Lista de obras - Joseph Zabner - Dominio Público Uruguay

A common mutation in paraoxonase-2 results in impaired lactonase activity.

scientific article published on December 2009

A low rate of cell proliferation and reduced DNA uptake limit cationic lipid-mediated gene transfer to primary cultures of ciliated human airway epithelia ⬇️

artículo científico publicado el 1 de noviembre de 1997

A mouse model for the delta F508 allele of cystic fibrosis.

artículo científico publicado en 1995

A novel host defense system of airways is defective in cystic fibrosis

artículo científico publicado en 2007

A role for the PDZ-binding domain of the coxsackie B virus and adenovirus receptor (CAR) in cell adhesion and growth

artículo científico publicado en 2004

A shortened adeno-associated virus expression cassette for CFTR gene transfer to cystic fibrosis airway epithelia.

artículo científico publicado en 2005

Absence of amiloride-sensitive sodium absorption in the airway of an infant with pseudohypoaldosteronism

scientific article published on 01 December 1999

Abundant DNase I-Sensitive Bacterial DNA in Healthy Porcine Lungs and Its Implications for the Lung Microbiome ⬇️

artículo científico publicado el 19 de julio de 2013

Adenoviral gene transfer corrects the ion transport defect in the sinus epithelia of a porcine CF model

artículo científico publicado en 2013

Adenoviral-mediated gene transfer to fetal pulmonary epithelia in vitro and in vivo.

artículo científico publicado en 1995

Adenovirus 5-fiber 35 chimeric vector mediates efficient apical correction of the cystic fibrosis transmembrane conductance regulator defect in cystic fibrosis primary airway epithelia.

artículo científico publicado en 2010

Adenovirus fiber disrupts CAR-mediated intercellular adhesion allowing virus escape

artículo científico publicado en 2002

Adenovirus-mediated gene therapy for head and neck squamous cell carcinomas.

artículo científico publicado en 1996

Adenovirus-mediated gene transfer for cystic fibrosis: Part A. Safety of dose and repeat administration in the nasal epithelium. Part B. Clinical efficacy in the maxillary sinus

scientific article published on 01 February 1995

Adenovirus-mediated gene transfer transiently corrects the chloride transport defect in nasal epithelia of patients with cystic fibrosis.

artículo científico publicado en 1993

Aggregates of mutant CFTR fragments in airway epithelial cells of CF lungs: new pathologic observations

artículo científico publicado en 2014

Airway acidification initiates host defense abnormalities in cystic fibrosis mice.

artículo científico publicado en 2016

Airway surface liquid from smokers promotes bacterial growth and biofilm formation via iron-lactoferrin imbalance.

artículo científico publicado en 2018

Alveolar macrophages inhibit retrovirus-mediated gene transfer to airway epithelia.

artículo científico publicado en 1997

Apical localization of the coxsackie-adenovirus receptor by glycosyl-phosphatidylinositol modification is sufficient for adenovirus-mediated gene transfer through the apical surface of human airway epithelia

artículo científico publicado en 2001

Augmentation of lung liquid clearance via adenovirus-mediated transfer of a Na,K-ATPase beta1 subunit gene ⬇️

artículo científico publicado el 1 de octubre de 1998

Bronchoalveolar fluid is not a major hindrance to virus-mediated gene therapy in cystic fibrosis.

artículo científico publicado en 2002

Bronchoscopic assessment of airway retention time of aerosolized xylitol.

artículo científico publicado en 2006

CFTR DeltaF508 mutation has minimal effect on the gene expression profile of differentiated human airway epithelia

artículo científico publicado en 2005

CFTR gene transfer with AAV improves early cystic fibrosis pig phenotypes

artículo científico publicado en 2016

CFTR is required for maximal transepithelial liquid transport in pig alveolar epithelia

artículo científico publicado en 2012

Canine adenovirus vectors for lung-directed gene transfer: efficacy, immune response, and duration of transgene expression using helper-dependent vectors.

artículo científico publicado en 2006

Cationic lipid mediated gene transfer of CFTR: safety of a single administration to the nasal epithelia

artículo científico publicado en 1999

Cationic lipid-mediated transfer of the hIL-10 gene prolongs survival of allogeneic hepatocytes in Nagase analbuminemic rats

scientific article published on 01 December 1996

Cellular and Molecular Barriers to Gene Transfer by a Cationic Lipid ⬇️

artículo científico publicado el 11 de agosto de 1995

Cellular localization and activity of Ad-delivered GFP-CFTR in airway epithelial and tracheal cells.

