular disease. A study of patients with stroke before the age of 56

artículo científico publicado en 1983

HLA antigens in selective IgA deficiency: distribution in healthy donors and patients with recurrent respiratory tract infections

artículo científico publicado en 1984

HLA-A, -B, -C and -D antigens in male patients with myasthenia gravis

scientific article published on 01 August 1978

HLA-A, B, C and DR antigens in immunoglobulin A deficiency

scientific article published on 01 January 1983

Herpesvirus serology, aberrant specific immunoglobulin G2 and G3 subclass patterns and Gm allotypes in individuals with low levels of IgG3

artículo científico publicado en 1992

High level of cannabinoid receptor 1, absence of regulator of G protein signalling 13 and differential expression of Cyclin D1 in mantle cell lymphoma

artículo científico publicado en 2003

High levels of interferon gamma in the plasma of children with complete interferon gamma receptor deficiency

artículo científico publicado en 2001

Home treatment of hypogammaglobulinaemia with subcutaneous gammaglobulin by rapid infusion ⬇️

artículo científico publicado el 20 de julio de 1991

Human immunoglobulin germline alpha(IgA) transcripts are expressed in vivo and their level correlates to class switching

scientific article published on 01 January 1993

Human leukocyte antigens group A in couples with unexplained infertility

artículo científico publicado en 1983

Humoral Immunity in scid Mice Reconstituted with Cells from Immunoglobulin-Deficient or Normal Humans ⬇️

artículo científico publicado el 1 de diciembre de 1991

Identification of Btk mutations in 20 unrelated patients with X-Iinked agammaglobulinaemia (XLA)

article

IgA2 allotypes determined by restriction fragment length polymorphism in IgA deficiency. Re-expression of the silent A2m(2) allotype in the children of IgA-deficient patients

artículo científico publicado en 1987

IgG subclass deficiency and chronic fatigue syndrome

scientific article published on 01 April 1988

IgG subclass distribution of antibodies against S. aureus teichoic acid and alpha-toxin in normal and immunodeficient donors

artículo científico publicado en 1984

IgG subclass distribution of antiviral antibodies in common variable immunodeficiency: effect of substitution therapy

scientific article published on 01 December 1988

IgG subclass distribution of autoantibodies against ribonucleoproteins

artículo científico publicado en 1986

IgG subclass distribution of myasthenia gravis thymoma-associated antiskeletal muscle antibodies

scientific article published on 01 August 1984

IgG subclass-associated affinity differences of specific antibodies in humans.

artículo científico publicado en 1988

IgG subclasses in bacterial infections

scientific article published on 01 January 1986

IgG subclasses of specific antibodies in Ixodes ricinus-borne borreliosis

artículo científico publicado en 1987

IgG2 deficiency in a healthy blood donor. Concomitant lack of IgG2, IgA and IgE immunoglobulins and specific anti-carbohydrate antibodies

scientific article published on 01 March 1983

Immunization with HIV-1 envelope T20-encoding DNA vaccines elicits cross-clade neutralizing antibody responses

artículo científico publicado en 2017

Immunodeficiency mutation databases--a new research tool

scientific article published on 01 November 1996

Immunoglobulin levels in saliva in individuals with selective IgA deficiency: compensatory IgM secretion and its correlation with HLA and susceptibility to infections

artículo científico publicado en 1989

Immunoglobulin production in severe combined immunodeficient (SCID) mice reconstituted with human peripheral blood mononuclear cells.

artículo científico publicado en 1992

Immunoglobulin prophylaxis in patients with antibody deficiency syndromes and anti-IgA antibodies

artículo científico publicado en 1987

Immunoglobulin subclass distribution of human anti-carbohydrate antibodies: aberrant pattern in IgA-deficient donors

artículo científico publicado en 1985

Immunoglobulin subclass distribution of specific antibodies in allergic patients. Prediction of the IgE inducing capacity of potential allergens

artículo científico publicado en 1987

Immunoglobulin synthesis in a patient with C4 deficiency: functional immaturity of peripheral blood lymphocytes

scientific article published on 01 August 1985

Immunologic evaluation of T chronic lymphocyte leukaemia cells in a patient with a concomitant IgA2 myeloma

artículo científico publicado en 1984

Immunological unresponsiveness of self-recognizing B lymphocytes to the PBA property of a soluble T cell factor

artículo científico publicado en 1978

In silico tools for signal transduction research.

