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A Population Pharmacokinetic Model-Guided Evaluation of Ceftolozane-Tazobactam Dosing in Critically Ill Patients Undergoing Continuous Venovenous Hemodiafiltration

scientific article published on 20 December 2019

A UHPLC-MS/MS method for the simultaneous determination of piperacillin and tazobactam in plasma (total and unbound), urine and renal replacement therapy effluent

artículo científico publicado en 2017

A pharmacokinetic case study of intravenous posaconazole in a critically ill patient with hypoalbuminaemia receiving continuous venovenous haemodiafiltration

scientific article published on 19 July 2018

A simple LC–MS/MS method using HILIC chromatography for the determination of fosfomycin in plasma and urine: Application to a pilot pharmacokinetic study in humans

artículo científico publicado en 2014

A validated UHPLC-MS/MS method for the measurement of riluzole in plasma and myocardial tissue samples

artículo científico publicado en 2017

A validated method for the quantification of fosfomycin on dried plasma spots by HPLC-MS/MS: application to a pilot pharmacokinetic study in humans

artículo científico publicado en 2015

ASAP ECMO: Antibiotic, Sedative and Analgesic Pharmacokinetics during Extracorporeal Membrane Oxygenation: a multi-centre study to optimise drug therapy during ECMO.

artículo científico publicado en 2012

Altered antibiotic pharmacokinetics during extracorporeal membrane oxygenation: cause for concern?

article

An LC–MS/MS method to determine vancomycin in plasma (total and unbound), urine and renal replacement therapy effluent

artículo científico publicado en 2017

An UHPLC-MS/MS method for the simultaneous determination of ampicillin and sulbactam in human plasma and urine

artículo científico publicado en 2015

Analysis of 12 beta-lactam antibiotics in human plasma by HPLC with ultraviolet detection

artículo científico publicado en 2010

Are interstitial fluid concentrations of meropenem equivalent to plasma concentrations in critically ill patients receiving continuous renal replacement therapy?

artículo científico publicado en 2014

Are standard doses of piperacillin sufficient for critically ill patients with augmented creatinine clearance?

artículo científico publicado en 2015

Assays for therapeutic drug monitoring of β-lactam antibiotics: A structured review

artículo científico

Beta-Lactam Infusion in Severe Sepsis (BLISS): a prospective, two-centre, open-labelled randomised controlled trial of continuous versus intermittent beta-lactam infusion in critically ill patients with severe sepsis.

artículo científico publicado en 2016

Binding of Local Anaesthetics to the Lipid Emulsion Clinoleic™ 20%

artículo científico publicado el 1 de septiembre de 2013

Can we use an ex vivo continuous hemofiltration model to describe the adsorption and elimination of meropenem and piperacillin?

artículo científico publicado en 2015

Caspofungin Population Pharmacokinetics in Critically Ill Patients Undergoing Continuous Veno-Venous Haemofiltration or Haemodiafiltration

artículo científico

Cerebrospinal fluid penetration of ceftolozane/tazobactam in critically ill patients with an indwelling external ventricular drain

artículo científico publicado en 2020

Cerebrospinal fluid penetration of high doses of intravenous ciprofloxacin in meningitis.

artículo científico publicado en 2000

Characterization of Effects of Renal Replacement Therapy Modalities and Settings on Pharmacokinetics of Meropenem and Vaborbactam

scientific article published on 24 September 2018

Comparison of equal doses of continuous venovenous haemofiltration and haemodiafiltration on ciprofloxacin population pharmacokinetics in critically ill patients

artículo científico publicado en 2016

Copper(II) complexes of the fluoroquinolone antimicrobial ciprofloxacin. Synthesis, X-ray structural characterization, and potentiometric study

artículo científico publicado en 1996

DALI: Defining Antibiotic Levels in Intensive care unit patients: a multi-centre point of prevalence study to determine whether contemporary antibiotic dosing for critically ill patients is therapeutic