artículo científico publicado en 2007

Characterization of fusion genes and the significantly expressed fusion isoforms in breast cancer by hybrid sequencing.

artículo científico publicado en 2015

Chest wall strapping increases expiratory airflow and detectable airway segments in computer tomographic scans of normal and obstructed lungs.

artículo científico publicado en 2018

Comparison of DNA-lipid complexes and DNA alone for gene transfer to cystic fibrosis airway epithelia in vivo ⬇️

artículo científico publicado el 15 de septiembre de 1997

Complexes of adenovirus with polycationic polymers and cationic lipids increase the efficiency of gene transfer in vitro and in vivo.

artículo científico publicado en 1997

Concentration of the antibacterial precursor thiocyanate in cystic fibrosis airway secretions

artículo científico publicado en 2011

Correction of cAMP-stimulated fluid secretion in cystic fibrosis airway epithelia: efficiency of adenovirus-mediated gene transfer in vitro

article

Cystic Fibrosis Transmembrane Conductance Regulator Potentiation as a Therapeutic Strategy for Pulmonary Edema: A Proof-of-Concept Study in Pigs.

artículo científico publicado en 2017

Cystic fibrosis pigs develop lung disease and exhibit defective bacterial eradication at birth

artículo científico publicado en 2010

DEVELOPMENT OF A POLARIZED PANCREATIC DUCTULAR CELL EPITHELIA FOR PHYSIOLOGICAL STUDIES.

artículo científico publicado en 2018

Differential expression of sheep beta-defensin-1 and -2 and interleukin 8 during acute Mannheimia haemolytica pneumonia.

artículo científico publicado en 2004

Differentiation of human airway epithelia is dependent on erbB2

scientific article published on 17 February 2006

Directed evolution of adeno-associated virus to an infectious respiratory virus

artículo científico publicado en 2009

Disruption of the CFTR gene produces a model of cystic fibrosis in newborn pigs

artículo científico publicado en 2008

Do cell junction protein mutations cause an airway phenotype in mice or humans?

artículo científico publicado en 2011

Drosophila are protected from Pseudomonas aeruginosa lethality by transgenic expression of paraoxonase-1.

artículo científico publicado en 2008

Dual therapeutic utility of proteasome modulating agents for pharmaco-gene therapy of the cystic fibrosis airway.

artículo científico publicado en 2004

Effect of vitamin D3 on the antimicrobial activity of human airway surface liquid: preliminary results of a randomised placebo-controlled double-blind trial.

artículo científico publicado en 2017

Effects of Coal Fly Ash Particulate Matter on the Antimicrobial Activity of Airway Surface Liquid

artículo científico publicado en 2017

Electrolyte transport properties in distal small airways from cystic fibrosis pigs with implications for host defense

artículo científico publicado en 2016

Enamel pathology resulting from loss of function in the cystic fibrosis transmembrane conductance regulator in a porcine animal model

artículo científico publicado en 2011

Enhanced sialic acid-dependent endocytosis explains the increased efficiency of infection of airway epithelia by a novel adeno-associated virus

artículo científico publicado en 2011

Evaluation of in vivo total and regional air content and distribution in primate lungs with high-resolution CT.

artículo científico publicado en 1997

Expression of the complement anaphylatoxin C3a and C5a receptors on bronchial epithelial and smooth muscle cells in models of sepsis and asthma

artículo científico publicado en 2001

Feline immunodeficiency virus vectors persistently transduce nondividing airway epithelia and correct the cystic fibrosis defect

artículo científico publicado en 1999

Foxj1 is required for apical localization of ezrin in airway epithelial cells

scientific journal article

Functional effects of coxsackievirus and adenovirus receptor glycosylation on homophilic adhesion and adenoviral infection.

artículo científico publicado en 2007

Gene transfer of CFTR to airway epithelia: low levels of expression are sufficient to correct Cl- transport and overexpression can generate basolateral CFTR.