artículo científico publicado en 2003

In vitro activating properties of polyene antibiotics for murine lymphocytes ⬇️

artículo científico publicado el 1 de agosto de 1977

In vitro induction of human suppressor T cells by a chorionic gonadotropin preparation

artículo científico publicado en 1981

In vitro induction of murine suppressor T-cells by human chorionic gonadotropin

artículo científico publicado en 1980

In vivo expression of human immunoglobulin germ-line mRNA in normal and in immunodeficient individuals

scientific article published on 01 January 1994

Induction of Antibody Synthesis in Human B Lymphocytes by Different Polyclonal B Cell Activators: Evaluation by Direct and Indirect PFC Assays ⬇️

artículo científico publicado el 1 de enero de 1979

Inhibitors of BTK and ITK: state of the new drugs for cancer, autoimmunity and inflammatory diseases.

artículo científico publicado en 2013

Interactions between SH2 and SH3 Domains ⬇️

artículo científico publicado el 14 de enero de 1998

Intercellular delivery of thymidine kinase prodrug activating enzyme by the herpes simplex virus protein, VP22.

artículo científico publicado en 1999

Interleukin 4 induces synthesis of IgE and IgG4 in human B cells

artículo científico publicado en 1989

Intermolecular interactions between the SH3 domain and the proline-rich TH region of Bruton's tyrosine kinase.

artículo científico publicado en 2001

Intranasal inoculation of Mycoplasma pulmonis in mice with severe combined immunodeficiency (SCID) causes a wasting disease with grave arthritis

scientific article published on 01 December 1994

Inversion of chromosome 14 marks human T-cell chronic lymphocytic leukaemia

artículo científico publicado en 1984

Involvement of both HLA and Ig heavy chain haplotypes in human IgA deficiency

artículo científico publicado en 1992

Is cholesterol the receptor for polyene antibiotic-induced B-lymphocyte activation

artículo científico publicado en 1980

Is selective IgA deficiency associated with central HLA genes or alleles of the DR-DQ region?

scientific article published on 01 April 1991

Isolation of cDNA clones mapping around DXS178: a search for human X-linked agammaglobulinaemia gene using yeast artificial chromosomes, cosmids and direct cDNA selection.

artículo científico publicado en 1993

Kinetics of the spontaneously occurring common variable hypogammaglobulinemia: an analysis of two individuals with previously normal immunoglobulin levels

scientific article published on 01 October 1985

LNA effects on DNA binding and conformation: from single strand to duplex and triplex structures

artículo científico publicado en 2017

Lack of IgG in a healthy adult: a rare case of dysgammaglobulinemia with undetectable serum IgG, IgA2, and IgE

scientific article published on 01 January 1984

Lanatoside C, a new polyclonal B-cell activator

artículo científico publicado en 1978

Ligands of the asialoglycoprotein receptor for targeted gene delivery, part 1: Synthesis of and binding studies with biotinylated cluster glycosides containing N-acetylgalactosamine.

artículo científico publicado en 2004

Lipid-based Transfection Reagents Exhibit Cryo-induced Increase in Transfection Efficiency.

artículo científico publicado en 2016

Lipopolysaccharide and lipid A-induced human blood lymphocyte activation as detected by a protein A plaque assay ⬇️

artículo científico publicado el 1 de agosto de 1979

Macrophage-dependence of mitogen responsiveness: macrophages exposed to zymosan enhance the response to polyanions.

artículo científico publicado en 1978

Macrophages are required for the dextran-sulfate induced activation of B lymphocytes ⬇️

artículo científico publicado el 1 de septiembre de 1977

Mantle cell lymphomas with low levels of cyclin D1 long mRNA transcripts are highly proliferative and can be discriminated by elevated cyclin A2 and cyclin B1.

artículo científico publicado en 2005

Micro-minicircle Gene Therapy: Implications of Size on Fermentation, Complexation, Shearing Resistance, and Expression.