artículo científico publicado en 2012

Determination of Cefalothin and Cefazolin in Human Plasma, Urine and Peritoneal Dialysate by UHPLC-MS/MS: application to a pilot pharmacokinetic study in humans

artículo científico publicado en 2015

Determining the mechanisms underlying augmented renal drug clearance in the critically ill: use of exogenous marker compounds

artículo científico publicado en 2014

Does contemporary vancomycin dosing achieve therapeutic targets in a heterogeneous clinical cohort of critically ill patients? Data from the multinational DALI study

artículo científico publicado en 2014

Doripenem population pharmacokinetics and dosing requirements for critically ill patients receiving continuous venovenous haemodiafiltration

artículo científico publicado en 2014

Effect of Obesity on the Population Pharmacokinetics of Fluconazole in Critically Ill Patients

scientific article published on 22 August 2016

Effect of Obesity on the Population Pharmacokinetics of Meropenem in Critically Ill Patients

artículo científico publicado en 2016

Effect of different renal function on antibacterial effects of piperacillin against Pseudomonas aeruginosa evaluated via the hollow-fibre infection model and mechanism-based modelling.

artículo científico publicado en 2016

Effect of time on recovery of plasma microsamples for the quantitative determination of vancomycin

artículo científico publicado en 2016

Flucloxacillin dosing in critically ill patients with hypoalbuminaemia: special emphasis on unbound pharmacokinetics

artículo científico publicado en 2010

Impact of renal replacement modalities on the clearance of piperacillin-tazobactam administered via continuous infusion in critically ill patients

artículo científico publicado en 2017

Influence of Renal Replacement Modalities on Amikacin Population Pharmacokinetics in Critically Ill Patients on Continuous Renal Replacement Therapy

artículo científico publicado en 2016

Interaction of norfloxacin with divalent and trivalent pharmaceutical cations. In vitro complexation and in vivo pharmacokinetic studies in the dog

scientific article published on 01 August 1996

Intravascular administration sets are accurate and in appropriate condition after 7 days of continuous use: an in vitro study

scientific article published on 01 February 2002

Is prolonged infusion of piperacillin/tazobactam and meropenem in critically ill patients associated with improved pharmacokinetic/pharmacodynamic and patient outcomes? An observation from the Defining Antibiotic Levels in Intensive care unit patien

artículo científico publicado en 2015

Is there a role for microsampling in antibiotic pharmacokinetic studies?

artículo científico publicado en 2016

Low cefpirome levels during twice daily dosing in critically ill septic patients: pharmacokinetic modelling calls for more frequent dosing.

artículo científico publicado en 2001

Meropenem and piperacillin/tazobactam prescribing in critically ill patients: does augmented renal clearance affect pharmacokinetic/pharmacodynamic target attainment when extended infusions are used?

artículo científico publicado en 2013

Meropenem dosing in critically ill patients with sepsis receiving high-volume continuous venovenous hemofiltration

artículo científico publicado en 2010

Optimising meropenem dosing in critically ill Australian Indigenous patients with severe sepsis

artículo científico publicado en 2016

Oral ciprofloxacin activity against ceftriaxone-resistant <i>Escherichia coli</i> in an <i>in vitro</i> bladder infection model

artículo científico publicado en 2022

Pharmacodynamic evaluation of intermittent versus extended and continuous infusions of piperacillin/tazobactam in a hollow-fibre infection model against <i>Escherichia coli</i> clinical isolates

artículo científico publicado en 2022

Pharmacodynamic evaluation of piperacillin/tazobactam against extended-spectrum β-lactamase (ESBL)-producing versus non-ESBL-producing Escherichia coli in a hollow-fibre infection model

artículo científico publicado en 2022

Pharmacodynamic evaluation of piperacillin/tazobactam versus meropenem against extended-spectrum β-lactamase-producing and non-producing <i>Escherichia coli</i> clinical isolates in a hollow-fibre infection model