artículo científico publicado en 2005

Gene transfer to airway epithelia using feline immunodeficiency virus-based lentivirus vectors

artículo científico publicado en 2002

Glucose depletion in the airway surface liquid is essential for sterility of the airways

artículo científico publicado en 2011

Higher BMI is associated with higher expiratory airflow normalised for lung volume (FEF25-75/FVC) in COPD

artículo científico publicado en 2017

Histamine alters E-cadherin cell adhesion to increase human airway epithelial permeability.

artículo científico publicado en 2003

Hoechst increases adeno-associated virus-mediated transgene expression in airway epithelia by inducing the cytomegalovirus promoter

artículo científico publicado en 2012

Human cystic fibrosis airway epithelia have reduced Cl- conductance but not increased Na+ conductance.

artículo científico publicado en 2011

Impaired mucus detachment disrupts mucociliary transport in a piglet model of cystic fibrosis.

artículo científico publicado en 2014

In Situ Quantification of Glucose Concentration in Airway Surface Liquid With Functionalized ZnO Nanorod-Coated Microelectrodes ⬇️

artículo científico publicado el 12 de agosto de 2011

Inactivation of a Pseudomonas aeruginosa quorum-sensing signal by human airway epithelia.

scholarly article

Incorporation of adenovirus in calcium phosphate precipitates enhances gene transfer to airway epithelia in vitro and in vivo ⬇️

artículo científico publicado el 1 de julio de 1998

Increasing epithelial junction permeability enhances gene transfer to airway epithelia In vivo.

artículo científico publicado en 2000

Inflammatory response in airway epithelial cells isolated from patients with cystic fibrosis.

artículo científico publicado en 2002

Integrin α6β4 identifies human distal lung epithelial progenitor cells with potential as a cell-based therapy for cystic fibrosis lung disease

artículo científico publicado en 2013

Interdependency of beta-adrenergic receptors and CFTR in regulation of alveolar active Na+ transport.

artículo científico publicado en 2005

Interleukin-9 induces goblet cell hyperplasia during repair of human airway epithelia

artículo científico publicado en 2003

Intestinal CFTR expression alleviates meconium ileus in cystic fibrosis pigs

artículo científico publicado en 2013

Iron oxide nanoparticles induce Pseudomonas aeruginosa growth, induce biofilm formation, and inhibit antimicrobial peptide function

artículo científico publicado en 2014

Isoform-specific regulation and localization of the coxsackie and adenovirus receptor in human airway epithelia

artículo científico publicado en 2010

Ivacaftor-induced sweat chloride reductions correlate with increases in airway surface liquid pH in cystic fibrosis

artículo científico publicado en 2018

Keratinocyte growth factor induced epithelial proliferation facilitates retroviral–mediated gene transfer to distal lung epithelia in vivo

article

Lack of high affinity fiber receptor activity explains the resistance of ciliated airway epithelia to adenovirus infection

artículo científico publicado en 1997

Large-scale gene discovery in human airway epithelia reveals novel transcripts

artículo científico publicado en 2004

Loss of CFTR chloride channels alters salt absorption by cystic fibrosis airway epithelia in vitro.

artículo científico publicado en 1998

Loss of carbonic anhydrase XII function in individuals with elevated sweat chloride concentration and pulmonary airway disease

artículo científico publicado en 2016

Loss of cystic fibrosis transmembrane conductance regulator function produces abnormalities in tracheal development in neonatal pigs and young children

artículo científico publicado en 2010

Lysozyme secretion by submucosal glands protects the airway from bacterial infection.

artículo científico publicado en 2005

MMP9 modulates tight junction integrity and cell viability in human airway epithelia

artículo científico publicado en 2009

Medical reversal of chronic sinusitis in a cystic fibrosis patient with ivacaftor

artículo científico publicado en 2014

Mitochondrial-targeted antioxidant therapy decreases transforming growth factor-β-mediated collagen production in a murine asthma model

artículo científico publicado en 2015

Neonates with cystic fibrosis have a reduced nasal liquid pH; a small pilot study

artículo científico publicado en 2014

Newborn Cystic Fibrosis Pigs Have a Blunted Early Response to an Inflammatory Stimulus

artículo científico publicado en 2016

Nominal carbonic anhydrase activity minimizes airway-surface liquid pH changes during breathing.