scientific article published on 07 January 2014

Missense mutations affecting a conserved cysteine pair in the TH domain of Btk ⬇️

artículo científico publicado el 18 de agosto de 1997

Mitogen-induced switching of immunoglobulin heavy-chain class secretion in chronic B-lymphocytic leukaemia and immunocytoma cell populations

scientific article published on 01 January 1983

Mitogenic activation of human lymphocytes: a protein A plaque assay evaluation of polyclonal B-cell activators

scientific article published on 01 January 1980

Molecular Probing of Disease Susceptibility Genes in Myasthenia Gravis Patients: An Analysis of T-Cell Receptor and HLA Class II Genes Using Restriction Fragment Length Polymorphism

article

Molecular and cellular aspects of X-linked agammaglobulinemia.

artículo científico publicado en 1995

Molecular and serologic analysis of IgG1 deficiency caused by new forms of the constant region of the Ig H chain gene deletions

article

Molecular basis for X-linked immunodeficiencies

scientific article published on 01 January 1997

Molecular basis for human immunodeficiencies.

artículo científico publicado en 1993

Molecular basis of B cell activation: mitogenicity of native and modified digitalis glycosides ⬇️

artículo científico publicado el 1 de marzo de 1978

Molecular basis of B cell activiation--II. Mitogenicity of cardenolide derivatives

scientific article published on 01 April 1980

Molecular cloning, characterization, and chromosomal localization of a human lymphoid tyrosine kinase related to murine Blk.

artículo científico publicado en 1995

Molecular diagnosis of X-linked agammaglobulinaemia

artículo científico publicado en 1993

Monitoring of mite Dermatophagoides farinae allergen-specific IgG and IgG subclass distribution in patients on immunotherapy

artículo científico publicado en 1992

Mutation Screening of the BTK Gene in 56 Families With X-Linked Agammaglobulinemia (XLA): 47 Unique Mutations Without Correlation to Clinical Course ⬇️

artículo científico publicado el 1 de febrero de 1998

Mutation pattern in the Bruton's tyrosine kinase gene in 26 unrelated patients with X-linked agammaglobulinemia

artículo científico publicado en 1997

Mutations of the humanBTK gene coding for bruton tyrosine kinase in X-linked agammaglobulinemia

artículo científico publicado en 1999

Myasthenia gravis after bone-marrow transplantation. Evidence for a donor origin

scientific article published on 01 December 1983

Myasthenia gravis: studies on HL-A antigens and lymphocyte subpopulations in patients with myasthenia gravis ⬇️

artículo científico publicado el 1 de agosto de 1975

Nanotechnology approaches for gene transfer.

scientific article published on 02 June 2009

Neuromuscular safety margin: genetical, immunological and electrophysiological determinants in relatives of myasthenic patients: a preliminary report

scientific article published on 01 January 1981

Next-generation bis-locked nucleic acids with stacking linker and 2'-glycylamino-LNA show enhanced DNA invasion into supercoiled duplexes

artículo científico publicado en 2016

No Significant Correlation of HLA-B8 and Amount of Antibodies Directed to Acetylcholine Receptor Protein in Patients with Myasthenia Gravis ⬇️

artículo científico publicado el 1 de noviembre de 1978

No influence of conversions affecting allotype expression on the IgG subclass restriction of specific antibodies

artículo científico publicado en 1989

No role of HLA in mate selection

scientific article published on 01 January 1983

No significant association between HLA and Bell's palsy

scientific article published on 01 November 1978

Non-viral nanovectors for gene delivery: factors that govern successful therapeutics.

scientific article published on June 2010

Novel endosomolytic compounds enable highly potent delivery of antisense oligonucleotides

artículo científico publicado en 2022

Nuclease resistant oligonucleotides with cell penetrating properties.

