Lista de obras - Shawn Williams - Dominio Público Uruguay

2-Amino-9-aryl-3-cyano-4-methyl-7-oxo-6,7,8,9-tetrahydropyrido[2',3':4,5]thieno[2,3-b]pyridine derivatives as selective progesterone receptor agonists.

artículo científico publicado en 2009

A characterisation of dark-field imaging of colloidal gold labels in a scanning transmission X-ray microscope.

artículo científico publicado en 1996

A human fatty acid synthase inhibitor binds β-ketoacyl reductase in the keto-substrate site

artículo científico publicado en 2014

A structural and in vitro characterization of asoprisnil: a selective progesterone receptor modulator

artículo científico publicado en 2007

An orally available, brain-penetrant CAMKK2 inhibitor reduces food intake in rodent model.

artículo científico publicado en 2018

Atomic structure of progesterone complexed with its receptor ⬇️

artículo científico publicado el 28 de mayo de 1998

Chemical contrast in X-ray microscopy and spatially resolved XANES spectroscopy of organic specimens

artículo científico publicado el 6 de noviembre de 1992

Chromatin fibers are left-handed double helices with diameter and mass per unit length that depend on linker length.

artículo científico publicado en 1986

Conformationally constrained farnesoid X receptor (FXR) agonists: Naphthoic acid-based analogs of GW 4064

artículo científico publicado en 2008

Conformationally constrained farnesoid X receptor (FXR) agonists: alternative replacements of the stilbene

artículo científico publicado en 2011

Conformationally constrained farnesoid X receptor (FXR) agonists: heteroaryl replacements of the naphthalene

artículo científico publicado en 2011

Crystallization of protein-ligand complexes.

artículo científico publicado en 2006

Crystallographic comparison of the estrogen and progesterone receptor’s ligand binding domains ⬇️

artículo científico publicado el 26 de mayo de 1998

Diffraction-limited imaging in a scanning transmission x-ray microscope

artículo científico publicado en 1991

Discovery of orally active, pyrrolidinone-based progesterone receptor partial agonists.

artículo científico publicado en 2009

FXR agonist activity of conformationally constrained analogs of GW 4064

artículo científico publicado en 2009

Helix 1/8 interactions influence the activity of nuclear receptor ligand-binding domains.

artículo científico publicado en 2003

Hepatocyte nuclear factor 4 is a transcription factor that constitutively binds fatty acids

artículo científico publicado en 2002

Micro-XANES: Chemical contrast in the scanning transmission X-ray microscope

artículo científico publicado en 1994

New results in soft X-ray microscopy

artículo científico publicado en 1994

Progesterone receptor ligand binding pocket flexibility: crystal structures of the norethindrone and mometasone furoate complexes.

artículo científico publicado en 2004

Recent applications of protein crystallography and structure-guided drug design.

artículo científico publicado en 2005

Small Molecule Agonists of the Orphan Nuclear Receptors Steroidogenic Factor-1 (SF-1, NR5A1) and Liver Receptor Homologue-1 (LRH-1, NR5A2)

artículo científico publicado en 2011

Soft x‐ray microscopy with coherent x rays (invited)

artículo científico publicado en 1992

Structural analyses reveal phosphatidyl inositols as ligands for the NR5 orphan receptors SF-1 and LRH-1.

artículo científico publicado en 2005

Structure of Rev-erbα bound to N-CoR reveals a unique mechanism of nuclear receptor–co-repressor interaction

artículo científico publicado en 2010

Structure-guided design of N-phenyl tertiary amines as transrepression-selective liver X receptor modulators with anti-inflammatory activity

artículo científico publicado en 2008

Substituted isoxazole analogs of farnesoid X receptor (FXR) agonist GW4064

artículo científico publicado en 2009

Synthesis of 3-alkyl naphthalenes as novel estrogen receptor ligands

artículo científico publicado en 2008

The Drosophila nuclear receptor e75 contains heme and is gas responsive

artículo científico publicado en 2005

The evolution of progesterone receptor ligands.

artículo científico publicado en 2007

The first X-ray crystal structure of the glucocorticoid receptor bound to a non-steroidal agonist

artículo científico publicado en 2008

X-ray crystal structure of the liver X receptor beta ligand binding domain: regulation by a histidine-tryptophan switch

artículo científico publicado en 2003

Lista de obras de Shawn Williams

2-Amino-9-aryl-3-cyano-4-methyl-7-oxo-6,7,8,9-tetrahydropyrido[2',3':4,5]thieno[2,3-b]pyridine derivatives as selective progesterone receptor agonists.

A characterisation of dark-field imaging of colloidal gold labels in a scanning transmission X-ray microscope.

A human fatty acid synthase inhibitor binds β-ketoacyl reductase in the keto-substrate site

A structural and in vitro characterization of asoprisnil: a selective progesterone receptor modulator

An orally available, brain-penetrant CAMKK2 inhibitor reduces food intake in rodent model.

Atomic structure of progesterone complexed with its receptor ⬇️

Chemical contrast in X-ray microscopy and spatially resolved XANES spectroscopy of organic specimens

Chromatin fibers are left-handed double helices with diameter and mass per unit length that depend on linker length.

Conformationally constrained farnesoid X receptor (FXR) agonists: Naphthoic acid-based analogs of GW 4064

Conformationally constrained farnesoid X receptor (FXR) agonists: alternative replacements of the stilbene

Conformationally constrained farnesoid X receptor (FXR) agonists: heteroaryl replacements of the naphthalene

Crystallization of protein-ligand complexes.

Crystallographic comparison of the estrogen and progesterone receptor’s ligand binding domains ⬇️

Diffraction-limited imaging in a scanning transmission x-ray microscope

Discovery of orally active, pyrrolidinone-based progesterone receptor partial agonists.

FXR agonist activity of conformationally constrained analogs of GW 4064

Helix 1/8 interactions influence the activity of nuclear receptor ligand-binding domains.

Hepatocyte nuclear factor 4 is a transcription factor that constitutively binds fatty acids

Micro-XANES: Chemical contrast in the scanning transmission X-ray microscope

New results in soft X-ray microscopy

Progesterone receptor ligand binding pocket flexibility: crystal structures of the norethindrone and mometasone furoate complexes.

Recent applications of protein crystallography and structure-guided drug design.

Small Molecule Agonists of the Orphan Nuclear Receptors Steroidogenic Factor-1 (SF-1, NR5A1) and Liver Receptor Homologue-1 (LRH-1, NR5A2)

Soft x‐ray microscopy with coherent x rays (invited)

Structural analyses reveal phosphatidyl inositols as ligands for the NR5 orphan receptors SF-1 and LRH-1.

Structure of Rev-erbα bound to N-CoR reveals a unique mechanism of nuclear receptor–co-repressor interaction

Structure-guided design of N-phenyl tertiary amines as transrepression-selective liver X receptor modulators with anti-inflammatory activity

Substituted isoxazole analogs of farnesoid X receptor (FXR) agonist GW4064

Synthesis of 3-alkyl naphthalenes as novel estrogen receptor ligands

The Drosophila nuclear receptor e75 contains heme and is gas responsive

The evolution of progesterone receptor ligands.

The first X-ray crystal structure of the glucocorticoid receptor bound to a non-steroidal agonist

X-ray crystal structure of the liver X receptor beta ligand binding domain: regulation by a histidine-tryptophan switch