artículo científico publicado en 2018

Patterns and density of early tracheal colonization in intensive care unit patients.

artículo científico publicado en 2009

Pigs and humans with cystic fibrosis have reduced insulin-like growth factor 1 (IGF1) levels at birth

artículo científico publicado en 2010

Postnatal airway growth in cystic fibrosis piglets

artículo científico publicado en 2017

Practical reconstruction method for bioluminescence tomography

artículo científico publicado en 2005

Precision Genomic Medicine in Cystic Fibrosis

artículo científico publicado en 2015

Protein Kinase Cζ Inhibitor Promotes Resolution of Bleomycin-Induced Acute Lung Injury.

artículo científico publicado en 2016

Protein composition of bronchoalveolar lavage fluid and airway surface liquid from newborn pigs

artículo científico publicado en 2013

Recombinant adeno-associated virus type 2, 4, and 5 vectors: transduction of variant cell types and regions in the mammalian central nervous system.

artículo científico publicado en 2000

Reduced airway surface pH impairs bacterial killing in the porcine cystic fibrosis lung

artículo científico publicado en 2012

Repurposing tromethamine as inhaled therapy to treat CF airway disease.

artículo científico publicado en 2016

Requirements for ion and solute transport, and pH regulation during enamel maturation.

artículo científico publicado en 2012

Role of PON in anoxia-reoxygenation injury: a Drosophila melanogaster transgenic model

artículo científico publicado en 2014

Safety and efficacy of repetitive adenovirus-mediated transfer of CFTR cDNA to airway epithelia of primates and cotton rats.

artículo científico publicado en 1994

Safety assessment of inhaled xylitol in mice and healthy volunteers

artículo científico publicado en 2004

Safety assessment of inhaled xylitol in subjects with cystic fibrosis.

artículo científico publicado en 2006

Safety assessment of nebulized xylitol in beagle dogs

artículo científico publicado en 2012

Secreted and transmembrane mucins inhibit gene transfer with AAV4 more efficiently than AAV5.

artículo científico publicado en 2002

Segregation of receptor and ligand regulates activation of epithelial growth factor receptor

artículo científico publicado en 2003

Sinus hypoplasia precedes sinus infection in a porcine model of cystic fibrosis

artículo científico publicado en 2012

Starting a lung transplant program: a roadmap for long-term excellence

artículo científico publicado en 2015

TLR4 mutations are associated with endotoxin hyporesponsiveness in humans

artículo científico publicado en 2000

Targeting the urokinase plasminogen activator receptor enhances gene transfer to human airway epithelia.

artículo científico publicado en 2000

The Coxsackievirus and Adenovirus Receptor: a new adhesion protein in cochlear development

scientific journal article

The Effects of Timed Light Exposure in Critically Ill Patients: A Randomized Controlled Pilot Clinical Trial

artículo científico publicado en 2018

The air-liquid interface and use of primary cell cultures are important to recapitulate the transcriptional profile of in vivo airway epithelia

artículo científico publicado en 2010

The indirect effect of Tityus discrepans on rabbit pulmonary vasculature.

artículo científico publicado en 2003

The porcine lung as a potential model for cystic fibrosis

artículo científico publicado en 2008

The ΔF508 mutation causes CFTR misprocessing and cystic fibrosis-like disease in pigs

artículo científico publicado en 2011

Thixotropic solutions enhance viral-mediated gene transfer to airway epithelia.

artículo científico publicado en 2002

Transepithelial migration of neutrophils into the lung requires TREM-1

scientific journal article

Tryptase does not alter transepithelial conductance or paracellular permeability in human airway epithelial cells.

artículo científico publicado en 2010

Upregulation of pirin expression by chronic cigarette smoking is associated with bronchial epithelial cell apoptosis.

artículo científico publicado en 2007

Whole exome sequencing identifies novel candidate genes that modify chronic obstructive pulmonary disease susceptibility

artículo científico publicado en 2016

pH modulates the activity and synergism of the airway surface liquid antimicrobials β-defensin-3 and LL-37

artículo científico publicado en 2014

Lista de obras de Joseph Zabner

A common mutation in paraoxonase-2 results in impaired lactonase activity.