artículo científico publicado en 2022

Pharmacokinetic variability and exposures of fluconazole, anidulafungin, and caspofungin in intensive care unit patients: Data from multinational Defining Antibiotic Levels in Intensive care unit (DALI) patients Study

artículo científico publicado en 2015

Pharmacokinetics of Intraperitoneal Cefalothin and Cefazolin in Patients Being Treated for Peritoneal Dialysis-Associated Peritonitis

artículo científico publicado en 2016

Pharmacokinetics of Intravenous Posaconazole in Critically Ill Patients

artículo científico publicado en 2018

Pharmacokinetics of Piperacillin in Critically Ill Australian Indigenous Patients with Severe Sepsis

artículo científico publicado en 2016

Pharmacokinetics of intraperitoneal gentamicin in peritoneal dialysis patients with peritonitis (GIPD study).

artículo científico publicado en 2012

Pharmacokinetics of meropenem and piperacillin in critically ill patients with indwelling surgical drains

artículo científico publicado en 2013

Pharmacokinetics of meropenem in critically ill patients receiving continuous venovenous haemofiltration: a randomised controlled trial of continuous infusion versus intermittent bolus administration

artículo científico publicado en 2014

Pharmacokinetics of piperacillin in critically ill patients receiving continuous venovenous haemofiltration: A randomised controlled trial of continuous infusion versus intermittent bolus administration

artículo científico publicado en 2015

Plasma and target-site subcutaneous tissue population pharmacokinetics and dosing simulations of cefazolin in post-trauma critically ill patients

artículo científico publicado en 2015

Plasma and tissue pharmacokinetics of cefazolin in patients undergoing elective and semielective abdominal aortic aneurysm open repair surgery

artículo científico publicado en 2011

Population Pharmacokinetics of Doripenem in Critically Ill Patients with Sepsis in a Malaysian Intensive Care Unit.

artículo científico publicado en 2015

Population Pharmacokinetics of Fosfomycin in Critically Ill Patients.

artículo científico publicado en 2015

Population Pharmacokinetics of Piperacillin in Nonobese, Obese, and Morbidly Obese Critically Ill Patients

artículo científico publicado en 2017

Population Pharmacokinetics of Unbound Ceftolozane and Tazobactam in Critically Ill Patients without Renal Dysfunction

scientific article published on 23 September 2019

Propylene Glycol and Glycerol Concentration in Ultrasound Gel

artículo científico publicado el 1 de enero de 2013

Quantitative bioanalytical validation of fosfomycin in human whole blood with volumetric absorptive microsampling

artículo científico publicado en 2015

Rapid and economical high-performance liquid chromatographic method for the determination of norfloxacin in serum using a microparticulate C18 guard cartridge

scientific article published on 01 December 1995

Reply to Rhodes et al.

artículo científico publicado en 2014

SaMpling Antibiotics in Renal Replacement Therapy (SMARRT): an observational pharmacokinetic study in critically ill patients

artículo científico publicado en 2016

Sequestration of drugs in the circuit may lead to therapeutic failure during extracorporeal membrane oxygenation

artículo científico publicado en 2012

Stability of Antibiotics for Intraperitoneal Administration in Extraneal 7.5% Icodextrin Peritoneal Dialysis Bags (STAB Study).

artículo científico publicado en 2015

Substantial Impact of Altered Pharmacokinetics in Critically Ill Patients on the Antibacterial Effects of Meropenem Evaluated via the Dynamic Hollow-Fiber Infection Model

artículo científico publicado en 2017

The combined effects of extracorporeal membrane oxygenation and renal replacement therapy on meropenem pharmacokinetics: a matched cohort study

artículo científico publicado en 2014

Total and unbound ceftriaxone pharmacokinetics in critically ill Australian Indigenous patients with severe sepsis.

artículo científico publicado en 2016