artículo científico publicado en 2015

Oligonucleotide Binding to Non-B-DNA in

artículo científico publicado en 2019

Oligonucleotide Therapies: The Past and the Present

artículo científico publicado en 2015

Oligonucleotides Targeting DNA Repeats Downregulate <i>Huntingtin</i> Gene Expression in Huntington's Patient-Derived Neural Model System

scientific article published on 13 September 2021

Oligonucleotide⁻Palladacycle Conjugates as Splice-Correcting Agents

artículo científico publicado en 2019

Ontogeny of IgG2 antibodies against S. aureus teichoic acid in normal and immunodeficient children

scientific article published on 01 January 1985

Ontogeny of immunoglobulins in bone marrow-transplanted individuals. An analysis of serum and salivary levels

scientific article published on 01 November 1988

Optimizing anti-gene oligonucleotide 'Zorro-LNA' for improved strand invasion into duplex DNA.

artículo científico publicado en 2010

Oral and intestinal microflora in individuals with different immunoglobulin deficiencies

artículo científico publicado en 1990

Oral conditions in individuals with selective immunoglobulin A deficiency and common variable immunodeficiency

artículo científico publicado en 1992

Oral immunoglobulin treatment in Campylobacter jejuni enteritis

scientific article published on 01 April 1993

Peptide nanoparticle delivery of charge-neutral splice-switching morpholino oligonucleotides.

artículo científico publicado en 2015

Phosphatidylinositol-3-kinase-dependent phosphorylation of SLP-76 by the lymphoma-associated ITK-SYK fusion-protein.

artículo científico publicado en 2009

Phosphorylation of Bruton's tyrosine kinase by c-Abl.

artículo científico publicado en 2002

Phylogeny of Tec family kinases identification of a premetazoan origin of Btk, Bmx, Itk, Tec, Txk, and the Btk regulator SH3BP5.

artículo científico publicado en 2008

Placental transfer of intravenous immunoglobulin

scientific article published on 01 March 1986

Plasma anti-pneumococcal antibody activity of the IgG class and subclasses in otitis prone children

artículo científico publicado en 1984

Pneumococcal antibodies of different immunoglobulin subclasses in normal and IgG subclass deficient individuals of various ages

scientific article published on 01 January 1986

Pokeweed mitogen induced differentiation of human B cells: evaluation by a protein A haemolytic plaque assay ⬇️

artículo científico publicado el 1 de septiembre de 1979

Polyclonal B-cell activators induce immunological response to autologous serum proteins

artículo científico publicado en 1977

Polyclonal human T lymphocyte activation results in the secondary functional activation of the human B lymphocyte

scientific article published on 01 January 1981

Polymyxins as inhibitors of polyclonal B-cell activators in murine lymphocyte cultures ⬇️

artículo científico publicado el 1 de mayo de 1977

Positional cloning and the molecular basis of immunodeficiency.

artículo científico publicado en 1995

Predisposition to childhood acute lymphoblastic leukemia caused by a constitutional translocation disrupting ETV6

artículo científico publicado en 2019

Preventive effect of IgG from EBV-seropositive donors on the development of human lympho-proliferative disease in SCID mice

artículo científico publicado en 1997

Primary deficiencies of B and T lymphocytes: molecular basis and clinical aspects

artículo científico publicado en 1989

Proteasome inhibitors block HIV-1 replication by affecting both cellular and viral targets.

artículo científico publicado en 2009

Proteasome-dependent autoregulation of Bruton tyrosine kinase (Btk) promoter via NF-kappaB.

artículo científico publicado en 2008

Protein kinase B (AKT) regulates SYK activity and shuttling through 14-3-3 and importin 7.

artículo científico publicado en 2016

Proximal promoter of the murine syndecan-1 gene is not sufficient for the developmental pattern of syndecan expression in B lineage cells.

artículo científico publicado en 2001

Quantitative and qualitative analysis of human IgG subclass specific mRNA using solution hybridization

scientific article published on 01 November 1991

RNA therapeutics inactivate PCSK9 by inducing a unique intracellular retention form.

artículo científico publicado en 2015

Rabbit anti-human beta 2 microglobulin antibodies: a T-cell mitogen

scientific article published on 01 December 1985

Rational design and purification of human Bruton's tyrosine kinase SH3-SH2 protein for structure-function studies.

artículo científico publicado en 2000

Reduction in serum levels of antimitochondrial (M2) antibodies following immunoglobulin therapy in severe combined immunodeficient (SCID) mice reconstituted with lymphocytes from patients with primary biliary cirrhosis (PBC)

scientific article published on 01 August 1996

Regulation of Bruton tyrosine kinase by the peptidylprolyl isomerase Pin1.