A low rate of cell proliferation and reduced DNA uptake limit cationic lipid-mediated gene transfer to primary cultures of ciliated human airway epithelia ⬇️

A mouse model for the delta F508 allele of cystic fibrosis.

A novel host defense system of airways is defective in cystic fibrosis

A role for the PDZ-binding domain of the coxsackie B virus and adenovirus receptor (CAR) in cell adhesion and growth

A shortened adeno-associated virus expression cassette for CFTR gene transfer to cystic fibrosis airway epithelia.

Absence of amiloride-sensitive sodium absorption in the airway of an infant with pseudohypoaldosteronism

Abundant DNase I-Sensitive Bacterial DNA in Healthy Porcine Lungs and Its Implications for the Lung Microbiome ⬇️

Adenoviral gene transfer corrects the ion transport defect in the sinus epithelia of a porcine CF model

Adenoviral-mediated gene transfer to fetal pulmonary epithelia in vitro and in vivo.

Adenovirus 5-fiber 35 chimeric vector mediates efficient apical correction of the cystic fibrosis transmembrane conductance regulator defect in cystic fibrosis primary airway epithelia.

Adenovirus fiber disrupts CAR-mediated intercellular adhesion allowing virus escape

Adenovirus-mediated gene therapy for head and neck squamous cell carcinomas.

Adenovirus-mediated gene transfer for cystic fibrosis: Part A. Safety of dose and repeat administration in the nasal epithelium. Part B. Clinical efficacy in the maxillary sinus

Adenovirus-mediated gene transfer transiently corrects the chloride transport defect in nasal epithelia of patients with cystic fibrosis.

Aggregates of mutant CFTR fragments in airway epithelial cells of CF lungs: new pathologic observations

Airway acidification initiates host defense abnormalities in cystic fibrosis mice.

Airway surface liquid from smokers promotes bacterial growth and biofilm formation via iron-lactoferrin imbalance.

Alveolar macrophages inhibit retrovirus-mediated gene transfer to airway epithelia.

Apical localization of the coxsackie-adenovirus receptor by glycosyl-phosphatidylinositol modification is sufficient for adenovirus-mediated gene transfer through the apical surface of human airway epithelia

Augmentation of lung liquid clearance via adenovirus-mediated transfer of a Na,K-ATPase beta1 subunit gene ⬇️

Bronchoalveolar fluid is not a major hindrance to virus-mediated gene therapy in cystic fibrosis.

Bronchoscopic assessment of airway retention time of aerosolized xylitol.

CFTR DeltaF508 mutation has minimal effect on the gene expression profile of differentiated human airway epithelia

CFTR gene transfer with AAV improves early cystic fibrosis pig phenotypes

CFTR is required for maximal transepithelial liquid transport in pig alveolar epithelia

Canine adenovirus vectors for lung-directed gene transfer: efficacy, immune response, and duration of transgene expression using helper-dependent vectors.

Cationic lipid mediated gene transfer of CFTR: safety of a single administration to the nasal epithelia

Cationic lipid-mediated transfer of the hIL-10 gene prolongs survival of allogeneic hepatocytes in Nagase analbuminemic rats

Cellular and Molecular Barriers to Gene Transfer by a Cationic Lipid ⬇️

Cellular localization and activity of Ad-delivered GFP-CFTR in airway epithelial and tracheal cells.

Characterization of fusion genes and the significantly expressed fusion isoforms in breast cancer by hybrid sequencing.

Chest wall strapping increases expiratory airflow and detectable airway segments in computer tomographic scans of normal and obstructed lungs.

Comparison of DNA-lipid complexes and DNA alone for gene transfer to cystic fibrosis airway epithelia in vivo ⬇️

Complexes of adenovirus with polycationic polymers and cationic lipids increase the efficiency of gene transfer in vitro and in vivo.

Concentration of the antibacterial precursor thiocyanate in cystic fibrosis airway secretions

Correction of cAMP-stimulated fluid secretion in cystic fibrosis airway epithelia: efficiency of adenovirus-mediated gene transfer in vitro

Cystic Fibrosis Transmembrane Conductance Regulator Potentiation as a Therapeutic Strategy for Pulmonary Edema: A Proof-of-Concept Study in Pigs.