artículo científico publicado en 2006

Regulation of C gamma 3 expression. Role of switch in the allotype-associated variation of human serum IgG3 levels

artículo científico publicado en 1992

Regulation of Lymphocyte Activation by Serum Factors

artículo científico publicado el 1 de enero de 1979

Regulation of nucleocytoplasmic shuttling of Bruton's tyrosine kinase (Btk) through a novel SH3-dependent interaction with ankyrin repeat domain 54 (ANKRD54).

artículo científico publicado en 2012

Regulation of thymus-independent responses by concanavalin A-activated spleen cells

artículo científico publicado en 1979

Repeatable, Inducible Micro-RNA-Based Technology Tightly Controls Liver Transgene Expression.

artículo científico publicado en 2014

Restriction fragment length polymorphism analysis of T-cell receptor genes in inflammatory bowel disease.

artículo científico publicado en 1989

Retroviral-mediated gene transfer into human bone marrow stromal cells: studies of efficiency and in vivo survival in SCID mice.

artículo científico publicado en 1995

Retroviral-mediated gene transfer into human myeloma cells

scientific article published on 01 October 1994

Retroviral-mediated gene transfer of CD34-enriched bone marrow and peripheral blood cells during autologous stem cell transplantation for multiple myeloma

artículo científico publicado en 1994

Reversible inhibition of lymphocyte proliferation by rubidium ions

artículo científico publicado en 1979

Role of Suppressor T Cells in Autoimmune Responses Induced by Polyclonal B Cell Activators ⬇️

artículo científico publicado el 1 de enero de 1978

Role of penicillamine for the induction of myasthenia gravis.

artículo científico publicado en 1983

Role of virus for the induction of myasthenia gravis.

artículo científico publicado en 1978

SSCP/SacI polymorphism in the PAX5 gene

artículo científico publicado en 1994

Safety and efficacy of DNA vaccines: plasmids vs. minicircles

artículo científico

Safety of rapid subcutaneous gammaglobulin infusions in patients with primary antibody deficiency

scientific article published on 01 January 1993

Salivary and serum immunoglobulins in recipients of transplanted allogeneic and autologous bone marrow

scientific article published on 01 August 1994

Septic osteomyelitis and polyarthritis with ureaplasma in hypogammaglobulinemia

artículo científico publicado en 1989

Sequence-selective DNA recognition and enhanced cellular up-take by peptide-steroid conjugates.

artículo científico publicado en 2015

Sequence-specific inhibition of RNA polymerase III-dependent transcription using Zorro locked nucleic acid (LNA).

artículo científico

Sera from lipopolysaccharide (LPS)-injected mice exhibit complement-dependent cytotoxicity against syngeneic and autologous spleen cells

artículo científico publicado en 1977

Sex-dependent induction of human suppressor T cells by chorionic gonadotropin

scientific article published on 01 August 1982

Signaling of the ITK (interleukin 2-inducible T cell kinase)-SYK (spleen tyrosine kinase) fusion kinase is dependent on adapter SLP-76 and on the adapter function of the kinases SYK and ZAP70.

artículo científico publicado en 2013

Signalling of Bruton's tyrosine kinase, Btk.

artículo científico publicado en 1999

Silencing of Bruton's tyrosine kinase (Btk) using short interfering RNA duplexes (siRNA)

scientific journal article

Single-stranded DNA oligonucleotides inhibit TLR3-mediated responses in human monocyte-derived dendritic cells and in vivo in cynomolgus macaques

article

Six X-Linked Agammaglobulinemia-Causing Missense Mutations in the Src Homology 2 Domain of Bruton's Tyrosine Kinase: Phosphotyrosine-Binding and Circular Dichroism Analysis

article

Sodium polyanethole sulfonate: a new macrophage-dependent polymyxin-inhibitable, polyclonal B cell activator ⬇️

artículo científico publicado el 1 de septiembre de 1978

Solid formulation of cell-penetrating peptide nanocomplexes with siRNA and their stability in simulated gastric conditions.