Cystic fibrosis pigs develop lung disease and exhibit defective bacterial eradication at birth

DEVELOPMENT OF A POLARIZED PANCREATIC DUCTULAR CELL EPITHELIA FOR PHYSIOLOGICAL STUDIES.

Differential expression of sheep beta-defensin-1 and -2 and interleukin 8 during acute Mannheimia haemolytica pneumonia.

Differentiation of human airway epithelia is dependent on erbB2

Directed evolution of adeno-associated virus to an infectious respiratory virus

Disruption of the CFTR gene produces a model of cystic fibrosis in newborn pigs

Do cell junction protein mutations cause an airway phenotype in mice or humans?

Drosophila are protected from Pseudomonas aeruginosa lethality by transgenic expression of paraoxonase-1.

Dual therapeutic utility of proteasome modulating agents for pharmaco-gene therapy of the cystic fibrosis airway.

Effect of vitamin D3 on the antimicrobial activity of human airway surface liquid: preliminary results of a randomised placebo-controlled double-blind trial.

Effects of Coal Fly Ash Particulate Matter on the Antimicrobial Activity of Airway Surface Liquid

Electrolyte transport properties in distal small airways from cystic fibrosis pigs with implications for host defense

Enamel pathology resulting from loss of function in the cystic fibrosis transmembrane conductance regulator in a porcine animal model

Enhanced sialic acid-dependent endocytosis explains the increased efficiency of infection of airway epithelia by a novel adeno-associated virus

Evaluation of in vivo total and regional air content and distribution in primate lungs with high-resolution CT.

Expression of the complement anaphylatoxin C3a and C5a receptors on bronchial epithelial and smooth muscle cells in models of sepsis and asthma

Feline immunodeficiency virus vectors persistently transduce nondividing airway epithelia and correct the cystic fibrosis defect

Foxj1 is required for apical localization of ezrin in airway epithelial cells

Functional effects of coxsackievirus and adenovirus receptor glycosylation on homophilic adhesion and adenoviral infection.

Gene transfer of CFTR to airway epithelia: low levels of expression are sufficient to correct Cl- transport and overexpression can generate basolateral CFTR.

Gene transfer to airway epithelia using feline immunodeficiency virus-based lentivirus vectors

Glucose depletion in the airway surface liquid is essential for sterility of the airways

Higher BMI is associated with higher expiratory airflow normalised for lung volume (FEF25-75/FVC) in COPD

Histamine alters E-cadherin cell adhesion to increase human airway epithelial permeability.

Hoechst increases adeno-associated virus-mediated transgene expression in airway epithelia by inducing the cytomegalovirus promoter

Human cystic fibrosis airway epithelia have reduced Cl- conductance but not increased Na+ conductance.

Impaired mucus detachment disrupts mucociliary transport in a piglet model of cystic fibrosis.

In Situ Quantification of Glucose Concentration in Airway Surface Liquid With Functionalized ZnO Nanorod-Coated Microelectrodes ⬇️

Inactivation of a Pseudomonas aeruginosa quorum-sensing signal by human airway epithelia.

Incorporation of adenovirus in calcium phosphate precipitates enhances gene transfer to airway epithelia in vitro and in vivo ⬇️

Increasing epithelial junction permeability enhances gene transfer to airway epithelia In vivo.

Inflammatory response in airway epithelial cells isolated from patients with cystic fibrosis.

Integrin α6β4 identifies human distal lung epithelial progenitor cells with potential as a cell-based therapy for cystic fibrosis lung disease

Interdependency of beta-adrenergic receptors and CFTR in regulation of alveolar active Na+ transport.

Interleukin-9 induces goblet cell hyperplasia during repair of human airway epithelia

Intestinal CFTR expression alleviates meconium ileus in cystic fibrosis pigs

Iron oxide nanoparticles induce Pseudomonas aeruginosa growth, induce biofilm formation, and inhibit antimicrobial peptide function

Isoform-specific regulation and localization of the coxsackie and adenovirus receptor in human airway epithelia

Ivacaftor-induced sweat chloride reductions correlate with increases in airway surface liquid pH in cystic fibrosis

Keratinocyte growth factor induced epithelial proliferation facilitates retroviral–mediated gene transfer to distal lung epithelia in vivo

Lack of high affinity fiber receptor activity explains the resistance of ciliated airway epithelia to adenovirus infection