artículo científico publicado en 2012

Solution structure of the SH3 domain from Bruton's tyrosine kinase

artículo científico publicado en 1998

Species restriction of the mitogenicity induced by lanatoside C. Lymphocyte activation by digitalis glycosides is confined to cells from digitalis resistant species ⬇️

artículo científico publicado el 1 de junio de 1979

Specific chromosome markers involved with chronic T lymphocyte tumors

artículo científico publicado en 1986

Specific dsDNA recognition by a mimic of the DNA binding domain of the c-Myc/Max transcription factor.

artículo científico publicado en 2017

Splice-correcting oligonucleotides restore BTK function in X-linked agammaglobulinemia model

artículo científico publicado en 2014

Splice-correction strategies for treatment of X-linked agammaglobulinemia.

artículo científico publicado en 2015

Strategies for codon usage in human VH families

artículo científico publicado en 1988

Structural aspects of signal transduction in B-cells.

artículo científico publicado en 1996

Structural basis for X-linked agammaglobulinemia (XLA): mutations at interacting Btk residues R562, W563, and A582

scientific article published on 01 September 1995

Structural basis for pleckstrin homology domain mutations in X-linked agammaglobulinemia

artículo científico publicado en 1995

Structural basis of SH2 domain mutations in X-linked agammaglobulinemia

scientific article published on 01 December 1994

Structure of TGF-β1-induced human immunoglobulin Cα1 and Cα2 germ-line transcripts ⬇️

artículo científico publicado el 1 de noviembre de 1991

Studies of the molecular basis of IgA production, subclass regulation and class-switch recombination in IgA nephropathy patients

artículo científico publicado en 1996

Subclass distribution and IgE responses after treatment in human schistosomiasis

scientific article published on 01 September 1988

Subclass distribution of antigen-specific IgA antibodies in normal donors and individuals with homozygous C alpha 1 or C alpha 2 gene deletions

artículo científico publicado en 1990

Subclass distribution of human anti-Staphylococcus aureus alpha toxin antibodies: suggestion of an IgG1, IgA1, IgG4 switch pattern

artículo científico publicado en 1984

Subclass restriction pattern of antigen-specific antibodies in donors with defective expression of IgG or IgA subclass heavy chain constant region genes

scientific article published on 01 December 1987

Substitution scanning identifies a novel, catalytically active ibrutinib-resistant BTK cysteine 481 to threonine (C481T) variant.

artículo científico publicado en 2016

Sugar and Polymer Excipients Enhance Uptake and Splice-Switching Activity of Peptide-Dendrimer/Lipid/Oligonucleotide Formulations

scientific article published on 09 December 2019

Suicide gene therapy for plasma cell tumors.

artículo científico publicado en 1996

Suicide genes and bystander killing: local and distant effects.

artículo científico publicado en 1997

Synergistic activation of the human Btk promoter by transcription factors Sp1/3 and PU.1.

artículo científico publicado en 1999

Synthesis and evaluation of stability of m3G-CAP analogues in serum-supplemented medium and cytosolic extract.

artículo científico publicado en 2013

Systemic immunization against IgA in immunoglobulin deficiency

scientific article published on 01 November 1993

T-cell receptor beta gene rearrangements in leukaemic B-cells from patients with chronic lymphocytic leukaemia: association with chromosome 6 deletions

scientific article published on 01 February 1994

TEC family kinases in health and disease – loss‐of‐function of BTK and ITK and the gain‐of‐function fusions ITK–SYK and BTK–SYK ⬇️

artículo científico publicado el 18 de mayo de 2011

TGF-beta 1 induces germ-line transcripts of both IgA subclasses in human B lymphocytes.

artículo científico publicado en 1991

Targeted Oligonucleotides for Treating Neurodegenerative Tandem Repeat Diseases

artículo científico publicado en 2019

Targets for Ibrutinib Beyond B Cell Malignancies

artículo científico publicado en 2015

Tec family kinases.

artículo científico publicado en 2011

Tec homology (TH) adjacent to the PH domain.

artículo científico publicado en 1994

Temperature-assisted cyclic hybridization (TACH): an improved method for supercoiled DNA hybridization.

artículo científico publicado en 2010

The Role of Adherent Cells in B and T Lymphocyte Activation ⬇️

artículo científico publicado el 1 de enero de 1978

The SCID mouse as a model for autoimmunity.

artículo científico publicado en 1993

The ability of locked nucleic acid oligonucleotides to pre-structure the double helix: A molecular simulation and binding study

artículo científico publicado en 2019

The cellular phenotype conditions Btk for cell survival or apoptosis signaling.

artículo científico publicado en 2000

The gene involved in X-linked agammaglobulinaemia is a member of the Src family of protein-tyrosine kinases. 1993.

artículo científico publicado en 2012

The immunodepressive effect of human glucoproteins and their possible role in the nonrejection process during pregnancy

artículo científico publicado en 1979

The influence of gene deletions and duplications within the IGHC locus on serum immunoglobulin subclass levels.

artículo científico publicado en 1995

The influence of gene duplications in the human immunoglobulin heavy chain constant locus on serum levels of immunoglobulin

scientific article published on 01 January 1993

The life situations of patients with primary antibody deficiency untreated or treated with subcutaneous gammaglobulin infusions.

artículo científico publicado en 1993

The protein-A plaque assay: a new system for the detection of cells secreting a given idiotype

scientific article published on 01 January 1980

The sequential appearance of IgG subclasses and IgE during the course of Trichinella spiralis infection

artículo científico publicado en 1988

The subcellular Sox11 distribution pattern identifies subsets of mantle cell lymphoma: correlation to overall survival

scientific article published on 20 August 2008

The transcriptional regulator PLZF induces the development of CD44 high memory phenotype T cells

artículo científico publicado en 2008

The use of human antigen-specific monoclonal antibodies in an enzyme-linked immunosorbent assay for the determination of anti-HBsAg antibody subclasses.

artículo científico publicado en 1987

Therapeutic Oligonucleotides: State of the Art

artículo científico publicado en 2018

Thermal unfolding of small proteins with SH3 domain folding pattern.

artículo científico publicado en 1998

Transcription of unrearranged Ig H chain genes in human B cell malignancies. Biased expression of genes encoded within the first duplication unit of the Ig H chain locus.

artículo científico publicado en 1992

Transcription, translation and secretion of both IgA subclasses in polyclonally activated human lymphocytes.

artículo científico publicado en 1990

Transcriptional signatures of Itk-deficient CD3+, CD4+ and CD8+ T-cells

artículo científico publicado en 2009

Transfer by BMT of IgG2 deficiency involving an immunoglobulin heavy chain constant region deletion and a silent IgG2 gene

artículo científico publicado en 1993

Transfer of IgA deficiency to a bone-marrow-grafted patient with aplastic anaemia

artículo científico publicado en 1985

Translocation-generated ITK-FER and ITK-SYK fusions induce STAT3 phosphorylation and CD69 expression

artículo científico publicado en 2018

Ultrafiltration with size-exclusion liquid chromatography for high yield isolation of extracellular vesicles preserving intact biophysical and functional properties

artículo científico publicado en 2015

Variations in the human phospholipase Cγ2 gene in patients with B-cell defects of unknown etiology ⬇️

artículo científico publicado el 1 de septiembre de 2001

Viral etiology in myasthenia gravis? Analysis of thymic tissue

artículo científico publicado en 1986

Virus-specific antibody activity of different subclasses of immunoglobulins G and A in cytomegalovirus infections ⬇️

artículo científico publicado el 1 de octubre de 1983

When does an autoimmune disease start?

artículo científico publicado en 1983

Wnt/β-Catenin Stimulation and Laminins Support Cardiovascular Cell Progenitor Expansion from Human Fetal Cardiac Mesenchymal Stromal Cells

artículo científico publicado en 2016

Zorro locked nucleic acid induces sequence-specific gene silencing.

artículo científico

[Gene therapy is probably going to fulfil expectations. Not yet a risk-free therapeutic method]

artículo científico publicado en 2001

[Gene therapy. Expectations and realization]

artículo científico publicado en 1996

beta 2-Microglobulin secretion from lymphoid cells: a study at the cellular level

scientific article published on 01 January 1985

mRNA and microRNA transcriptomics analyses in a murine model of dystrophin loss and therapeutic restoration.

artículo científico publicado en 2015

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